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(Master thesis / Hovedoppgave, 2004)Neurofibromatosis type 1 (NF1) is one of the most common autosomal dominant inherited disorders, and carriers are at greatly increased risk of developing malignant peripheral nerve sheath tumours (MPNST). The NF1 patients ...
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(Master thesis / Masteroppgave, 2007)Amplification of several regions of chromosome 8q is frequently detected in breast tumors, and several genes located on this chromosome arm show increased expression in the tumors. One of these genes encodes ã-glutamyl ...
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(Master thesis / Masteroppgave, 2009)Malignant melanoma is a very metastatic and therapy resistant disease, with few therapeutic options in advanced stages. An abnormal apoptosis pathway is considered to contribute substantially to the resistance observed in ...
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(Master thesis / Masteroppgave, 2007)Newly synthesised proteins are therefore subjected to a strict control machinery in the ER lumen where different chaperones facilitate folding during and after translocation. If the folding process is incomplete, misfolded ...
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(Master thesis / Hovedoppgave, 2003)In mammalian cells essential polyunsaturated fatty acids (PUFAs) are converted to longer PUFAs by alternating steps of elongation and desaturation. In contrast to other PUFA-rich tissues, the testis is continuously drained ...
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(Master thesis / Masteroppgave, 2006)Radiation is a common treatment of cancer. It can be used either as the primary therapy or as an adjuvant treatment. The objective of radiation therapy is to kill the cancer cells, while minimizing the damage on normal ...
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Molecular and genetic analysis of the MADS-box Type I transcription factors AGAMOUS-LIKE 28 and AGAMOUS-LIKE 36Begrenset tilgang (Master thesis / Masteroppgave, 2011)Abstract Seed development requires a coordinated interplay between different transcriptional programs in the embryo, the endosperm and the maternally derived seed coat. In angiosperms, the embryo and the endosperm are ...
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(Master thesis / Masteroppgave, 2008)Crucian carp (Carassius carassius) avoids lactic acidosis during prolonged periods of anoxia by producing ethanol as the main anaerobic end-product. Apparently, this is made possible by adaptations in the pyruvate dehydrogenase ...
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(Master thesis / Masteroppgave, 2011)
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(Master thesis / Masteroppgave, 2007)A central question in biology is how cells in multi-cellular organisms communicate. During the development of the organisms, each single cell needs to know their exact position and function, and cell-cell signaling is ...
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(Master thesis / Masteroppgave, 2006)The elongation step of transcription is now recognized as a critical target for transcription regulation. An increasing number of elongation factors have been identified, and the regulatory mechanism of elongation seems ...
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(Master thesis / Hovedoppgave, 2003)Sammendrag Alle levende organismer inneholder en eller flere DNA polymeraser, og dette enzymet er helt nødvendig for videreføring av arvestoffet fra generasjon til generasjon. DNA- polymeraser har også etter hvert fått ...
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The nitric oxide synthase protein system in Bacillus cereus : From gene to 3D structureBegrenset tilgang (Master thesis / Masteroppgave, 2012)
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Odorant-specific endocytosis : Mapping the connectivity within the olfactory system in crucian carp, Carassius carassiusBegrenset tilgang (Master thesis / Masteroppgave, 2011)
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(Doctoral thesis / Doktoravhandling, 2008)Hvordan fiskene lukter sex og fare Fisker har en meget god luktesans og bruker den blant annet til å oppfatte farer, for eksempel når andre individer blir skadet eller spist av rovfisk. Noen av substansene fra fiskenes ...
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Optimization of a cell free protein synthesis system for expression of Lactococcin A immunity proteinBegrenset tilgang (Master thesis / Masteroppgave, 2012)
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Osteogenic differentiation of mesenchymal stem cells : Identification of potential regulatorsBegrenset tilgang (Master thesis / Masteroppgave, 2011)Osteogenic differentiation of mesenchymal stem cells (MSC) is a tightly regulated process, inducing large changes in cell phenotype and gene expression. Characterization of these expressional changes may be important in ...
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(Master thesis / Hovedoppgave, 2004)In contrast to the mammalian major histocompatibility complex (MHC), where the MHC class I and class II loci reside in close vicinity to one another, the bony fishes have unlinked MHC class I and class II. Previous studies ...
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(Master thesis / Masteroppgave, 2005)The protein toxin ricin is found in the plant Ricinus communis, and is a useful tool in studies of intracellular traffic. It consists of an enzymatically active A chain and a B chain with lectin properties, joined together ...
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(Master thesis / Masteroppgave, 2006)Cancer is a disease resulting from an accumulation of acquired genetic mutations. The consequence is an uncontrolled growth of cells and disruption of normal control mechanisms. Complex chromosomal aberrations such as ...