Now showing items 1073-1092 of 4871

  • Lagali, Neil S.; Allgeier, Stephan; Guimarães, Pedro; Badian, Reza; Ruggeri, Alfredo; Köhler, Bernd; Utheim, Tor Paaske; Peebo, Beatrice; Peterson, Magnus; Dahlin, Lars B.; Rolandsson, Olov (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    A dense nerve plexus in the clear outer window of the eye, the cornea, can be imaged in vivo to enable non-invasive monitoring of peripheral nerve degeneration in diabetes. However, a limited field of view of corneal nerves, ...
  • Campo, Giuseppe; Pavasini, Rita; Morciano, Giampaolo; Lincoff, Michael A; C Gibson, Michael; Kitakaze, Masafumi; Lonborg, Jacob; Ahluwalia, Amrita; Ishii, Hideki; Frenneaux, Michael; Ovize, Michel; Galvani, Marcello; Atar, Dan; Ibanez, Berta; Cerisano, Giampaolo; Biscaglia, Simone; Neil, Brandon J; Asakura, Masanori; Engstrom, Thomas; Jones, Daniel A; Dawson, Dana; Ferrari, Roberto; Pinton, Paolo; Ottani, Filippo (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Mortality and morbidity in patients with ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) are still high [1]. A huge amount of the myocardial damage is related to the ...
  • Dannenfelser, Ruth; Nome, Marianne Eikhom; Tahiri, Andliena; Ursini-Siegel, Josie; Vollan, Hans Kristian Moen; Haakensen, Vilde Drageset; Helland, Åslaug; Naume, Bjørn; Caldas, Carlos; Børresen-Dale, Anne-Lise; Kristensen, Vessela N.; Troyanskaya, Olga G. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    The tumor microenvironment is now widely recognized for its role in tumor progression, treatment response, and clinical outcome. The intratumoral immunological landscape, in particular, has been shown to exert both ...
  • Simonsen, Trude Golimo; Lund, Kjersti Vassmo; Hompland, Tord; Kristensen, Gunnar S Balle; Rofstad, Einar K (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Purpose: The poor outcome of locally advanced cervical cancer has been associated with extensive hypoxia and high interstitial fluid pressure (IFP) in the primary tumor. In the present study, measures of tumor hypoxia and ...
  • Henriksen, Mari W; Ravn, Kirstine; Paus, Benedicte; von Tetzchner, Stephen; Skjeldal, Ola H (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background Rett syndrome (RTT) is a neurodevelopmental disorder. In more than 95% of females with classic RTT a pathogenic mutation in MECP2 has been identified. This leaves a small fraction of classic cases ...
  • Kjekshus, John (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2001)
    Treatment to prevent progression of heart failure has been targeted to reverse the consequences of heart failure and to a lesser extent the cause – the atherosclerotic plaque itself. Less than 50% of patients with heart ...
  • Bjørshol, Conrad A; Sunde, Kjetil; Myklebust, Helge; Assmus, Jörg; Søreide, Eldar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background The aim of this study was to measure chest compression decay during simulated advanced life support (ALS) in a cardiac arrest manikin model. Methods ...
  • Alnæs-Katjavivi, Patji Haakon (Doctoral thesis / Doktoravhandling, 2020)
    Preeclampsia, a hypertensive disease of pregnancy, impacts on both mother and child health during pregnancy, and adds to the mother’s risk of developing atherosclerotic cardiovascular disease later in life. Underlying ...
  • Bergholtz, Helga (Doctoral thesis / Doktoravhandling, 2020)
    Breast cancer affects over 3500 women in Norway every year. Since the introduction of mammographic screening, early stage breast cancers are diagnosed more frequently and many of these are non-invasive with low potential ...
  • Cassetta, Luca; Bækkevold, Espen Sønderaal; Brandau, Sven; Bujko, Anna; Cassatella, Marco A.; Dorhoi, Anca; Krieg, Carsten; Lin, Ang; Loré, Karin; Marini, Olivia; Pollard, Jeffrey W.; Roussel, Mikael; Scapini, Patrizia; Umansky, Viktor; Adema, Gosse J. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    In cancer, infection and inflammation, the immune system’s function can be dysregulated. Instead of fighting disease, immune cells may increase pathology and suppress host-protective immune responses. Myeloid cells show ...
