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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Mental health disorders are common among people in prison, but their prevalence in the Scandinavian prison population remain unclear. In this multinational register study, we examined the prevalence ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Decisions regarding maintenance therapy in patients with multiple myeloma should be based on both treatment efficacy and health-related quality of life (HRQL) consequences. In the CARFI trial, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Objective
Although knowledge about the experience of being diagnosed with dementia is limited, with the expected rise in dementia’s prevalence in the coming decades, such knowledge is pivotal for the people ...
(Doctoral thesis / Doktoravhandling, 2024)
In recent years, surgical treatment modalities for cervical degenerative disorders have become increasingly more safe and less invasive, and surgical volumes are rising. Although treatment guidelines do exist, there is a ...
(Doctoral thesis / Doktoravhandling, 2024)
The distal radioulnar joint (DRUJ) is important for forearm rotation and lifting capacity. After trauma or degenerative disease, painful arthritis may ensue. Historically, surgical salvage procedures have been used, such ...
(Doctoral thesis / Doktoravhandling, 2024)
Chronic pain is a disabling and distressing health concern that burdens patients, their loved ones, and society at large. To address the complexities of chronic pain, multidisciplinary pain management, including patient ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Objectives
In this cross-sectional study from Botswana, we investigated knowledge of myocardial infarction (MI) symptoms and risk factors among the general public and outpatients with MI risk factors based ...
(Doctoral thesis / Doktoravhandling, 2024)
Antiplatelet therapy has revolutionized the treatment of cardiovascular diseases (CVDs), however, despite the great advances; the risk of new thrombotic events remains high. There is a need for new biomarkers to identify ...
(Doctoral thesis / Doktoravhandling, 2024)
Following organ transplantation life-long immunosuppressive therapy is mandatory. Medication nonadherence (“not taking medication as prescribed”) is one of the main reasons for graft loss during the transition phase from ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Solid benign liver lesions (BLL) are increasingly discovered, but clear indications for surgical treatment are often lacking. Concomitantly, laparoscopic liver surgery is increasingly performed. The aim of this ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Frequently presenting with symptoms of mood or anxiety disorders, substance abuse or borderline personality disorder, suicidal and self-harming adolescents often are prescribed psychotropic ...
(Doctoral thesis / Doktoravhandling, 2024)
Increased knowledge of the mechanics of labour and improved diagnostic methods in labour may improve quality and patient safety. Accurate diagnosis of fetal head rotation and descent is crucial for ensuring high-quality ...
(Doctoral thesis / Doktoravhandling, 2024)
The motion of the heart originates from the electrical activity in the sinoatrial node, which causes the atria to contract. The electrical pulse then propagates to the ventricles through the atrioventricular node and the ...
(Doctoral thesis / Doktoravhandling, 2024)
Haemodynamic and other means of physiologic monitoring, represents the backbone of the research needed to better understand how we can improve cardiopulmonary resuscitation (CPR). It can also be used during CPR to identify ...
(Doctoral thesis / Doktoravhandling, 2024)
“Negative symptoms” is an umbrella term divided into two main dimensions: diminished expression and apathy. Negative symptoms are considered intrinsic to psychotic disorders, yet are also evidently present across a wide ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Interactions between the gut microbiota, diet, and host metabolism contribute to the development of cardiovascular disease, but a firm link between disease-specific gut microbiota alterations ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Crisis resolution teams (CRTs) have become a part of mental health services in many high-income countries. Many studies have investigated the impact of CRTs on acute admissions to inpatient units, ...
(Doctoral thesis / Doktoravhandling, 2024)
Preterm birth, defined as birth before gestational week 37 is a major challenge in obstetric and perinatal medicine.
The aim of this thesis was to assess associations between maternal country of birth, previous preterm ...
(Doctoral thesis / Doktoravhandling, 2024)
Our research group has previously shown that CCN2 is secreted as a preproprotein that requires proteolytic activation in order to release the biologically active entity. CCN5 is a divergent member of the cellular communication ...
