Browsing Det medisinske fakultet by Title

Now showing items 56-75 of 598

  • Basic self-disturbances are associated with Sense of Coherence in patients with psychotic disorders 
    Svendsen, Ingrid Hartveit; Øie, Merete Glenne; Møller, Paul; Nelson, Barnaby; Melle, Ingrid; Haug, Elisabeth (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background The Sense of Coherence (SOC) theory gives a possible explanation of how people can experience subjective good health despite severe illness. Basic self-disturbances (BSDs) are subtle non-psychotic disturbances ...
  • Behavioral effects of sub-anesthetic ketamine in a go/no-go task 
    Nilsen, Andre Sevenius; Juel, Bjørn Erik; Farnes, Nadine; Romundstad, Luis Georg; Storm, Johan Frederik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Background and aims While psychedelic agents are known to have powerful, but largely unexplained, effects on contents of consciousness, there is an increasing interest in the potential clinical usefulness of such drugs ...
  • Being sheltered from a demanding everyday life: experiences of the next of kin to people with dementia attending farm-based daycare 
    Taranrød, Liv Bjerknes; Pedersen, Ingeborg; Kirkevold, Øyvind; Eriksen, Siren (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Purpose Farm-based daycare (FDC) is a type of daycare service for people with dementia. The aim of the present study was to explore the next of kin’s experiences with FDC and how the service may affect their daily life. ...
  • BiasAway: command-line and web server to generate nucleotide composition-matched DNA background sequences. 
    Khan, Aziz; Riudavets Puig, Rafael; Boddie, Paul; Mathelier, Anthony (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract Motivation Accurate motif enrichment analyses depend on the choice of background DNA sequences used, which should ideally match the sequence composition of the foreground sequences. ...
  • Bio-psycho-social factors’ associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants 
    Korbmacher, Max; Gurholt, Tiril Pedersen; de Lange, Ann Marie; Van der meer, Dennis; Beck, Dani; Eikefjord, Eli Nina; Lundervold, Arvid; Andreassen, Ole; Maximov, Ivan (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Brain age refers to age predicted by brain features. Brain age has previously been associated with various health and disease outcomes and suggested as a potential biomarker of general health. Few previous studies have ...
  • Biodistribution of Poly(alkyl cyanoacrylate) Nanoparticles in Mice and Effect on Tumor Infiltration of Macrophages into a Patient-Derived Breast Cancer Xenograft 
    Pandya, Abhilash D.; Iversen, Tore Geir; Moestue, Siver Andreas; Grinde, Maria Tunset; Mørch, Ýrr Asbjørg; Snipstad, Sofie; Åslund, Andreas; Øy, Geir Frode; Kildal, Wanja; Engebråten, Olav; Sandvig, Kirsten; Skotland, Tore; Mælandsmo, Gunhild Mari (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    We have investigated the biodistribution and tumor macrophage infiltration after intravenous injection of the poly(alkyl cyanoacrylate) nanoparticles (NPs): PEBCA (poly(2-ethyl-butyl cyanoacrylate), PBCA (poly(n-butyl ...
  • Biological lipid nanotubes and their potential role in evolution 
    Gözen, Irep; Dommersnes, Paul Gunnar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    The membrane of cells and organelles are highly deformable fluid interfaces, and can take on a multitude of shapes. One distinctive and particularly interesting property of biological membranes is their ability to from ...
  • Blood pressure in dementia, mild cognitive impairment, and subjective cognitive decline related to time of death 
    Hestad, Knut; Engedal, Knut; Selbæk, Geir; Strand, Bjørn Heine (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Objective: It is unknown whether systolic blood pressure (SBP) drop is part of the normal aging process or due to the onset of dementia for some people. SBP drop is referring to the decrease in blood pressure often seen ...
  • BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5 
    Bollum, Lise Kristin; Huse, Kanutte; Oksvold, Morten Pedersen; Bai, Baoyan; Hilden, Vera Irene; Forfang, Lise; Yoon, So; Wälchli, Sébastien; Smeland, Erlend B; Myklebust, June (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Selection and maturation of B cells into plasma cells producing high-affinity antibodies occur in germinal centers (GC). GCs form transiently in secondary lymphoid organs upon antigen challenge, and the GC reaction is a ...
  • Brain amyloid and vascular risk are related to distinct white matter hyperintensity patterns 
    Pålhaugen, Lene; Sudre, Carole H; Teceläo, Sandra Raquel Ramos; Nakling, Arne; Almdahl, Ina Selseth; Kalheim, Lisa Flem; Cardoso, M Jorge; Johnsen, Stein Harald; Rongve, Arvid; Aarsland, Dag; Bjørnerud, Atle; Selnes, Per; Fladby, Tormod (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    White matter hyperintensities (WMHs) are associated with vascular risk and Alzheimer’s disease. In this study, we examined relations between WMH load and distribution, amyloid pathology and vascular risk in 339 controls ...
