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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Cardiovascular disease is a major cause of mortality and morbidity worldwide, and primary prevention efforts are poorly developed in people at high cardiovascular risk. On this background, we ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Second-degree perineal tears are common and can vary widely in the extent of tissue trauma. Therefore, a better understanding of perineal pain based on tissue trauma severity in second-degree tears is ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
The demand for plasma products is growing, necessitating an increase in plasma collection by plasmapheresis. While the 20th edition of the European Guidelines permits plasma donors in Europe to ...
(Chapter / Bokkapittel / PublishedVersion; Peer reviewed, 2024)
This chapter explores how academic textual production may be understood as a practice of responsible agency, through a dialogue between two scholarly texts about microbes. The first emphasizes the discovery of bacteria, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background.
Trabecular bone score (TBS) is a new tool to assess trabecular bone microarchitecture based on standard dual-energy x-ray absorptiometry (DXA) of lumbar spine images. TBS may be important to assess bone ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Production of soluble proteins is essential for structure/function studies; however, this usually requires milligram amounts of protein, which can be difficult to obtain with traditional expression systems. Recently, the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Single-cell technologies enable high-resolution studies of phenotype-defining molecular mechanisms. However, data sparsity and cellular heterogeneity make modeling biological variability across single-cell samples difficult. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract
The vascular endothelium acts as a dynamic interface between blood and tissue. TNF-α, a major regulator of inflammation, induces endothelial cell (EC) transcriptional changes, the overall response dynamics ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Objective:
Dietary assessment tools should be designed for the target population. We developed an FFQ designed to assess diet in South Asian women in Norway. The study objective was to evaluate this FFQ using 24-h dietary ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Low-molecular-weight (LMW) thiols are involved in many processes in all organisms, playing a protective role against reactive species, heavy metals, toxins and antibiotics. Actinobacteria, such as Mycobacterium tuberculosis ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Purpose The PNOC001 phase II single-arm trial sought to estimate progression-free survival (PFS) associated with everolimus therapy for progressive/recurrent pediatric low-grade glioma (pLGG) on the basis of phosphatidylinositol ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background: Biodegradable poly(alkyl cyanoacrylate) (PACA) nanoparticles (NPs) are receiving increasing attention in anti-cancer nanomedicine development not only for targeted cancer chemotherapy, but also for modulation ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Abstract Background Hereditary palmoplantar keratodermas (hPPKs) comprise a heterogeneous group of skin disorders characterized by persistent palmoplantar hyperkeratosis. Loss‐of‐function variants in a serine peptidase ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
When making complex decisions, such as a medical diagnosis, decision makers typically gather, analyze, and synthesize (integrate) information. In a previous study, we showed that delegating such complex decisions to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA) which is the precursor of the photosensitizer protoporphyrin IX (PpIX) is an available treatment for several diseases. ALA-PDT induces the apoptosis and necrosis ...
(Journal article / Tidsskriftartikkel / PublishedVersion, 2023)
Modeling networks for single samples can facilitate discoveries in biology that go beyond those found when analyzing an “aggregate” network, i.e., one that merges information across all the samples in an omics data set. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Patients with H3K27M-mutant diffuse midline glioma (DMG) have no proven effective therapies. ONC201 has recently demonstrated efficacy in these patients, but the mechanism behind this finding remains unknown. We assessed ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
The bacterial magnesium transporter A (MgtA) is a specialized P-type ATPase important for Mg2+ import into the cytoplasm; disrupted magnesium homeostasis is linked to intrinsic ribosome instability and antibacterial ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Colorectal and ovarian cancers frequently develop peritoneal metastases with few treatment options. Intraperitoneal chemotherapy has shown promising therapeutic effects, but is limited by rapid drug clearance and systemic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background Increasing syncytiotrophoblast stress in term and postdate placentas is reflected by increasing antiangiogenic dysregulation in the maternal circulation, with low “proangiogenic” placental growth factor ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Nuclear factor κ light-chain enhancer of activated B cells (NF-κB) family of evolutionarily conserved transcription factors are involved in key cellular signaling pathways. Previously, hypogammaglobulinemia and common ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Obesity is associated with an increased risk of developing breast cancer (BC) and worse prognosis in BC patients, yet its impact on BC biology remains understudied in humans. This study investigates how the biology ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background and aims
We previously demonstrated that people with primary sclerosing cholangitis (PSC) had reduced gut microbial capacity to produce active vitamin B6 (pyridoxal 5’-phosphate [PLP]), which corresponded to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background: The relationship between the skin barrier- and lung function in infancy is largely unexplored. We aimed to explore if reduced skin barrier function by high transepidermal water loss (TEWL), or manifestations ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract
Purpose
Triglycerides (TG) and their major transport lipoprotein in the circulation (VLDL) appear to be related to inflammation. Patients with common variable immunodeficiency (CVID) have ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract
Background
Diffuse midline gliomas (DMG) are highly invasive brain tumors with rare survival beyond two years past diagnosis and limited understanding of the mechanism behind tumor ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Lifestyle disorders like obesity, type 2 diabetes (T2D), and cardiovascular diseases can be prevented and treated by regular physical activity. During exercise, skeletal muscles release signaling factors that communicate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Objectives
Immune responses following SARS-CoV-2 vaccination in patients with inflammatory bowel disease (IBD) are not well characterized. The aims of this study were to explore the serological response associated with ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Physical activity is associated with beneficial adaptations in human and rodent metabolism. We studied over 50 complex traits before and after exercise intervention in middle-aged men and a panel of 100 diverse strains of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background and aim
Bariatric surgery is the most effective treatment for obesity but is invasive and associated with serious complications. Endoscopic sleeve gastroplasty (ESG) is a less invasive weight loss procedure ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Terror exposure increases the risk of somatic and psychological health problems in survivors. Yet, knowledge of how such exposure affects survivors’ ability to stay in school is lacking. This study examined whether exposure ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Purpose
The aim of the present study was to explore the next of kin’s experiences with the transition for people with dementia from a farm-based daycare (FDC) to another service in the municipality.
