Now showing items 1142-1161 of 5157

  • Bonsaksen, Tore; Heir, Trond; Skogstad, Laila; Grimholt, Tine K.; Ekeberg, Øivind; Lerdal, Anners; Schou-Bredal, Inger (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
    Purpose Harmful use of alcohol is a major public health problem. While harm is often researched in the context of heavy drinking episodes, high-frequency drinking, even when drinking moderate quantities, constitutes a ...
  • Lagali, Neil S.; Allgeier, Stephan; Guimarães, Pedro; Badian, Reza; Ruggeri, Alfredo; Köhler, Bernd; Utheim, Tor Paaske; Peebo, Beatrice; Peterson, Magnus; Dahlin, Lars B.; Rolandsson, Olov (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    A dense nerve plexus in the clear outer window of the eye, the cornea, can be imaged in vivo to enable non-invasive monitoring of peripheral nerve degeneration in diabetes. However, a limited field of view of corneal nerves, ...
  • Campo, Giuseppe; Pavasini, Rita; Morciano, Giampaolo; Lincoff, Michael A; C Gibson, Michael; Kitakaze, Masafumi; Lonborg, Jacob; Ahluwalia, Amrita; Ishii, Hideki; Frenneaux, Michael; Ovize, Michel; Galvani, Marcello; Atar, Dan; Ibanez, Berta; Cerisano, Giampaolo; Biscaglia, Simone; Neil, Brandon J; Asakura, Masanori; Engstrom, Thomas; Jones, Daniel A; Dawson, Dana; Ferrari, Roberto; Pinton, Paolo; Ottani, Filippo (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Mortality and morbidity in patients with ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) are still high [1]. A huge amount of the myocardial damage is related to the ...
  • Dannenfelser, Ruth; Nome, Marianne Eikhom; Tahiri, Andliena; Ursini-Siegel, Josie; Vollan, Hans Kristian Moen; Haakensen, Vilde Drageset; Helland, Åslaug; Naume, Bjørn; Caldas, Carlos; Børresen-Dale, Anne-Lise; Kristensen, Vessela N.; Troyanskaya, Olga G. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    The tumor microenvironment is now widely recognized for its role in tumor progression, treatment response, and clinical outcome. The intratumoral immunological landscape, in particular, has been shown to exert both ...
  • Simonsen, Trude Golimo; Lund, Kjersti Vassmo; Hompland, Tord; Kristensen, Gunnar S Balle; Rofstad, Einar K (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Purpose: The poor outcome of locally advanced cervical cancer has been associated with extensive hypoxia and high interstitial fluid pressure (IFP) in the primary tumor. In the present study, measures of tumor hypoxia and ...
  • Henriksen, Mari W; Ravn, Kirstine; Paus, Benedicte; von Tetzchner, Stephen; Skjeldal, Ola H (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background Rett syndrome (RTT) is a neurodevelopmental disorder. In more than 95% of females with classic RTT a pathogenic mutation in MECP2 has been identified. This leaves a small fraction of classic cases ...
  • Angell, Inga Leena; Nilsen, Morten; Carlsen, Karin C. Lødrup; Carlsen, Kai-Håkon; Hedlin, Gunilla; Jonassen, Christine M; Marsland, Benjamin; Nordlund, Björn; Rehbinder, Eva Maria; Schinagl, Carina Madelen; Skjerven, Håvard Ove; Staff, Anne Cathrine; Söderhäll, Cilla; Vettukattil, Muhammad Riyas; Rudi, Knut (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Nanopore sequencing is rapidly becoming more popular for use in various microbiota-based applications. Major limitations of current approaches are that they do not enable de novo species identification and that they cannot ...
  • Davidson, Ben; McFadden, Erin; Holth, Arild; Brunetti, Marta; Flørenes, Vivi Ann (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract The objective of this study was to analyze the expression and clinical role of mitosis regulators α-thalassemia/mental retardation syndrome X-linked (ATRX) and death-domain-associated protein (DAXX) in metastatic ...
  • Kjekshus, John (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2001)
    Treatment to prevent progression of heart failure has been targeted to reverse the consequences of heart failure and to a lesser extent the cause – the atherosclerotic plaque itself. Less than 50% of patients with heart ...
