Now showing items 1208-1227 of 1599

  • Villar, Jaime Otero; Jensen, Arne Johan; L'abee-Lund, Jan Henning; Stenseth, Nils Christian; Storvik, Geir Olve; Vøllestad, Leif Asbjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Many Atlantic salmon, Salmo salar, populations are decreasing throughout the species' distributional range probably due to several factors acting in concert. A number of studies have documented the influence of freshwater ...
  • Pharo, Heidi Dietrichson (Master thesis / Masteroppgave, 2014)
    Aberrant DNA methylation is one of the most common alterations in cancer, and a vast diversity of methods for its investigation exists. Quantitative methylation-specific PCR (qMSP) is frequently used to estimate the amounts ...
  • Tran, Trung (Doctoral thesis / Doktoravhandling, 2018)
    In this thesis, a general phosphoproteomics workflow was established by careful evaluation of the different steps for phosphopeptide enrichment. In addition, the application of two different collision energies for MS2 ...
  • Halvorson, Halvor M.; Sperfeld, Erik; Evans-White, Michelle, A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Resource quantity and quality are fundamental bottom-up constraints on consumers. Best understood in autotroph-based systems, co-occurrence of these constraints may be common but remains poorly studied in detrital-based ...
  • Kjos, Ingrid; Vestre, Katharina; Guadagno, Noemi Antonella; Distefano, Marita Borg; Progida, Cinzia (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2018)
    The intracellular movement and positioning of organelles and vesicles is mediated by the cytoskeleton and molecular motors. Small GTPases like Rab and Arf proteins are main regulators of intracellular transport by connecting ...
  • Guadagno, Noemi Antonella; Progida, Cinzia (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Rab proteins compose the largest family of small GTPases and control the different steps of intracellular membrane traffic. More recently, they have been shown to also regulate cell signaling, division, survival, and ...
  • Vestre, Katharina; Kjos, Ingrid; Guadagno, Noemi Antonella; Distefano, Marita Borg; Kohler, Felix; Fenaroli, Federico; Bakke, Oddmund; Progida, Cinzia (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Rab proteins are master regulators of intracellular membrane trafficking, but they also contribute to cell division, signaling, polarization, and migration. The majority of the works describing the mechanisms used by Rab ...
  • Margiotta, Azzurra; Progida, Cinzia; Bakke, Oddmund; Bucci, Cecilia (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Rab7a, a small GTPase of the Rab family, is localized to late endosomes and controls late endocytic trafficking. The discovery of several Rab7a interacting proteins revealed that Rab7a function is closely connected to ...
  • Kjos, Ingrid; Distefano, Marita Borg; Sætre, Frank Ove; Repnik, Urska; Holland, Petter; Jones, Arwyn T; Engedal, Nikolai; Simonsen, Anne; Bakke, Oddmund; Progida, Cinzia (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Autophagy (macroautophagy) is a highly conserved eukaryotic degradation pathway in which cytosolic components and organelles are sequestered by specialized autophagic membranes and degraded through the lysosomal system. ...
  • Brandrud, Marie Kristine; Paun, Ovidiu; Lorenzo, Maria Teresa; Nordal, Inger; Brysting, Anne Krag (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Speciation encompasses a continuum over time from freely interbreeding populations to reproductively isolated species. Along this process, ecotypes – the result of local adaptation – may be on the road to new species. We ...
  • Riegel, Kristina; Schlöder, Janine; Sobczak, Marco; Jonuleit, Helmut; Thiede, Bernd; Schild, Hansjörg; Rajalingam, Krishnaraj (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    RAF kinases (ARAF, BRAF, and CRAF) are highly conserved enzymes that trigger the RAF-MEK1/2-ERK1/2 (MAPK) pathway upon activation of RAS. Despite enormous clinical interest, relatively little is known on the role of RAFs ...
  • Sætre, Camilla Lo Cascio; Coleiro, Charles; Austad, Martin; Gauci, Mark; Sætre, Glenn-Peter; Voje, Kjetil L.; Eroukhmanoff, Fabrice (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Real-time observation of adaptive evolution in the wild is rare and limited to cases of marked, often anthropogenic, environmental change. Here we present the case of a small population of reed warblers (Acrocephalus ...
  • Hess, Jaqueline; Skrede, Inger; Chaib De Mares, Maryam; Hainaut, Matthieu; Henrissat, Bernard; Pringle, Anne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Fungi are evolutionary shape shifters and adapt quickly to new environments. Ectomycorrhizal (EM) symbioses are mutualistic associations between fungi and plants and have evolved repeatedly and independently across the ...
  • Vedeld, Hege M; Nesbakken, Arild; Lothe, Ragnhild A; Lind, Guro E (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    We have previously shown that aberrant promoter methylation of ZNF331 is a potential biomarker for colorectal cancer detection with high sensitivity (71%) and specificity (98%). This finding was recently confirmed by others, ...
  • Lefevre, Sjannie; Stecyk, Jonathan A. W.; Torp, May-Kristin; Løvold, Lisa Yuen; Sørensen, Christina; Johansen, Ida Beitnes; Stensløkken, Kåre-Olav; Couturier, Christine; Sloman, Katherine A.; Nilsson, Göran Erik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
    Crucian carp (Carassius carassius) survive without oxygen for several months, but it is unknown whether they are able to protect themselves from cell death normally caused by the absence, and particularly return, of oxygen. ...
  • Mousavi, Seyed Ali; Skjeldal, Frode Miltzow; Fønhus, Marita Sporstøl; Haugen, Linda Hofstad; Eskild, Winnie; Berg, Trond; Bakke, Oddmund (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background and Aims. Vascular endothelial growth factor (VEGF) receptors (VEGFR1 and VEGFR2) bind VEGF-A with high affinity. This study sought to determine the relative contributions of these two receptors to receptor-mediated ...
  • Shi, Jihua; Guo, Wen-Zhi; Jin, Yang; Zhang, Hua-Peng; Pang, Chun; Li, Jie; Line, Pål Dag; Zhang, Shui-Jun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Background The ERBB2 oncogene hypothesis is challenged in hepatocellular carcinoma (HCC) with the conflicting evidences of human epidermal growth factor receptor 2 (HER2) overexpression. HER2 could be a new target as a ...
  • Hoås, Helene Mykland (Master thesis / Group thesis / Masteroppgave / Gruppeoppgave, 2017)
  • Žliobaitė, Indrė; Fortelius, Mikael; Stenseth, Nils Christian (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    In the fossil record, taxa exhibit a regular pattern of waxing and waning of occupancy, range or diversity between their origin and extinction. This pattern appears to contradict the law of constant extinction1, which ...
  • Vike, Brit Karen (Master thesis / Masteroppgave, 2016)
    The regular movement of animals between summer and winter ranges, termed seasonal migration, is a common phenomenon among ungulates at northern latitudes. The most prominent hypothesis to explain seasonal migration is the ...