Browsing Institutt for molekylær biovitenskap ( -2012) by Title
Now showing items 264-283 of 343
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(Master thesis / Hovedoppgave, 2007)There is a fine balance between Ag presentation and by the destruction of Ag peptides. In a “Troybody” vaccine design it is of great importance that the introduced epitopes are properly excised from the Ab molecule. Specific ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Background Cyanopeptolins are nonribosomally produced heptapetides showing a highly variable composition. The cyanopeptolin synthetase operon has previously been investigated in three strains from the genera ...
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(Master thesis / Masteroppgave, 2005)Abstract Nuclear receptors that work as heterodimers with RXR control several aspects of lipid metabolism. One such nuclear receptor, pregnane X receptor (PXR) is the molecular target for a wide variety of endogenous and ...
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(Master thesis / Masteroppgave, 2006)A unique characteristic of skeletal muscle is its diversity, reflected in the fibre type composition of muscles and in the heterogeneity of different fibre types. Mammalian skeletal muscle has a remarkable capacity to ...
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(Master thesis / Masteroppgave, 2011)Gb3 (Gal α1-4, Gal β1-4, Glc β1-1, Ceramide) is a neutral glycosphingolipid specifically expressed in several human tissues, and is recognised as a receptor for Shiga toxins. Gb3 has been demonstrated to be upregulated in ...
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(Master thesis / Masteroppgave, 2005)Androgen ablation during the initial stages of prostate cancer causes regression of the tumor due to an increase in apoptosis and reduced cellular proliferation. However, some prostate cancer cells survive in the androgen ...
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(Master thesis / Masteroppgave, 2012)
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Regulation of the gap junction protein connexin43 by members of the Nedd4 E3 ubiquitin ligase familyRestricted Access (Master thesis / Masteroppgave, 2010)
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(Master thesis / Hovedoppgave, 2007)Peroksisom proliferator-aktivert reseptor a (PPARa) har en sentral rolle i regulering av uttrykk av lever-spesifikke gener. Da gallesyrer blir produsert fra kolesterol i leveren, og mange av enzymene involvert i deres ...
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(Master thesis / Masteroppgave, 2008)The crucian carp (Carassius carassius) inhabits lakes and ponds in Northern Europe, where it is able to survive anoxia that often occurs for months during the long winter. Several physiological adaptations, including the ...
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(Master thesis / Masteroppgave, 2012)This study was carried out at the Department of Cell Biology at the Institute of Cancer Research at the Oslo University Hospital as a part of my Master’s degree in molecular biosciences at the University of Oslo. Our group ...
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(Master thesis / Masteroppgave, 2011)In addition to providing morphological support, the actin cytoskeleton is involved in cell motility, endocytosis and intracellular transport. Cytoskeletal interaction with the membrane is an essential part of these processes ...
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(Master thesis / Masteroppgave, 2009)The human HMGA2 gene is located at chromosomal band 12q14-15. In normal cells it encodes for the HMGA2 protein (109 amino acids). HMGA2 is a transcription factor that binds to the AT rich sequences on DNA and thereby ...
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(Master thesis / Masteroppgave, 2008)Animals store most excess energy as fat in specialized cells called adipocytes which form the major part of adipose tissue. Since obesity, which has reached epidemic proportions in the last decades, is the result of excess ...
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(Master thesis / Masteroppgave, 2010)The myogenic regulatory factors (MRFs) are a group of muscle specific transcription factors important during determination and differentiation of muscle fibers. In adult muscle two of the members, MyoD and myogenin, are ...
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Role of pro-inflammatory cytokines in persistent pain after disc herniation : nociceptive signaling and genetic susceptibilityRestricted Access (Master thesis / Masteroppgave, 2012)Low back pain and sciatica after disc herniation may be caused by mechanical compression of the nerve roots, but also by the release of inflammatory substances from nucleus pulposus (NP) of the herniated disc. In the present ...
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The Role of SNX8 in Retrograde Transport of Shiga Toxin : SNX8 facilitated transport of Shiga toxin is regulated by PKCdelta and p38alfaRestricted Access (Master thesis / Masteroppgave, 2010)Sorting nexin 8 (SNX8) belongs to the sorting nexin protein family. Members of this family are known to be involved in endocytosis and endosomal sorting. It was recently reported that SNX8 regulates retrograde transport ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Background Lepeophtheirus salmonis is an ectoparasitic copepod feeding on skin, mucus and blood from salmonid hosts. Initial analysis of EST sequences from pre adult and adult stages of L. salmonis revealed ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)Background The transcription factor c-Myb is expressed in hematopoietic progenitor cells and other rapidly proliferating tissues, regulating genes important for proliferation, differentiation and survival. ...
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(Doctoral thesis / Doktoravhandling, 2012)