Browsing Det medisinske fakultet by Title
Now showing items 574-593 of 598
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)BAKGRUNN Nasjonalt pasientforløp (tidligere kalt pakkeforløp) for oppfølging etter rusmiddeloverdose er en viktig del av nasjonal overdosestrategi og trådte i kraft 1. januar 2022. Fire år forut for dette ble det innledet ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Depletion of the Anaphase-Promoting Complex/Cyclosome (APC/C) activator Cdc20 arrests cells in metaphase with high levels of the mitotic cyclin (Cyclin B) and the Separase inhibitor Securin. In mammalian cells this arrest ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Introduction Antimicrobial resistance (AMR) has a critical global impact, mostly affecting low- and middle-income countries. A major knowledge gap exists in understanding the transmission pathway of the gut colonisation ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background Transcription factors (TFs) bind specifically to TF binding sites (TFBSs) at cis-regulatory regions to control transcription. It is critical to locate these TF-DNA interactions to understand ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Upon the first publication of the fifth iteration of the Functional Annotation of Mammalian Genomes collaborative project, FANTOM5, we gathered a series of primary data and database systems into the FANTOM web resource ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Blood formation, or haematopoiesis, originates from haematopoietic stem cells (HSCs), whose functions and maintenance are regulated in both cell- and cell non-autonomous ways. The surroundings of HSCs in the bone marrow ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Abstract Purpose: PNOC003 is a multicenter precision medicine trial for children and young adults with newly diagnosed diffuse intrinsic pontine glioma (DIPG). ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)Background There is a huge effort in developing ligand-mediated targeting of nanoparticles to diseased cells and tissue. The plant toxin ricin has been shown to enter cells by utilizing both dynamin-dependent ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background: Drugs commonly prescribed for heart rate control may induce adverse drug reactions in Alzheimer patients treated with acetylcholinesterase inhibitors (AChEIs). We have studied use of drugs with a known risk of ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)AIMS OF THE STUDY: Anaphylaxis is a medical emergency and requires prompt treatment to prevent life-threatening conditions. Epinephrine, considered as the first-line drug, is often not administered. We aimed first to analyse ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background. Despite robust evidence from randomized controlled trials (RCTs) demonstrating clinical and patient-reported benefits of integrated oncology and palliative care, the tumour-centred focus is predominant. This ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)Production of soluble proteins is essential for structure/function studies; however, this usually requires milligram amounts of protein, which can be difficult to obtain with traditional expression systems. Recently, the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background As antibiotic resistance creates a significant global health threat, we need not only to accelerate the development of novel antibiotics but also to develop better treatment strategies using existing drugs ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Complexity of lung microenvironment and changes in cellular composition during disease make it exceptionally hard to understand molecular mechanisms driving development of chronic lung diseases. Although recent advances ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Purpose Contemporary trauma resuscitation prioritizes control of bleeding and uses major haemorrhage protocols (MHPs) to prevent and treat coagulopathy. We aimed to determine whether augmenting MHPs with Viscoelastic ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background von Willebrand factor (VWF) multimers are cleaved by A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 (ADAMTS-13) into less active fragments. Thrombospondin 1 (TSP-1) competes ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Scientific studies have demonstrated that it is possible to generate a wide variety of bioenergy from biomass residues and waste, and however its cost is not competitive with petro-fuels and other renewable energy. On-going ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background: Diastasis recti abdominis (DRA) affects a significant number of women in the postpartum period. Objective: To systematically review whether abdominal and pelvic floor muscle (PFM) exercise programs are effective ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Purpose Attention deficit hyperactivity disorder (ADHD) is currently the most prevalent childhood psychiatric diagnosis. This article reports how 10 young adults in Norway positioned themselves before they were diagnosed ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Objective To describe the appearances of bone marrow in the appendicular skeleton on fat-suppressed T2-weighted sequences as assessed by whole-body MRI in healthy and asymptomatic children and adolescents. Material and ...