Now showing items 1738-1757 of 7899

  • Rinde, Fridtjof Balteskard; Frønæs, Synne Grønvold; Ghanima, Waleed Khalid; Vik, Anders; Hansen, John-Bjarne; Brækkan, Sigrid (Journal article / Tidsskriftartikkel / SubmittedVersion, 2020)
    Background Current guidelines recommend the use of clinical decision rules, such as Wells score, in combination with D-dimer to assess the need for objective imaging to rule out deep vein thrombosis (DVT). However, the ...
  • Bonsaksen, Tore; Heir, Trond; Skogstad, Laila; Grimholt, Tine K.; Ekeberg, Øivind; Lerdal, Anners; Schou-Bredal, Inger (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
    Purpose Harmful use of alcohol is a major public health problem. While harm is often researched in the context of heavy drinking episodes, high-frequency drinking, even when drinking moderate quantities, constitutes a ...
  • Lagali, Neil S.; Allgeier, Stephan; Guimarães, Pedro; Badian, Reza; Ruggeri, Alfredo; Köhler, Bernd; Utheim, Tor Paaske; Peebo, Beatrice; Peterson, Magnus; Dahlin, Lars B.; Rolandsson, Olov (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    A dense nerve plexus in the clear outer window of the eye, the cornea, can be imaged in vivo to enable non-invasive monitoring of peripheral nerve degeneration in diabetes. However, a limited field of view of corneal nerves, ...
  • Campo, Giuseppe; Pavasini, Rita; Morciano, Giampaolo; Lincoff, Michael A; C Gibson, Michael; Kitakaze, Masafumi; Lonborg, Jacob; Ahluwalia, Amrita; Ishii, Hideki; Frenneaux, Michael; Ovize, Michel; Galvani, Marcello; Atar, Dan; Ibanez, Berta; Cerisano, Giampaolo; Biscaglia, Simone; Neil, Brandon J; Asakura, Masanori; Engstrom, Thomas; Jones, Daniel A; Dawson, Dana; Ferrari, Roberto; Pinton, Paolo; Ottani, Filippo (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Mortality and morbidity in patients with ST elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) are still high [1]. A huge amount of the myocardial damage is related to the ...
  • Dannenfelser, Ruth; Nome, Marianne Eikhom; Tahiri, Andliena; Ursini-Siegel, Josie; Vollan, Hans Kristian Moen; Haakensen, Vilde Drageset; Helland, Åslaug; Naume, Bjørn; Caldas, Carlos; Børresen-Dale, Anne-Lise; Kristensen, Vessela N.; Troyanskaya, Olga G. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    The tumor microenvironment is now widely recognized for its role in tumor progression, treatment response, and clinical outcome. The intratumoral immunological landscape, in particular, has been shown to exert both ...
  • Verbeke, Caroline Sophie; Webster, Fleur; Brosens, Lodewijk; Campbell, Fiona M.; Del Chiaro, Marco; Esposito, Irene; Feakins, Roger M.; Fukushima, Noriyoshi; Gill, Anthony J.; Kakar, Sanjay; Kench, James G.; Krasinskas, Alyssa M.; Van Laethem, Jean-Luc; Schaeffer, David F.; Washington, Kay (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Aims Current guidelines for pathology reporting on pancreatic cancer differ in certain aspects, resulting in divergent reporting practices and a lack of comparability of data. Here, we report on a new international ...
  • Simonsen, Trude Golimo; Lund, Kjersti Vassmo; Hompland, Tord; Kristensen, Gunnar S Balle; Rofstad, Einar K (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Purpose: The poor outcome of locally advanced cervical cancer has been associated with extensive hypoxia and high interstitial fluid pressure (IFP) in the primary tumor. In the present study, measures of tumor hypoxia and ...
  • Henriksen, Mari W; Ravn, Kirstine; Paus, Benedicte; von Tetzchner, Stephen; Skjeldal, Ola H (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background Rett syndrome (RTT) is a neurodevelopmental disorder. In more than 95% of females with classic RTT a pathogenic mutation in MECP2 has been identified. This leaves a small fraction of classic cases ...
  • Angell, Inga Leena; Nilsen, Morten; Carlsen, Karin C. Lødrup; Carlsen, Kai-Håkon; Hedlin, Gunilla; Jonassen, Christine M; Marsland, Benjamin; Nordlund, Björn; Rehbinder, Eva Maria; Schinagl, Carina Madelen; Skjerven, Håvard Ove; Staff, Anne Cathrine; Söderhäll, Cilla; Vettukattil, Muhammad Riyas; Rudi, Knut (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Nanopore sequencing is rapidly becoming more popular for use in various microbiota-based applications. Major limitations of current approaches are that they do not enable de novo species identification and that they cannot ...
