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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
A fusion gene is a hybrid gene consisting of parts from two previously independent genes. Chromosomal rearrangements leading to gene breakage are frequent in high-grade serous ovarian carcinomas ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2002)
To identify phosphoproteins that might play a role in naringin-sensitive hepatocellular cytoskeletal disruption and apoptosis induced by algal toxins, hepatocyte extracts were separated by gel electrophoresis and immunostained ...
Characterization of the human RFX transcription factor family by regulatory and target gene analysis
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Evolutionarily conserved RFX transcription factors (TFs) regulate their target genes through a DNA sequence motif called the X-box. Thereby they regulate cellular specialization and terminal ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
The catalytic mechanism of the cyclic amidohydrolase isatin hydrolase depends on a catalytically active manganese in the substrate-binding pocket. The Mn2+ ion is bound by a motif also present in other metal dependent ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Intercellular communication is pivotal in optimizing and synchronizing cellular responses to keep homeostasis and to respond adequately to external stimuli. In the central nervous system (CNS), glutamatergic and GABAergic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2024)
Background
Cardiovascular disease is a major cause of mortality and morbidity worldwide, and primary prevention efforts are poorly developed in people at high cardiovascular risk. On this background, we ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Cultured epidermal cell sheets (CECS) are used in regenerative medicine in patients with burns, and have potential to treat limbal stem cell deficiency (LSCD), as demonstrated in animal models. Despite widespread use, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
There are several treatment modalities for unresectable neuroendocrine tumors. Traditionally, the aim of these treatments has been to reduce the tumor load; referred to as objective response (OR). Less emphasis ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
The six transmembrane protein of prostate 2 (STAMP2) is an androgen‐regulated gene whose mRNA expression is increased in prostate cancer (PCa). Here, we show that STAMP2 protein expression is increased in human PCa compared ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Background Copy number aberrations frequently occur during the development of many cancers. Such events affect dosage of involved genes and may cause further genomic instability and progression of cancer. In this survey, ...