Browsing Det medisinske fakultet by Title

Now showing items 232-251 of 599

  • Health Preparedness and Narrative Rationality: A Call for Narrative Preparedness 
    Engebretsen, Eivind; Baker, Mona (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    This conceptual paper argues the need for narrative preparedness, understood as the ability to engage and empathize with peoples’ stories and the values they encode, assess them based on the universe in which people live, ...
  • Health-related quality of life in young Norwegian survivors of out-of-hospital cardiac arrest related to pre-arrest exercise habits 
    Isern, Cecilie Benedicte; Nilsson, Birgitta Blakstad; Garratt, Andrew; Kramer-Johansen, Jo; Tjelmeland Myrhaugen, Ingvild Beathe; Berge, Hilde Moseby (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Aim To compare health-related quality of life (HRQoL) in young survivors of out-of-hospital cardiac arrest (OHCA) in Norway with an age and sex-matched reference population and to assess the associations between exercise ...
  • Heart function by M-mode and tissue Doppler in the early neonatal period in neonates with fetal growth restriction 
    Nestaas, Eirik; BJARKØ, LISA; Kiserud, Torvid; Haugen, Guttorm Nils; Fugelseth, Drude (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Fetal growth restricted (FGR) neonates have increased risk of circulatory compromise due to failure of normal transition of circulation after birth. Aim Echocardiographic assessment of heart function in ...
  • Helicobacter pylori resistance to antibiotics before and after treatment: Incidence of eradication failure 
    Nestegard, Oddmund; Moayeri, Behrouz; Halvorsen, Fred-Arne; Tønnesen, Tor; Sørbye, Sveinung; Paulssen, Eyvind Jakob; Johnsen, Kay-Martin; Goll, Rasmus; Florholmen, Jon; Melby, Kjetil K. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background Increasing prevalence of antibiotic resistance especially to clarithromycin and metronidazole has been observed in Helicobacter pylori (H. pylori). Aim To characterize the antimicrobial resistance pattern ...
  • Hematopoietic Cell Transplantation Cures Adenosine Deaminase 2 Deficiency: Report on 30 Patients 
    Hashem, Hasan; Bucciol, Giorgia; Ozen, Seza; Unal, Sule; Ok Bozkaya, Ikbal; Akarsu, Nurten; Taskinen, Mervi; Koskenvuo, Minna; Saarela, Janna Saija; Dimitrova, Dimana; Hickstein, Dennis D; Hsu, Amy P.; Holland, Steven M.; Krance, Robert A.; Sasa, Ghadir; Kumar, Ashish R; Müller, Ingo; de Sousa, Monica Abreu; Delafontaine, Selket; Moens, Leen; Babor, Florian; Barzaghi, Federica; Cicalese, Maria Pia; Bredius, Robbert; van Montfrans, Joris; Baretta, Valentina; Cesaro, Simone; Stepensky, Polina; Benedicte, Nevn; Moshous, Despina; Le Guenno, Guillaume; Boutboul, David; Dalal, Jignesh; Brooks, Joel P; Dokmeci, Elif; Dara, Jasmeen; Lucas, Carrie L; Hambleton, Sophie; Wilson, Keith; Jolles, Stephen; Koc, Yener; Güngör, Tayfun; Schnider, Caroline; Candotti, Fabio; Steinmann, Sandra; Schulz, Ansgar; Chambers, Chip; Hershfield, Michael S; Ombrello, Amanda; Kanakry, Jennifer A; Meyts, Isabelle (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Abstract Purpose Deficiency of adenosine deaminase 2 (DADA2) is an inherited inborn error of immunity, characterized by autoinflammation (recurrent fever), vasculopathy (livedo racemosa, polyarteritis ...
  • Hepatitis B in Africa Collaborative Network: cohort profile and analysis of baseline data 
    Riches, Nicholas; Vinikoor, Michael; Guingane, Alice; Johannessen, Asgeir; Lemoine, Maud; Matthews, Philippa; Okeke, Edith; Shimakawa, Yusuke; Sombie, Roger; Stockdale, Alexander; Wandeler, Gilles; Andersson, Monique; Davwar, Pantong; Desalegn, Hailemichael; Duguru, Mary; Fall, Fatou; Maponga, Tongai; Nyam Paul, David; Seydi, Moussa; Sinkala, Edford; Taljaard, Jantjie; Sonderup, Mark; Spearman, C. Wendy (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Approximately 80 million people live with chronic hepatitis B virus (HBV) infection in the WHO Africa Region. The natural history of HBV infection in this population is poorly characterised, and may differ ...
