Now showing items 1857-1876 of 4274

  • Roessler, Kirsten K; Muller, Ashley E (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background Women who exercise intensively, whether competitive or recreational, devote a lot of time and energy into exercise, which requires high levels of ambition and motivation. The aim of the study is ...
  • Piehler, Armin P. (Doctoral thesis / Doktoravhandling, 2009)
    ATP-binding cassette (ABC) transporters are integral components of most living cells and constitute a large group of structurally related transmembrane proteins. These transporters translocate a wide variety of substrates ...
  • Søberg, Kristoffer; Larsen, Anja C V; Diskar, Mandy; Backe, Paul Hoff; Bjørås, Magnar; Jahnsen, Tore; Lærdahl, Jon Kristen; Rognes, Torbjørn; Herberg, Friedrich W.; Skålhegg, Bjørn Steen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    The genes PRKACA and PRKACB encode the principal catalytic (C) subunits of protein kinase A (PKA) Cα and Cβ, respectively. Cα is expressed in all eukaryotic tissues examined and studies of Cα knockout mice demonstrate a ...
  • Berge, Elisabet O; Knappskog, Stian; Geisler, Stephanie; Staalesen, Vidar; Pacal, Marec; Børresen-Dale, Anne-Lise; Puntervoll, Pål; Lillehaug, Johan R; Lønning, Per E (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)
    Background The tumor suppressor pRb plays a key role regulating cell cycle arrest, and disturbances in the RB1 gene have been reported in different cancer forms. However, the literature reports contradictory ...
  • Andresen, Henriette; Moltzau, Lise R; Fagerheim, Steffen; Gloriam, David; Bach, Trond; Levy, Finn O (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
  • Braathen, Ranveig; Sandvik, Anders; Berntzen, Gøril; Hammerschmidt, S; Fleckenstein, Burkhard; Sandlie, Inger; Brandtzæg, Per; Johansen, Finn Eirik; Lauvrak, Vigdis (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)
    The polymeric Ig receptor (pIgR), also called membrane secretory component (SC), mediates epithelial transcytosis of polymeric immunoglobulins (pIgs). J Chain-containing polymeric IgA (pIgA) and pentameric IgM bind pIgR ...
  • Brunetti, Marta; Gorunova, Ludmila; Davidson, Ben; Heim, Sverre; Panagopoulos, Ioannis; Micci, Francesca (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Recurrent chromosomal translocations leading to gene fusion formation have been described in uterine sarcomas, including low-grade endometrial stromal sarcoma (LG-ESS). Involvement of the PHF1 gene in chromosomal rearrangements ...
  • Lind, Guro E; Danielsen, Stine A; Ahlquist, Terje; Merok, Marianne A; Andresen, Kim; Skotheim, Rolf I; Hektoen, Merete; Rognum, Torleiv O; Meling, Gunn I; Hoff, Geir; Bretthauer, Michael; Thiis-Evensen, Espen; Nesbakken, Arild; Lothe, Ragnhild A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background The presence of cancer-specific DNA methylation patterns in epithelial colorectal cells in human feces provides the prospect of a simple, non-invasive screening test for colorectal cancer and its ...
  • Samarakoon, Pubudu S; Sorte, Hanne S; Kristiansen, Bjørn E; Skodje, Tove; Sheng, Ying; Tjønnfjord, Geir E; Stadheim, Barbro; Stray-Pedersen, Asbjørg; Rødningen, Olaug K; Lyle, Robert (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
    Background With advances in next generation sequencing technologies and genomic capture techniques, exome sequencing has become a cost-effective approach for mutation detection in genetic diseases. However, ...
  • Navaratnam, Jesintha; Dedi, Lumnije; Tjølsen, Andreas Myklebust; Bragadottir, Ragnheidur (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    To the best of our knowledge, we report the first case of Dietzia species in a patient with endophthalmitis. A 47-year-old man presented to the ophthalmology department with decreased vision, redness, and minimal pain in ...
