Browsing Institutt for klinisk medisin by Title
Now showing items 5937-5956 of 10728
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background: N6-methyladenosine (m6A) is one of the most abundant post-transcriptional modifications on mRNA influencing mRNA metabolism. There is emerging evidence for its implication in metabolic disease. No comprehensive ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Objective We aimed to explore the added value of common machine learning (ML) algorithms for prediction of outcome for moderate and severe traumatic brain injury. Study Design and Setting We performed logistic ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Celiac disease (CeD) is a common autoimmune disorder caused by an abnormal immune response to dietary gluten proteins. The disease has high heritability. HLA is the major susceptibility factor, and the HLA effect is mediated ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2023)Antimicrobial peptides (AMPs) are short peptides with a broad spectrum of antimicrobial activity. They play a key role in the host innate immunity of many organisms. The growing threat of microorganisms resistant to ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)Objective: Evaluation of intestinal viability is essential in surgical decision-making in patients with acute intestinal ischemia. There has been no substantial change in the mortality rate (30-93%) of patients with acute ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background We aim to implement an immune cell score model in routine clinical practice for resected non-small-cell lung cancer (NSCLC) patients (NCT03299478 ). Molecular and genomic features associated with immune ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background: Detailed pathology analysis and morphological quantification is tedious and prone to errors. Automatic image analysis can help to increase objectivity and reduce time. Here, we present the evaluation of the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Abstract Antibodies are versatile molecular binders with an established and growing role as therapeutics. Computational approaches to developing and designing these molecules are being increasingly used to ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract Background and purpose A heart age biomarker has been developed using deep neural networks applied to electrocardiograms. Whether this biomarker is associated with cognitive function was investigated. Methods ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background Low back pain (LBP) is a leading cause of disability worldwide, but the aetiology remains poorly understood. Finding relevant biomarkers may lead to better understanding of disease mechanisms. Patients with ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background: Epicardial and pericardial adipose tissue (EAT and PAT) surround and protect the heart, with EAT directly sharing the microcirculation with the myocardium, possibly presenting a distinct macrophage phenotype ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)COVID-19 has caused worldwide death and economic destruction. The pandemic is the result of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has demonstrated high rates of infectivity leading to great ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)Background and Aims Certain appearances of the major duodenal papilla have been claimed to make cannulation more difficult during ERCP. This study uses a validated classification of the endoscopic appearance of the major ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Ageing people with hemophilia (PWH) have a higher prevalence of hypertension than the general population. This study aimed to determine whether macroscopic hematuria was associated with hypertension in PWH in a post hoc ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Purpose: The study aims to determine the anatomical success and functional outcome of pars plana vitrectomy (PPV) for macular holes (MH) performed at a single study center using a consistent procedure of internal limiting ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Purpose: The purpose of this study was to investigate associations between cardiovascular risk factors and the thickness of retinal nerve fiber layer (RNFL), ganglion cell-inner plexiform layer (GCIPL), and outer retina ...
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(Doctoral thesis / Doktoravhandling, 2015)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Abstract Disturbed clearance of toxic metabolites from the brain via cerebrospinal fluid is emerging as an important mechanism behind dementia and neurodegeneration. To this end, magnetic resonance imaging work-up ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Purpose Cervical disc prostheses induce significant amount of artifact in magnetic resonance imaging which may complicate radiologic follow-up after surgery. The purpose of this study was to investigate as to what extent ...
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(Doctoral thesis / Doktoravhandling, 2018)Inflammatorisk tarmsykdom (IBD) er en kronisk tilstand som oftest rammer unge mennesker. Etiologien er kun delvis kartlagt og forekomsten er økende. Magesmerter, diare og fatigue er typiske symptomer. IBD rammer i tillegg ...