Browsing Det medisinske fakultet by Title
Now showing items 1-20 of 549
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)In October 2017, the International Olympic Committee hosted an international expert group of physiotherapists and orthopaedic surgeons who specialise in treating and researching paediatric ACL injuries. Representatives ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Zingiber officinale is one of the most frequently used medicinal herbs in Asia. Using rodent seizure models, it was previously shown that Zingiber officinale hydroethanolic extract exerts antiseizure activity, but the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Thrombin activation of C5 connects thrombosis to inflammation. Complement research in whole blood ex vivo necessitates anticoagulation, which potentially interferes with the inflammatory modulation by thrombin. We challenged ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Objectives To develop a risk classifier using urine‐derived extracellular vesicle (EV )‐RNA capable of providing diagnostic information on disease status prior to biopsy, and prognostic information for men on active ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)The catalytic mechanism of the cyclic amidohydrolase isatin hydrolase depends on a catalytically active manganese in the substrate-binding pocket. The Mn2+ ion is bound by a motif also present in other metal dependent ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)Background As farming of Atlantic salmon is growing as an aquaculture enterprise, the need to identify the genomic mechanisms for specific traits is becoming more important in breeding and management of the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Abstract Non-coding variants coordinate transcription factor (TF) binding and chromatin mark enrichment changes over regions spanning >100 kb. These molecularly coordinated regions are named “variable chromatin modules” ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Children's ability to correctly name letters is a key predictor of later reading abilities and skills, but research on letter naming from Scandinavian orthographies is scarce. The aim of this study is to explore how child- ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Abstract During the last decades, there has been an increase in the rate of surgery for degenerative disorders of the cervical spine and in the use of supplementary private health insurance. Still, there is limited knowledge ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background PPKs represent a heterogeneous group of disorders with hyperkeratosis of palmar and/or plantar skin. PPK, hair shaft abnormalities, cardiomyopathy and arrhythmias can be caused by mutations in desmosomal ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background and aim Bariatric surgery is the most effective treatment for obesity but is invasive and associated with serious complications. Endoscopic sleeve gastroplasty (ESG) is a less invasive weight loss procedure ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)We developed a simplified, highly efficient Gateway reaction that recombines target DNA to expression (destination) plasmids in vivo and subsequently conjugates the final vector into a recipient strain, all in a single ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)Background Multigenic diseases are often associated with protein complexes or interactions involved in the same pathway. We wanted to estimate to what extent this is true given a consolidated protein ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)This systematic review summarized findings of 29 studies evaluating visual presentation formats appropriate for communicating measurement uncertainty associated with standardized clinical assessment instruments. Studies ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background Negative symptoms are increasingly recognized as transdiagnostic phenomena, linked to reduced quality of life and functioning, and often caused or worsened by amendable external factors such as depression, social ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2010)Activation of oxidative stress-responses and downregulation of insulin-like signaling (ILS) is seen in Nucleotide Excision Repair (NER) deficient segmental progeroid mice. Evidence suggests that this is a survival response ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)Background The ability to detect neoplasia-specific fusion genes is important not only in cancer research, but also increasingly in clinical settings to ensure that correct diagnosis is made and the optimal ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Context The ability to self‐monitor one's performance in clinical settings is a critical determinant of safe and effective practice. Various studies have shown this form of self‐regulation to be more trustworthy than ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)The annotation of microRNAs depends on the availability of transcriptomics data and expert knowledge. This has led to a gap between the availability of novel genomes and high-quality microRNA complements. Using >16,000 ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background There are several treatment modalities for unresectable neuroendocrine tumors. Traditionally, the aim of these treatments has been to reduce the tumor load; referred to as objective response (OR). Less emphasis ...