Browsing Institutt for klinisk medisin by Title

Now showing items 1881-1900 of 5104

  • G protein coupling and signaling of Gs-coupled serotonin receptors 
    Ulsund, Andrea Hembre (Doctoral thesis / Doktoravhandling, 2019)
    G protein-coupled receptors (GPCRs) constitute a large group of proteins involved in conveying extracellular signals to the inside of the cell. There are different classes of GPCRs, which can be activated by different ...
  • G1m1 predominance of intrathecal virus-specific antibodies in multiple sclerosis 
    Tomescu-Baciu, Alina; Vartdal, Frode; Holmøy, Trygve; Vedeler, Christian A.; Lossius, Peter Andreas Vold (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    We have previously shown that plasmablasts of the G1m1 allotype of IgG1 areselectively enriched in the cerebrospinal fluid of G1m1/G1m3 heterozygouspatients with multiple sclerosis, whereas both allotypes are equally used ...
  • Gait and gait variability in individuals with Parkinson’s disease: validity, reliability and long-term effects of intensive balance and gait training 
    Rennie, Linda (Doctoral thesis / Doktoravhandling, 2020)
    Many individuals with Parkinson’s disease (PD), a degenerative neurological disorder affecting the basal ganglia, experience disturbances of postural control and gait. Structured exercise is an integral part of PD-management, ...
  • Galectin-3, a marker of cardiac remodeling, is inversely related to serum Levels of marine omega-3 fatty acids. A cross-sectional study 
    Laake, K; Seljeflot, Ingebjørg; Schmidt, EB; Myhre, Peder Langeland; Tveit, Arnljot; Nordseth, Jon; Arnesen, Harald; Solheim, Svein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Objective: Marine polyunsaturated n-3 fatty acids (n-3 PUFA) may have cardioprotective effects and beneficial influence on the fibrotic process. We evaluated the associations between serum marine n-3 PUFA and selected ...
  • Gastrectomy for metastatic gastric cancer: a 15-year experience from a developing country 
    Sahakyan, Mushegh; Gabrielyan, Artak; Aghayan, Davit; Yesayan, Shushan; Petrosyan, Hmayak; Chobanyan, Alina; Kazaryan, Airazat M.; Sahakyan, Artur M. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    The role of surgery in the management of metastatic gastric cancer (MGC) remains unclear. The aim of this study was to investigate the surgical and oncologic outcomes of gastrectomy in patients with MGC. The study included ...
  • Gastric bypass surgery has a weight-loss independent effect on post-challenge serum glucose levels 
    Hofsø, Dag; Birkeland, Kåre I; Holst, Jens J; Bollerslev, Jens; Sandbu, Rune; Røislien, Jo; Hjelmesæth, Jøran (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background Gastric bypass surgery seems to have an effect on glucose metabolism beyond what is mediated through weight reduction. The magnitude of this effect on fasting and post-challenge glucose levels ...
  • Gastric bypass versus sleeve gastrectomy in patients with type 2 diabetes (Oseberg): a single-centre, triple-blind, randomised controlled trial 
    Hofsø, Dag; Fatima, Farhat; Borgeraas, Heidi; Birkeland, Kåre I.; Gulseth, Hanne Løvdal; Hertel, Jens Kristoffer; Johnson, Line Kristin; Lindberg, Morten; Nordstrand, Njord; Småstuen, Milada Cvancarova; Stefanovski, Darko; Svanevik, Marius; Valderhaug, Tone Gretland; Sandbu, Rune; Hjelmesæth, Jøran (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Background For patients with obesity and type 2 diabetes, weight loss improves insulin sensitivity and β-cell function, and can induce remission of diabetes. The comparative efficacy of various bariatric procedures for ...
  • Gastric sleeve resection as day-case surgery: what affects the discharge time? 
    Aftab, Hira; Fagerland, Morten; Gondal, Ghous; Ghanima, Waleed Khalid; Olsen, Magnus Kringstad; Nordby, Tom (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Background Sleeve gastrectomy, with its short operating time, is possible to perform as same-day surgery, with the most common reason for requiring overnight hospital stay being postoperative nausea and vomiting. Objective To ...
  • Gastro-enteritis outbreak among Nordic patients with psoriasis in a health centre in Gran Canaria, Spain: a cohort study 
    Eriksen, Hanne M; Guerin, Philippe J; Nygård, Karin; Hjertqvist, Marika; de Jong, Birgitta; Rose, Angela M; Kuusi, Markku; Durr, Ulrike; Rojas, AG; Mør, Cato; Aavitsland, Preben (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)
    Background Between November 2 and 10, 2002 several patients with psoriasis and personnel staying in the health centre in Gran Canaria, Spain fell ill with diarrhoea, vomiting or both. Patient original came ...
  • Gastrointestinal involvement in systemic sclerosis: Effects on morbidity and mortality and new therapeutic approaches 
    Hoffmann-Vold, Anna-Maria; Volkmann, Elizabeth R. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    The majority of research studies in systemic sclerosis focus largely on addressing skin and cardiopulmonary manifestations. Fewer studies assess the pathogenesis and treatment of gastrointestinal tract involvement in ...