  • Austbø, Lars; Kampmann, Andreas; Müller-Ladner, Ulf; Neumann, Elena; Olsaker, Ingrid; Skretting, Grethe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)
    Backgound In scrapie and prion diseases, the knowledge concerning genes involved in host response during the early infection period in the lymphoid tissues, still remains limited. In the present study, we ...
  • Impellizzeri, Agata Antonina Rita; Pappalardo, Matteo; Basile, Livia; Manfra, Ornella; Andressen, Kjetil Wessel; Krobert, Kurt Allen; Messina, Angela; Levy, Finn Olav; Guccione, Salvatore (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    The human 5-HT7 receptor is expressed in both the central nervous system and peripheral tissues and is a potential drug target in behavioral and psychiatric disorders. We examined molecular determinants of ligand binding ...
  • Edgren, Henrik; Murumagi, Astrid; Kangaspeska, Sara; Nicorici, Daniel; Hongisto, Vesa; Kleivi, Kristine; Rye, Inga H; Nyberg, Sandra; Wolf, Maija; Borresen-Dale, Anne-Lise; Kallioniemi, Olli (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background Until recently, chromosomal translocations and fusion genes have been an underappreciated class of mutations in solid tumors. Next-generation sequencing technologies provide an opportunity for ...
  • Smeland, Olav Bjerkehagen; Frei, Oleksandr; Kauppi, Karolina; Hill, W. David; Li, Wen; Wang, Yunpeng; Krull, Florian; Bettella, Francesco; Eriksen, Jon Alm; Witoelar, Aree; Davies, Gail; Fan, Chun Chieh; Thompson, Wesley Kurt; Lam, Max; Lencz, Todd; Chen, Chi-Hua; Ueland, Torill; Jönsson, Erik Gunnar; Djurovic, Srdjan; Deary, Ian J.; Dale, Anders; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Importance: Schizophrenia is associated with widespread cognitive impairments. Although cognitive deficits are one of the factors most strongly associated with functional outcome in schizophrenia, current treatment strategies ...
  • O`Connell, Kevin; Shadrin, Alexey A.; Smeland, Olav Bjerkehagen; Bahrami, Shahram; Frei, Oleksandr; Bettella, Francesco; Krull, Florian; Fan, Chun C.; Askeland, Ragna Bugge; Knudsen, Gun Peggy Strømstad; Halmøy, Anne; Steen, Nils Eiel; Ueland, Torill; Walters, Bragi; Davíðsdóttir, Katrín; Haraldsdóttir, Gyda S.; Guðmundsson, Ólafur; Stefansson, Hreinn; Reichborn-Kjennerud, Ted; Haavik, Jan; Dale, Anders M.; Stefánsson, Kári; Djurovic, Srdjan; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Background Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that is consistently associated with lower levels of educational attainment. A recent large genome-wide association study identified ...
  • Smeland, Olav Bjerkehagen; Wang, Yunpeng; Lo, Min-Tzu; Li, Wen; Frei, Oleksandr; Witoelar, Aree; Tesli, Martin Steen; Hinds, David A.; Tung, Joyce Y.; Djurovic, Srdjan; Chen, Chi-Hua; Dale, Anders; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Schizophrenia is associated with differences in personality traits, and recent studies suggest that personality traits and schizophrenia share a genetic basis. Here we aimed to identify specific genetic loci shared between ...
  • O`Connell, Kevin; Shadrin, Alexey A.; Bahrami, Shahram; Smeland, Olav Bjerkehagen; Bettella, Francesco; Frei, Oleksandr; Krull, Florian; Askeland, Ragna Bugge; Walters, Bragi; Davíðsdóttir, Katrín; Haraldsdóttir, Gyða; Guðmundsson, Ólafur; Stefánsson, Hreinn; Fan, Chun C.; Steen, Nils Eiel; Reichborn-Kjennerud, Ted; Dale, Anders; Stefánsson, Kári; Djurovic, Srdjan; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Differential diagnosis between childhood onset attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder (BD) remains a challenge, mainly due to overlapping symptoms and high rates of comorbidity. Despite this, ...
