Browsing Institutt for klinisk medisin by Title
Now showing items 2226-2245 of 2518
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2001)Type-B T cells raised against the immunodominant peptide in hen egg lysozyme (HEL(48-62)) do not respond to whole lysozyme, and this has been thought to indicate that peptide can bind to I-A(k) in different conformations. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Mycobacterium tuberculosis (Mtb) is particularly challenging for the immune system being an intracellular pathogen, and a variety of T cell subpopulations are activated by the host defence mechanism. In this study, we ...
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(Doctoral thesis / Doktoravhandling, 2017)
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T2 weighted MRI and Histopathology as Markers for Response to Somatostatin Analogues in Acromegaly (Doctoral thesis / Doktoravhandling, 2016)
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)Background: The tapering of methadone or buprenorphine during pregnancy is an understudied and controversial issue. The aim of this study was to determine to what extent women tapered their opioid medication dose during ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background Therapeutic idiotypic (Id) vaccination is an experimental treatment for selected B cell malignancies. A broader use of Id-based vaccination, however, is hampered by the complexity and costs due ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background: Idiotypes (Id) are antigenic determinants localized in variable (V) regions of Ig. Id-specific T and B cells (antibodies) play a role in immunotherapy of Id+ tumors. However, vaccine strategies that enhance ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Hereditary ataxia and spastic paraplegia are heterogeneous monogenic neurodegenerative disorders. To date, a large number of individuals with such disorders remain undiagnosed. Here, we have assessed molecular diagnosis ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)Objective To determine the effectiveness of the Targeted Interdisciplinary Model for Evaluation and Treatment of Neuropsychiatric Symptoms (TIME) for treatment of moderate to severe agitation in people with dementia. Methods ...
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(Doctoral thesis / Doktoravhandling, 2017)
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(Doctoral thesis / Doktoravhandling, 2017)The complement system is part of the immediate innate immune response to pending danger. However, uncontrolled activation contributes to the pathophysiology of many human diseases. Complement inhibitory therapy is approved ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Human regulatory T cells (Tregs) are essential in maintaining immunological tolerance and suppress effector T cells. Tregs are commonly up-regulated in chronic infectious diseases such as tuberculosis (TB) and human ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2016)CD4+ T cells recognizing dietary gluten epitopes in the context of disease-associated human leukocyte antigen (HLA)-DQ2 or HLA-DQ8 molecules are the key players in celiac disease pathogenesis. Here, we conducted a large-scale ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Selection of biased T cell receptor (TCR) repertoires across individuals is seen in both infectious diseases and autoimmunity, but the underlying molecular basis leading to these shared repertoires remains unclear. Celiac ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)TCTP has been implicated in a plethora of important cellular processes related to cell growth, cell cycle progression, malignant transformation and inhibition of apoptosis. In addition to these intracellular functions, ...
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(Doctoral thesis / Doktoravhandling, 2010)Skulderplager er et økende problem i dagens samfunn. Arbeidsstillinger med langvarig, ensidig skulderbelastning, og et ønske om høy aktivitet hos mange eldre, kan ha bidratt til dette. Plagene er ofte relatert til en skade ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background The Cochrane review on the effectiveness of speech and language therapy for aphasia following stroke suggests intensity of therapy is a key predictor for outcome. Current aphasia services cannot ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background Ulcerative colitis (UC) is a chronic, inflammatory bowel disease which may lead to dysplasia and adenocarcinoma in patients when long-lasting. Short telomeres have been reported in mucosal cells ...
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(Doctoral thesis / Doktoravhandling, 2011)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship ...