Browsing Institutt for klinisk medisin by Title

Now showing items 5917-5936 of 10751

  • Low pain tolerance is associated with coronary angiography, coronary artery disease, and mortality: The TROMSO study 
    Fladseth, Kristina; Lindekleiv, Haakon; Nielsen, Christopher Sivert; Øhrn, Andrea; Kristensen, Andreas; Mannsverk, Jan Torbjørn; Løchen, Maja-Lisa; Njølstad, Inger; Wilsgaard, Tom; Mathiesen, Ellisiv B.; Stubhaug, Audun; Trovik, Thor; Rotevatn, Svein; Forsdahl, Signe Helene; Schirmer, Henrik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background The initial presentation to coronary angiography and extent of coronary artery disease (CAD) vary greatly among patients, from ischemia with no obstructive CAD to myocardial infarction with 3‐vessel disease. ...
  • Low versus High Intracranial Compliance in Adult Patients with Chiari Malformation Type 1–Comparison of Long-Term Outcome After Tailored Treatment 
    Frič, Radek; Ringstad, Geir; Eide, Per Kristian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background In patients with Chiari malformation type 1 (CMI) presenting with low intracranial compliance (ICC), foramen magnum decompression (FMD) often fails and the complication rate may be higher. We therefore routinely ...
  • Low vitamin D is associated with negative and depressive symptoms in psychotic disorders 
    Nerhus, Mari; Berg, Akiah O.; Kvitland, Levi R.; Dieset, Ingrid; Hope, Sigrun; Dahl, Sandra R.; Weibell, Melissa A.; Romm, Kristin L.; Faerden, Ann; Andreassen, Ole A.; Melle, Ingrid (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
    Background There are indications that low S-25(OH)D is associated with increased disease severity in psychotic disorder. Our first aim was to investigate the relations between low S-25(OH)D and positive, negative and ...
  • Low vitamin D, but not tobacco use or high BMI, is associated with long-term disability progression in multiple sclerosis 
    Wesnes, Kristin; Myhr, Kjell-Morten; Riise, Trond; Stokke, Silje Agnethe; Torkildsen, Øivind; Wergeland, Stig; Holmøy, Trygve; Midgard, Rune; Bru, Alla Nikolajevna S; Edland, Astrid; Eikeland, Randi; Gosal, Sonia; Harbo, Hanne Flinstad; Kleveland, Grethe; Sørenes, Yvonne; Øksendal, Nina; Bjørnevik, Kjetil Lauvland (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background: Low vitamin D levels, tobacco use and high body mass index (BMI) have been linked to adverse disease outcomes in multiple sclerosis (MS), but their influence on long-term disability progression remains unclear. ...
  • Low Z-4OHtam concentrations are associated with adverse clinical outcome among early stage premenopausal breast cancer patients treated with adjuvant tamoxifen 
    Helland, Thomas; Naume, Bjørn; Hustad, Steinar; Bifulco, Ersilia; Kvaløy, Jan Terje; Sætersdal, Anna Barbro; Synnestvedt, Marit; Lende, Tone Hoel; Gilje, Bjørnar; Mjaaland, Ingvil; Weyde, Kjetil; Blix, Egil Støre; Wiedswang, Gro; Borgen, Elin; Hertz, Daniel Louis; Janssen, Emiel; Mellgren, Gunnar; Søiland, Håvard (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract Low steady‐state levels of active tamoxifen metabolites have been associated with inferior treatment outcomes. In this retrospective analysis of 406 estrogen receptor‐positive breast cancer (BC) patients receiving ...
  • Low β2-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism 
    Braadland, Peder; Grytli, Helene Hartvedt; Ramberg, Håkon Andre; Katz, Betina; Kellmann, Ralf; Gauthier-Landry, louis; Fazli, Ladan; Krobert, Kurt Allen; Wang, Wanzhong; Levy, Finn Olav; Bjartell, Anders; Berge, Viktor; Rennie, Paul S.; Mellgren, Gunnar; Mælandsmo, Gunhild; Svindland, Aud; barbier, olivier; Tasken, Kristin Austlid (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    The underlying mechanisms responsible for the development of castration-resistant prostate cancer (CRPC) in patients who have undergone androgen deprivation therapy are not fully understood. This is the first study to ...
  • Low-dose CT coronary angiography for assessment of coronary artery disease in patients with type 2 diabetes - A cross-sectional study 
    Ulimoen, Geir R; Ofstad, Anne P; Endresen, Knut; Gullestad, Lars; Johansen, Odd E; Borthne, Arne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background Silent coronary artery disease (CAD) is prevalent in type 2 diabetes mellitus (T2DM). Although coronary computed tomography angiography (CCTA) over recent years has emerged a useful tool for ...
  • Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk 
    Mitrovic, Mitja; Patsopoulos, Nikolaos A.; Beecham, Ashley H.; Dankowski, Theresa; Goris, An; Dubois, Benedicte; D’hooghe, Marie B.; Lemmens, Robin; Van Damme, Philip; Bach Søndergaard, Helle; Sellebjerg, Finn; Soelberg Sorensen, Per; Ullum, Henrik; Thørner, Lise Wegner; Werge, Thomas; Saarela, Janna; Cournu-Rebeix, Isabelle; Damotte, Vincent; Fontaine, Bertrand; Guillot-Noel, Lena; Lathrop, Mark; Vukusik, Sandra; Gourraud, Pierre-Antoine; Andlauer, Till F.M.; Pongratz, Viola; Buck, Dorothea; Gasperi, Christiane; Antonios, Bayas; Heesen, Christoph; Kümpfel, Tania; Linker, Ralf; Paul, Friedemann; Stangel, Martin; Tackenberg, Björn; Bergh, Florian Then; Warnke, Clemens; Wiendl, Heinz; Wildemann, Brigitte; Zettl, Uwe; Ziemann, Ulf; Tumani, Hayrettin; Gold, Ralf; Grummel, Verena; Hemmer, Bernhard; Knier, Benjamin; Lill, Christina M.; Myhr, Kjell-Morten; Celius, Elisabeth Gulowsen; Lie, Benedicte Alexandra; Cotsapas, Chris (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Multiple sclerosis is a complex neurological disease, with ∼20% of risk heritability attributable to common genetic variants, including >230 identified by genome-wide association studies. Multiple strands of evidence suggest ...
  • Low-Input RNA-Sequencing in Patients with Cartilage Lesions, Osteoarthritis, and Healthy Cartilage 
    Wang, Katherine; Esbensen, Qin Ying; Karlsen, Tommy Aleksander; Eftang, Cathrine Nørstad; Owesen, Christian; Årøen, Asbjørn; Jakobsen, Rune Bruhn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Objective: To analyze and compare cartilage samples from 3 groups of patients utilizing low-input RNA-sequencing. Design: Cartilage biopsies were collected from patients in 3 groups (n = 48): Cartilage lesion (CL) patients ...
  • Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness 
    Andreou, Dimitrios; Steen, Nils Eiel; Jørgensen, Kjetil Nordbø; Smelror, Runar Elle; Wedervang-Resell, Kirsten; Nerland, Stener; Westlye, Lars Tjelta; Nærland, Terje; Myhre, Anne Margrethe; Joa, Inge; Reitan, Solveig Merete Klæbo; Vaaler, Arne; Morken, Gunnar; Bøen, Erlend; Elvsåshagen, Torbjørn; Boye, Birgitte; Malt, Ulrik Fredrik; Aukrust, Pål; Skrede, Silje; Kroken, Rune Andreas; Johnsen, Erik; Djurovic, Srdjan; Andreassen, Ole; Ueland, Thor; Agartz, Ingrid (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background Both neurodegenerative and neurodevelopmental abnormalities have been suggested to be part of the etiopathology of severe mental illness (SMI). Neuron-specific enolase (NSE), mainly located in the neuronal ...
  • Lower Extremity Intermittent Negative Pressure for Intermittent Claudication. Follow-Up after 24 Weeks of Treatment 
    Hoel, Henrik; Pettersen, Erik Mulder; Høiseth, Lars Øivind; Mathiesen, Iacob; Seternes, Arne; Hisdal, Jonny (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Background Treatment with lower extremity intermittent negative pressure (INP) of -40 mm Hg for one hour twice daily for 12 weeks, increases walking capacity in patients with intermittent claudication (IC). However, the ...
  • Lower iron stores were associated with suboptimal gross motor scores in infants at 3–7 months 
    Ljungblad, Ulf Wike; Tangeraas, Trine; Paulsen, Henriette; Lindberg, Morten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Aim: To investigate associations between iron status and gross motor scores in infants aged 3–7 months.Methods: In a prospective study, 252 infants aged 3–7 months were examined using the age-standardised Alberta Infant ...
