Browsing Det medisinske fakultet by Title

Now showing items 446-465 of 596

  • Quantification of ocular surface microcirculation by computer assisted video microscopy and diffuse reflectance spectroscopy 
    Kvernebo, Anne Kari; Miyamoto, Takuma; Sporastøyl, Ane Halse; Wikslund, Liv Kristin; Måsøy, Svein-Erik; Drolsum, Liv; Moe, Morten Carsten; Salerud, Göran; Fukamachi, Kiyotaka; Kvernebo, Knut (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    In piglets we tested the applicability of digital video microscopy and diffuse reflectance spectroscopy for non-invasive assessments of limbal and bulbar conjunctival microcirculation. A priori we postulated that the ...
  • Quantitative chemometric phenotyping of three-dimensional liver organoids by Raman spectral imaging 
    LaLone, Vernon; Aizenshtadt, Aleksandra; Goertz, John; Skottvoll, Frøydis Sved; Mota, Marco Barbero; You, Junji; Zhao, Xiaoyu; Berg, Henriette Engen; Stokowiec, Justyna; Yu, Minzhi; Schwendeman, Anna; Scholz, Hanne; Wilson, Steven Ray Haakon; Krauss, Stefan Johannes Karl; Stevens, Molly M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Confocal Raman spectral imaging (RSI) enables high-content, label-free visualization of a wide range of molecules in biological specimens without sample preparation. However, reliable quantification of the deconvoluted ...
  • Rab7b modulates autophagic flux by interacting with Atg4B 
    Kjos, Ingrid; Distefano, Marita Borg; Sætre, Frank Ove; Repnik, Urska; Holland, Petter; Jones, Arwyn T; Engedal, Nikolai; Simonsen, Anne; Bakke, Oddmund; Progida, Cinzia (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Autophagy (macroautophagy) is a highly conserved eukaryotic degradation pathway in which cytosolic components and organelles are sequestered by specialized autophagic membranes and degraded through the lysosomal system. ...
  • Rapid genome editing by CRISPR-Cas9-POLD3 fusion 
    Reint, Ganna; Li, Zhuokun; Labun, Kornel; Keskitalo, Salla; Soppa, Inkeri; Mamia, Katariina Aino Inkeri; Tolo, Eero; Szymanska, Monika; Meza-Zepeda, Leonardo A.; Lorenz, Susanne; Cieslar-Pobuda, Artur Grzegorz; Hu, Xian; Bodin, Diana L; Staerk, Judith; Valen, Eivind Dale; Schmierer, Bernhard; Varjosalo, Markku; Taipale, Jussi; Haapaniemi, Emma Maria (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Precision CRISPR gene editing relies on the cellular homology-directed DNA repair (HDR) to introduce custom DNA sequences to target sites. The HDR editing efficiency varies between cell types and genomic sites, and the ...
  • Rare Germline Variants Are Associated with Rapid Biochemical Recurrence After Radical Prostate Cancer Treatment: A Pan Prostate Cancer Group Study 
    Burns, Daniel; Anokian, Ezequiel; Saunders, Edward J.; Bristow, Robert G.; Fraser, Michael; Reimand, Jüri; Schlomm, Thorsten; Sauter, Guido; Brors, Benedikt; Korbel, Jan; Weischenfeldt, Joachim; Waszak, Sebastian Martin; Corcoran, Niall M.; Jung, Chol-Hee; Pope, Bernard J.; Hovens, Chris M.; Cancel-Tassin, Géraldine; Cussenot, Olivier; Loda, Massimo; Sander, Chris; Hayes, Vanessa M.; Dalsgaard Sorensen, Karina; Lu, Yong-Jie; Hamdy, Freddie C.; Foster, Christopher S.; Gnanapragasam, Vincent; Butler, Adam; Lynch, Andy G.; Massie, Charlie E.; Woodcock, Dan J.; Cooper, Colin S.; Wedge, David C.; Brewer, Daniel S.; Kote-Jarai, Zsofia; Eeles, Rosalind A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background Germline variants explain more than a third of prostate cancer (PrCa) risk, but very few associations have been identified between heritable factors and clinical progression. Objective To find rare germline ...
