Browsing Institutt for klinisk medisin by Title

Now showing items 4310-4329 of 10751

  • Hair cortisol and self-perceived stress in adolescents with multi-system functional somatic disorders 
    Nyengaard, Rebecca; Kallesøe, Karen H.; Rimvall, Martin K.; Ørnbøl, Eva; Wellnitz, Kaare B.; Olsen, Else M.; Wyller, Vegard B. B.; Rask, Charlotte U. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
    Background Long-term stress causing altered hypothalamic–pituitary–adrenal (HPA) axis dynamics with cortisol dysfunction may be involved in the pathophysiology of functional somatic disorders (FSD), but ...
  • Half-life extension of efficiently produced DARPin serum albumin fusions as a function of FcRn affinity and recycling 
    Merten, Hannes; Brandl, Fabian; Zimmermann, Martina; Schaefer, Jonas V.; Irpinio, Linda; Sand, Kine M.K.; Nilsen, Jeannette; Andersen, Jan Terje; Zangemeister-Wittke, Uwe; Plückthun, Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Serum albumin shows slow clearance from circulation due to neonatal Fc receptor (FcRn)-mediated recycling and has been used for half-life extension. We report here fusions to a high-affinity DARPin, binding to Epithelial ...
  • Hallmarks of postoperative liver regeneration: An updated insight on the regulatory mechanisms 
    Shi, Jihua; Line, Pål Dag (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Performance and advances in liver surgery makes remarkable progress of the understanding of liver regeneration. Liver regeneration after liver resection has been widely researched, and the underlying mechanism mostly ...
  • Hallucinations in healthy older adults: An overview of the literature and perspectives for future research 
    Badcock, Johanna C.; Dehon, Hedwige; Larøi, Frank (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    KEY POINTS Studies suggest a substantial minority of healthy older adults have hallucinatory experiences, in line with existing evidence on hallucinations in other age groups, though it is still unclear if hallucination ...
  • Hallucinations in older adults: A practical review 
    Badcock, Johanna C.; Larøi, Frank; Kamp, Karina; Kelsall-Foreman, India; Bucks, Romola S.; Weinborn, Michael; Begemann, Marieke; Taylor, John-Paul; Collerton, Daniel; O'Brien, John T.; El Haj, Mohamad; Ffytche, Dominic; Sommer, Iris Else Clara (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    By 2050, it is estimated that 16% of people will be aged above 65 years, compared with 9% in 2019.1 Population aging is driving increased attention to the physical and mental health needs of older adults. Here, our focus ...
  • Hallucinations under psychedelics and in the schizophrenia spectrum: An interdisciplinary and multiscale comparison 
    Leptourgos, Pantelis; Fortier-Davy, Martin; Carhart-Harris, Robin; Corlett, Philip; Dupuis, David; Halberstadt, Adam L.; Kometer, Michael; Kozakova, Eva; Larøi, Frank; Noorani, Tehseen N.; Preller, Katrin H.; Waters, Flavie; Zaytseva, Yuliya; Jardri, Renaud (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract The recent renaissance of psychedelic science has reignited interest in the similarity of drug-induced experiences to those more commonly observed in psychiatric contexts such as the schizophrenia-spectrum. This ...
  • Halved contrast medium dose in lower limb dual-energy computed tomography angiography—a randomized controlled trial 
    Kristiansen, Cathrine Helgestad; Thomas, Owen Matthew Truscott; Tran, Thien Trung; Roy, Sumit K; Hykkerud, Dan L; Sanderud, Audun; Geitung, Jonn Terje; Lauritzen, Peter Mæhre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Objectives To compare vascular attenuation (VA) of an experimental half iodine-load dual-layer spectral detector CT (SDCT) lower limb computed tomography angiography (CTA) with control (standard ...
  • Hand bone loss as an outcome measure in established rheumatoid arthritis: 2-year observational study comparing cortical and total bone loss 
    Hoff, Mari; Haugeberg, Glenn; Kvien, Tore K (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
    The aim of this 2-year longitudinal observational study was to explore hand bone loss as a disease outcome measure in established rheumatoid arthritis (RA). A cohort of 215 patients with RA (170 women and ...
  • Handling realistic assumptions in hypothesis testing of 3D co-localization of genomic elements 
    Paulsen, Jonas; Lien, Tonje G.; Sandve, Geir Kjetil; Holden, Lars; Borgan, Ørnulf; Glad, Ingrid K.; Hovig, Johannes Eivind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
    The study of chromatin 3D structure has recently gained much focus owing to novel techniques for detecting genome-wide chromatin contacts using next-generation sequencing. A deeper understanding of the architecture of the ...
  • Hands-free continuous carotid Doppler ultrasound for detection of the pulse during cardiac arrest in a porcine model 
    Faldaas, Bjørn Ove; Nielsen, Erik Waage; Storm, Benjamin; Lappegård, Knut Tore; How, Ole-Jakob; Nilsen, Bent Aksel; Kiss, Gabriel Hanssen; Skogvoll, Eirik; Torp, Hans; Ingul, Charlotte Ingeborg Björk (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background/Purpose Pulse palpation is an unreliable method for diagnosing cardiac arrest. To address this limitation, continuous hemodynamic monitoring may be a viable solution. Therefore, we developed a novel, hands-free ...
