Browsing Institutt for molekylær biovitenskap ( -2012) by Title
Now showing items 132-151 of 343
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FcRn expression, ligands binding properties and its regulation in human immune cells and hepatocytes (Master thesis / Masteroppgave, 2007)ABSTRACT Expression and diverse functions of MHC class I related neonatal Fc receptor in different tissues is continually reported. To contribute to the understanding of how the receptor functions according to cell type, ...
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(Master thesis / Masteroppgave, 2005)The high densities of receptors found in synapses are crucial for effective transmission between a nerve and its target cell. At the neuromuscular junctions, acetylcholine is the transmitter substance and its receptor, the ...
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(Master thesis / Masteroppgave, 2009)Prostate cancer is one of the most frequently diagnosed cancers and second highest cause of death in patients who suffer from cancer in western countries. Much effort has been carried out to understand the molecular ...
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Functional analysis of STAMP1 and a putative interaction partner in prostate cancerRestricted Access (Master thesis / Masteroppgave, 2011)
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Functional characterization of a novel human methyltransferase and the generation of corresponding knockout human cell linesRestricted Access (Master thesis / Masteroppgave, 2010)This study investigates the function of a novel human protein, which, based on secondary structure prediction, belongs to class I of SAM-dependent methyltransferases (MTases). No specific functions or substrates have yet ...
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Functional in vitro and in vivo analysis of the Arabidopsis SET domain protein ASHR3Restricted Access (Master thesis / Masteroppgave, 2008)ABSTRACT The evolutionary conserved SET-domain is found in proteins encoded by more than 30 genes in Arabidopsis thaliana and is known to be involved in the epigenetic control of gene expression and organization of chromatin ...
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(Master thesis / Hovedoppgave, 2005)Vekstfaktorer og vekstfaktorreseptorer er med på å regulere vekst av celler via et nettverk av spesifikke intracellulære signalmekanismer. Binding av vekstfaktorer til reseptorer aktiverer reseptorene slik at signalkjeder ...
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(Master thesis / Masteroppgave, 2005)Histone lysine methylation is considered to be a relatively stable modification associated with important functions in epigenetic gene control and for organizing chromatin domains. Genes encoding mammalian homologues of ...
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(Master thesis / Masteroppgave, 2010)Ovarian carcinoma (OC), primary peritoneal carcinoma (PPC) and malignant mesothelioma (MM) are all highly aggressive tumors that share common morphological features in addition to being histogenetically related. It is of ...
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(Doctoral thesis / Doktoravhandling, 2008)Crucian carp, Carassius carassius, survives days to months without oxygen (anoxia). Still, during anoxia, it needs to keep the energy expenditure low, particularly in the brain, which has a high rate of ATP use mainly ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)Background Despite the fact that metastases are the leading cause of colorectal cancer deaths, little is known about the underlying molecular changes in these advanced disease stages. Few have studied the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Background Multiple epigenetic and genetic changes have been reported in colorectal tumors, but few of these have clinical impact. This study aims to pinpoint epigenetic markers that can discriminate between ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2008)Absolute tumor DNA copy numbers can currently be achieved only on a single gene basis by using fluorescence in situ hybridization (FISH). We present GeneCount, a method for genome-wide calculation of absolute copy numbers ...
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Genetisk og funksjonell studie av glykosyltransferase PglA i Neisseria gonorrhoeae og Neisseria lactamicaRestricted Access (Master thesis / Masteroppgave, 2010)Neisseria er en gruppe gram-negative bakterier som består av både patogene og ikke-patogene arter. Patogene Neisseria fører til store helseproblemer på verdensbasis; Neisseria meningitidis kan forårsake meningokokksykdom, ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)Atlantic cod (Gadus morhua) is a large, cold-adapted teleost that sustains long-standing commercial fisheries and incipient aquaculture. Here we present the genome sequence of Atlantic cod, showing evidence for complex ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)Background In many cell types, including the fission yeast Schizosaccharomyces pombe, a set of checkpoints are induced by perturbations of the cell cycle or by DNA damage. Many of the checkpoint responses ...
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(Master thesis / Masteroppgave, 2008)Abstract Glutamate is the major excitatory neurotransmitter in the mammalian central nervous system (CNS), and is inactivated by cellular uptake, mostly catalyzed by glutamate (excitatory amino acid) transporter subtype ...
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(Master thesis / Masteroppgave, 2005)Bacillus cereus ATCC 14579 was grown under different conditions, in different growth media, and the following parameters were investigated; cell number, pH,oxygen levels, glucose levels, cell morphology, proportions of ...
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Heterolog ekspresjon av immunitetsproteinet til to-peptidbakteriosinet lactococcin GRestricted Access (Master thesis / Masteroppgave, 2009)Bakteriosiner er ribosomalt syntetiserte, antimikrobielle peptider som produseres av en rekke bakteriearter. Lactococcin G er et bakteriosin som består av to peptider, kalt α og β, og produseres av melkesyrebakterien ...
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(Master thesis / Masteroppgave, 2006)37 kDa/67 kDa laminin reseptor (LR) er et protein som antas å fungere som en reseptor for prionproteinet, og kan være en mulig kofaktor i omgjøringen av det cellulære prionproteinet, PrPc, til en infeksiøs form, PrPsc, som ...