Browsing Institutt for klinisk medisin by Title
Now showing items 4440-4459 of 10728
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Introduction Hepatitis E virus (HEV) is a leading cause of acute viral hepatitis in the developing world and is a public health problem, in particular among pregnant women, where it may lead to severe or fatal complications. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Many high-throughput sequencing datasets can be represented as objects with coordinates along a reference genome. Currently, biological investigations often involve a large number of such datasets, for example representing ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Aims To explore whether the general practitioners’ (GPs’) performance of recommended processes of care was associated with estimated risk of cardiovascular disease (CVD) and poor glycaemic control in patients with type ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Circulating microvesicles (cMV) are small phospholipid-rich blebs shed from the membrane of activated vascular cells that contribute to vascular disease progression. We aimed to investigate whether the quality of the Nordic ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Purpose The effect of high arterial oxygen levels and supplemental oxygen administration on outcomes in traumatic brain injury (TBI) is debated, and data from large cohorts of TBI patients are limited. We investigated ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased. Abstract Objective To investigate ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Abstract Background Immune dysregulation is a major factor in the development of severe coronavirus disease 2019 (COVID-19). The homeostatic chemokines CCL19 and CCL21 have been implicated ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background The prevalence and clinical implications of genetic heterogeneity in patients with multiple colorectal liver metastases remain largely unknown. In a prospective series of patients undergoing resection of ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background Strict adherence to a gluten-free diet usually leads to clinical and histological remission in celiac disease. Few studies have investigated the prevalence of persistent symptoms in a celiac population. We ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)In primary prostate cancer, the common multifocality and heterogeneity are major obstacles in finding robust prognostic tissue biomarkers. The long noncoding RNA SCHLAP1 has been suggested, but its prognostic value has not ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Background Vulvar squamous cell carcinoma is a cancer form with increasing incidence rate and few treatment options. Wee1 is a central regulator of the G2/M DNA-damage checkpoint, and has in previous studies ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background and purpose — The treatment of patients between 55 and 70 years with displaced intracapsular femoral neck fracture remains controversial. We compared internal fixation (IF), bipolar hemiarthroplasty (HA) and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)As major depression (MD) is often comorbid with alcohol-use disorders (AUD) and alcohol itself modulates the immune system, we examined serum levels of interleukin (IL)-6, IL-10, tumor necrosis factor (TNF), and interferon ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)VTI1A-TCF7L2 was reported as a recurrent fusion gene in colorectal cancer (CRC), found to be expressed in three out of 97 primary cancers, and one cell line, NCI-H508, where a genomic deletion joins the two genes [1]. To ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)The frequency of late in-the-bag intraocular lens (IOL) dislocation has increased over the past decades. Important predisposing factors are pseudoexfoliation syndrome (PXF), myopia, previous vitreoretinal surgery, and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Background Following curative-intent neoadjuvant therapy in locally advanced rectal cancer, metastatic progression is still dominant. We investigated if patients’ circulating 25-hydroxyvitamin D [25(OH)D] ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Aim Long non-coding RNA (lncRNA) is currently considered to play an important regulatory role in various diseases, including tumors, at present a hot topic in research. As a non-coding transcription product of imprinted ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Objective Inflammation has emerged as a new treatment target in patients with coronary artery disease and inflammation seems to play an important role in ischaemia/reperfusion injury that follows ST-elevation myocardial ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Purpose: The purpose of this study was to examine why Norway has the highest rate of mortality due to cutaneous melanoma (CM) in Europe. The Norwegian Malignant Melanoma Registry (NMMR) enables the study of clinical and ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background The host response to intruders in the central nervous system (CNS) may be beneficial but could also be harmful and responsible for neurologic symptoms and sequelae in CNS infections. This immune ...