Methods
The study ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background Negative symptoms are increasingly recognized as transdiagnostic phenomena, linked to reduced quality of life and functioning, and often caused or worsened by amendable external factors such as depression, social ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Generalised anxiety disorder (GAD) is a frequent and severe disorder among older adults. For older adults with GAD the effect of the recommended treatment, cognitive behaviour therapy (CBT), is ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
von Willebrand factor (VWF) multimers are cleaved by A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 (ADAMTS-13) into less active fragments. Thrombospondin 1 (TSP-1) competes ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Objective To evaluate epidemiology and outcomes among very preterm infants (<32 weeks’ gestation) with culture-positive and culture-negative late-onset sepsis (LOS). Design Cohort study using a nationwide, population-based ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background Neuroinflammation is involved in the pathophysiology of Alzheimer's disease (AD), including immune-linked genetic variants and molecular pathways, microglia and astrocytes. Multiple Sclerosis (MS) is a chronic, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Brain age refers to age predicted by brain features. Brain age has previously been associated with various health and disease outcomes and suggested as a potential biomarker of general health. Few previous studies have ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Human epidermal growth factor receptor 2-positive (HER2+) breast cancer is an aggressive subtype of this disease. Targeted treatment has improved outcome, but there is still a need for new therapeutic strategies as some ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Cellular homeostasis is governed by removal of damaged organelles and protein aggregates by selective autophagy mediated by cargo adaptors such as p62/SQSTM1. Autophagosomes can assemble in specialized cup-shaped ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract
Aims
Heart failure is a condition with high mortality rates, and there is a lack of therapies that directly target maladaptive changes in the extracellular matrix (ECM), such as ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract
Objectives
MTX, LEF and SSZ are conventional synthetic DMARDs (csDMARDs) with a well-established role in the treatment of RA. We aimed to estimate and compare the relative risks ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Objectives Unsafe medical care causes morbidity and mortality among the hospital patients. In a postanaesthesia care unit (PACU), increasing patient safety is a joint effort between different professions. The Green Cross ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Lipid metabolism is essential in maintaining energy homeostasis in multicellular organisms. In vertebrates, the peroxisome proliferator-activated receptors (PPARs, NR1C) regulate the expression of many genes involved in ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Objective: To evaluate adherence to 3 central operational recommendations for acute rehabilitation in the Norwegian trauma plan.Methods: A prospective multi-centre study of 538 adults with moderate and severe trauma with ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Millions of single nucleotide variants (SNVs) exist in the human genome; however, it remains challenging to identify functional SNVs associated with diseases. We propose a non-encoding SNVs analysis tool bpb3, BayesPI-BAR ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Introduction The use of proton therapy increases globally despite a lack of randomised controlled trials demonstrating its efficacy and safety. Proton therapy enables sparing of non-neoplastic tissue from radiation. This ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background The iron-regulatory hormone hepcidin is a promising biomarker to differentiate anaemia of inflammation from iron deficiency. Plasma hepcidin concentrations increase substantially during inflammation, and the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Cell fate can be reprogrammed by ectopic expression of lineage-specific transcription factors (TFs). However, the exact cell state transitions during transdifferentiation are still poorly understood. Here, we have generated ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Ensuring a more equitable distribution of vaccines worldwide is an effective strategy to control global pandemics and support economic recovery. We analyze the socioeconomic effects - defined as health gains, lockdown-easing ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Introduction
The incidence of invasive meningococcal disease (IMD) among Norwegian 16–19-year-olds was 1–7/100,000 in the decade before the COVID-19 pandemic, with serogroup Y (MenY) dominance. In contrast to many other ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Background Research shows that retirement age is associated with later‐life cognition but has not sufficiently distinguished between retirement pathways. We examined how retirement age was associated with later‐life ...
