Browsing Institutt for klinisk medisin by Title

Now showing items 2216-2235 of 6055

  • G protein coupling and signaling of Gs-coupled serotonin receptors 
    Ulsund, Andrea Hembre (Doctoral thesis / Doktoravhandling, 2019)
    G protein-coupled receptors (GPCRs) constitute a large group of proteins involved in conveying extracellular signals to the inside of the cell. There are different classes of GPCRs, which can be activated by different ...
  • G1m1 predominance of intrathecal virus-specific antibodies in multiple sclerosis 
    Tomescu-Baciu, Alina; Vartdal, Frode; Holmøy, Trygve; Vedeler, Christian A.; Lossius, Peter Andreas Vold (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    We have previously shown that plasmablasts of the G1m1 allotype of IgG1 areselectively enriched in the cerebrospinal fluid of G1m1/G1m3 heterozygouspatients with multiple sclerosis, whereas both allotypes are equally used ...
  • Gait and gait variability in individuals with Parkinson’s disease: validity, reliability and long-term effects of intensive balance and gait training 
    Rennie, Linda (Doctoral thesis / Doktoravhandling, 2020)
    Many individuals with Parkinson’s disease (PD), a degenerative neurological disorder affecting the basal ganglia, experience disturbances of postural control and gait. Structured exercise is an integral part of PD-management, ...
  • Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency 
    Freitag, Nancy; Tirado-Gonzalez, Irene; Barrientos, Gabriela; Powell, Katie L.; Boehm-Sturm, Philipp; Koch, Stefan P.; Hecher, Kurt; Staff, Anne Cathrine; Arck, Petra Clara; Diemert, Anke; Blois, Sandra M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Fetal growth restriction (FGR) is the most common pregnancy complication in developed countries. Pregnancies affected by FGR, frequently concur with complications and high risk of neonatal morbidity and mortality. To date, ...
  • Galectin-3, a marker of cardiac remodeling, is inversely related to serum Levels of marine omega-3 fatty acids. A cross-sectional study 
    Laake, K; Seljeflot, Ingebjørg; Schmidt, EB; Myhre, Peder Langeland; Tveit, Arnljot; Nordseth, Jon; Arnesen, Harald; Solheim, Svein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Objective: Marine polyunsaturated n-3 fatty acids (n-3 PUFA) may have cardioprotective effects and beneficial influence on the fibrotic process. We evaluated the associations between serum marine n-3 PUFA and selected ...
  • Gastrectomy for metastatic gastric cancer: a 15-year experience from a developing country 
    Sahakyan, Mushegh; Gabrielyan, Artak; Aghayan, Davit; Yesayan, Shushan; Petrosyan, Hmayak; Chobanyan, Alina; Kazaryan, Airazat M.; Sahakyan, Artur M. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    The role of surgery in the management of metastatic gastric cancer (MGC) remains unclear. The aim of this study was to investigate the surgical and oncologic outcomes of gastrectomy in patients with MGC. The study included ...
  • Gastric bypass surgery has a weight-loss independent effect on post-challenge serum glucose levels 
    Hofsø, Dag; Birkeland, Kåre I; Holst, Jens J; Bollerslev, Jens; Sandbu, Rune; Røislien, Jo; Hjelmesæth, Jøran (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background Gastric bypass surgery seems to have an effect on glucose metabolism beyond what is mediated through weight reduction. The magnitude of this effect on fasting and post-challenge glucose levels ...
  • Gastric bypass surgery is associated with reduced subclinical myocardial injury and greater activation of the cardiac natriuretic peptide system than lifestyle intervention 
    Aakre, Kristin Moberg; Omland, Torbjørn; Nordstrand, Njord; Gjevestad, Espen Svendsen; Holven, Kirsten Bjørklund; Lyngbakken, Magnus; Hjelmesæth, Jøran (Journal article / Tidsskriftartikkel / SubmittedVersion, 2020)
    Aims Morbid obesity is a risk factor for cardiovascular disease. The relative effects of Roux-en-Y gastric bypass surgery (GBS) and intensive lifestyle intervention (ILI) on subclinical myocardial injury, the activity ...
  • Gastric bypass versus sleeve gastrectomy in patients with type 2 diabetes (Oseberg): a single-centre, triple-blind, randomised controlled trial 
    Hofsø, Dag; Fatima, Farhat; Borgeraas, Heidi; Birkeland, Kåre I.; Gulseth, Hanne Løvdal; Hertel, Jens Kristoffer; Johnson, Line Kristin; Lindberg, Morten; Nordstrand, Njord; Småstuen, Milada Cvancarova; Stefanovski, Darko; Svanevik, Marius; Valderhaug, Tone Gretland; Sandbu, Rune; Hjelmesæth, Jøran (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Background For patients with obesity and type 2 diabetes, weight loss improves insulin sensitivity and β-cell function, and can induce remission of diabetes. The comparative efficacy of various bariatric procedures for ...
  • Gastric sleeve resection as day-case surgery: what affects the discharge time? 
    Aftab, Hira; Fagerland, Morten; Gondal, Ghous; Ghanima, Waleed Khalid; Olsen, Magnus Kringstad; Nordby, Tom (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Background Sleeve gastrectomy, with its short operating time, is possible to perform as same-day surgery, with the most common reason for requiring overnight hospital stay being postoperative nausea and vomiting. Objective To ...