  • Gastrointestinal symptoms in invasive pneumococcal disease: a cohort study 
    Floeystad, Hans K; Berild, Jacob D; Brandsaeter, Bjoern J; Vestrheim, Didrik F; Berild, Dag; Holm, Are M (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background The study aimed to assess whether gastrointestinal (GI) symptoms at admission are associated with increased short-term mortality in patients with invasive pneumococcal disease (IPD). ...
  • Gastrointestinal toxicity of vorinostat: reanalysis of phase 1 study results with emphasis on dose-volume effects of pelvic radiotherapy 
    Bratland, Åse; Dueland, Svein; Hollywood, Donal; Flatmark, Kjersti; Ree, Anne H (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Background In early-phase studies with targeted therapeutics and radiotherapy, it may be difficult to decide whether an adverse event should be considered a dose-limiting toxicity (DLT) of the investigational ...
  • Gastroscopy assisted laser Doppler flowmetry and visible light spectroscopy in patients with chronic mesenteric ischemia 
    Berge, Simen Tveten; Safi, Nathkai; Medhus, Asle Wilhelm; Ånonsen, Kim Vidar; Sundhagen, Jon Otto; Hisdal, Jonny; Kazmi, Syed Sajid Hussain (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Mucosal pathology due to chronic mesenteric ischemia (CMI) is rarely seen during upper endoscopy. Combining Laser Doppler Flowmetry (LDF) and Visible Light Spectroscopy (VLS) may aid in detection of CMI at an early stage. We ...
  • GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study 
    Rongve, Arvid; Witoelar, Aree; Ruiz, Agustín; Athanasiu, Lavinia; Abdelnour, Carla; Clarimon, Jordi; Heilmann-Heimbach, Stefanie; Hernández, Isabel; Moreno-Grau, Sonia; de Rojas, Itziar; Morenas-Rodríguez, Estrella; Fladby, Tormod; Sando, Sigrid Botne; Bråthen, Geir; Blanc, Frédéric; Bousiges, Olivier; Lemstra, Afina W.; van Steenoven, Inger; Londos, Elisabet; Almdahl, Ina Selseth; Pålhaugen, Lene; Eriksen, Jon Alm; Djurovic, Srdjan; Stordal, Eystein; Saltvedt, Ingvild; Ulstein, Ingun; Bettella, Francesco; Desikan, Rahul S.; Idland, Ane-Victoria; Toft, Mathias; Pihlstrøm, Lasse; Snaedal, Jon; Tárraga, Lluís; Boada, Mercè; Lleó, Alberto; Stefánsson, Hreinn; Stefánsson, Kári; Ramírez, Alfredo; Aarsland, Dag; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. Here we ...
  • The GBA variant E326K is associated with Parkinson's disease and explains a genome-wide association signal 
    Berge-Seidl, Victoria; Pihlstrøm, Lasse; Maple-Grødem, Jodi; Forsgren, Lars; Linder, Jan; Larsen, Jan Petter; Tysnes, Ole-Bjørn; Toft, Harald Mathias Strøm (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Objective: Coding variants in the GBA gene have been identified as the numerically most important genetic risk factors for Parkinson's disease (PD). In addition, genome-wide association studies (GWAS) have identified ...
  • Gender aspects in kidney transplantation 
    Øien, Cecilia M. (Doctoral thesis / Doktoravhandling, 2007)
    Successful kidney transplantation is the best treatment for patients with end stage renal disease and graft survival is one of the most important measures of success in kidney transplantation. The majority of the patients ...
  • Gender but not diabetes, hypertension or smoking affects infarct evolution in ST-elevation myocardial infarction patients – data from the CHILL-MI, MITOCARE and SOCCER trials 
    Nordlund, David; Engblom, Henrik; Bonnet, Jean-Louis; Hansen, Henrik S; Atar, Dan; Erlinge, David; Ekelund, Ulf; Heiberg, Einar; Carlsson, Marcus; Arheden, Håkan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Infarct evolution rate and response to acute reperfusion therapy may differ between patients, which is important to consider for accurate management and treatment of patients with ST-elevation ...
  • Gender differences in all-cause, cardiovascular and cancer mortality during long-term follow-up after acute myocardial infarction; a prospective cohort study 
    Kvakkestad, Kristin M; Wang Fagerland, Morten; Eritsland, Jan; Halvorsen, Sigrun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background Gender differences in short-term mortality in acute myocardial infarction (AMI) have been studied extensively, whereas gender differences in long-term mortality and cause of death largely remain ...
  • Gender differences in association between uric acid and all-cause mortality in patients with chronic heart failure 
    Stubnova, Viera; Os, Ingrid; Høieggen, Aud; Solbu, Marit D; Grundtvig, Morten; Westheim, Arne S; Atar, Dan; Waldum-Grevbo, Bård (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Elevated serum uric acid (SUA) is associated with poor prognosis in patients with cardiovascular disease, yet it is still not decided whether the role of SUA is causal or only reflects an underlying ...
  • Gender differences in health status and benefits of a one-week educational programme for caregivers of cancer patients 
    Gjerset, Gunhild Maria; Tendille, Mari; Skaali, Tone Margrethe Olsbu; Kiserud, Cecilie E.; Dahl, Alv A; Gudbergsson, Sævar Berg; Thorsen, Lene (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Objective The aims of this study were to investigate differences between female and male caregivers’ health status before and 3 months after a one‐week educational programme, self‐reported needs for support and changes ...