Browsing Institutt for biovitenskap by Title
Now showing items 2561-2580 of 2915
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background Mechanisms underlying genome 3D organization and domain formation in the mammalian nucleus are not completely understood. Multiple processes such as transcriptional compartmentalization, DNA loop ...
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(Master thesis / Masteroppgave, 2021)
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(Master thesis / Masteroppgave, 2023)
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(Master thesis / Masteroppgave, 2020)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)The widespread occurrence of repetitive stretches of DNA in genomes of organisms across the tree of life imposes fundamental challenges for sequencing, genome assembly, and automated annotation of genes and proteins. This ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)The objective of this study was to evaluate how the tank colours may change the effects of extreme temperature on the survival, growth, and quality of juvenile golden trevally (Gnathanodon speciosus). The experiment was ...
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(Master thesis / Masteroppgave, 2023)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Background: The WNT pathway regulates intestinal stem cells and is frequently disrupted in intestinal adenomas. The pathway contains several potential biotargets for interference, including the poly-ADP ribosyltransferase ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Background Despite the efforts to describe the molecular landscape of esophageal adenocarcinoma (EAC) and its precursor lesion Barrett’s esophagus (BE), discrepant findings are reported. Here, we investigated ...
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(Doctoral thesis / Doktoravhandling, 2020)Targeting the DNA damage response to selectively kill cancer cells is a topic of great interest in the field of cancer research. Inhibitors of the cell cycle checkpoint kinases WEE1, CHK1 and ATR have been developed, and ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)Therapy resistance is the major cause of cancer death. As patients respond heterogeneously, precision/personalized medicine needs to be considered, including the application of nanoparticles (NPs). The success of therapeutic ...
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(Master thesis / Masteroppgave, 2022)
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(Master thesis / Masteroppgave, 2019)
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Targeting ROCK1/2 blocks cell division and induces mitotic catastrophe in hepatocellular carcinoma (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)Background Rho-Associated kinases ROCK1 and ROCK2 have been extensively investigated in the pathogenesis of cardiovascular disease. However, their roles are not fully understood in carcinogenesis. In this study, we ...
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(Master thesis / Masteroppgave, 2013)
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(Master thesis / Masteroppgave, 2022)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Monoclonal antibodies (mAbs) are valuable as research reagents, in diagnosis and in therapy. Their high specificity, the ease in production, favorable biophysical properties and the opportunity to engineer different ...
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Targeting vaccines to dendritic cells A functional analysis of human XCL1 and XCL2 in miceRestricted Access (Master thesis / Masteroppgave, 2013)The idea of targeting vaccines directly to antigen presenting cells to increase vaccine efficiency has received great attention in recent years, and so has the strategy of further tailoring the vaccine to elicit a desired ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Taxonomy of fourteen very little known species of Nodosariinae Ehrenberg, 1838 in Icelandic waters is revised. Knowledge of these species in the North Atlantic relies mainly on studies in the late 19th and early 20th centuries, ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2016)CD4+ T cells recognizing dietary gluten epitopes in the context of disease-associated human leukocyte antigen (HLA)-DQ2 or HLA-DQ8 molecules are the key players in celiac disease pathogenesis. Here, we conducted a large-scale ...