Browsing Institutt for klinisk medisin by Title
Now showing items 10686-10705 of 10751
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Shiga toxin-producing Escherichia coli, a foodborne bacterial pathogen, has been linked to a broad spectrum of clinical outcomes ranging from asymptomatic carriage to fatal hemolytic uremic syndrome (HUS). Here, we collected ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)Primary immunodeficiency (PID) is characterized by recurrent and often life-threatening infections, autoimmunity and cancer, and it poses major diagnostic and therapeutic challenges. Although the most severe forms of PID ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2015)Shared decision making has become an ideal in contemporary clinical practice, and guidelines recommend exploring patients’ preferences and providing them with options so they can make informed decisions. This paper examines ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Although a significant proportion of adults recover from substance use disorders (SUDs), little is known about how they reach this turning point or why they stop using. The purpose of the study was to explore the factors ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background Russia has one of the highest rates of mortality from cardiovascular disease (CVD). At age 35–69 years, they are eight times higher than in neighbouring Norway. Comparing profiles of blood-based CVD biomarkers ...
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Why Not Dipyridamole: a Review of Current Guidelines and Re-evaluation of Utility in the Modern Era (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)Dipyridamole is an old anti-platelet and coronary vasodilator agent that inhibits platelet phosphodiesterase and increases interstitial adenosine levels. Its use in coronary artery disease (CAD) has fallen out of practice ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Cancer cells can have different patterns of exon usage of individual genes when compared to normal tissue, suggesting that alternative splicing may play a role in shaping the tumor phenotype. The discovery and identification ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background Elucidating the neurobiological effects of sleep and waking remains an important goal of the neurosciences. Recently, animal studies indicated that sleep is important for cell membrane and myelin maintenance in ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background and purpose: Previous experimental studies have shown that meningeal lymphatic vessels are located primarily along the walls of the dural sinus veins. Whether they are more widespread throughout human dura mater ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)Study Objectives To assess white matter involvement in H1N1-vaccinated hypocretin deficient patients with narcolepsy type 1 (NT1) compared with first-degree relatives (a potential risk group) and healthy controls. Me ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)The regional distribution of white matter (WM) abnormalities in schizophrenia remains poorly understood, and reported disease effects on the brain vary widely between studies. In an effort to identify commonalities across ...
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(Doctoral thesis / Doktoravhandling, 2016)This thesis deals with the aspects of monitoring psychotherapy in ordinary psychiatric settings in Norway with the goal of improving the quality of mental health services. The research resulted in three published papers. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Despite great interest in using magnetic resonance imaging (MRI) for studying the effects of genes on brain structure in humans, current approaches have focused almost entirely on predefined regions of interest and had ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)The mammalian Atg18 ortholog WIPI2 is a key regulator of LC3 lipidation to promote autophagosome biogenesis during nonselective macroautophagy, while its functions in selective autophagy such as mitophagy remain largely ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background Gastroparesis is a potentially severe late complication of diabetes mellitus. Today, delayed gastric emptying (GE) is mandatory for establishing the diagnosis. In this study, we compared wireless motility ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)Abstract To evaluate objective time consumption and how nurses perceived introducing wireless patient monitoring (WPM) and a validated score on patient quality and safety, the Efficacy Safety Score (ESS), at a mixed surgery ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Alterations in resting state networks (RSNs) are associated with emotional- and attentional control difficulties in depressed individuals. Attentional bias modification (ABM) training may lead to more adaptive emotional ...
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Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Abstract Estimates from genome-wide association studies (GWAS) of unrelated individuals capture effects of inherited variation (direct effects), demography (population stratification, assortative mating) and relatives ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Human limbal epithelial stem cells (hLESCs) continuously replenish lost or damaged human corneal epithelial cells. The percentage of stem/progenitor cells in autologous ex vivo expanded tissue is essential for the long-term ...