Non-Coding RNA in Salivary Extracellular Vesicles: A New Frontier in Sjögren's Syndrome Diagnostics?
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Sjögren’s syndrome is an autoimmune rheumatic disease characterized by inflammation of the salivary and lacrimal glands, often manifesting as dry mouth and dry eyes. To simplify diagnostics of primary Sjögren’s syndrome ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
MYB plays a key role in gene regulation throughout the hematopoietic hierarchy and is critical for the maintenance of normal hematopoietic stem cells (HSC). Acquired genetic dysregulation of MYB is involved in the etiology ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Cells use noncanonical autophagy, also called conjugation of ATG8 to single membranes (CASM), to label damaged intracellular compartments with ubiquitin‐like ATG8 family proteins in order to signal danger caused ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Objective
To investigate whether high-sensitivity cardiac troponin T (hsTnT) correlates to markers of disease activity in inflammatory arthritis (IA), and whether antirheumatic treatment influences hsTnT levels.
Methods
We ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract The present study investigated therapist adherence, therapist competence, and patient-therapist alliance as predictors of long-term outcomes of cognitive behavioral therapy (CBT) for anxiety disorders in youth. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Objectives
Late-life depression (LLD) is a common and debilitating disorder. Previously, resting-state studies have revealed abnormal functional connectivity (FC) of brain networks in LLD. Since LLD is associated with ...
The efferent connections of theorbitofrontal, posterior parietal,and insular cortex of the rat brain
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract The orbitofrontal, posterior parietal, and insular cortices are sites of higher-order cognitive processing implicated in a wide range of behaviours, including working memory, attention guiding, decision making, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Importance The prevalence and baseline risk factors of post–COVID-19 condition (PCC) remain unresolved among the large number of young people who experienced mild COVID-19.
Objectives To determine the point prevalence ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Continually emerging SARS-CoV-2 variants of concern that can evade immune defenses are driving recurrent epidemic waves of COVID-19 globally. However, the impact of measures to contain the virus and their effect on lineage ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Fetal growth restricted (FGR) neonates have increased risk of circulatory compromise due to failure of normal transition of circulation after birth.
Aim
Echocardiographic assessment of heart function in ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract
Purpose
To provide an overview of the The Norwegian Degenerative spondylolisthesis and spinal stenosis (NORDSTEN)-study and the organizational structure, and to evaluate the study population. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Brain atlases are important reference resources for accurate anatomical description of neuroscience data. Open access, three-dimensional atlases serve as spatial frameworks for integrating experimental data and defining ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
Persistent dyspnea, functional limitations, and reduced quality of life (QoL) are common following pulmonary embolism (PE). Rehabilitation is a potential treatment option, but the scientific evidence is ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Here, we combine international air travel passenger data with a standard epidemiological model of the initial 3 mo of the COVID-19 pandemic (January through March 2020; toward the end of which the entire world locked down). ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Long-term antibiotics are prescribed for a variety of medical conditions, recently including low back pain with Modic changes. The molecular impact of such treatment is unknown. We conducted longitudinal transcriptome and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
BAKGRUNN
Nasjonalt pasientforløp (tidligere kalt pakkeforløp) for oppfølging etter rusmiddeloverdose er en viktig del av nasjonal overdosestrategi og trådte i kraft 1. januar 2022. Fire år forut for dette ble det innledet ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
This systematic review summarized findings of 29 studies evaluating visual presentation formats appropriate for communicating measurement uncertainty associated with standardized clinical assessment instruments. Studies ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background: The incidence of pediatric and adolescent anterior cruciate ligament reconstruction (ACLR) is increasing in several countries. It is uncertain whether this trend applies to countries that traditionally prefer ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Mutations in POLG , the gene encoding the catalytic subunit of the mitochondrial DNA (mtDNA) polymerase gamma (Pol‐γ), lead to diseases driven by defective mtDNA maintenance. Despite being the most prevalent cause ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background/Aim: CIC-sarcomas are characterized by rearrangements of the capicua transcriptional repressor (CIC) gene on chromosome subband 19q13.2, generating chimeras in which CIC is the 5′-end partner. Most reported ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Lytic polysaccharide monooxygenases (LPMOs) are surface-active redox enzymes that catalyze the degradation of recalcitrant polysaccharides, making them important tools for energy production from renewable sources. In ...
