Browsing Farmasøytisk institutt by Title

Now showing items 730-749 of 1934

  • «Går dette sammen?» Hvordan løses kompatibilitetsproblemer mellom intravenøse legemidler og parenteral ernæring på Nyfødtintensiv ved Barne- og ungdomsklinikken, Haukeland universitetssjukehus? En kvalitativ studie basert på flere metoderRestricted Access 
    Stojkovic, Slavisa (Master thesis / Masteroppgave, 2021)
  • Gellan Gum/Laponite Beads for the Modified Release of Drugs: Experimental and Modeling Study of Gastrointestinal Release 
    Adrover, Alessandra; Paolicelli, Patrizia; Petralito, Stefania; Di Muzio, Laura; Trilli, Jordan; Cesa, Stefania; Tho, Ingunn; Casadei, Maria Antonietta (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    In this study, gellan gum (GG), a natural polysaccharide, was used to fabricate spherical porous beads suitable as sustained drug delivery systems for oral administration. GG was cross-linked with calcium ions to prepare ...
  • Gene expression studies in Atlantic salmon (Salmo salar L.) : Effects of peroxisome proliferator-activated receptor agonists 
    Thi, Therese Mong Thuong Le (Master thesis / Hovedoppgave, 2007)
    ABSTRACT Since their discovery in the early 1990s, peroxisome proliferator-activated receptors (PPARs) have become an extremely important set of targets for drug discovery. The ligand-induced transcription factors that ...
  • Generation and Characterization of Novel Zebrafish Models for Epileptogenesis 
    Nguyen, Anna Thao Thanh (Master thesis / Masteroppgave, 2017)
    Epilepsy is one of the most common chronic neurological disorders affecting more than 50 million people worldwide. The disorder is considered a major health problem with increased risk of mortality and co-morbidities. The ...
  • Generic Liquid Membranes for Electromembrane Extraction of Bases with Low or Moderate Hydrophilicity 
    Zhou, Chen; Dowlatshah, Samira; Hay, Anne Oldeide; Schüller, Maria; Pedersen-Bjergaard, Stig; Hansen, Frederik Andre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    For the first time, this paper introduces the idea of generic extraction conditions in electromembrane extraction (EME), where the selection of the liquid membrane is based on the charge (z) and hydrophobicity (log P) of ...
  • Generisk substitusjon av legemidler på sykehus 
    Hopen, Heidi Skjønhaug (Master thesis / Masteroppgave, 2009)
    1. mai 2008 ble den nye forskriften om legemiddelhåndtering innført i Norge. Dette åpnet for at generisk substitusjon av legemidler kan foretas av helsepersonell i sykehus og andre helseforetak. Substitusjon av legemidler ...
  • Generisk takrolimus i eldre nyretransplanterte pasienter 
    Olsen Ingerø, Aleksander (Master thesis / Masteroppgave, 2014)
    Introduksjon Tacrolimus (Tac) er en potent immunosuppressiv som brukes rutinemessig i nyretransplantasjon. Tac doseres morgen og kveld, karakteriseres av et smalt terapeutisk vindu og styres etter trough/C0-målinger. For ...
  • Generiske væskemembraner i EME for syrer 
    Gaznawi, Somayeh (Master thesis / Masteroppgave, 2023)
  • Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness 
    Cheng, Weiqiu; Frei, Oleksandr; van der Meer, Dennis; Wang, Yunpeng; O`Connell, Kevin; Chu, Yunhan; Bahrami, Shahram; Shadrin, Alexey A.; Alnæs, Dag; Hindley, Guy Frederick Lanyon; Lin, Aihua; Karadag, Naz; Fan, Chun Chieh; Westlye, Lars Tjelta; Kaufmann, Tobias; Molden, Espen; Dale, Anders M.; Djurovic, Srdjan; Smeland, Olav Bjerkehagen; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
    Importance Schizophrenia is a complex heritable disorder associated with many genetic variants, each with a small effect. While cortical differences between patients with schizophrenia and healthy controls are consistently ...
  • Genetic nurture versus genetic transmission of risk for ADHD traits in the Norwegian Mother, Father and Child Cohort Study 
    Pingault, Jean-Baptiste; Barkhuizen, Wikus; Wang, Biyao; Hannigan, Laurie John; Eilertsen, Espen Moen; Corfield, Elizabeth Claire; Andreassen, Ole; Ask, Helga; Tesli, Martin Steen; Askeland, Ragna Bugge; Davey Smith, George; Stoltenberg, Camilla; Davies, Neil M.; Reichborn-Kjennerud, Ted; Ystrøm, Eivind; Havdahl, Alexandra (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract Identifying mechanisms underlying the intergenerational transmission of risk for attention-deficit/hyperactivity disorder (ADHD) traits can inform interventions and provide insights into the role of parents in ...
  • Genetic Susceptibility to Drug Teratogenicity: A Systematic Literature Review 
    Gomes, Julia do Amaral; Olstad, Emilie Willoch; Kowalski, Thayne Woycinck; Gervin, Kristina; Vianna, Fernanda Sales Luiz; Schüler-Faccini, Lavínia; Nordeng, Hedvig Marie Egeland (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
    Since the 1960s, drugs have been known to cause teratogenic effects in humans. Such teratogenicity has been postulated to be influenced by genetics. The aim of this review was to provide an overview of the current knowledge ...
