Browsing Institutt for klinisk medisin by Title

Now showing items 1955-1974 of 10711

  • Colorectal cancer and IBD in Norway : A retrospective analysis 
    Brackmann, Stephan (Doctoral thesis / Doktoravhandling, 2009)
    Tykktarmskreft ved inflammatorisk tarmsykdom i Norge <br><br> Lege og forsker Stephan Brackmann har kartlagt risikofaktorer for tykktarmskreft ved inflammatorisk tarmsykdom (IBD). Resultatene antyder to ulike typer ...
  • Colorectal cancer in Ulcerative Colitis: A prospective study of clinical and biological markers in population based cohorts 
    Klepp, Pasquale (Doctoral thesis / Doktoravhandling, 2022)
    A significant number of IBD patients still develop colitis associated colorectal cancer (CACRC). Guidelines, therefore, recommend colonoscopic surveillance at intervals based on a patient´s individual risk determined by ...
  • Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium 
    Møller, Pål; Seppälä, Toni; Dowty, James G.; Haupt, Saskia; Dominguez-Valentin, Mev; Sunde, Lone; Bernstein, Inge; Engel, Christoph; Aretz, Stefan; Nielsen, Maartje; Capella, Gabriel; Evans, Dafydd G.; Burn, John; Holinski-Feder, Elke; Bertario, Lucio; Bonanni, Bernardo; Lindblom, Annika; Levi, Zohar; Macrae, Finlay; Winship, Ingrid; Plazzer, John-Paul; Sijmons, Rolf; Laghi, Luigi; Valle, Adriana D.; Heinimann, Karl; Half, Elizabeth; Lopez-Koestner, Francisco; Alvarez-Valenzuela, Karin; Scott, Rodney J.; Katz, Lior; Laish, Ido; Vainer, Elez; Vaccaro, Carlos A.; Carraro, Dirce M.; Gluck, Nathan; Abu-Freha, Naim; Stakelum, Aine; Kennelly, Rory; Winter, Des; Rossi, Benedito M.; Greenblatt, Marc; Bohorquez, Mabel; Sheth, Harsh; Tibiletti, Maria G.; Lino-Silva, Leonardo S.; Horisberger, Karoline; Portenkirchner, Carmen; Nascimento, Ivana; Rossi, Norma T.; da Silva, Leandro A.; Thomas, Huw; Zaránd, Attila; Mecklin, Jukka-Pekka; Pylvänäinen, Kirsi; Renkonen-Sinisalo, Laura; Lepisto, Anna; Peltomäki, Päivi; Therkildsen, Christina; Lindberg, Lars J.; Thorlacius-Ussing, Ole; von Knebel Doeberitz, Magnus; Loeffler, Markus; Rahner, Nils; Steinke-Lange, Verena; Schmiegel, Wolff; Vangala, Deepak; Perne, Claudia; Hüneburg, Robert; de Vargas, Aída F.; Latchford, Andrew; Gerdes, Anne-Marie; Backman, Ann-Sofie; Guillén-Ponce, Carmen; Snyder, Carrie; Lautrup, Charlotte K.; Amor, David; Palmero, Edenir; Stoffel, Elena; Duijkers, Floor; Hall, Michael J.; Hampel, Heather; Williams, Heinric; Okkels, Henrik; Lubiński, Jan; Reece, Jeanette; Ngeow, Joanne; Guillem, Jose G.; Arnold, Julie; Wadt, Karin; Monahan, Kevin; Senter, Leigha; Rasmussen, Lene J.; van Hest, Liselotte P.; Ricciardiello, Luigi; Kohonen-Corish, Maija R. J.; Ligtenberg, Marjolijn J. L.; Southey, Melissa; Aronson, Melyssa; Zahary, Mohd N.; Samadder, N. J.; Poplawski, Nicola; Hoogerbrugge, Nicoline; Morrison, Patrick J.; James, Paul; Lee, Grant; Chen-Shtoyerman, Rakefet; Ankathil, Ravindran; Pai, Rish; Ward, Robyn; Parry, Susan; Dębniak, Tadeusz; John, Thomas; van Overeem Hansen, Thomas; Caldés, Trinidad; Yamaguchi, Tatsuro; Barca-Tierno, Verónica; Garre, Pilar; Cavestro, Giulia M.; Weitz, Jürgen; Redler, Silke; Büttner, Reinhard; Heuveline, Vincent; Hopper, John L.; Win, Aung K.; Lindor, Noralane; Gallinger, Steven; Le Marchand, Loïc; Newcomb, Polly A.; Figueiredo, Jane; Buchanan, Daniel D.; Thibodeau, Stephen N.; ten Broeke, Sanne W.; Hovig, Eivind; Nakken, Sigve; Pineda, Marta; Dueñas, Nuria; Brunet, Joan; Green, Kate; Lalloo, Fiona; Newton, Katie; Crosbie, Emma J.; Mints, Miriam; Tjandra, Douglas; Neffa, Florencia; Esperon, Patricia; Kariv, Revital; Rosner, Guy; Pavicic, Walter H.; Kalfayan, Pablo; Torrezan, Giovana T.; Bassaneze, Thiago; Martin, Claudia; Moslein, Gabriela; Ahadova, Aysel; Kloor, Matthias; Sampson, Julian R.; Jenkins, Mark A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Objective To compare colorectal cancer (CRC) incidences in carriers of pathogenic variants of the MMR genes in the PLSD and IMRC cohorts, of which only the former included mandatory colonoscopy surveillance ...