  • Bjørshol, Conrad A; Sunde, Kjetil; Myklebust, Helge; Assmus, Jörg; Søreide, Eldar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background The aim of this study was to measure chest compression decay during simulated advanced life support (ALS) in a cardiac arrest manikin model. Methods ...
  • Alnæs-Katjavivi, Patji Haakon (Doctoral thesis / Doktoravhandling, 2020)
    Preeclampsia, a hypertensive disease of pregnancy, impacts on both mother and child health during pregnancy, and adds to the mother’s risk of developing atherosclerotic cardiovascular disease later in life. Underlying ...
  • Bergholtz, Helga (Doctoral thesis / Doktoravhandling, 2020)
    Breast cancer affects over 3500 women in Norway every year. Since the introduction of mammographic screening, early stage breast cancers are diagnosed more frequently and many of these are non-invasive with low potential ...
  • Cassetta, Luca; Bækkevold, Espen Sønderaal; Brandau, Sven; Bujko, Anna; Cassatella, Marco A.; Dorhoi, Anca; Krieg, Carsten; Lin, Ang; Loré, Karin; Marini, Olivia; Pollard, Jeffrey W.; Roussel, Mikael; Scapini, Patrizia; Umansky, Viktor; Adema, Gosse J. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    In cancer, infection and inflammation, the immune system’s function can be dysregulated. Instead of fighting disease, immune cells may increase pathology and suppress host-protective immune responses. Myeloid cells show ...
  • Pfefferle, Aline; Jacobs, Benedikt Marcel; Haroun-Izquierdo, Alvaro; Kveberg, Lise; Sohlberg, Ebba; Malmberg, Karl-Johan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Natural killer (NK) cells have a central role within the innate immune system, eliminating virally infected, foreign and transformed cells through their natural cytotoxic capacity. Release of their cytotoxic granules is ...
  • Yimer, Solomon A; Namouchi, Amine; Zegeye, Ephrem D; Holm-Hansen, Carol; Norheim, Gunnstein; Abebe, Markos; Aseffa, Abraham; Tønjum, Tone (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Background A deeply rooted phylogenetic lineage of Mycobacterium tuberculosis (M. tuberculosis) termed lineage 7 was discovered in Ethiopia. Whole genome sequencing of 30 lineage 7 strains from patients in ...
  • Nunes-Xavier, Caroline Elisabeth; Flem Karlsen, Karine; Tekle, Christina; Pedersen, Cathrine; Øyjord, Tove Ragnhild; Hongisto, Vesa; Nesland, Jahn M; Tan, Ming; Sahlberg, Kristine Kleivi; Fodstad, Øystein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    B7 family proteins are important immune response regulators, and can mediate oncogenic signaling and cancer development. We have used human triple-negative breast cancer cell lines with different expression levels of B7-H3 ...
  • Wang, Zhihui; He, Wei; Yang, Guanrui; Wang, Junsheng; Wang, Zhong; Nesland, Jahn M; Holm, Ruth; Suo, Zhenhe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Background Glutathione S-transferase pi (GST pi) is a subgroup of GST family, which provides cellular protection against free radical and carcinogenic compounds due to its detoxifying function. Expression ...
  • Tveit, Julie Victoria Holm (Doctoral thesis / Doktoravhandling, 2011)
    Concerns for decreased fetal movements (DFM) is a frequent cause of unplanned health consultations throughout the third trimester ranging between 4 % - 16 % in various populations. In the present thesis, women in the ...
  • Akkouh, Ibrahim; Ueland, Thor; Hansson, Lars; Inderhaug, Elin; Hughes, Timothy; Steen, Nils Eiel; Aukrust, Pål; Andreassen, Ole Andreas; Szabo, Attila; Djurovic, Srdjan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Schizophrenia (SCZ) is a severe mental disorder with a high heritability. Although its pathophysiology is mainly unknown, dysregulated immune activation and inflammation have recently emerged as possible candidates in the ...
  • Ernst, Gernot Walter; Watne, Leiv Otto; Frihagen, Frede Jon; Wyller, Torgeir Bruun; Dominik, Andreas; Rostrup, Morten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)