Browsing Institutt for klinisk medisin by Title
Now showing items 1327-1346 of 3749
-
(Doctoral thesis / Doktoravhandling, 2019)G protein-coupled receptors (GPCRs) constitute a large group of proteins involved in conveying extracellular signals to the inside of the cell. There are different classes of GPCRs, which can be activated by different ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)We have previously shown that plasmablasts of the G1m1 allotype of IgG1 areselectively enriched in the cerebrospinal fluid of G1m1/G1m3 heterozygouspatients with multiple sclerosis, whereas both allotypes are equally used ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Objective: Marine polyunsaturated n-3 fatty acids (n-3 PUFA) may have cardioprotective effects and beneficial influence on the fibrotic process. We evaluated the associations between serum marine n-3 PUFA and selected ...
-
Gastric bypass surgery has a weight-loss independent effect on post-challenge serum glucose levels (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background Gastric bypass surgery seems to have an effect on glucose metabolism beyond what is mediated through weight reduction. The magnitude of this effect on fasting and post-challenge glucose levels ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)Background Between November 2 and 10, 2002 several patients with psoriasis and personnel staying in the health centre in Gran Canaria, Spain fell ill with diarrhoea, vomiting or both. Patient original came ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background In early-phase studies with targeted therapeutics and radiotherapy, it may be difficult to decide whether an adverse event should be considered a dose-limiting toxicity (DLT) of the investigational ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. Here we ...
-
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)Objective: Coding variants in the GBA gene have been identified as the numerically most important genetic risk factors for Parkinson's disease (PD). In addition, genome-wide association studies (GWAS) have identified ...
-
(Doctoral thesis / Doktoravhandling, 2007)Successful kidney transplantation is the best treatment for patients with end stage renal disease and graft survival is one of the most important measures of success in kidney transplantation. The majority of the patients ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Infarct evolution rate and response to acute reperfusion therapy may differ between patients, which is important to consider for accurate management and treatment of patients with ST-elevation ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background Gender differences in short-term mortality in acute myocardial infarction (AMI) have been studied extensively, whereas gender differences in long-term mortality and cause of death largely remain ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Elevated serum uric acid (SUA) is associated with poor prognosis in patients with cardiovascular disease, yet it is still not decided whether the role of SUA is causal or only reflects an underlying ...
-
(Doctoral thesis / Doktoravhandling, 2010)
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background Tissue factor (TF) and its inhibitor tissue factor pathway inhibitor (TFPI) are the main regulators of the initiation of the coagulation process, important in atherothrombosis. In this study we ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background Obesity during adolescence is associated with cardiovascular mortality in adulthood. The adverse obesity-related cardiometabolic risk profile is already observed in adolescence. We aimed to examine ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Introduction The introduction of high-throughput technologies, also called -omics technologies, into epidemiology has raised the need for high-quality observational studies to reduce several sources of ...
-
(Doctoral thesis / Doktoravhandling, 2008)Follicular lymphoma (FL) represents the most common low-grade Non-Hodgkin’s lymphoma. FLs are of B cell origin, generally incurable, and frequently transform to high-grade diffuse large B cell lymphoma (DLBCL). Transformation ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Tumor size, as indicated by the T-category, is known as a strong prognostic indicator for breast cancer. It is common practice to distinguish the T1 and T2 groups at a tumor size of 2.0 cm. We investigated the 2.0-cm rule ...
-
(Doctoral thesis / Doktoravhandling, 2014)
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Breast cancers today are of predominantly T1 (0.1 ≥ 2.0 cm) or T2 (>2 ≤ 5 cm) categories due to early diagnosis. Molecular profiling using microarrays has led to the notion of breast cancer as a heterogeneous disease both ...