  • Colorectal cancer screening with repeated fecal immunochemical test versus sigmoidoscopy: baseline results from a randomized trial 
    Randel, Kristin Ranheim; Schult, Anna Lisa; Botteri, Edoardo; Hoff, Geir; Bretthauer, Michael; Ursin, Giske; Natvig, Erik; Berstad, Paula; Jørgensen, Anita; Sandvei, Per Kristian; Olsen, Marie Kristin Ek; Frigstad, Svein Oskar; Darre-Næss, Ole; Norvard, Espen R.; Bolstad, Nils; Kørner, Hartwig; Wibe, Arne; Wensaas, Knut-Arne; de Lange, Thomas; Holme, Øyvind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background and aims: The comparative effectiveness of sigmoidoscopy and fecal immunochemical testing (FIT) for colorectal cancer (CRC) screening is unknown. Methods: Individuals aged 50-74 years living in South-East Norway ...
  • Colorectal cancer – survival trends and prognostic role of circulating cell-free DNA 
    Hamfjord, Julian (Doctoral thesis / Doktoravhandling, 2024)
    Survival of patients with colorectal cancer (CRC) has improved throughout the past forty years, but to date outcomes are heterogeneous. The aims of the thesis were to describe survival trends of colon cancer in Norway and ...
  • Colorectal polypectomy and endoscopic mucosal resection: European Society of Gastrointestinal Endoscopy Cascade Guideline 
    Karstensen, John Gásdal; Ebigbo, Alanna; Desalegn, Hailemichael; Afihene, Mary; Anigbo, Gideon; Antonelli, Giulio; Bhat, Purnima; Duduyemi, Babatunde; Guy, Claire; Ijoma, Uchenna; Ponchon, Thierry; Rahmi, Gabriel; Aabakken, Lars; Hassan, Cesare (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Colorectal cancer (CRC) is a major contributor to morbidity and cancer death globally with an increasing incidence also in low- and middle-income countries [1] [2]. However, CRC is preventable if precursor lesions are ...
  • Colorimetric and Electrochemical Screening for Early Detection of Diabetes Mellitus and Diabetic Retinopathy—Application of Sensor Arrays and Machine Learning 
    Faura Muñoz, Georgina; Boix Lemonche, Gerard; Holmeide, Anne Kristin; Verkauskiene, Rasa; Volke, Vallo; Sokolovska, Jelizaveta; Petrovski, Goran (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    In this review, a selection of works on the sensing of biomarkers related to diabetes mellitus (DM) and diabetic retinopathy (DR) are presented, with the scope of helping and encouraging researchers to design sensor-array ...
  • Colourimetric image analysis as a diagnostic tool in female genital schistosomiasis 
    Holmen, Sigve Dhondup; Kjetland, Eyrun Floerecke; Taylor, Myra; Kleppa, Elisabeth; Lillebø, Kristine; Gundersen, Svein Gunnar; Onsrud, Mathias; Albregtsen, Fritz (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Female genital schistosomiasis (FGS) is a highly prevalent waterborne disease in some of the poorest areas of sub-Saharan Africa. Reliable and affordable diagnostics are unavailable. We explored colourimetric image analysis ...
  • Combination of anti-CD37 radioimmunotherapy with anti-CD20 immunotherapy and small molecule inhibitors to improve therapy of non- Hodgkin lymphoma 
    Malenge, Marion Masitsa (Doctoral thesis / Doktoravhandling, 2020)
    Patients with non- Hodgkin lymphoma (NHL) are often treated with the combination of chemotherapy and CD20 targeting immunotherapy. However, some of these patients develop relapsed or refractory disease after initial ...
  • Combination of Biological Agents in Moderate to Severe Pediatric Inflammatory Bowel Disease: A Case Series and Review of the Literature. 
    Olbjørn, Christine; Rove, Jon Bergreen; Jahnsen, Jørgen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background Treatment with biological agents such as anti-tumor necrosis factors (TNFs) has become standard of care in moderate to severe pediatric inflammatory bowel disease (IBD). However, a significant proportion of ...
  • Combination of ECG and Echocardiography for Identification of Arrhythmic Events in Early ARVC 
    Leren, Ida Skrinde; Saberniak, Jørg; Håland, Trine Synnøve Fink; Edvardsen, Thor; Haugaa, Kristina (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    OBJECTIVES: The aim of this study was to investigate early markers of arrhythmic events (AEs) and improve risk stratification in early arrhythmogenic right ventricular cardiomyopathy (ARVC). BACKGROUND: AEs are frequent ...