  • Rating the quality of teamwork—a comparison of novice and expert ratings using the Team Emergency Assessment Measure (TEAM) in simulated emergencies 
    Freytag, Julia; Stroben, Fabian; Hautz, Wolf E; Schauber, Stefan K; Kämmer, Juliane E (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background Training in teamwork behaviour improves technical resuscitation performance. However, its effect on patient outcome is less clear, partly because teamwork behaviour is difficult to measure. ...
  • Recall and Understanding of Discharge Information in Observation Ward Patients: An Explorative Observational Study 
    Østen, Kjersti; Menichetti, Julia; Nordfalk, Jenny M.; Ofstad, Eirik Hugaas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Effective communication is essential for understanding and recall of hospital discharge information. This study aimed to explore discharge information, patient recall and patient involvement in discharge encounters. We ...
  • Reference-based comparison of adaptive immune receptor repertoires 
    Weber, Cédric R.; Rubio, Teresa; Wang, Longlong; Zhang, Wei; Robert, Philippe Paul Auguste; Akbar, Rahmad; Snapkov, Igor; Wu, Jinghua; Kuijjer, Marieke; Tarazona, Sonia; Conesa, Ana; Sandve, Geir Kjetil Ferkingstad; Liu, Xiao; Reddy, Sai T.; Greiff, Victor (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    B and T cell receptor (immune) repertoires can represent an individual’s immune history. While current repertoire analysis methods aim to discriminate between health and disease states, they are typically based on only a ...
  • Regulated expression of a transgene introduced on an oriP/EBNA-1 PAC shuttle vector into human cells 
    Askautrud, Hanne A; Gjernes, Elisabet; Størvold, Gro L; Lindeberg, Mona M; Thorsen, Jim; Prydz, Hans; Frengen, Eirik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
    Background Sequencing of the human genome has led to most genes being available in BAC or PAC vectors. However, limited functional information has been assigned to most of these genes. Techniques for the ...
  • Regulatory network of PD1 signaling is associated with prognosis in glioblastoma multiforme 
    Lopes-Ramos, Camila; Belova, Tatiana; Brunner, Tess; Ben Guebila, Marouen; Osorio, Daniel; Quackenbush, John; Kuijjer, Marieke (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Glioblastoma is an aggressive cancer of the brain and spine. While analysis of glioblastoma ‘omics data has somewhat improved our understanding of the disease, it has not led to direct improvement in patient survival. ...
  • The relation between face-emotion recognition and social function in adolescents with autism spectrum disorders: A case control study 
    Høyland, Anne Lise; Nærland, Terje; Engstrøm, Morten; Lydersen, Stian; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    An altered processing of emotions may contribute to a reduced ability for social interaction and communication in autism spectrum disorder, ASD. We investigated how face-emotion recognition in ASD is different from typically ...
  • The relationship between pro-inflammatory cytokines and pain, appetite and fatigue in patients with advanced cancer 
    Paulsen, Ørnulf; Laird, Barry J; Aass, Nina Kathrine; Lea, Tor Erling; Fayers, Peter; Kaasa, Stein; Klepstad, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background: Systemic inflammation is associated with reduced quality of life and increased symptoms in patients with advanced cancer. The aims of this study were to examine the relationships between inflammatory biomarkers ...
  • Relevance of Coding Variation in FLG And DOCK8 in Finnish Pediatric Patients with Early-Onset Moderate-To-Severe Atopic Dermatitis 
    Perälä, Miia; Kaustio, Meri; Salava, Alexander; Jakkula, Eveliina; Pelkonen, Anna S.; Saarela, Janna Saija; Remitz, Anita; Mäkelä, Mika J. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Early-onset, persistent atopic dermatitis (AD) is proposed as a distinct subgroup that may have specific genotypic features. FLG gene loss-of-function variants are the best known genetic factors contributing to epidermal ...