  • Halvorsen, Ann Rita; Aure, Miriam Ragle; Øjlert, Åsa Kristine; Brustugun, Odd Terje; Solberg, Steinar; Nebdal, Daniel; Helland, Åslaug (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Dysregulation of microRNAs is a common mechanism in the development of lung cancer, but the relationship between microRNAs and expression subtypes in non‐small‐cell lung cancer (NSCLC) is poorly explored. Here, we analyzed ...
  • O'Mara, Tracy A.; Glubb, Dylan M.; Amant, Frédéric; Annibali, Daniela; Ashton, Katie; Attia, John; Auer, Paul L.; Beckmann, Matthias W.; Black, Amanda; Bolla, Manjeet K.; Brauch, Hiltrud; Brenner, Hermann; Brinton, Louise; Buchanan, Daniel D.; Burwinkel, Barbara; Chang-Claude, Jenny; Chanock, Stephen J.; Chen, Chu; Chen, Maxine M.; Cheng, Timothy H.T.; Clarke, Christine L.; Clendenning, Mark; Cook, Linda S.; Couch, Fergus J.; Cox, Angela; Crous-Bous, Marta; Czene, Kamila; Day, Felix; Dennis, Joe; Depreeuw, Jeroen; Doherty, Jennifer Anne; Dörk, Thilo; Dowdy, Sean C.; Dürst, Matthias; Ekici, Arif B.; Fasching, Peter A.; Fridley, Brooke L.; Friedenreich, Christine M.; Fritschi, Lin; Fung, Jenny; García-Closas, Montserrat; Gaudet, Mia M.; Giles, Graham G.; Goode, Ellen L.; Gorman, Maggie; Haiman, Christopher A.; Hall, Per; Hankison, Susan E.; Healey, Catherine S.; Hein, Alexander; Hillemanns, Peter; Hodgson, Shirley; Høivik, Erling Andre; Holliday, Elizabeth G.; Hopper, John L.; Hunter, David J.; Jones, Angela; Krakstad, Camilla; Kristensen, Vessela N.; Lambrechts, Diether; Marchand, Loic Le; Liang, Xiaolin; Lindblom, Annika; Lissowska, Jolanta; Long, Jirong; Lu, Lingeng; Magliocco, Anthony M.; Martin, Lynn; McEvoy, Mark; Meindl, Alfons; Michailidou, Kyriaki; Milne, Roger L.; Mints, Miriam; Montgomery, Grant W.; Nassir, Rami; Olsson, Håkan; Orlow, Irene; Otton, Geoffrey; Palles, Claire; Perry, John R.B.; Peto, Julian; Pooler, Loreall; Prescott, Jennifer; Proietto, Tony; Rebbeck, Timothy R.; Risch, Harvey A.; Rogers, Peter A.W.; Rübner, Matthias; Runnebaum, Ingo; Sacerdote, Carlotta; Sarto, Gloria E.; Schumacher, Fredrick; Scott, Rodney J.; Setiawan, V. Wendy; Shah, Mitul; Sheng, Xin; Shu, Xiao-Ou; Southey, Melissa C.; Swerdlow, Anthony J.; Tham, Emma; Trovik, Jone; Turman, Constance; Tyrer, Jonathan P.; Vachon, Celine; VanDen Berg, David; Vanderstichele, Adriaan; Wang, Zhaoming; Webb, Penelope M.; Wentzensen, Nicolas; Werner, Henrica Maria Johanna; Winham, Stacey J.; Wolk, Alicja; Xia, Lucy; Xiang, Yong-Bing; Yang, Hannah P.; Yu, Herbert; Zheng, Wei; Pharoah, Paul D.P.; Dunning, Alison M.; Kraft, Peter; De Vivo, Immaculata; Tomlinson, Ian; Easton, Douglas F.; Spurdle, Amanda B.; Thompson, Deborah J. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Endometrial cancer is the most commonly diagnosed cancer of the female reproductive tract in developed countries. Through genome-wide association studies (GWAS), we have previously identified eight risk loci for endometrial ...
  • Agostini, Antonio; Brunetti, Marta; Davidson, Ben; Tropé, Claes Gøran; Heim, Sverre; Panagopoulos, Ioannis; Micci, Francesca (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)