  • Lower Limb Oedema in Patients with Proximal Femoral Fracture : A study of pathogenetic mechanisms 
    Kazmi, Syed Sajid Hussain (Doctoral thesis / Doktoravhandling, 2010)
  • Lower plasma total tau in adolescent psychosis: Involvement of the orbitofrontal cortex 
    Andreou, Dimitrios; Jørgensen, Kjetil Nordbø; Nerland, Stener; Smelror, Runar; Wedervang-Resell, Kirsten; Johannessen, Cecilie Haggag; Myhre, Anne Margrethe; Andreassen, Ole; Blennow, Kaj; Zetterberg, Henrik; Agartz, Ingrid (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Schizophrenia is thought to be a neurodevelopmental disorder with neuronal migration, differentiation and maturation disturbances. Tau is a microtubule-associated protein with a crucial role in these processes. Lower ...
  • Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and its Risk Factors: Evidence From a Genome-Wide Association Meta-Analysis Followed by Mendelian Randomization 
    Zheng, Jie; Wheeler, Eleanor; Pietzner, Maik; Andlauer, Till F.M.; Yau, Michelle S.; Hartley, April E.; Brumpton, Ben Michael; Rasheed, Humaira; Kemp, John P.; Frysz, Monika; Robinson, Jamie; Reppe, Sjur; Prijatelj, Vid; Gautvik, Kaare M; Falk, Louise; Maerz, Winfried; Gergei, Ingrid; Peyser, Patricia A; Kavousi, Maryam; de Vries, Paul S.; Miller, Clint L.; Bos, Maxime; Van Der Laan, Sander W.; Malhotra, Rajeev; Herrmann, Markus; Scharnagl, Hubert; Kleber, Marcus; Dedoussis, George; Zeggini, Eleftheria; Nethander, Maria; Ohlsson, Claes; Lorentzon, Mattias; Wareham, Nick; Langenberg, Claudia; Holmes, Michael V.; Smith, George Davey; Tobias, Jonathan H. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Objective In this study, we aimed to establish the causal effects of lowering sclerostin, target of the antiosteoporosis drug romosozumab, on atherosclerosis and its risk factors. Methods A genome-wide association ...
  • LRG1 as a non-invasive biomarker for improved precision in prostate cancer assessment 
    Guldvik, Ingrid Jenny (Doctoral thesis / Doktoravhandling, 2023)
    More than 5000 men are diagnosed with prostate cancer each year in Norway. There is a high frequency of indolent disease and a challenge to identify patients with the aggressive phenotype. This causes a significant proportion ...
  • Lugol's solution and Gentian violet eradicate methicillin-resistant Staphylococcus aureus biofilm in skin wound infections 
    Grønseth, Torstein; Ovchinnikov, Kirill; Carlsen, Harald; Saltyte Benth, Jurate; Diep, Dzung B.; Von Unge, Magnus; Silvola, Juha Tapio (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    The study aimed to evaluate the antibacterial efficacy of Lugol's solution 5% and Gentian violet 1% against methicillin-resistant Staphylococcus aureus (MRSA) biofilm in vivo. The bactericidal efficacy for treatment of ...
  • Lugol's solution eradicates Staphylococcus aureus biofilm in vitro 
    Grønseth, Torstein; Vestby, Lene Karine; Nesse, Live Lingaas; Thoen, Even; Habimana, Olivier; Von Unge, Magnus; Silvola, Juha Tapio (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Objectives: The aim of the study was to evaluate the antibacterial efficacy of Lugol's solution, acetic acid, and boric acid against Staphylococcus aureus biofilm. Methods: The efficacy of Lugol's solution 1%, 0.1%, and ...
  • Lumbar spine surgery across 15 years: Trends, complications and reoperations in a longitudinal observational study from Norway 
    Grotle, Margreth; Småstuen, Milada Cvancarova; Fjeld, Olaf Randall; Grøvle, Lars; Helgeland, Jon; Storheim, Kjersti; Solberg, Tore; Zwart, John-Anker (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Studies from different Western countries have reported a rapid increase in spinal surgery rates, an increase that exceeds by far the growing incidence rates of spinal disorders in the general population. There ...
  • Lumican accumulates with fibrillar collagen in fibrosis in hypertrophic cardiomyopathy 
    Rixon, Chloe Louise; Andreassen, Kristine; Shen, Xin; Murugan Erusappan, Pugazendhi; Almaas, Vibeke Marie; Palmero, Sheryl; Dahl, Christen Peder; Ueland, Thor; Sjaastad, Ivar; Louch, William Edward; Stokke, Mathis Korseberg; Tønnessen, Theis; Christensen, Geir; Lunde, Ida Gjervold (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Aims Familial hypertrophic cardiomyopathy (HCM) is the most common form of inherited cardiac disease. It is characterized by myocardial hypertrophy and diastolic dysfunction, and can lead to severe heart failure, ...