Browsing Institutt for klinisk medisin by Title
Now showing items 3151-3170 of 3558
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)Background Activated leukocytes may contribute to the development and progression of heart failure (HF). We investigated the predictive value of circulating levels of stable and readily detectable markers reflecting ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2001)Type-B T cells raised against the immunodominant peptide in hen egg lysozyme (HEL(48-62)) do not respond to whole lysozyme, and this has been thought to indicate that peptide can bind to I-A(k) in different conformations. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Mycobacterium tuberculosis (Mtb) is particularly challenging for the immune system being an intracellular pathogen, and a variety of T cell subpopulations are activated by the host defence mechanism. In this study, we ...
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(Doctoral thesis / Doktoravhandling, 2017)
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T2 weighted MRI and Histopathology as Markers for Response to Somatostatin Analogues in Acromegaly (Doctoral thesis / Doktoravhandling, 2016)
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)Background: The tapering of methadone or buprenorphine during pregnancy is an understudied and controversial issue. The aim of this study was to determine to what extent women tapered their opioid medication dose during ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)The quantification of illicit drug and pharmaceutical residues in sewage has been shown to be a valuable tool that complements existing approaches in monitoring the patterns and trends of drug use. The present work delineates ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background Therapeutic idiotypic (Id) vaccination is an experimental treatment for selected B cell malignancies. A broader use of Id-based vaccination, however, is hampered by the complexity and costs due ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background: Idiotypes (Id) are antigenic determinants localized in variable (V) regions of Ig. Id-specific T and B cells (antibodies) play a role in immunotherapy of Id+ tumors. However, vaccine strategies that enhance ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Hereditary ataxia and spastic paraplegia are heterogeneous monogenic neurodegenerative disorders. To date, a large number of individuals with such disorders remain undiagnosed. Here, we have assessed molecular diagnosis ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)Objective To determine the effectiveness of the Targeted Interdisciplinary Model for Evaluation and Treatment of Neuropsychiatric Symptoms (TIME) for treatment of moderate to severe agitation in people with dementia. Methods ...
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(Doctoral thesis / Doktoravhandling, 2017)
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(Doctoral thesis / Doktoravhandling, 2017)The complement system is part of the immediate innate immune response to pending danger. However, uncontrolled activation contributes to the pathophysiology of many human diseases. Complement inhibitory therapy is approved ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Human regulatory T cells (Tregs) are essential in maintaining immunological tolerance and suppress effector T cells. Tregs are commonly up-regulated in chronic infectious diseases such as tuberculosis (TB) and human ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Rab GTPases are key regulators of intracellular trafficking, and cycle between a GTP-bound active state and a GDP-bound inactive state. This cycle is regulated by guanine-nucleotide exchange factors (GEFs) and GTPase-activating ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2016)CD4+ T cells recognizing dietary gluten epitopes in the context of disease-associated human leukocyte antigen (HLA)-DQ2 or HLA-DQ8 molecules are the key players in celiac disease pathogenesis. Here, we conducted a large-scale ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Selection of biased T cell receptor (TCR) repertoires across individuals is seen in both infectious diseases and autoimmunity, but the underlying molecular basis leading to these shared repertoires remains unclear. Celiac ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)TCTP has been implicated in a plethora of important cellular processes related to cell growth, cell cycle progression, malignant transformation and inhibition of apoptosis. In addition to these intracellular functions, ...
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(Doctoral thesis / Doktoravhandling, 2010)Skulderplager er et økende problem i dagens samfunn. Arbeidsstillinger med langvarig, ensidig skulderbelastning, og et ønske om høy aktivitet hos mange eldre, kan ha bidratt til dette. Plagene er ofte relatert til en skade ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Objectives: To find and discuss what has been published about the use of telehealth, on people with spinal cord injury (teleSCI). Method: Cochrane Library, Ovid Medline, EMBASE and CINAHL, from 1996 till June 2017 have ...