Browsing Institutt for klinisk medisin by Title
Now showing items 6002-6021 of 7899
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Internal therapy with α‐emitters should be well suited for micrometastatic disease. Radium‐224 emits multiple α‐particles through its decay and has a convenient 3.6 days of half‐life. Despite its attractive properties, the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Abstract HER2 is a predictive biomarker for HER2-targeted therapeutics. For antibody–drug conjugates (ADCs; e.g., trastuzumab emtansine (T-DM1)), HER2 is utilized as a transport gate for cytotoxic agents into the cell. ADC ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Rab proteins are master regulators of intracellular membrane trafficking, but they also contribute to cell division, signaling, polarization, and migration. The majority of the works describing the mechanisms used by Rab ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Globally, rabies remains a serious threat to public health. In particular, large number of cases continue to be detected in Africa and Asia. China has experienced three major outbreaks with the current epizootic starting ...
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Race duration and blood pressure are major predictors of exercise-induced cardiac troponin elevation (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Background The underlying mechanisms of the exercise-induced increase in cardiac troponins (cTn) are poorly understood. The aim of this study was to identify independent determinants of exercise-induced cTn increase in a ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Acute bronchiolitis in infants, which frequently leads to hospitalization and sometimes requires ventilatory support, is occasionally fatal; it is usually viral in origin, with respiratory syncytial virus being the most ...
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(Doctoral thesis / Doktoravhandling, 2016)This is a feasibility study in using radar for estimating blood pressure and which could allow for continuous, non-invasive measurements both inside and outside the clinic. Blood pressure has extensive use in emergency ...
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Radiation Doses in Medical Imaging : Historical development, current radiation knowledge and future (Doctoral thesis / Doktoravhandling, 2012)
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(Doctoral thesis / Doktoravhandling, 2018)Calvé-Legg-Perthes er en hoftesykdom som skyldes et fullstendig eller delvis opphør av blodtilførselen til lårbenshodet. Årsaken er ukjent. Sykdommen er mest vanlig i 5-6 års alderen. I de aktive stadiene av sykdommen ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Using magnetic resonance imaging (MRI) to relate cardiovascular structures to surface anatomy in a population relevant to cardiac arrest victims, relate the external thoracic anterior-posterior ...
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(Doctoral thesis / Doktoravhandling, 2012)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Background Misinterpretation of radiological examinations is an important contributing factor to diagnostic errors. Consultant radiologists in Norwegian hospitals frequently request second reads by colleagues in real time. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Objectives: To describe the use of radiology in the emergency department (ED) in a trauma centre during a mass casualty incident, using a minimum acceptable care (MAC) strategy in which CT was restricted to potentially ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)A suspension of 224Ra adsorbed onto CaCO3 microparticles shows promise for α-therapy of intracavitary micro-metastatic diseases. To facilitate accurate activity administrations, geometry-specific calibration factors for ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background The histone deacetylase inhibitor vorinostat is a candidate radiosensitizer in locally advanced rectal cancer (LARC). Radiosensitivity is critically influenced by hypoxia; hence, it is important ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)Background The tumor response to preoperative radiotherapy of locally advanced rectal cancer varies greatly, warranting the use of experimental models to assay the efficacy of molecular targeting agents ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)Background Novel cancer drugs are subject to strict scientific evaluation of safety and efficacy and usually undergo a cost effectiveness analysis before approval for use in clinical practice. For new techniques in ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)Aims To evaluate metastatic lesions within the radiation field using repeated magnetic resonance imaging (MRI) and to compare the imaging findings with pain response following radiotherapy (RT) in patients with spinal ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Alpha-particle emitting radionuclides continue to be the subject of medical research because of their high energy and short range of action that facilitate effective cancer therapies. Radium-224 ( 224 Ra) is one such ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)Background Ketorolac is an effective non‐steroidal anti‐inflammatory drug, commonly used with local anaesthetics as part of local infiltration analgesia protocols following orthopaedic surgery. However, systemic uptake ...