Browsing Institutt for molekylær biovitenskap ( -2012) by Title
Now showing items 96-115 of 343
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(Master thesis / Masteroppgave, 2006)It has previously been found that the sequence and conformation of a 10-nucleotide element in the 5´untranslated region (5´UTR) of rbcL mRNA are important for transcript stability. In this study two variants of a 20-nucleotide ...
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(Master thesis / Masteroppgave, 2008)The gram-negative bacterium Neisseria gonorrhoeae utilizes an O-linked glycosylation system to decorate a selected set of its proteins. So far however, no glycosylation associated phenotypes have been detected. The most ...
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(Master thesis / Hovedoppgave, 2005)ABSTRACT rbcL is a constitutively expressed gene in the Chlamydomonas chloroplast. The 5 untranslated region (5 UTR) is predicted to form an RNA secondary structure that might function in RNA stabilization. Earlier studies ...
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(Master thesis / Masteroppgave, 2007)Most vertebrates depend on an uninterrupted supply of oxygen to maintain the energy production. Some species, like the crucian carp (Carassius carassius) can survive hypoxia for an extended period. This fish is an expert ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2003)Background A limiting factor of cDNA microarray technology is the need for a substantial amount of RNA per labeling reaction. Thus, 20–200 micro-grams total RNA or 0.5–2 micro-grams poly (A) RNA is typically ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background Previous studies have noted that drug targets appear to be associated with higher-degree or higher-centrality proteins in interaction networks. These studies explicitly or tacitly make choices ...
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(Master thesis / Masteroppgave, 2009)Mechanical factors are important in the regulation of muscle phenotype. Adaptation of structural and mechanical proteins to withstand increased load and cope with increased work is needed in a muscle exposed to mechanical ...
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(Master thesis / Masteroppgave, 2009)In mammals, adult neurogenesis is a restricted phenomenon, taking place in only two distinct areas of the brain, the subventricular zones and the hippocampus. The rate of adult neurogenesis can be regulated through a ...
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(Doctoral thesis / Doktoravhandling, 2008)Cancer cells are growing without control and it is therefore important to understand the mechanisms limiting the growth of normal cells. Before a cell can divide it must make a new set of chromosomes, so that both ...
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(Master thesis / Masteroppgave, 2010)The effects of VEGF on skeletal muscle phenotype in adult rats. Skeletal muscle has an exceptional ability to adapt to different usage. Phenotype transformation is mainly dependent on the changes of firing pattern from ...
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(Master thesis / Masteroppgave, 2011)
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(Master thesis / Masteroppgave, 2011)Vitamin D har en potensiell anti-angiogenetisk effekt ved binding av 1,25 dihydroksyvitmin D3 til VDR (vitamin D reseptoren). VDR er en ligand-aktivert transkripsjonsfaktor som binder til VDRE (vitamin D responselementer) ...
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(Master thesis / Hovedoppgave, 2005)Perfluoro oktansyre (PFOA) er en peroksisomal proliferator som er kjent for å også gi antiinflammatoriske reaksjoner. Virkningsmekanismen for stoffet i levende dyr er lite kjent. For å få en bedre forståelse av PFOAs ...
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(Master thesis / Hovedoppgave, 2002)Abstract The function of ribonucleotide reductase (RNR) is to convert the four normal ribonucleotides to the corresponding deoxynucleotides. In RNR from mouse the enzyme consists of two non-identical dimers called R1 and ...
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(Master thesis / Masteroppgave, 2005)Covalent modifications of the DNA and histones through acetylation, phosphorylation, methylation, etc are central to gene regulation, recombination, DNA replication and many other processes in the cell. With respect to ...
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(Master thesis / Hovedoppgave, 2003)The antimicrobial peptide, sakP(N24C + 44C) is a mutant of a class IIa bacteriocin, sakacin P, produced by lactic acid bacteria. SakP(N24C + 44C) consists of 44 residues and possesses a C-terminal disulphide bond that ...
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(Master thesis / Hovedoppgave, 2005)De to formene av den polymorfe ciliaten Tetrahymena vorax er svært ulike med hensyn på morfologi, atferd og næringspreferanser. Den mikrostome formen lever av blant annet bakterier og råtnende biologisk materiale som taes ...
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(Doctoral thesis / Doktoravhandling, 2009)The plant toxin ricin and the bacterial toxin Shiga toxin are not only a threat to human health but may also be used in cancer treatment and to gain new insight into the mechanisms of intracellular transport. Ricin and ...
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Endosomal Maturation Is Controlled By A Rab7 Feedback Loop Concomitant With Vesicular Interactions (Master thesis / Masteroppgave, 2012)Endosomal maturation controls trafficking and degradation of macromolecules in eukaryotic cells and represents an important regulatory point in the endocytic pathway. Progression through this phase is primarily recognized ...
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Engineering to improve serum half-life modulates classical Fcgamma receptor bindingRestricted Access (Master thesis / Masteroppgave, 2012)Summary Antibodies act as adapter molecules that link recognition of foreign substances, such as bacteria and viruses, to elimination mechanisms mediated by cells and molecules of the innate immune system. Cells that express ...