  • Moosavi, Seyed H.; Eide, Peter W.; Eilertsen, Ina A.; Brunsell, Tuva H.; Berg, Kaja C. G.; Røsok, Bård I.; Brudvik, Kristoffer W.; Bjørnbeth, Bjørn A.; Guren, Marianne G.; Nesbakken, Arild; Lothe, Ragnhild A.; Sveen, Anita (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background Gene expression-based subtyping has the potential to form a new paradigm for stratified treatment of colorectal cancer. However, current frameworks are based on the transcriptomic profiles of ...
  • Davidson, Ben; McFadden, Erin; Holth, Arild; Brunetti, Marta; Flørenes, Vivi Ann (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract The objective of this study was to analyze the expression and clinical role of mitosis regulators α-thalassemia/mental retardation syndrome X-linked (ATRX) and death-domain-associated protein (DAXX) in metastatic ...
  • Bøylestad, Lillian; Stray-Pedersen, Arne; Vege, Åshild; Osberg, Silje; Rognum, Torleiv Ole (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
    Aim This study reviewed cases of sudden unexpected child deaths in Norway to determine the significance of death‐scene investigations (DSIs) in establishing cause and manner of death, and thereby it is relevance to legal ...
  • Kjekshus, John (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2001)
    Treatment to prevent progression of heart failure has been targeted to reverse the consequences of heart failure and to a lesser extent the cause – the atherosclerotic plaque itself. Less than 50% of patients with heart ...
  • Bjørshol, Conrad A; Sunde, Kjetil; Myklebust, Helge; Assmus, Jörg; Søreide, Eldar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background The aim of this study was to measure chest compression decay during simulated advanced life support (ALS) in a cardiac arrest manikin model. Methods ...
  • Fosheim, Ingrid Knutsdotter; Johnsen, G.M.; Alnaes-Katjavivi, P.; Turowski, Gitta Erika; Sugulle, M.; Staff, A.C. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Introduction Uteroplacental acute atherosis is frequently observed in preeclampsia, and shares features with early atherosclerotic lesions, including artery wall foam cells. The lipid-associated proteins FABP4 (fatty ...
  • Alnæs-Katjavivi, Patji Haakon (Doctoral thesis / Doktoravhandling, 2020)
    Preeclampsia, a hypertensive disease of pregnancy, impacts on both mother and child health during pregnancy, and adds to the mother’s risk of developing atherosclerotic cardiovascular disease later in life. Underlying ...
  • Bergholtz, Helga (Doctoral thesis / Doktoravhandling, 2020)
    Breast cancer affects over 3500 women in Norway every year. Since the introduction of mammographic screening, early stage breast cancers are diagnosed more frequently and many of these are non-invasive with low potential ...
  • Cassetta, Luca; Bækkevold, Espen Sønderaal; Brandau, Sven; Bujko, Anna; Cassatella, Marco A.; Dorhoi, Anca; Krieg, Carsten; Lin, Ang; Loré, Karin; Marini, Olivia; Pollard, Jeffrey W.; Roussel, Mikael; Scapini, Patrizia; Umansky, Viktor; Adema, Gosse J. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    In cancer, infection and inflammation, the immune system’s function can be dysregulated. Instead of fighting disease, immune cells may increase pathology and suppress host-protective immune responses. Myeloid cells show ...
  • Pfefferle, Aline; Jacobs, Benedikt Marcel; Haroun-Izquierdo, Alvaro; Kveberg, Lise; Sohlberg, Ebba; Malmberg, Karl-Johan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Natural killer (NK) cells have a central role within the innate immune system, eliminating virally infected, foreign and transformed cells through their natural cytotoxic capacity. Release of their cytotoxic granules is ...
  • Boer, Cindy G.; Hatzikotoulas, Konstantinos; Southam, Lorraine; Stefánsdóttir, Lilja; Almeida, Rodrigo Coutinho de; Zhang, Yanfei; Wu, Tian T.; Zheng, Jie; Hartley, April; Teder-Laving, Maris; Skogholt, Anne Heidi; Terao, Chikashi; Zengini, Eleni; Alexiadis, George; Barysenka, Andrei; Bjornsdottir, Gyda; Gabrielsen, Maiken Elvestad; Gilly, Arthur; Ingvarsson, Thorvaldur; Johnsen, Marianne Bakke; Jonsson, Helgi; Kloppenburg, Margreet; Luetge, Almut; Lund, Sigrun H; Magi, Reedik; Mangino, Massimo; Nelissen, Rob G.H.H.; Shivakumar, Manu; Steinberg, Julia; Takuwa, Hiroshi; Thomas, Laurent; Tuerlings, Margo; Babis, George C.; Cheung, Jason Pui Yin; Kang, Jae Hee; Kraft, Peter; Lietman, Steven A.; Samartzis, Dino; Slagboom, P. Eline; Stefansson, Kari; Thorsteinsdottir, Unnur; Tobias, Jonathan H.; Uitterlinden, André G.; Winsvold, Bendik K S; Zwart, John Anker Henrik; Smith, George Davey; Sham, Pak Chung; Thorleifsson, Gudmar; Hveem, Kristian; Zeggini, Eleftheria (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and identify 100 independently associated ...