  • Combination therapies with HSP90 inhibitors against colorectal cancer 
    Kryeziu, Kushtrim; Bruun, Jarle; Guren, Tormod Kyrre; Sveen, Anita; Lothe, Ragnhild A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Oncogene stability and homeostasis mediated by the HSP90 chaperone is a crucial protection trait of cancer cells. Therefore, HSP90 represents an attractive therapeutic target for many cancers, including colorectal cancer. ...
  • Combinatorial CAR design improves target restriction 
    Köksal, Hakan; Dillard, Pierre; Juzeniene, Asta; Kvalheim, Gunnar; Smeland, Erlend B.; Myklebust, June Helen; Inderberg, Else Marit; Wälchli, Sébastien (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    CAR T cells targeting the B lymphocyte antigen CD19 have led to remarkable clinical results in B cell leukemia and lymphoma but eliminate all B lineage cells, leading to increased susceptibility to severe infections. As ...
  • Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer 
    Salvati, Annamaria; Melone, Viola; Sellitto, Assunta; Rizzo, Francesca; Tarallo, Roberta; Nyman, Tuula A.; Giurato, Giorgio; Nassa, Giovanni; Weisz, Alessandro (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background Targeting vulnerabilities of cancer cells by inhibiting key regulators of cell proliferation or survival represents a promising way to overcome resistance to current therapies. In breast cancer ...
  • Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses 
    Islam, Rakibul; Islam, Mohammad Mirazul; Nilsson, Per H.; Mohlin, Camilla; Hagen, Kjersti Thorvaldsen; Paschalis, Eleftherios I.; Woods, Russell L.; Bhowmick, Sabuj Chandra; Dohlman, Claes H.; Espevik, Terje; Chodosh, James; Gonzalez-Andrades, Miguel; Mollnes, Tom Eirik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Inadequate supplies of donor corneas have evoked an escalating interest in corneal xenotransplantation. However, innate immune responses contribute significantly to the mechanism of xenograft rejection. We hypothesized ...
  • Combined cognitive and vocational interventions after mild to moderate traumatic brain injury: study protocol for a randomized controlled trial 
    Howe, Emilie I; Langlo, Knut-Petter S; Terjesen, Hans C A; Røe, Cecilie; Schanke, Anne-Kristine; Søberg, Helene L; Sveen, Unni; Aas, Eline; Enehaug, Heidi; Alves, Daniele E; Klethagen, Pål; Sagstad, Kjersti; Moen, Christine M; Torsteinsbrend, Karin; Linnestad, Anne-Margrethe; Nordenmark, Tonje H; Rismyhr, Birte S; Wangen, Grete; Lu, Juan; Ponsford, Jennie; Twamley, Elizabeth W; Ugelstad, Helene; Spjelkavik, Øystein; Løvstad, Marianne; Andelic, Nada (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background A considerable proportion of patients with mild to moderate traumatic brain injury (TBI) experience long-lasting somatic, cognitive, and emotional symptoms that may hamper their capacity to ...
  • Combined effect of high factor VIII levels and high mean platelet volume on the risk of future incident venous thromboembolism 
    Hansen, Ellen-Sofie; Edvardsen, Magnus; Aukrust, Pål; Ueland, Thor; Hansen, John Bjarne; Brækkan, Sigrid Kufaas; Morelli, Vania Maris (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2023)
    Background High factor VIII (FVIII) levels and large platelets, as reflected by a high mean platelet volume (MPV), are separately associated with increased risk of venous thromboembolism (VTE). Whether the combination ...
  • Combined group and individual therapy for patients with avoidant personality disorder—A pilot study 
    Wilberg, Theresa; Pedersen, Geir Arild Feigum; Bremer, Kjetil; Johansen, Merete Selsbakk; Kvarstein, Elfrida Hartveit (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Objective Avoidant personality disorder (AvPD) is a common disorder within mental health services, associated with significant psychosocial impairment. The disorder has been neglected in research. There are currently no ...
  • Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome 
    Thomas, Anub Mathew; Schjalm, Camilla; Nilsson, Per; Lindenskov, Paal Helge H.; Rørtveit, Runa; Solberg, Rønnaug; Saugstad, Ola Didrik; Berglund, Magnus M.; Strömberg, Patrik; Lau, Corinna; Espevik, Terje; Jansen, Johan Høgset; Castellheim, Albert; Mollnes, Tom Eirik; Barratt-Due, Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background: Meconium aspiration syndrome (MAS) is a severe lung condition affecting newborns and it can lead to a systemic inflammatory response. We previously documented complement activation and cytokine release in a ...
  • Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis 
    Hellerud, Bernt C; Orrem, Hilde L; Dybwik, Knut; Pischke, Søren E; Baratt-Due, Andreas; Castellheim, Albert; Fure, Hilde; Bergseth, Grethe; Christiansen, Dorte; Nunn, Miles A; Espevik, Terje; Lau, Corinna; Brandtzæg, Petter; Nielsen, Erik W; Mollnes, Tom E (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background Fulminant meningococcal sepsis, characterized by overwhelming innate immune activation, mostly affects young people and causes high mortality. This study aimed to investigate the effect of ...