Browsing Institutt for molekylær biovitenskap ( -2012) by Title
Now showing items 201-220 of 343
-
Ligand-receptor matchmaking: Signaling of the IDL proteins through the LRR-RLKs of the HAESA family (Master thesis / Masteroppgave, 2009)
-
Ligand-receptor matchmaking: The IDA-HAE/HSL2 signaling system and the IDL and HSL relativesRestricted Access (Master thesis / Masteroppgave, 2009)Until recently, most intercellular communication in plants has been explained by the signaling and perception of non-peptide plant hormones. It is, however, becoming increasingly clear that plant cell communication also ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Aldehyde dehydrogenase (ALDH) has recently been shown to be a marker of cancer stem-like cells (CSCs) across tumour types. The primary goals of this study were to investigate whether ALDH is expressed in liposarcomas, and ...
-
(Master thesis / Hovedoppgave, 2004)Glutamat er kvantitativt den dominerende eksitatoriske nevrotransmitteren i sentralnervesystemet (CNS) hos pattedyr, og er sannsynligvis involvert i de fleste aspekter ved normal hjernefunksjon, inkludert hukommelse og ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)Background Microarray-based comparative genomic hybridisation (array CGH) is a technique by which variation in relative copy numbers between two genomes can be analysed by competitive hybridisation to DNA ...
-
(Master thesis / Hovedoppgave, 2004)Neurofibromatosis type 1 (NF1) is one of the most common autosomal dominant inherited disorders, and carriers are at greatly increased risk of developing malignant peripheral nerve sheath tumours (MPNST). The NF1 patients ...
-
(Master thesis / Masteroppgave, 2007)Amplification of several regions of chromosome 8q is frequently detected in breast tumors, and several genes located on this chromosome arm show increased expression in the tumors. One of these genes encodes ã-glutamyl ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)Background Amplification of the q21-q23 region on chromosome 1 is frequently found in sarcomas and a variety of other solid tumours. Previous analyses of sarcomas have indicated the presence of at least ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)Background Photodynamic therapy (PDT) involves systemic or topical administration of a lesion-localizing photosensitizer or its precursor, followed by irradiation of visible light to cause singlet ...
-
(Master thesis / Masteroppgave, 2009)Malignant melanoma is a very metastatic and therapy resistant disease, with few therapeutic options in advanced stages. An abnormal apoptosis pathway is considered to contribute substantially to the resistance observed in ...
-
MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Frequent failure and severe side effects of current sarcoma therapy warrants new therapeutic approaches. The small-molecule MDM2 antagonist Nutlin-3a activates the p53 pathway and efficiently ...
-
(Doctoral thesis / Doktoravhandling, 2008)Ricin and Shiga toxin are protein toxins able to enter target cells by endocytosis. They can be transported via early endosomes to the Golgi apparatus and the endoplasmic reticulum. From this compartment, they are translocated ...
-
(Master thesis / Masteroppgave, 2007)Newly synthesised proteins are therefore subjected to a strict control machinery in the ER lumen where different chaperones facilitate folding during and after translocation. If the folding process is incomplete, misfolded ...
-
(Master thesis / Hovedoppgave, 2003)In mammalian cells essential polyunsaturated fatty acids (PUFAs) are converted to longer PUFAs by alternating steps of elongation and desaturation. In contrast to other PUFA-rich tissues, the testis is continuously drained ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background Pockmarks (depressions in the seabed) have been discovered throughout the world’s oceans and are often related to hydrocarbon seepage. Although high concentrations of pockmarks are present in ...
-
(Doctoral thesis / Doktoravhandling, 2011)
-
(Master thesis / Masteroppgave, 2006)Radiation is a common treatment of cancer. It can be used either as the primary therapy or as an adjuvant treatment. The objective of radiation therapy is to kill the cancer cells, while minimizing the damage on normal ...
-
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)Background Due to the increased use of genetic modifications in crop improvement, there is a need to develop effective methods for the detection of both known and unknown transgene constructs in plants. We ...
-
(Doctoral thesis / Doktoravhandling, 2007)The goal of the present work was to develop a microchip for amplification and detection of mRNA by employing nucleic acid sequence-based amplification (NASBA) technology. The technology platform should in principle be ...
-
Molecular and genetic analysis of novel genes involved in imprinting in seed developmentRestricted Access (Master thesis / Masteroppgave, 2010)A cluster of genes in both animals and flowering plants are expressed only from one of the two homologous chromosomes, depending upon whether they are maternally or paternally inherited. This phenomenon is called imprinting, ...