(Journal article / Tidsskriftartikkel / PublishedVersion, 2023)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Background and purpose Little is known about the comparative effects of migraine preventive drugs. We aimed to estimate treatment retention and effectiveness of migraine preventive drugs in a nationwide registry‐based ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
BACKGROUND CONTEXT
Patients with spinal stenosis and degenerative spondylolisthesis are treated surgically with decompression alone or decompression with fusion. However, there is debate regarding which subgroups of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background: Low bone mineral density (BMD) increases the risk of bone stress injuries (BSI) and is one of several clinical concerns in Para athlete sports medicine. However, whether bone microarchitecture is altered in ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background: Human papillomavirus (HPV) infection is a risk factor for the development of penile squamous cell carcinoma (PSCC). It remains inconclusive whether HPV-related PSCC has a different prognosis from non-HPV-related ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Aurora B, together with IN-box, the C-terminal part of INCENP, forms an enzymatic complex that ensures faithful cell division. The [Aurora B/IN-box] complex is activated by autophosphorylation in the Aurora B activation ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2023)
The rates of chemical reactions involved in cell-to-cell communication can serve as a powerful tool for advanced theranostics and in establishing a molecular communication link between bio-transceivers. Reaction rates are ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Age-related gut bacterial changes during infancy have been widely studied, but it remains still unknown how these changes are associated with immune cell composition. This study's aim was to explore if the temporal development ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background/Aim: Lipomas are benign tumors composed of mature fat cells. They are common soft tissue tumors that often carry chromosome aberrations involving 12q14 resulting in rearrangements, deregulation, and generation ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract
MiniPromoters, or compact promoters, are short DNA sequences that can drive expression in specific cells and tissues. While broadly useful, they are of high relevance to gene therapy due to their role ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Introduction Eosinophil‐derived neurotoxin (EDN) is related to childhood asthma, while normal values are lacking. We aimed to document serum EDN levels at 1 and 3 years in general and in non‐atopic children, and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
CD4+ T cells specific for cereal gluten proteins are key players in celiac disease (CeD) pathogenesis. While several CeD-relevant gluten T cell epitopes have been identified, epitopes recognized by a substantial proportion ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Short sleep is held to cause poorer brain health, but is short sleep associated with higher rates of brain structural decline? Analysing 8,153 longitudinal MRIs from 3,893 healthy adults, we found no evidence for ...
Anomalous Diffusion of Extracellular Vesicles in an Extracellular Matrix for Molecular Communication
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2023)
Anomalous diffusion of extracellular vesicles (EVs) occurs because of the natural stiffness and stress relaxation of the extracellular matrix (ECM). This phenomenon has not been considered so far in attempts of computational ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background. Task shifting is a systematic delegation of tasks in order to make more efficient use of the available human resources for health. Training programs and the quality of these are sparsely studied and specially ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
The etiology of autism spectrum disorder (ASD) is multifactorial, involving genetic and environmental contributors such as endocrine-disrupting chemicals (EDCs).
Objective
To evaluate the association ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract
C1 inhibitor (C1Inh) is a serine protease inhibitor involved in the kallikrein-kinin system, the complement system, the coagulation system, and the fibrinolytic system. In addition to the plasma leakage ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Objectives Patients missing their scheduled appointments in specialist healthcare without giving notice can undermine efficient care delivery. To reduce patient non-attendance and possibly compensate healthcare providers, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Objective: Developmental dysplasia of the hip (DDH) is a congenital condition affecting 2-3% of all infants. DDH increases the risk of osteoarthritis, is the cause of 30% of all total hip arthroplasties (THAs) in adults ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Introduction
Human papillomavirus (HPV) infection is common in women of reproductive age. Infection and inflammation are leading causes for preterm delivery (PTD), but the role of HPV infection in PTD and prelabor rupture ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background: A correct approach to recurrent urinary tract infections (rUTIs) is an important pillar of antimicrobial stewardship. We aim to define an Artificial Neural Network (ANN) for predicting the clinical efficacy of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract Introduction Increased BMI has been identified as a risk factor for most pregnancy complications, but the underlying metabolic factors mediating the detrimental effects of BMI are largely unknown. We aimed to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Inference and analysis of gene regulatory networks (GRNs) require software that integrates multi-omic data from various sources. The Network Zoo (netZoo; netzoo.github.io) is a collection of open-source methods to infer ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Quantifying how the cellular composition of brain regions vary across development, aging, sex, and disease, is crucial in experimental neuroscience, and the accuracy of different counting methods is continuously debated. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Abstract
Characterizing inter-tumor heterogeneity is crucial for selecting suitable cancer therapy, as the presence of diverse molecular subgroups of patients can be associated with disease outcome or response ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
There is a growing acceptance that ADHD is a multi-dimensional disorder in which not all symptoms are associated with deficits or functional impairments. This article contributes to research on the positive aspects of the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Purpose
Attention deficit hyperactivity disorder (ADHD) is currently the most prevalent childhood psychiatric diagnosis. This article reports how 10 young adults in Norway positioned themselves before they were diagnosed ...