Browsing Institutt for biovitenskap by Title
Now showing items 1356-1375 of 1521
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2001)Type-B T cells raised against the immunodominant peptide in hen egg lysozyme (HEL(48-62)) do not respond to whole lysozyme, and this has been thought to indicate that peptide can bind to I-A(k) in different conformations. ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)The widespread occurrence of repetitive stretches of DNA in genomes of organisms across the tree of life imposes fundamental challenges for sequencing, genome assembly, and automated annotation of genes and proteins. This ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background: The WNT pathway regulates intestinal stem cells and is frequently disrupted in intestinal adenomas. The pathway contains several potential biotargets for interference, including the poly-ADP ribosyltransferase ...
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(Doctoral thesis / Doktoravhandling, 2020)Targeting the DNA damage response to selectively kill cancer cells is a topic of great interest in the field of cancer research. Inhibitors of the cell cycle checkpoint kinases WEE1, CHK1 and ATR have been developed, and ...
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(Master thesis / Masteroppgave, 2019)
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(Master thesis / Masteroppgave, 2013)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Monoclonal antibodies (mAbs) are valuable as research reagents, in diagnosis and in therapy. Their high specificity, the ease in production, favorable biophysical properties and the opportunity to engineer different ...
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Targeting vaccines to dendritic cells A functional analysis of human XCL1 and XCL2 in miceRestricted Access (Master thesis / Masteroppgave, 2013)The idea of targeting vaccines directly to antigen presenting cells to increase vaccine efficiency has received great attention in recent years, and so has the strategy of further tailoring the vaccine to elicit a desired ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2016)CD4+ T cells recognizing dietary gluten epitopes in the context of disease-associated human leukocyte antigen (HLA)-DQ2 or HLA-DQ8 molecules are the key players in celiac disease pathogenesis. Here, we conducted a large-scale ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Selection of biased T cell receptor (TCR) repertoires across individuals is seen in both infectious diseases and autoimmunity, but the underlying molecular basis leading to these shared repertoires remains unclear. Celiac ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)TCTP has been implicated in a plethora of important cellular processes related to cell growth, cell cycle progression, malignant transformation and inhibition of apoptosis. In addition to these intracellular functions, ...
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(Master thesis / Masteroppgave, 2017)
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2013)Kelps, seaweeds and seagrasses provide important ecosystem services in coastal areas, and loss of these macrophytes is a global concern. Recent surveys have documented severe declines in populations of the dominant kelp ...
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Temperature dependent toxicity of the neonicotinoid imidacloprid on survival and development in an arctic population of the Collembola Hypogastrura viaticaRestricted Access (Master thesis / Masteroppgave, 2020)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)1. Habitat selection is a complex process, which involves behavioural decisions guided by the multiple needs and constraints faced by individuals. Climate-induced changes in environmental conditions may alter those trade-offs ...
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(Master thesis / Masteroppgave, 2018)The responses in size, survival and other life-history traits in the cladoceran Daphnia magna were assessed at two temperatures (15 and 25ºC) across a calcium (Ca) gradient (0.5, 4 and 106 mg Ca/l) for two different clones ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Background Anthrax is a globally distributed disease affecting primarily herbivorous mammals. It is caused by the soil-dwelling and spore-forming bacterium Bacillus anthracis. The dormant B. anthracis spores ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)The Barents Sea system is often depicted as a simple food web in terms of number of dominant feeding links. The most conspicuous feeding link is between the Northeast Arctic cod Gadus morhua, the world's largest cod stock ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)Avoiding predators most often entails a food cost. For the Scandinavian brown bear (Ursus arctos), the hunting season coincides with the period of hyperphagia. Hunting mortality risk is not uniformly distributed throughout ...