  • The genome sequence of Atlantic cod reveals a unique immune system 
    Star, Bastiaan; Nederbragt, Alexander Johan; Jentoft, Sissel; Grimholt, Unni; Malmstrøm, Martin; Gregers, Tone Fredsvik; Rounge, Trine Ballestad; Paulsen, Jonas; Solbakken, Monica Hongrø; Sharma, Animesh; Wetten, Ola Frang; Lanzén, Anders; Winer, Roger; Knight, James; Vogel, Jan-Hinnerk; Aken, Bronwen; Andersen, Øivind; Lagesen, Karin; Tooming-Klunderud, Ave; Edvardsen, Rolf; Kirubakaran, G. Tina; Espelund, Mari; Nepal, Chirag; Previti, A. Christopher; Karlsen, Bård Ove; Moum, Truls; Skage, Morten; Berg, Paul Ragnar; Gjøen, Tor; Kuhl, Heiner; Thorsen, Jim; Malde, Ketil; Reinhardt, Richard; Du, Lei; Johansen, Steinar Daae; Searle, Steve; Lien, Sigbjørn; Nilsen, Frank; Jonassen, Inge; Omholt, Stig W; Stenseth, Nils Christian; Jakobsen, Kjetill Sigurd (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
    Atlantic cod (Gadus morhua) is a large, cold-adapted teleost that sustains long-standing commercial fisheries and incipient aquaculture. Here we present the genome sequence of Atlantic cod, showing evidence for complex ...
  • Genomic Stratification of Clozapine Prescription Patterns Using Schizophrenia Polygenic Scores 
    Kappel, Djenifer B.; Legge, Sophie E.; Hubbard, Leon; Willcocks, Isabella R.; O'Connell, Kevin Sean; Smith, Robert Løvsletten; Molden, Espen; Andreassen, Ole; King, Adrian; Jansen, John; Helthuis, Marinka; Owen, Michael J.; O'Donovan, Michael C.; Walters, James T.R.; Pardiñas, Antonio F. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Treatment-resistant schizophrenia affects approximately 30% of individuals with the disorder. Clozapine is the medication of choice in treatment-resistant schizophrenia, but optimizing administration and dose ...
  • Genomiske ustabilitetsmekanismer : Konstruksjon og undersøkelse av konsekvensene av en mutasjon i PCNA 
    Larsen, Kristine Paulseth (Master thesis / Masteroppgave, 2013)
    En viktig faktor som kan føre til kreftutvikling er genomisk ustabilitet. Genomisk ustabilitet kan være forårsaket av flere faktorer, blant annet økt forekomst av dobbeltrådbrudd, eller at reparasjonsmekanismer i DNA ikke ...
  • Genotoksisk effekt av glutamat og glukokortikoider på nevronale cellerRestricted Access 
    Akwagoh, Sinota Angyesom (Master thesis / Masteroppgave, 2013)
    Mitokondrier er viktige for funksjonen av nerveceller, noe som illustreres ved at mitokondriell dysfunksjon er observert ved mange nevrodegenerative sykdommer. Mitokondriell dysfunksjon kan inkludere svekket biokjemisk ...
  • Genotyping av pasienter behandlet med selektive serotoninreopptakshemmere 
    Solhaug, Vigdis; Haslemo, Tore; Kringen, Marianne Kristiansen; Molden, Espen; Dietrichs, Erik Sveberg (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    BAKGRUNN Selektive serotoninreopptakshemmere (SSRI) brukes av over 180 000 mennesker i Norge. Enzymene CYP2D6 og CYP2C19 er sentrale i metabolismen av SSRI-antidepressiver. Serotonintransportøren kodet av SLC6A4 kan ha ...
  • Genvarianter med mulig betydning for legemiddelrespons ved stamcelletransplantasjon 
    Resløkken, Marthe (Master thesis / Masteroppgave, 2016)
    Innledning: Busulfan (BU) og syklofosfamid (Cy) inngår i standard forbehandlingsregime i forbindelse med allogen stamcelletransplantasjon (HSCT). Doseringen av disse cytostatika er krevende, da for lav eksponering kan øke ...
  • Global mRNA decay analysis at single nucleotide resolution reveals segmental and positional degradation patterns in a Gram-positive bacterium 
    Kristoffersen, Simen M; Haase, Chad; Weil, M R; Passalacqua, Karla D; Niazi, Faheem; Hutchison, Stephen K; Desany, Brian; Kolstø, Anne-Brit; Tourasse, Nicolas J; Read, Timothy D; Økstad, Ole A (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
    Background Recent years have shown a marked increase in the use of next-generation sequencing technologies for quantification of gene expression (RNA sequencing, RNA-Seq). The expression level of a gene is ...
  • Global variability analysis of mRNA and protein concentrations across and within human tissues 
    Wegler, Christine; Ölander, Magnus; Wisniewski, JR; Lundquist, Patrick; Zettl, K; Åsberg, Anders; Hjelmesæth, Jøran; Andersson, Tommy B; Artursson, Per (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
    Abstract Genes and proteins show variable expression patterns throughout the human body. However, it is not clear whether relative differences in mRNA concentrations are retained on the protein level. Furthermore, ...
  • Glomerular proteomic profiling reveals early differences between preexisting and de novo type 2 diabetes in human renal allografts 
    Kipp, Anne; Marti, Hans-Peter; Babickova, Janka; Nakken, Sigrid; Leh, Sabine; Halden, Thea A. S.; Jenssen, Trond; Vikse, Bjørn E.; Åsberg, Anders; Spagnoli, Giulio; Furriol, Jessica (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Diabetes mellitus (DM), either preexisting or developing after transplantation, remains a crucial clinical problem in kidney transplantation. To obtain insights into the molecular mechanisms ...