(Doctoral thesis / Doktoravhandling, 2024)
Survival of patients with colorectal cancer (CRC) has improved throughout the past forty years, but to date outcomes are heterogeneous. The aims of the thesis were to describe survival trends of colon cancer in Norway and ...
(Doctoral thesis / Doktoravhandling, 2024)
This thesis describes a new optically based non-invasive method for measuring ocular surface microcirculation.
Oxygen transfers from inhaled air in the lungs to red blood cells, which travel through the vessel network, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
There is scarce knowledge on the health care follow-up of parents of terror attack survivors. This study focused on the mothers and fathers of survivors and examined (1) their perceived health ...
(Doctoral thesis / Doktoravhandling, 2024)
Juvenile Dermatomyositis (JDM) is a rare autoimmune disease of childhood. It involves vasculopathy and chronic inflammation, leading to distinct skin rash, muscle weakness and potential organ involvement, such as reduced ...
(Doctoral thesis / Doktoravhandling, 2024)
Hand osteoarthritis is a common condition which may lead to severe pain and disability. However, the pain intensity does not always correlate with the degree of structural changes. The aim of this thesis was therefore to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Long-term stress causing altered hypothalamic–pituitary–adrenal (HPA) axis dynamics with cortisol dysfunction may be involved in the pathophysiology of functional somatic disorders (FSD), but ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Acutely ill and frail older adults and their next of kin are often poorly involved in treatment and care decisions. This may lead to either over- or undertreatment and unnecessary burdens. The ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Deposition of amyloid beta (Aβ) into plaques is a major hallmark of Alzheimer’s disease (AD). Different amyloid precursor protein (APP) mutations cause early-onset AD by altering the production or aggregation properties ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Evidence on the value of minimally invasive pancreatic surgery (MIPS) has been increasing but it is unclear how this has influenced the view of pancreatic surgeons on MIPS.
Methods
An anonymous survey was ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Dietary sulfur amino acid restriction (SAAR) improves metabolic health in animals. In this study, we investigated the effect of dietary SAAR on body weight, body composition, resting metabolic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
The reconstruction of clonal families (CFs) in B-cell receptor (BCR) repertoire analysis is a crucial step to understand the adaptive immune system and how it responds to antigens. The BCR repertoire of an individual is ...
(Doctoral thesis / Doktoravhandling, 2024)
There is a lack of optimal clinical tools to help identify a fetus at risk of fetal distress and adverse delivery outcome. The maternal circulating placenta-associated proteins placental growth factor (PlGF) and soluble ...
(Doctoral thesis / Doktoravhandling, 2024)
The Human Leukocyte Antigen (HLA) region accounts for a relatively small segment of approximately 4 million base pairs in chromosome 6 occupying only 0.13% of the entire human genome, yet this small region has been established ...
(Doctoral thesis / Doktoravhandling, 2024)
Parkinson's disease (PD) is an age-related neurodegenerative disorder characterized by motor and non-motors symptoms. Cognitive decline and dementia are among the most debilitating non-motor features with a heterogenous ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Communication between patients and healthcare providers, and effective interprofessional communication, are essential to the provision of high-quality care. Implementing a patient-centred approach ...
(Doctoral thesis / Doktoravhandling, 2024)
Dermatitis herpetiformis (DH), an inflammatory skin condition, is considered an extraintestinal manifestation of celiac disease (CeD). Individuals carrying HLA-DQ2.5, HLA-DQ8, or HLA-DQ2.2 are predisposed to both CeD and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
SARS-CoV-2 reinfection rates have been shown to vary depending on the circulating variant, vaccination status and background immunity, as well as the time interval used to identify reinfections. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Objective
To understand community perspectives on the effects of high ambient temperature on the health and wellbeing of neonates, and impacts on post-partum women and infant care in Kilifi.
...
