Browsing Institutt for klinisk medisin by Title
Now showing items 1299-1318 of 10727
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)The chemokine C-C motif ligand 20 (CCL20) is increased in the colonic mucosa during active inflammatory bowel disease (IBD) and can be found both in the epithelium and immune cells in the lamina propria. The present study ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)The transcription factor c-Myb is involved in early differentiation and proliferation of haematopoietic cells, where it operates as a regulator of self-renewal and multi-lineage differentiation. Deregulated c-Myb plays ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)C‐type lectin‐like CD161, a class II transmembrane protein, is a surface receptor expressed by NK cells and T cells. In coeliac disease, CD161 was expressed more frequently on gluten‐reactive CD4 + T cells compared to other ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Objective: The chemokine CXCL16 (C-X-C motif ligand 16) is a scavenger receptor for OxLDL (oxidized low-density lipoproteins) and involved in inflammation at sites of atherosclerosis. This study aimed to investigate the ...
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C. elegans as an Animal Model to Study the Intersection of DNA Repair, Aging and Neurodegeneration (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Since its introduction as a genetic model organism, Caenorhabditis elegans has yielded insights into the causes of aging. In addition, it has provided a molecular understanding of mechanisms of neurodegeneration, one of ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)The pan lymphocyte marker CD45 exists in various isoforms arising from alternative splicing of the exons 4, 5 and 6. While naïve T cells express CD45RA translated from an mRNA containing exon 4, exons 4–6 are spliced out ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Objective: We sought to characterize C9orf72 expansions in relation to genetic ancestry and age at onset (AAO) and to use these measures to discriminate the behavioral from the language variant syndrome in a large pan-European ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Based on literature reports of the last two decades, a computer-aided pattern analysis (C@PA) was implemented for the discovery of novel multitarget ABCB1 (P-gp), ABCC1 (MRP1), and ABCG2 (BCRP) inhibitors. C@PA included ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Epileptic seizures are associated with increased astrocytic Ca2+ signaling, but the fine spatiotemporal kinetics of the ictal astrocyte–neuron interplay remains elusive. By using 2-photon imaging of awake head-fixed mice ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)The effect of poly(2-ethyl-butyl cyanoacrylate) nanoparticles containing the cytotoxic drug cabazitaxel was studied in three breast cancer cell lines and one basal-like patient-derived xenograft model grown in the mammary ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Objectives To evaluate the association between caesarean section and migraine in a population-based register-linked cohort study. Setting Data from the population-based Nord-Trøndelag Health Studies (HUNT2 and HUNT3) were ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Objective: To analyse the current situation of caesarean section in Palestine using the Robson Ten Group Classification System (TGCS). Methods: The contributions of each group to the study population and to the overall ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background Fixation of proximal humeral fractures (PHF) with locking plates has gained popularity over conservative treatment, but surgery may be complicated with infection, non-union, avascular necrosis ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background: Patients with advanced-stage ovarian cancer face a poor prognosis because of recurrent peritoneal cavity metastases following surgery and chemotherapy. Alpha-emitters may enable the efficient treatment of such ...
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(Doctoral thesis / Doktoravhandling, 2023)Altered Ca2+ handling in cardiomyocytes can lead to arrhythmias in the rare, inherited disorder catecholaminergic polymorphic ventricular tachycardia type 1 (CPVT1), and in the early reperfusion phase following a myocardial ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background and purpose: The evaluation of metaphyseal angular deformities in children includes indication and timing for corrective osteotomy, and possible need for several operations during growth. Gap-fillers are usually ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Offspring outcomes are a function of maternal genetics operating on the intrauterine and postnatal environment, offspring genetics and environmental factors. Partitioning genetic effects into maternal and offspring components ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Lead-212 is a promising radionuclide for cancer therapy, but no primary 212Pb activity standardization has been published. A need therefore exists for accurate estimation of injected doses of 212Pb activity in equilibrium ...