Browsing Institutt for molekylær biovitenskap ( -2012) by Title
Now showing items 160-179 of 343
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(Master thesis / Masteroppgave, 2005)Chromatin modulating proteins are thought to be involved in multimeric protein-protein interactions and contain characteristic amino-acid motifs like the SET domain. The SET domain proteins are believed to regulate gene ...
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(Master thesis / Masteroppgave, 2005)Prostate cancer (PCa) and obesity are currently two of the most prevalent health problems in the western world. Some epidemiological studies suggest a connection between PCa and fat intake and obesity. In addition, androgens, ...
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(Master thesis / Hovedoppgave, 2003)Key words: Mucosal targeting, pIgR, Phage display, Automation, Amino acid substitution, Mutation analysis, GFP-fusion protein. 1. Abstract Delivery of therapeutic macromolecules, gene therapy vectors and diagnostics ...
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(Master thesis / Masteroppgave, 2007)Unique to the lifecycle of plant is the existence of a multicellular haploid gametophyte generation. Elucidation of the genetic makeup of gametophyte development and function is important for several reasons. This phase ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)FcγRIIA is a key activating receptor linking immune complex formation with cellular effector functions. FcγRIIA has 93% identity with an inhibitory receptor, FcγRIIB, which negatively regulates FcγRIIA. FcγRIIA is important ...
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(Master thesis / Masteroppgave, 2012)The small GTPase Rab7b is localized to late endosomes and lysosomes and to the Golgi apparatus, and regulates the intracellular transport from late endosomal compartments to the Golgi. However, not much is known about ...
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Identification of cancer-specific transcripts by computational analysis of genome-scale expression data at exon resolutionRestricted Access (Master thesis / Masteroppgave, 2011)Fusion genes have key roles in the development and progression of many human cancers. Detection of oncogenic fusion genes is already implemented in routine diagnostics and fusion proteins are targets in molecularly tailored ...
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(Master thesis / Masteroppgave, 2005)Abstract Vascular endothelial cells contain typical, elongated vesicles called Weibel-Palade bodies (WPBs), which serve as a storage compartment for biologically active factors involved in hemostasis and inflammation. ...
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(Master thesis / Masteroppgave, 2008)Colorectal cancer is a common malignancy that develops over a long period of time. Most cases are sporadic, while a small percentage is hereditary, such as hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome). ...
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Identification of small molecule inhibitors of the transcription factor c-Myb through structure-based drug design and EMSA analysisRestricted Access (Master thesis / Masteroppgave, 2009)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Background Surface proteins are a key to a deeper understanding of the behaviour of Gram-positive bacteria interacting with the human gastro-intestinal tract. Such proteins contribute to cell wall synthesis ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Background The HMGA2 gene, coding for an architectural transcription factor involved in mesenchymal embryogenesis, is frequently deranged by translocation and/or amplification in mesenchymal tumours, generally ...
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Identifisering av interaksjonspartnere til den SUMO-spesifikke proteasen SENP1, ansvarlig for økt genaktivering gjennom deSUMOyleringRestricted Access (Master thesis / Masteroppgave, 2012)
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(Master thesis / Masteroppgave, 2011)
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In vitro ekspresjonssystem for produksjon av bakteriosiner og immunitets proteinerRestricted Access (Master thesis / Masteroppgave, 2012)The structures of the immunity proteins for the two-peptide bacteriocins have not been determined, although knowledge of these structures is of great interest as it may reveal at a molecular level how these proteins render ...
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(Master thesis / Masteroppgave, 2007)Human bone marrow multipotent mesenchymal stromal cells (hBM-MSC) represent an appealing source of adult stem cells for cell therapy and tissue engineering. Since hBM-MSC are present at low frequency in the bone marrow, ...
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(Master thesis / Masteroppgave, 2007)Identifikasjonen av proteinet hNCU-G1 er basert på interaksjonen med hCRBP1-promoterens FP1-element (+66-+99), som ble gjort ved EMSA-studier. Videre studier avslørte at hNCU-G1 kunne fungere som en transkripsjonsfaktor ...
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(Master thesis / Masteroppgave, 2005)Abstract Increased pain response following injury is an important step in the process of protecting the injured site from further damage. However, pain can often be a more serious problem than the injury or disease process ...
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(Master thesis / Hovedoppgave, 2004)Fibroblast growth factors and the four related high-affinity, tyrosine kinase fibroblast growth factor receptors are involved in the regulation of many key cellular responses in developmental and physiological processes. ...
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(Master thesis / Masteroppgave, 2011)The invariant chain (Ii) has for many years been known to have important functions in MHC class II antigen presentation. There are four isoforms of Ii in humans: Iip33, Iip35, Iip41 and Iip43. The two shorter isoforms ...