  • Brain-wide glymphatic enhancement and clearance in humans assessed with MRI 
    Ringstad, Geir; Valnes, Lars Magnus; Dale, Anders; Pripp, Are Hugo; Vatnehol, Svein Are Sirirud; Emblem, Kyrre Eeg; Mardal, Kent-Andre; Eide, Per Kristian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    To what extent does the subarachnoid cerebrospinal fluid (CSF) compartment communicate directly with the extravascular compartment of human brain tissue? Interconnection between the subarachnoid CSF compartment and brain ...
  • Bromodomain-containing proteins in prostate cancer 
    Urbanucci, Alfonso; Mills, Ian Geoffrey (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    Several oncogenic factors have been involved in prostate cancer progression. However, therapeutic approaches still focus on suppression of androgen receptor (AR) signaling. In fact, whereas the full-length AR incorporates ...
  • Brown and brite adipocytes: Same function, but different origin and response 
    Chu, Dinh Toi (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Inducing brown adipocytes in white adipose tissues is a promising target to combat obesity and its related disorders in human beings. This goal has been especially encouraged by new important discoveries of human brown ...
  • C57BL/6J mice as a polygenic developmental model of diet-induced obesity 
    Chu, Dinh Toi; Malinowska, Elzbieta; Jura, Magdalena; Kozak, Leslie P (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Susceptibility to obesity changes during the course of life. We utilized theC57BL/6J (B6) and 129S mouse as a genetic model for variation in diet-induced obesity to define the adiposity phenotypes from birth to maturity ...
  • Calibration of sodium iodide detectors and reentrant ionization chambers for 212Pb activity in different geometries by HPGe activity determined samples 
    Napoli, Elisa; Stenberg, Vilde Yuli; Juzeniene, Asta; Hjellum, Gro E.; Bruland, Øyvind; Larsen, Roy H. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Lead-212 is a promising radionuclide for cancer therapy, but no primary 212Pb activity standardization has been published. A need therefore exists for accurate estimation of injected doses of 212Pb activity in equilibrium ...
  • Cancer risk and tumour spectrum in 172 patients with a germline SUFU pathogenic variation: A collaborative study of the SIOPE Host Genome Working Group 
    Guerrini-Rousseau, Lea; Masliah-Planchon, Julien; Waszak, Sebastian Martin; Alhopuro, Pia; Benusiglio, Patrick R; Bourdeaut, Franck; Brecht, Ines B; Del Baldo, Giada; Dhanda, Sandeep Kumar; Garre, Maria Luisa; Gidding, Corrie E M; Hirsch, Steffen; Hoarau, Pauline; Jorgensen, Mette; Kratz, Christian; Lafay-Cousin, Lucie; Mastronuzzi, Angela; Pastorino, Lorenza; Pfister, Stefan M; Schroeder, Christopher; Smith, Miriam Jane; Vahteristo, Pia; Vibert, Roseline; Vilain, Catheline; Waespe, Nicolas; Winship, Ingrid M; Evans, D Gareth; Brugieres, Laurence (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background Little is known about risks associated with germline SUFU pathogenic variants (PVs) known as a cancer predisposition syndrome. Methods To study tumour risks, we have analysed data of a large cohort of 45 ...
  • Canine Mammary Tumours Are Affected by Frequent Copy Number Aberrations, including Amplification of MYC and Loss of PTEN 
    Borge, Kaja Sverdrup; Nord, Silje; Van Loo, Peter; Lingjærde, Ole Christian; Gunnes, Gjermund; Alnæs, Grethe I Grenaker; Solvang, Hiroko Kato; Luders, Torben; Kristensen, Vessela N.; Børresen-Dale, Anne-Lise; Lingaas, Frode (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
    Background Copy number aberrations frequently occur during the development of many cancers. Such events affect dosage of involved genes and may cause further genomic instability and progression of cancer. In this survey, ...
  • Cardiac Structure and Function in Epilepsy Patients with Drug-Resistant Convulsive Seizures 
    Gonzalez, Alba; Haugaa, Kristina Ingrid Helena Hermann; Brekke, Pål Haugar; Hopp, Einar; Ørn, Stein; Alvestad, Silje; Taubøll, Erik; Aurlien, Dag (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    High frequency of convulsive seizures and long-lasting epilepsy are associated with an increased risk of sudden unexpected death in epilepsy (SUDEP). Structural changes in the myocardium have been described in SUDEP victims. ...
  • The Cardiac Ventricular 5-HT4 Receptor Is Functional in Late Foetal Development and Is Reactivated in Heart Failure 
    Brattelid, Trond; Qvigstad, Eirik; Moltzau, Lise Roman; Bekkevold, Silje Veslemøy; Sandnes, Dagny Lise; Birkeland, Jon Arne; Skomedal, Tor; Osnes, Jan-Bjørn; Sjaastad, Ivar; Levy, Finn Olav (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    A positive inotropic responsiveness to serotonin, mediated by 5-HT4 and 5-HT2A receptors, appears in the ventricle of rats with post-infarction congestive heart failure (HF) and pressure overload-induced hypertrophy. A ...
  • Care as intertextuality—from human condition to holistic device 
    Askheim, Clemet; Engebretsen, Eivind; Ødemark, John (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Since the Roman mythographer Hyginus composed the fable of Cura in the second century AD, it has been cited and reemployed in literary and philosophical texts by authors like Augustin, Herder, Goethe, Heidegger, Blumenberg ...