The WEE1-inhibitor MK-1775 is currently in clinical trials as an anti-cancer drug. In response to DNA damage, human cells activate cell cycle checkpoints to temporarily halt cell cycle progression, and this helps facilitating ...

Genetic assimilation emerges from selection on phenotypic plasticity. Yet, commonly used quantitative genetics models of linear reaction norms considering intercept and slope as traits do not mimic the full process of ...

Teleost fishes comprise more than half of all vertebrate species, yet genomic data are only available for 0.2% of their diversity. Here, we present whole genome sequencing data for 66 new species of teleosts, vastly expanding ...

Elevated temperature causes metabolism and respiration to increase in poikilothermic organisms. We hypothesized that invertebrate consumers will therefore require increasingly carbon-rich diets in a warming environment ...

Yersinia pestis, the etiologic agent of the disease plague, has been implicated in three historical pandemics. These include the third pandemic of the 19th and 20th centuries, during which plague was spread around the ...

In aquaculture today, vaccination of farmed fish is successfully providing protection against many of the most common pathogens. However, while vaccines are most commonly given as a single injection, this is not the ideal ...