Browsing Institutt for biovitenskap by Title
Now showing items 2169-2188 of 2916
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)The intracellular movement and positioning of organelles and vesicles is mediated by the cytoskeleton and molecular motors. Small GTPases like Rab and Arf proteins are main regulators of intracellular transport by connecting ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Rab proteins compose the largest family of small GTPases and control the different steps of intracellular membrane traffic. More recently, they have been shown to also regulate cell signaling, division, survival, and ...
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Rab18 regulates focal adhesion dynamics by interacting with kinectin-1 at the endoplasmic reticulum (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)The members of the Rab family of small GTPases are molecular switches that regulate distinct steps in different membrane traffic pathways. In addition to this canonical function, Rabs can play a role in other processes, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Rab proteins are well known regulators of intracellular trafficking; however, more and more studies point to their function also in other cellular processes, including cell migration. In this work, we have performed an ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Rab proteins are master regulators of intracellular membrane trafficking, but they also contribute to cell division, signaling, polarization, and migration. The majority of the works describing the mechanisms used by Rab ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)Rab7a, a small GTPase of the Rab family, is localized to late endosomes and controls late endocytic trafficking. The discovery of several Rab7a interacting proteins revealed that Rab7a function is closely connected to ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Autophagy (macroautophagy) is a highly conserved eukaryotic degradation pathway in which cytosolic components and organelles are sequestered by specialized autophagic membranes and degraded through the lysosomal system. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Lysosomal signaling facilitates the migration of immune cells by releasing calcium to activate the actin-based motor myosin II at the cell rear. However, how the actomyosin cytoskeleton physically associates to lysosomes ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)To determine the present-day community composition of siliceous Rhizaria (Radiolaria and Phaeodaria) in Norwegian fjords, plankton tows were conducted in south-western and northern Norwegian fjords in September 2016. The ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Speciation encompasses a continuum over time from freely interbreeding populations to reproductively isolated species. Along this process, ecotypes – the result of local adaptation – may be on the road to new species. We ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)RAF kinases (ARAF, BRAF, and CRAF) are highly conserved enzymes that trigger the RAF-MEK1/2-ERK1/2 (MAPK) pathway upon activation of RAS. Despite enormous clinical interest, relatively little is known on the role of RAFs ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Invariant chain (Ii, CD74) is a type II transmembrane glycoprotein that acts as a chaperone and facilitates the folding and transport of MHC II chains. By assisting the assembly and subcellular targeting of MHC II complexes, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Real-time observation of adaptive evolution in the wild is rare and limited to cases of marked, often anthropogenic, environmental change. Here we present the case of a small population of reed warblers (Acrocephalus ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Fungi are evolutionary shape shifters and adapt quickly to new environments. Ectomycorrhizal (EM) symbioses are mutualistic associations between fungi and plants and have evolved repeatedly and independently across the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Connectivity of coral reef fish populations relies on successful dispersal of a pelagic larval phase. Pelagic larvae must exhibit high swimming abilities to overcome ocean and reef currents, but once settling onto the reef, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Freshwater acidification is characterised by elevated concentrations of aqueous aluminium. Global emissions of acidifying agents are reduced due to international agreements, and freshwater acidification has shifted from ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)We have previously shown that aberrant promoter methylation of ZNF331 is a potential biomarker for colorectal cancer detection with high sensitivity (71%) and specificity (98%). This finding was recently confirmed by others, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Crucian carp (Carassius carassius) survive without oxygen for several months, but it is unknown whether they are able to protect themselves from cell death normally caused by the absence, and particularly return, of oxygen. ...
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(Master thesis / Masteroppgave, 2020)An investigation of different factors that affect mapping accuracy
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Background The developing zebrafish is an emerging tool in nanomedicine, allowing non-invasive live imaging of the whole animal at higher resolution than is possible in the more commonly used mouse models. In addition, ...