  • Hepcidin analysis in pneumonia: Comparison of immunoassay and LC-MS/MS 
    Oppen, Kjersti; Brede, Cato; Skadberg, Øyvind; Steinsvik, Trude; Holter, Jan Cato; Michelsen, Annika Elisabet; Heggelund, Lars (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background The iron-regulatory hormone hepcidin is a promising biomarker to differentiate anaemia of inflammation from iron deficiency. Plasma hepcidin concentrations increase substantially during inflammation, and the ...
  • HER2 expression patterns in paired primary and metastatic endometrial cancer lesions 
    Halle, Mari Kyllesø; Tangen, Ingvild Løberg; Berg, Hege Fredriksen; Hoivik, Erling A; Mauland, Karen Klepsland; Kusonmano, Kanthida; Berg, Anna; Rodriguez, Antoni Hurtado; Kalland, Karl; Øyan, Anne Margrete; Stefansson, Ingunn; Vintermyr, Olav Karsten; Werner, Henrica Maria Johanna; Haldorsen, Ingfrid S.; Trovik, Jone; Salvesen, Helga; Krakstad, Camilla (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background: Despite successful implementation of drugs targeting the human epidermal growth factor receptor 2 (HER2) receptor in breast and gastric cancers, the potential of HER2 as a therapeutic target in other cancers ...
  • Herpes simplex virus 2 encephalitis in a patient heterozygous for a TLR3 mutation 
    Hautala, Timo; Chen, Jie; Tervonen, Laura; Partanen, Terhi; Winqvist, Satu; Lehtonen, Johanna; Saarela, Janna; Kraatari, Minna; Kuismin, Outi; Vuorinen, Tytti; Glumoff, Virpi; Åström, Pirjo; Huuskonen, Usko; Lorenzo, Lazaro; Casanova, Jean-Laurent; Zhang, Shen-Ying; Seppänen, Mikko R.J. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
  • Heterogeneity in the gene regulatory landscape of leiomyosarcoma 
    Belova, Tatiana; Biondi, Nicola; Hsieh, Ping-Han; Lutsik, Pavlo; Chudasama, Priya; Kuijjer, Marieke (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Abstract Characterizing inter-tumor heterogeneity is crucial for selecting suitable cancer therapy, as the presence of diverse molecular subgroups of patients can be associated with disease outcome or response ...
  • Heterozygous BRCA1 and BRCA2 and Mismatch Repair Gene Pathogenic Variants in Children and Adolescents With Cancer 
    Kratz, Christian P.; Smirnov, Dmitrii; Autry, Robert; Jäger, Natalie; Waszak, Sebastian Martin; Großhennig, Anika; Berutti, Riccardo; Wendorff, Mareike; Hainaut, Pierre; Pfister, Stefan M.; Prokisch, Holger; Ripperger, Tim; Malkin, David (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract Background Genetic predisposition is has been identified as a cause of cancer, yet little is known about the role of adult cancer predisposition syndromes in childhood cancer. We ...
  • Heterozygous TLR3 Mutation in Patients with Hantavirus Encephalitis 
    Partanen, Terhi; Chen, Jie; Lehtonen, Johanna; Kuismin, Outi; Rusanen, Harri; Vapalahti, Olli; Vaheri, Antti; Anttila, Veli-Jukka; Bode, Michaela; Hautala, Nina; Vuorinen, Tytti; Glumoff, Virpi; Kraatari, Minna; Åström, Pirjo; Saarela, Janna; Kauma, Heikki; Lorenzo, Lazaro; Casanova, Jean-Laurent; Zhang, Shen-Ying; Seppänen, Mikko; Hautala, Timo (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Puumala hantavirus (PUUV) hemorrhagic fever with renal syndrome (HFRS) is common in Northern Europe; this infection is usually self-limited and severe complications are uncommon. PUUV and other hantaviruses, however, can ...
  • High intraocular pressure in eyes with late in-the-bag intraocular lens dislocation 
    Kristianslund, Olav; Dalby, Marius; Drolsum, Liv (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    The frequency of late in-the-bag intraocular lens (IOL) dislocation has increased over the past decades. Important predisposing factors are pseudoexfoliation syndrome (PXF), myopia, previous vitreoretinal surgery, and ...
