Browsing Institutt for klinisk medisin by Title
Now showing items 4689-4708 of 10728
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Internal solitary waves (ISWs) of large amplitude moving in the coastal ocean induce sizeable horizontal velocities above the sea bed. In turn, these give rise to instability and vortex formation in the bottom boundary ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background Women who exercise intensively, whether competitive or recreational, devote a lot of time and energy into exercise, which requires high levels of ambition and motivation. The aim of the study is ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background A considerable body of research has explored implications of severe parental illness on children. However, less is known about what children and adolescents with a severely ill parent experience as the most ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Abstract Purpose Living with late effects can affect young childhood cancer survivors’ (CCSs) self-management (SM) abilities. In this study, we explored different approaches to SM of everyday life by ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)We aimed to explore how many of the politically active, highly media- exposed, young survivors of the terrorist attack on Utøya island, Norway, have had personal experiences with hate speech and threats post-terror. Further, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Iatrogenic vascular air embolism is a relatively infrequent event but is associated with significant morbidity and mortality. These emboli can arise in many clinical settings such as neurosurgery, cardiac surgery, and liver ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background We describe a patient presenting with central retinal artery occlusion (CRAO) of the right eye after retrobulbar anesthesia with adrenaline for macular pucker surgery. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background Immunotherapy with checkpoint inhibitors (CPI) targeting PD-1 or CTLA-4 has emerged as an important treatment modality for several cancer forms. In hormone receptor positive breast cancer (HR + BC), this ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background Multiple myeloma (MM) cancers originate from plasma cells that have passed through the germinal center reaction where somatic hypermutation of Ig V regions takes place. Myeloma protein V regions often express ...
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(Doctoral thesis / Doktoravhandling, 2009)ATP-binding cassette (ABC) transporters are integral components of most living cells and constitute a large group of structurally related transmembrane proteins. These transporters translocate a wide variety of substrates ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)The genes PRKACA and PRKACB encode the principal catalytic (C) subunits of protein kinase A (PKA) Cα and Cβ, respectively. Cα is expressed in all eukaryotic tissues examined and studies of Cα knockout mice demonstrate a ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Autoimmune Addison's disease (AAD) is a classic organ-specific autoimmune disease characterized by an immune-mediated attack on the adrenal cortex. As most autoimmune diseases, AAD is believed to be caused by a combination ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background The tumor suppressor pRb plays a key role regulating cell cycle arrest, and disturbances in the RB1 gene have been reported in different cancer forms. However, the literature reports contradictory ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background More accurate risk assessments are needed to improve prostate cancer management. Objective To identify blood-based protein biomarkers that provided prognostic information for risk stratification. Design, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)The ubiquitin-proteasome system (UPS) and macroautophagy/autophagy are the main proteolytic systems in eukaryotic cells for preserving protein homeostasis, i.e., proteostasis. By facilitating the timely destruction of ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Abstract Clozapine (CLZ) is the superior antipsychotic drug for treatment of schizophrenia, but exhibits an extensive interpatient pharmacokinetic variability. Here, we conducted a genome-wide association study ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2006)The polymeric Ig receptor (pIgR), also called membrane secretory component (SC), mediates epithelial transcytosis of polymeric immunoglobulins (pIgs). J Chain-containing polymeric IgA (pIgA) and pentameric IgM bind pIgR ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Recurrent chromosomal translocations leading to gene fusion formation have been described in uterine sarcomas, including low-grade endometrial stromal sarcoma (LG-ESS). Involvement of the PHF1 gene in chromosomal rearrangements ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background The presence of cancer-specific DNA methylation patterns in epithelial colorectal cells in human feces provides the prospect of a simple, non-invasive screening test for colorectal cancer and its ...