  • Pfefferle, Aline; Jacobs, Benedikt Marcel; Haroun-Izquierdo, Alvaro; Kveberg, Lise; Sohlberg, Ebba; Malmberg, Karl-Johan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Natural killer (NK) cells have a central role within the innate immune system, eliminating virally infected, foreign and transformed cells through their natural cytotoxic capacity. Release of their cytotoxic granules is ...
  • Yimer, Solomon A; Namouchi, Amine; Zegeye, Ephrem D; Holm-Hansen, Carol; Norheim, Gunnstein; Abebe, Markos; Aseffa, Abraham; Tønjum, Tone (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Background A deeply rooted phylogenetic lineage of Mycobacterium tuberculosis (M. tuberculosis) termed lineage 7 was discovered in Ethiopia. Whole genome sequencing of 30 lineage 7 strains from patients in ...
  • Nunes-Xavier, Caroline Elisabeth; Flem Karlsen, Karine; Tekle, Christina; Pedersen, Cathrine; Øyjord, Tove Ragnhild; Hongisto, Vesa; Nesland, Jahn M; Tan, Ming; Sahlberg, Kristine Kleivi; Fodstad, Øystein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    B7 family proteins are important immune response regulators, and can mediate oncogenic signaling and cancer development. We have used human triple-negative breast cancer cell lines with different expression levels of B7-H3 ...
  • Wang, Zhihui; He, Wei; Yang, Guanrui; Wang, Junsheng; Wang, Zhong; Nesland, Jahn M; Holm, Ruth; Suo, Zhenhe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Background Glutathione S-transferase pi (GST pi) is a subgroup of GST family, which provides cellular protection against free radical and carcinogenic compounds due to its detoxifying function. Expression ...
  • Tveit, Julie Victoria Holm (Doctoral thesis / Doktoravhandling, 2011)
    Concerns for decreased fetal movements (DFM) is a frequent cause of unplanned health consultations throughout the third trimester ranging between 4 % - 16 % in various populations. In the present thesis, women in the ...
  • Ernst, Gernot Walter; Watne, Leiv Otto; Frihagen, Frede Jon; Wyller, Torgeir Bruun; Dominik, Andreas; Rostrup, Morten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
  • Nilssen, Yngvar; Brustugun, Odd Terje; Eriksen, Morten Tandberg; Gulbrandsen, Johanne; Haug, Erik Skaaheim; Naume, Bjørn; Møller, Bjørn (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Background: In 2015, Norway implemented cancer patient pathways to reduce waiting times for treatment. The aims of this paper were to describe patterns in waiting time and their association with patient characteristics for ...
  • Thunemann, Martin; Lu, Yichen; Liu, Xin; Kılıç, Kıvılcım; Desjardins, Michèle; Vandenberghe, Matthieu; Sadegh, Sanaz; Saisan, Payam A.; Cheng, Qun; Weldy, Kimberly L.; Lyu, Hongming; Djurovic, Srdjan; Andreassen, Ole Andreas; Dale, Anders; Devor, Anna; Kuzum, Duygu (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Recent advances in optical technologies such as multi-photon microscopy and optogenetics have revolutionized our ability to record and manipulate neuronal activity. Combining optical techniques with electrical recordings ...
  • Ligaard, Johanne; Sannæs, Julia; Pihlstrøm, Lasse (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Deep brain stimulation is offered as symptomatic treatment in advanced Parkinson’s disease, depending on a clinical assessment of the individual patient’s risk-benefit profile. Genetics contribute to phenotypic variability ...
  • Passow, Susanne; Specht, Karsten; Adamsen, Tom Christian; Biermann, Martin; Brekke, Njål; Craig-Craven, Alexander Richard; Ersland, Lars; Grüner, Renate; Kleven-Madsen, Nina; Kvernenes, Ole Heine; Schwarzlmüller, Thomas; Olesen, Rasmus Aamand; Hugdahl, Kenneth (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Over the last decade, the brain's default-mode network (DMN) and its function has attracted a lot of attention in the field of neuroscience. However, the exact underlying mechanisms of DMN functional connectivity, or more ...