(Doctoral thesis / Doktoravhandling, 2024)
The IBSEN cohort included every patient diagnosed with inflammatory bowel disease (IBD) in South-Eastern Norway from 1990 to 1994. IBD consists of ulcerative colitis (UC) and Crohn’s disease (CD), it is a chronic, lifelong ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
The main focus on the characteristics of malignant lung tumours has been the size, position within the lobe, and infiltration into neighbouring structures. The aim of this study was to investigate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Patients with heart failure (HF) and colorectal cancer (CRC) are prone to comorbidity, a high rate of readmission, and complex healthcare needs. Self-care for people with HF and CRC after ...
(Doctoral thesis / Doktoravhandling, 2024)
Chronic low back pain affects people of all ages, genders, and ethnicities, and contributes to disability and lost productivity worldwide. Unfortunately, the underlying cause of the pain is often unknown, and treatment ...
(Doctoral thesis / Doktoravhandling, 2024)
Patients with cancer have increased risk of venous thrombosis, which are often treated with expensive anticoagulants administered as injections. Patients without cancer are mostly treated with cheaper oral anticoagulants ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Disease-modifying antirheumatic drugs (DMARDs) are widely used for treating rheumatoid arthritis (RA). However, there are no established biomarkers to predict a patient’s response to these ...
(Doctoral thesis / Doktoravhandling, 2024)
Lung cancer is an aggressive disease with a poor prognosis, apparently worse in males than females. The diagnostic process is complex and time-consuming, and diagnostic delays can affect treatment possibilities and ...
(Doctoral thesis / Doktoravhandling, 2024)
A displaced femoral neck fracture (FNF) is a severe injury and will require hospitalization and surgery. The most common treatment options in Norway for FNFs are closed reduction and internal fixation (IF), hemiarthroplasty ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background.
Trabecular bone score (TBS) is a new tool to assess trabecular bone microarchitecture based on standard dual-energy x-ray absorptiometry (DXA) of lumbar spine images. TBS may be important to assess bone ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Although dysphagia is a common side effect after radiotherapy (RT) of head and neck cancer (HNC), data on long-term dysphagia is scarce. We aimed to 1) compare radiation dose parameters in HNC survivors with ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Aims To explore how long‐term and late effects of paediatric brain tumours influence the everyday lives of survivors at various ages and their parents. Design A qualitative interview study using reflexive thematic ...
(Doctoral thesis / Doktoravhandling, 2024)
The DSM-5 Alternative Model for Personality Disorders redefines personality disorders (PDs) in terms of impairments in personality functioning and pathological personality traits.
Especially, the introduction of the Levels ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
High somatic comorbidity is common among patients in treatment for opioid use disorder (OUD). The present study aims to investigate changes in self-reported somatic health conditions and somatic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Intravitreal injections (IVIs) are widely used to deliver therapeutic agents for various retinal conditions. The syringe accuracy is a critical factor in achieving optimal treatment outcomes and minimizing potential risks ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background & Aims
There is controversy regarding the optimal calcineurin inhibitor type after liver transplant(ation) (LT) for primary sclerosing cholangitis (PSC). We compared tacrolimus with cyclosporine in a propensity ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract
Purpose
To analyze tumor characteristics derived from pelvic magnetic resonance imaging (MRI) of patients with squamous cell carcinoma of the anus (SCCA) before and during chemoradiotherapy ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Multiple cognitive domains, including learning, memory, and psychomotor speed, show significant reductions with age. Likewise, several cerebrospinal fluid (CSF) neurodegenerative biomarkers, including total tau (t-tau, a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract
Purpose
Teleultrasound uses telecommunication technologies to transmit ultrasound images from a remote location to an expert who guides the acquisition of images and interprets them in real ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract To evaluate objective time consumption and how nurses perceived introducing wireless patient monitoring (WPM) and a validated score on patient quality and safety, the Efficacy Safety Score (ESS), at a mixed surgery ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Despite the proven effects of statins in preventing cardiovascular disease, their diabetogenic effect has caused concern. The mechanism of this diabetogenic effect is unknown. We suggest a novel mechanism that may ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Introduction
Self-perceived health status data is usually collected using patient-reported outcome measures. Information from the patients’ perspective is one of the important components in planning person-centred care. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Carriers of the 1q21.1 distal and 15q11.2 BP1-BP2 copy number variants exhibit regional and global brain differences compared with noncarriers. However, interpreting regional differences is challenging if a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Daphne mezereum L., an important medicinal plant in Scandinavian folk medicine, was used to treat ailments such as diarrhea, swelling and stomach pain. A range of natural compounds have been isolated, but little attention ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Purpose
The objective of this study was to compare the efficacy of a low-cost heat-preserving method in preventing intraoperative hypothermia with that of forced-air warming in a resource-limited setting.