  • Haploinsufficiency of two histone modifier genes on 6p22.3, ATXN1 and JARID2, is associated with intellectual disability 
    Barøy, Tuva; Misceo, Doriana; Strømme, Petter; Stray-Pedersen, Asbjørg; Holmgren, Asbjørn; Rødningen, Olaug K; Blomhoff, Anne; Helle, Johan R; Stormyr, Alice; Tvedt, Bjørn; Fannemel, Madeleine; Frengen, Eirik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
  • Haptoglobin 2-2 Genotype, Patient, and Graft Survival in Renal Transplant Recipients 
    Dupont, Laust; Eide, Ivar Anders; Hartmann, Anders; Christensen, Jeppe Hagstrup; Åsberg, Anders; Jenssen, Trond Geir; Krarup, Henrik; Svensson, My Hanna Sofia (Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
    Background: Cardiovascular disease is the leading cause of death in renal transplant recipients. An association between haptoglobin genotype 2-2 and cardiovascular disease has been found in patients with diabetes mellitus ...
  • Har svangerskapsavbrudd betydning for nedgangen i antall fødsler? 
    Meinich, Tale Jeanette; Eskild, Anne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    BAKGRUNN Fødselsratene i Norge er fallende, og stadig færre får flere enn to barn. Svangerskapsavbrudd kan påvirke fødselstallene. Vi ønsket å studere fordelingen av graviditeter i Norge etter paritet, og om andelen av ...
  • Harm to Others from Substance Use and Abuse: The Underused Potential in Nationwide Registers 
    Lund, Ingunn Olea; Bukten, Anne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    This article considers the potential in using nationwide registers to study harm to others from substance use and abuse. The advantages of using registry data include the opportunity to include the data on the entire ...
  • Harmful alcohol use among acutely ill hospitalized medical patients in Oslo and Moscow: A cross-sectional study 
    Kabashi, Saranda; Vindenes, Vigdis; Bryun, Eugeniy Alekseevich; Koshkina, Evgenia A.; Nadezhdin, Alexey V.; Tetenova, Elena J.; Kolgashkin, Alexey J.; Petukhov, Alexey E.; Perekhodov, S.N.; Davydova, Erna; Gamboa, Danil; Hilberg, Thor; Lerdal, Anners; Nordby, Gudmund; Zhang, Chi; Bogstrand, Stig Tore (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background The aim was to estimate the prevalence of harmful alcohol use in relation to socio-demographic characteristics among acutely ill medical patients, and examine identification measures of alcohol use, including ...
  • Harmful effects of exercise intensity and exercise duration in patients with arrhythmogenic cardiomyopathy 
    Lie, Øyvind Haugen; Dejgaard, Lars; Saberniak, Jørg; Rootwelt, Christine; Stokke, Mathis Korseberg; Edvardsen, Thor; Haugaa, Kristina (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Objectives The goal of this study was to explore the association between exercise duration versus exercise intensity and adverse outcome in patients with arrhythmogenic cardiomyopathy (AC). Background Vigorous ...
  • Harnessing features of adaptive NK cells to generate iPSC-derived NK cells for enhanced immunotherapy 
    Woan, Karrune V.; Kim, Hansol; Bjordahl, Ryan; Davis, Zachary B.; Gaidarova, Svetlana; Goulding, John; Hancock, Brian; Mahmood, Sajid; Abujarour, Ramzey; Wang, Hongbo; Tuininga, Katie; Zhang, Bin; Wu, Cheng-Ying; Kodal, Behiye; Khaw, Melissa; Bendzick, Laura; Rogers, Paul; Ge, Moyar Qing; Bonello, Greg; Meza, Miguel; Felices, Martin; Huffman, Janel; Dailey, Thomas; Lee, Tom T.; Walcheck, Bruce; Malmberg, Karl-Johan; Balzar, Bruce R.; Bryceson, Yenan; Valamehr, Bahram; Miller, Jeffrey S.; Cichocki, Frank (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
    Select subsets of immune effector cells have the greatest propensity to mediate antitumor responses. However, procuring these subsets is challenging, and cell-based immunotherapy is hampered by limited effector-cell ...
  • Hazardous Drinking Prevalence and Correlates in Older New Zealanders: A Comparison of the AUDIT-C and the CARET 
    Towers, Andy; Szabo, Agnes; Newcombe, David A L; Sheridan, Janie; Moore, Alison; Hyde, Martin; Britton, Annie R.; Martinez, Priscilla; Minicuci, Nadia; Kowal, Paul; Clausen, Thomas; Savage, Christine L (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Objectives: The study compared the proportion of older adults identified as drinking hazardously based on the Alcohol Use Disorders Identification Test–Consumption (AUDIT-C) with the older adult-specific Comorbidity Alcohol ...
  • Hb Aalesund (HBA2: c.400_406delAGCACCG), an Unstable α-Globin Variant Found in a Norwegian Patient Causing Moderate Hemolytic Anemia and Falsely High Hb A1c Using Ion Exchange High Performance Liquid Chromatography. 
    Grimholt, Runa Marie; Fjeld, Bente; Selsås, Hilde; Schwettmann, Lutz; Klingenberg, Olav (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    A new unstable hemoglobin (Hb) variant, named Hb Aalesund, was detected during Hb A1c measurement in a patient with a nearly compensated hemolytic anemia. Sequencing of the α-globin genes revealed a 7 bp deletion in exon ...
  • Hb Calgary (HBB: c.194G>T): A Highly Unstable Hemoglobin Variant with a β-Thalassemia Major Phenotype 
    Georgina, Martin; Grimholt, Runa Marie; Le, Doan; Bechensteen, Anne Grete; Klingenberg, Olav Inge; Fjeld, Bente; Fourie, Thomas; Perrier, Renee; Proven, Melanie; Henderson, Shirley J; Roy, Noémi B A (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
    We describe two unrelated patients, both heterozygous for an unstable hemoglobin (Hb) variant named Hb Calgary (HBB: c.194G>T) that causes severe hemolytic anemia and dyserythorpoietic, resulting in transfusion dependence ...