  • High OGT activity is essential for MYC-driven proliferation of prostate cancer cells 
    Itkonen, Harri; Urbanucci, Alfonso; Sara ES, Martin; Khan, Aziz; Mathelier, Anthony; Thiede, Bernd; Walker, Suzanne; Mills, Ian Geoffrey (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    O-GlcNAc transferase (OGT) is overexpressed in aggressive prostate cancer. OGT modifies intra-cellular proteins via single sugar conjugation (O-GlcNAcylation) to alter their activity. We recently discovered the first ...
  • High prevalence of low bone mineral density but normal trabecular bone score in Norwegian elite Para athletes 
    Koivisto-Mørk, Anu; Steffen, Kathrin; Finnes, Trine Elisabeth; Pretorius, Mikkel; Berge, Hilde Moseby (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background: Low bone mineral density (BMD) increases the risk of bone stress injuries (BSI) and is one of several clinical concerns in Para athlete sports medicine. However, whether bone microarchitecture is altered in ...
  • High Throughput Chemical Screening Reveals Multiple Regulatory Proteins on FOXA1 in Breast Cancer Cell Lines 
    Wang, Shixiong; Singh, Sachin Kumar; Katika, MR; Lopez-Aviles, Sandra; Rodriguez, Antoni Hurtado (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Forkhead box A1 (FOXA1) belongs to the forkhead class transcription factor family, playing pioneering function for hormone receptors in breast and prostate cancers, and mediating activation of linage specific enhancers. ...
  • High-Intensity Interval Training in Patients with Heart Failure with Reduced Ejection Fraction 
    Ellingsen, Øyvind; Halle, Martin; Conraads, Viviane; Støylen, Asbjørn; Dalen, Håvard; Delagardelle, Charles; Larsen, Alf Inge; Hole, Torstein; Mezzani, Alessandro; Van Craenenbroeck, Emeline M.; Videm, Vibeke; Beckers, Paul; Christle, Jeffrey W.; Winzer, Ephraim; Mangner, Norman; Woitek, Felix; Höllriegel, Robert; Pressler, Axel; Monk-Hansen, Tea; Snoer, Martin; Feiereisen, Patrick; Valborgland, Torstein; Kjekshus, John; Hambrecht, Rainer; Gielen, Stephan; Karlsen, Trine; Prescott, Eva; Linke, Axel (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Background: Small studies have suggested that high-intensity interval training (HIIT) is superior to moderate continuous training (MCT) in reversing cardiac remodeling and increasing aerobic capacity in patients with heart ...
  • High-sensitivity cardiac troponin T is associated with disease activity in patients with inflammatory arthritis 
    Nguyen, Thao; Fagerland, Morten; Hollan, Ivana; Whist, Jon Elling; Feinberg, Mark W.; Agewall, Stefan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Objective To investigate whether high-sensitivity cardiac troponin T (hsTnT) correlates to markers of disease activity in inflammatory arthritis (IA), and whether antirheumatic treatment influences hsTnT levels. Methods We ...
  • High-throughput screen in vitro identifies dasatinib as a candidate for combinatorial treatment with HER2-targeting drugs in breast cancer 
    Normann, Lisa Svartdal; Haugen, Mads; Hongisto, Vesa; Aure, Miriam Ragle; Leivonen, Suvi-Katri; Kristensen, Vessela N.; Tahiri, Andliena; Engebråten, Olav; Sahlberg, Guro Kristine Kleivi; Mælandsmo, Gunhild Mari (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Human epidermal growth factor receptor 2-positive (HER2+) breast cancer is an aggressive subtype of this disease. Targeted treatment has improved outcome, but there is still a need for new therapeutic strategies as some ...
  • Hip Structure Analyses in Acromegaly: Decrease of Cortical Bone Thickness After Treatment: A Longitudinal Cohort Study 
    Godang, Kristin; Lekva, Tove; Normann, Kjersti Ringvoll; Olarescu, Nicoleta Cristina; Øystese, Kristin Astrid; Kolnes, Anders Jensen; Ueland, Thor; Bollerslev, Jens; Heck, Ansgar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Long‐standing growth hormone (GH) excess causes the skeletal clinical signs of acromegaly with typical changes in bone geometry, including increased cortical bone thickness (CBT). However, a high prevalence and incidence ...