Methods
In ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background: Severe obesity is associated with increased risk of non-alcoholic fatty liver disease and cardiovascular disease. We hypothesized that liver fibrosis as quantified by the Enhanced Liver Fibrosis (ELF) test would ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Gestational diabetes mellitus (GDM) and type 2 diabetes mellitus (T2DM) share many pathophysiological factors including genetics, but whether epigenetic marks are shared is unknown. We aimed to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Introduction
Chronic pain patients may be at an increased risk for drug overdoses as a result of comorbid psychiatric disorders and treatment with risk-increasing prescription medications, such as opioids. We aimed to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Objectives To understand treatment practices for bipolar disorders (BD), this study leveraged the Global Bipolar Cohort collaborative network to investigate pharmacotherapeutic treatment patterns in multiple ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Today, the majority of patients with pediatric B cell precursor acute lymphoblastic leukemia (BCP-ALL, hereafter ALL) survive their disease, but many of the survivors suffer from life-limiting late effects of the treatment. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Objectives To evaluate long‐term effects, complications and satisfaction among patients treated with AdVance™ and AdVance™ XP slings (AS) at a Norwegian specialist care hospital. Materials and Methods Patients ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Teleological reasoning is the tendency for humans to see purpose and intentionality in natural phenomena when there is none. In this study, we assess three competing theories on how bias in reasoning arises by ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background The cornea, a vital component of the human eye, plays a crucial role in maintaining visual clarity. Understanding its ultrastructural organization and cell distribution is fundamental for elucidating corneal ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2024)
Background
There are limited data on the long-term risk of venous thromboembolism (VTE) after high-risk isolated superficial vein thrombosis (iSVT) treated with anticoagulants.
Objectives
To determine the short- and ...
(Doctoral thesis / Doktoravhandling, 2024)
Agitation is a state of restlessness and excessive psychomotor activity accompanied by anxiety, irritability, and impaired impulse control. Despite that agitation is a particularly challenging clinical feature, therapeutic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract
Objectives
We aimed to discover CpG sites with differential DNA methylation in peripheral blood leukocytes associated with body mass index (BMI) in pregnancy and gestational weight gain (GWG) ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Stroke is one of the most common causes of acquired epilepsy, which can also result in disability and increased mortality rates particularly in elderly patients. No preventive treatment for post-stroke epilepsy is currently ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Background Patients undergoing caesarean delivery are at risk of developing unintended perioperative hypothermia, defined as a core temperature <36.0°C. Most previous studies of core temperature in caesarean ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Personality disorders (PDs) are associated with high levels of societal costs, regardless of whether a single PD or a broad range of PDs have been studied. However, research on the relative contribution of specific ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Adolescent suicide attempts are on the rise, presenting a significant public health concern. Recent research aimed at improving risk assessment for adolescent suicide attempts has turned to machine learning. But ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract The intensity of the conditioning regimen given before allogeneic hematopoietic cell transplantation (allo-HCT) can vary substantially. To confirm the ability of the recently developed transplant conditioning ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Objectives This study aims to assess risk factors for SARS-CoV-2 infection by combined design; first comparing positive cases to negative controls as determined by PCR testing and then comparing these two groups to an ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Norway has a long coastline, steep mountains, and wide fjords, which presents some challenges to the prehospital emergency healthcare system. In recent years, the prehospital emergency medical services (EMS) ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Introduction We aimed to compare placental size and placental size relative to fetal size (ratio) in ongoing pregnancies examined by magnetic resonance imaging (MRI) at gestational week 36 with placental size ...