  • Gastro-enteritis outbreak among Nordic patients with psoriasis in a health centre in Gran Canaria, Spain: a cohort study 
    Eriksen, Hanne M; Guerin, Philippe J; Nygård, Karin; Hjertqvist, Marika; de Jong, Birgitta; Rose, Angela M; Kuusi, Markku; Durr, Ulrike; Rojas, AG; Mør, Cato; Aavitsland, Preben (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)
    Background Between November 2 and 10, 2002 several patients with psoriasis and personnel staying in the health centre in Gran Canaria, Spain fell ill with diarrhoea, vomiting or both. Patient original came ...
  • Gastrointestinal bleeding due to peptic ulcers and erosions - a prospective observational study (BLUE study) 
    Romstad, Kartine Maria Kauczynska; Detlie, Trond Espen; Søberg, Taran; Ricanek, Petr; Jahnsen, Marte Eide; Lerang, Frode; Jahnsen, Jørgen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Objectives Acute upper gastrointestinal bleeding is a well-recognized complication of peptic ulcers and erosions. The aim of this study was to assess the incidence rate and identify risk factors for this complication ...
  • Gastrointestinal involvement in systemic sclerosis: Effects on morbidity and mortality and new therapeutic approaches 
    Hoffmann-Vold, Anna-Maria; Volkmann, Elizabeth R. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    The majority of research studies in systemic sclerosis focus largely on addressing skin and cardiopulmonary manifestations. Fewer studies assess the pathogenesis and treatment of gastrointestinal tract involvement in ...
  • Gastrointestinal symptoms in invasive pneumococcal disease: a cohort study 
    Floeystad, Hans K; Berild, Jacob D; Brandsaeter, Bjoern J; Vestrheim, Didrik F; Berild, Dag; Holm, Are M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background The study aimed to assess whether gastrointestinal (GI) symptoms at admission are associated with increased short-term mortality in patients with invasive pneumococcal disease (IPD). ...
  • Gastrointestinal toxicity of vorinostat: reanalysis of phase 1 study results with emphasis on dose-volume effects of pelvic radiotherapy 
    Bratland, Åse; Dueland, Svein; Hollywood, Donal; Flatmark, Kjersti; Ree, Anne H (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background In early-phase studies with targeted therapeutics and radiotherapy, it may be difficult to decide whether an adverse event should be considered a dose-limiting toxicity (DLT) of the investigational ...
  • Gastroscopy assisted laser Doppler flowmetry and visible light spectroscopy in patients with chronic mesenteric ischemia 
    Berge, Simen Tveten; Safi, Nathkai; Medhus, Asle Wilhelm; Ånonsen, Kim Vidar; Sundhagen, Jon Otto; Hisdal, Jonny; Kazmi, Syed Sajid Hussain (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Mucosal pathology due to chronic mesenteric ischemia (CMI) is rarely seen during upper endoscopy. Combining Laser Doppler Flowmetry (LDF) and Visible Light Spectroscopy (VLS) may aid in detection of CMI at an early stage. We ...
  • GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study 
    Rongve, Arvid; Witoelar, Aree; Ruiz, Agustín; Athanasiu, Lavinia; Abdelnour, Carla; Clarimon, Jordi; Heilmann-Heimbach, Stefanie; Hernández, Isabel; Moreno-Grau, Sonia; de Rojas, Itziar; Morenas-Rodríguez, Estrella; Fladby, Tormod; Sando, Sigrid Botne; Bråthen, Geir; Blanc, Frédéric; Bousiges, Olivier; Lemstra, Afina W.; van Steenoven, Inger; Londos, Elisabet; Almdahl, Ina Selseth; Pålhaugen, Lene; Eriksen, Jon Alm; Djurovic, Srdjan; Stordal, Eystein; Saltvedt, Ingvild; Ulstein, Ingun; Bettella, Francesco; Desikan, Rahul S.; Idland, Ane-Victoria; Toft, Mathias; Pihlstrøm, Lasse; Snaedal, Jon; Tárraga, Lluís; Boada, Mercè; Lleó, Alberto; Stefánsson, Hreinn; Stefánsson, Kári; Ramírez, Alfredo; Aarsland, Dag; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. Here we ...
  • The GBA variant E326K is associated with Parkinson's disease and explains a genome-wide association signal 
    Berge-Seidl, Victoria; Pihlstrøm, Lasse; Maple-Grødem, Jodi; Forsgren, Lars; Linder, Jan; Larsen, Jan Petter; Tysnes, Ole-Bjørn; Toft, Harald Mathias Strøm (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Objective: Coding variants in the GBA gene have been identified as the numerically most important genetic risk factors for Parkinson's disease (PD). In addition, genome-wide association studies (GWAS) have identified ...
  • Gender aspects in kidney transplantation 
    Øien, Cecilia M. (Doctoral thesis / Doktoravhandling, 2007)
    Successful kidney transplantation is the best treatment for patients with end stage renal disease and graft survival is one of the most important measures of success in kidney transplantation. The majority of the patients ...
  • Gender but not diabetes, hypertension or smoking affects infarct evolution in ST-elevation myocardial infarction patients – data from the CHILL-MI, MITOCARE and SOCCER trials 
    Nordlund, David; Engblom, Henrik; Bonnet, Jean-Louis; Hansen, Henrik S; Atar, Dan; Erlinge, David; Ekelund, Ulf; Heiberg, Einar; Carlsson, Marcus; Arheden, Håkan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Infarct evolution rate and response to acute reperfusion therapy may differ between patients, which is important to consider for accurate management and treatment of patients with ST-elevation ...