Browsing Institutt for klinisk medisin by Title
Now showing items 2054-2073 of 5596
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(Doctoral thesis / Doktoravhandling, 2019)G protein-coupled receptors (GPCRs) constitute a large group of proteins involved in conveying extracellular signals to the inside of the cell. There are different classes of GPCRs, which can be activated by different ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)We have previously shown that plasmablasts of the G1m1 allotype of IgG1 areselectively enriched in the cerebrospinal fluid of G1m1/G1m3 heterozygouspatients with multiple sclerosis, whereas both allotypes are equally used ...
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(Doctoral thesis / Doktoravhandling, 2020)Many individuals with Parkinson’s disease (PD), a degenerative neurological disorder affecting the basal ganglia, experience disturbances of postural control and gait. Structured exercise is an integral part of PD-management, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Objective: Marine polyunsaturated n-3 fatty acids (n-3 PUFA) may have cardioprotective effects and beneficial influence on the fibrotic process. We evaluated the associations between serum marine n-3 PUFA and selected ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)The role of surgery in the management of metastatic gastric cancer (MGC) remains unclear. The aim of this study was to investigate the surgical and oncologic outcomes of gastrectomy in patients with MGC. The study included ...
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Gastric bypass surgery has a weight-loss independent effect on post-challenge serum glucose levels (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background Gastric bypass surgery seems to have an effect on glucose metabolism beyond what is mediated through weight reduction. The magnitude of this effect on fasting and post-challenge glucose levels ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2020)Aims Morbid obesity is a risk factor for cardiovascular disease. The relative effects of Roux-en-Y gastric bypass surgery (GBS) and intensive lifestyle intervention (ILI) on subclinical myocardial injury, the activity ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Background For patients with obesity and type 2 diabetes, weight loss improves insulin sensitivity and β-cell function, and can induce remission of diabetes. The comparative efficacy of various bariatric procedures for ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Background Sleeve gastrectomy, with its short operating time, is possible to perform as same-day surgery, with the most common reason for requiring overnight hospital stay being postoperative nausea and vomiting. Objective To ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)Background Between November 2 and 10, 2002 several patients with psoriasis and personnel staying in the health centre in Gran Canaria, Spain fell ill with diarrhoea, vomiting or both. Patient original came ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Objectives Acute upper gastrointestinal bleeding is a well-recognized complication of peptic ulcers and erosions. The aim of this study was to assess the incidence rate and identify risk factors for this complication ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)The majority of research studies in systemic sclerosis focus largely on addressing skin and cardiopulmonary manifestations. Fewer studies assess the pathogenesis and treatment of gastrointestinal tract involvement in ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background The study aimed to assess whether gastrointestinal (GI) symptoms at admission are associated with increased short-term mortality in patients with invasive pneumococcal disease (IPD). ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background In early-phase studies with targeted therapeutics and radiotherapy, it may be difficult to decide whether an adverse event should be considered a dose-limiting toxicity (DLT) of the investigational ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Mucosal pathology due to chronic mesenteric ischemia (CMI) is rarely seen during upper endoscopy. Combining Laser Doppler Flowmetry (LDF) and Visible Light Spectroscopy (VLS) may aid in detection of CMI at an early stage. We ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. Here we ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)Objective: Coding variants in the GBA gene have been identified as the numerically most important genetic risk factors for Parkinson's disease (PD). In addition, genome-wide association studies (GWAS) have identified ...
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(Doctoral thesis / Doktoravhandling, 2007)Successful kidney transplantation is the best treatment for patients with end stage renal disease and graft survival is one of the most important measures of success in kidney transplantation. The majority of the patients ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Infarct evolution rate and response to acute reperfusion therapy may differ between patients, which is important to consider for accurate management and treatment of patients with ST-elevation ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background Gender differences in short-term mortality in acute myocardial infarction (AMI) have been studied extensively, whereas gender differences in long-term mortality and cause of death largely remain ...