  • ReMap 2018: an updated atlas of regulatory regions from an integrative analysis of DNA-binding ChIP-seq experiments 
    Cheneby, J; Gheorghe, Marius; Artufel, M; Mathelier, Anthony; Ballester, B (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    With this latest release of ReMap (http://remap.cisreg.eu), we present a unique collection of regulatory regions in human, as a result of a large-scale integrative analysis of ChIP-seq experiments for hundreds of transcriptional ...
  • Remodeling of secretory lysosomes during education tunes functional potential in NK cells 
    Goodridge, Jodie; Jacobs, Benedikt Marcel; Sætersmoen, Michelle Lu; Clement, Dennis; Hammer, Quirin; Clancy, Trevor; Skarpen, Ellen; Brech, Andreas; Landskron, Johannes; Grimm, Christian; Pfefferle, Aline; Meza, Leonardo Zepeda; Lorenz, Susanne; Wiiger, Merete Thune; Louch, William Edward; Ask, Eivind Heggernes; Liu, Lisa L.; Oei, Vincent Yi Sheng; Kjällquist, Una; Linnarsson, Sten; Patel, Sandip; Tasken, Kjetil; Stenmark, Harald; Malmberg, Karl-Johan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Inhibitory signaling during natural killer (NK) cell education translates into increased responsiveness to activation; however, the intracellular mechanism for functional tuning by inhibitory receptors remains unclear. ...
  • Reply to Ekström and Ottersen: Real-time access to data during outbreaks is a key to avoid a local epidemic becoming a global pandemic 
    Stenseth, Nils Christian; Schlatte, Rudolf; Liu, Xiaoli; Pielke, Roger Jr.; Chen, Ben; Bjørnstad, Ottar Nordal; Kusnezov, Dimitri; Gao, George F.; Fraser, Christophe; Whittington, Jason D; Gong, Peng; Guan, Dabo; Johnsen, Einar Broch (Journal article / Tidsskriftartikkel / PublishedVersion, 2023)
  • Reproduction and the welfare state: Notes on Norwegian biopolitics 
    Shammas, Victor Lund; Sandset, Tony Joakim (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Norway has long been considered to be a bastion of social democracy due to its strong, protective, decommodifying welfare state. However, with the recent rise of neoliberalism and right-wing populist politics across the ...
  • Requirement of PP2A-B56 Par1 for the Stabilization of the CDK Inhibitor Rum1 and Activation of APC/C Ste9 during Pre-Start G1 in S. pombe 
    Stonyte, Vilte; Martîn, Ruth Martîn; Segura-Pena, Dario; Sekulic, Nikolina; Lopez Aviles, Sandra (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Exit from the cell cycle during the establishment of quiescence and upon cell differentiation requires the sustained inactivation of CDK complexes. Fission yeast cells deprived of nitrogen halt cell cycle progression in ...
  • Rethinking Evidence in the Time of Pandemics - Scientific vs Narrative Rationality and Medical Knowledge Practices 
    Engebretsen, Eivind; Baker, Mona (Book / Bok / PublishedVersion; Peer reviewed, 2022)
    his book interrogates the assumption that evidence means the same thing to different constituencies and in different contexts by outlining a more nuanced and socially responsive approach to medical expertise that incorporates ...
  • Retirement age and disability status as pathways to later-life cognitive impairment: Evidence from the Norwegian HUNT Study linked with Norwegian population registers 
    Zotcheva, Ekaterina; Strand, Bjørn Heine; Bowen, Catherine E; Bratsberg, Bernt Magne; Jugessur, Astanand; Engdahl, Bo Lars; Selbæk, Geir; Kohler, Hans-Peter; Harris, Jennifer Ruth; Weiss, Jordan; Grøtting, Maja Weemes; Tom, Sarah E.; Krokstad, Steinar; Stern, Yaakov; Håberg, Asta; Skirbekk, Vegard Fykse (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Background Research shows that retirement age is associated with later‐life cognition but has not sufficiently distinguished between retirement pathways. We examined how retirement age was associated with later‐life ...