Browsing Institutt for klinisk medisin by Title
Now showing items 8-27 of 2553
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background There have been few studies of how personal and instrumental activities of daily living (P-ADL and I-ADL) develop over time in older people receiving domiciliary care. This study aimed at assessing ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Background Few have studied how personal activities of daily living (P-ADL) develop over time in nursing home residents with dementia. Thus, the aim was to study variables associated with the development ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background A Bayesian mixed model approach using integrated nested Laplace approximations (INLA) allows us to construct flexible models that can account for pedigree structure. Using these models, we estimate ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)Background Deproteinized DNA from eukaryotic and prokaryotic cells still contains a low-molecular weight peptidic fraction which can be dissociated by alkalinization of the medium. This fraction inhibits ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background ChIP-seq is the primary technique used to investigate genome-wide protein-DNA interactions. As part of this procedure, immunoprecipitated DNA must undergo “library preparation” to enable subsequent ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Little is known about the psychological prerequisites for weight loss maintenance after bariatric surgery. A first step in investigating whether existing knowledge of conservative weight loss ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background There is considerable evidence that many complex traits have a partially shared genetic basis, termed pleiotropy. It is therefore useful to consider integrating genome-wide association study ...
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A CpG island hypermethylation profile of primary colorectal carcinomas and colon cancer cell lines (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)Background Tumor cell lines are commonly used as experimental tools in cancer research, but their relevance for the in vivo situation is debated. In a series of 11 microsatellite stable (MSS) and 9 ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)The objective was to investigate the prevalence and interrelation of migraine and headache in the general population. Forty thousand men and women aged 20–80 years from the Norwegian general population received a mailed ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background Previous research on mental health care has shown considerable differences in use of seclusion, restraint and involuntary medication among different wards and geographical areas. This study ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background Involuntary care and coercive measures are frequently present in mental healthcare for adolescents. The purpose of this study was to examine to what extent adolescents perceive or experience ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Epidemiological studies have consistently established high comorbidity between psychiatric disorders and substance use disorders (SUD). This comorbidity is even more prominent when psychiatric ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Patients suspected of personality disorders (PDs) by general practitioners are frequently referred to psychiatric outpatient clinics (POCs). In that setting an effective screening instrument for ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Introduction Prognosis in rheumatoid arthritis (RA) is difficult to assess. The aim of this study was to examine whether serum levels of a spectrum of cytokines were predictive of radiographic progression ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)Background As farming of Atlantic salmon is growing as an aquaculture enterprise, the need to identify the genomic mechanisms for specific traits is becoming more important in breeding and management of the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background The aim of this study was to investigate whether childhood trauma was associated with more severe clinical features in patients with first-episode psychosis, both at the initial assessment and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)The recently discovered HEAT-like repeat (HLR) DNA glycosylase superfamily is widely distributed in all domains of life. The present bioinformatics and phylogenetic analysis shows that HLR DNA glycosylase superfamily members ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background The major rate-limiting enzyme for de novo cholesterol synthesis is 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR). HMGCR is sterically inhibited by statins, the most commonly prescribed ...