(Doctoral thesis / Doktoravhandling, 2024)
We may all experience trauma, such as violence and accidents. These may elicit profound long-term alterations in biological, psychological, and social responses. The changes may reflect the deep and complex influence that ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Aquaculture is the fastest-growing food sector worldwide but faces sustainability challenges that need to be addressed in many ways, including genetic enhancement. Atlantic cod has re-emerged as an aquaculture species and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Objective
We investigated methotrexate safety and the influence of dose on efficacy outcomes in combination with three different biologic treatments and with active conventional treatment (ACT) in early rheumatoid arthritis ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Background Prognosis after out‐of‐hospital cardiac arrest (OHCA) is presumed poorer in patients with non‐shockable than shockable rhythms, frequently leading to treatment withdrawal. Multimodal outcome prediction ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract
Purpose
Chronic obstructive Eustachian tube dysfunction (OETD) can lead to tympanic membrane (TM) retraction and middle ear effusion (MEE) which can cause conductive hearing impairment, which ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Bakgrunn
Kunnskap om psykiske lidelser blant pasienter med vedvarende opioidbruk for behandling av langvarige ikke-kreftrelaterte smerter er viktig, da psykiske lidelser og plager kan bidra til å forsterke eller ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
More than 90 % of patients developing heart failure (HF) have hypertension. The most frequent concomitant conditions are type-2 diabetes mellitus, obesity, atrial fibrillation, and coronary disease. HF outcome research ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Objective: In Norway, 89% of patients with Amyotrophic lateral sclerosis (ALS) lacks a genetic diagnose. ALS genes and genes that cause other neuromuscular or neurodegenerative disorders extensively overlap. This ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
P-glycoprotein (P-gp, encoded in humans by the ABCB1 gene and in rodents by the Abcb1a/b genes) is a membrane transporter that can restrict the intestinal absorption and tissue distribution of many drugs and may also ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Immune thrombocytopenia (ITP) is characterized by reduced platelet count due to increased destruction and is categorized according to the time following diagnosis (newly diagnosed, persistent, chronic). First‐line ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background and aims Statin-associated muscle symptoms (SAMS) is a prevalent cause of statin discontinuation. It is challenging and time-consuming for clinicians to assess whether symptoms are caused by the statin or not, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background: Schizophrenia (SCZ) is a heritable disorder with a polygenic architecture, and the gut microbiota seems to be involved in its development and outcome. In this study, we investigate the interplay between genetic ...
(Doctoral thesis / Doktoravhandling, 2024)
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiovascular disease. The aim of this Ph.D. was to provide a basis for advice regarding exercise training for patients with a genetic predisposition for HCM. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
The HLA complex is the most polymorphic region of the human genome, and its improved characterization can help us understand the genetics of human disease as well as the interplay between cancer ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
The mouth is a central organ for communication and fluid intake, also for dying nursing home patients. This study describes the prevalence and severity of oral symptoms from nursing home admission ...
(Doctoral thesis / Doktoravhandling, 2024)
Sepsis is a highly lethal syndrome of organ failure, infection and dysregulated immune responses. Despite extensive research, the treatment of sepsis has remained largely unchanged for decades. The lack of scientific ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Adverse pregnancy outcomes (APO) may unmask or exacerbate a woman’s underlying risk for coronary heart disease (CHD). We estimated associations of maternal and paternal genetically predicted ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract
Parkinson’s disease is an age-related neurodegenerative disorder with a higher incidence in males than females. The causes for this sex difference are unknown. Genome-wide association studies (GWAS) have ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Aim Respiratory tract infections (RTIs) are major contributors to childhood antibiotic use. We aimed to investigate geographical and temporal trends in the prescription of antibiotics and consultations for RTIs ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract
Opioid and nonopioid analgesics are commonly prescribed to young people to alleviate pain. Even short-term prescriptions increase the risk of persistent use and future misuse of potent analgesics, such as ...