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(Doctoral thesis / Doktoravhandling, 2019)
This thesis develops and exploits methodology within network science, driven by important applications. By use of large-scale simulations and high-quality data, we demonstrate how network science can contribute to understanding ...
(Doctoral thesis / Doktoravhandling, 2008)
Appropriate T cell signaling is essential for the function of the human immune system. T cells regulate and direct the body’s response to foreign pathogens such as virus and bacteria, or threats from within in the form of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Background: To compare pregnancy complications and birth outcomes for women experiencing nausea and vomiting in pregnancy, or nausea only, with symptom-free women.
Methods: Pregnancies from the Norwegian Mother and Child ...
(Doctoral thesis / Doktoravhandling, 2017)
Metabolic syndrome (MetS) is a cluster of risk factors for cardiovascular disease that include abdominal obesity, dyslipidemia, hyperglycemia and hypertension. Fish consumption may be a useful component when aiming to ...
(Doctoral thesis / Doktoravhandling, 2018)
A major challenge for understanding the brain in health and disease is related to combining information about the brain from many different sources. Spatial analysis and comparison of 2D and 3D brain images with the aim ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background & aims: The effect of lycopene-containing foods in prostate cancer development remains undetermined. We tested whether a lycopene-rich tomato intervention could reduce the levels of prostate specific antigen ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The effects of rickets on children recovery from severe acute malnutrition (SAM) are unknown. Rickets may affect both growth and susceptibility to infectious diseases. We investigated the associations of clinically diagnosed ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The establishment of the Determinants of Diet and Physical Activity (DEDIPAC) Knowledge Hub, 2013–2016, was the first action taken by the ‘Healthy Diet for a Healthy Life’ European Joint Programming Initiative. DEDIPAC ...
(Doctoral thesis / Doktoravhandling, 2008)
Neurons conduct electrical signals, and signals pass from one neuron to the next by the use of chemical substances in specialized contacts, synapses. In most synapses, the transmitter is the amino acid glutamate. <br>
A ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The concept of foetal programming (FP) originated from human epidemiological studies, where foetal life nutrition was linked to health and disease status later in life. Since the proposal of this phenomenon, it has been ...
(Master thesis / Masteroppgave, 2013)
Bakgrunn: Pasienter i hemodialyse har høy risiko for ernæringsrelaterte problemer, både på grunn av nyresykdommen i seg selv og restriksjonene som innføres som en del av behandlingen. Kostrestriksjoner kan føre til et ...
(Master thesis / Masteroppgave, 2013)
Bakgrunn: Vitamin D har mange viktige funksjoner i kroppen, og ved mangel kan dette påvirke benhelsen, immunforsvaret og muskelfunksjon. De fleste studiene på effekten av vitamin D tilskudd på muskelfunskjon er gjort på ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background & aims: Bioelectrical impedance analysis (BIA) is an accessible and cheap method to measure fat-free mass (FFM). However, BIA estimates are subject to uncertainty in patient populations with altered body composition ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
A resurgence has taken place in recent years in the use of the extracellularly recorded local field potential (LFP) to investigate neural network activity. To probe monosynaptic thalamic activation of cortical postsynaptic ...
(Doctoral thesis / Doktoravhandling, 2016)
Faktorer som assosierer med et varig vekttap etter et organisert vektreduksjonskurs Restricted Access
(Master thesis / Masteroppgave, 2013)
Bakgrunn og mål: Overvekt og fedme er i dag en av de store folkehelseutfordringene. Mange prøver å gå ned i vekt og flere ved deltakelse i et organisert vektreduksjonsprogram. Flertallet som forsøker å gå ned i vekt lykkes. ...
(Doctoral thesis / Doktoravhandling, 2012)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
This study assessed the prevalence and risk factors associated with underweight, stunting and wasting among children aged 0–24 months in six districts of Kilimanjaro region, northern Tanzania. A cross-sectional population-based ...
(Doctoral thesis / Doktoravhandling, 2022)
Human adipose tissue depots are physiologically different, with distinct metabolic properties and contributions to disease. The underlying mechanisms for these differences are yet to be uncovered. Large-scale transcriptomic ...
(Master thesis / Masteroppgave, 2013)
Background and aims: The prevalence of overweight and obesity rises despite that many individuals tries to achieve a permanent weight loss. There are several different strategies available to achieve weight loss and weight ...
(Master thesis / Masteroppgave, 2008)
Background: Sugar intake has increased substantially in most parts of the world over the past 50 years. Soft drinks seem to be the largest contributor to this increase. A high intake of sugar is correlated with tooth decay, ...
(Master thesis / Masteroppgave, 2008)
Epidemiological studies have shown that a high intake of fruits and vegetables is associated with a reduced risk of chronic diseases. The mechanisms behind these beneficial effects are not fully understood, but it is widely ...
(Master thesis / Masteroppgave, 2008)
Summary
Patients with familial hypercholesterolemia (FH) have an increased risk of premature atherosclerosis and coronary artery disease (CAD). Recently, inflammation has been suggested to play a major role in the development ...
(Master thesis / Masteroppgave, 2008)
Aims
Several studies have reported an association between a diet low in fruits, vegetables, vitamin C and overweight and the presence of asthma. The primary aim of the present study was to compare the intake of nutrients ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
NutritionDay is a yearly point-prevalence study of malnutrition in hospitals from more than 50 countries. The aim of the present study was to quantify the frequency of malnutrition and the proportion of malnourished patients ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
World Health Organization (WHO) recommends exclusive breastfeeding (EBF) as the optimal way to feed infants below 6 months of age. The benefits of EBF are well documented. However, in Tanzania, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Innovations for undernourished pregnant women that improve newborn survival and anthropometry are needed to achieve the Sustainable Development Goals 1 and 3. This study tested the hypothesis that a combination ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
The world is continuously urbanising, resulting in clusters of densely populated urban areas and more sparsely populated rural areas. We propose a method for generating spatial fields with controllable levels of clustering ...
(Doctoral thesis / Doktoravhandling, 2008)
In observational epidemiology many studies rely on self-reported exposure information, which is prone to measurement errors and missing values. This may subsequently lead to bias in relative risk estimates of disease or ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
More than one third of Norwegian women and men between 20 and 40 years of age have elevated cholesterol concentration. Parental metabolic health around conception or during pregnancy may affect ...
(Master thesis / Masteroppgave, 2018)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Gaussian graphical models are useful tools for exploring network structures in multivariate normal data. In this paper we are interested in situations where data show departures from Gaussianity, therefore requiring ...
(Doctoral thesis / Doktoravhandling, 2020)
Pharmacogenomic screens for personalized cancer therapy are the focused biomedical application in this thesis. Due to the complex relationships between targeted cancer drugs and high-dimensional genomic predictors, we have ...
Effekten av magnesium og kalsium/vitamin-D tilskudd i 28 dager på kalsiumregulerende hormoner og beinparametre hos kvinner over 70 år. : En pilotstudie Restricted Access
(Master thesis / Masteroppgave, 2007)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background: Thought field therapy (TFT) is used for many psychiatric conditions, but its efficacy has not been sufficiently documented. Hence, there is a need for studies comparing TFT to well-established treatments. This ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Dietary fat is an essential macronutrient. However, saturated fact has been associated with negative health outcomes including cardiovascular disease. Shifting consumption from saturated fat to ...
(Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
Context
Quality of life (QoL) and depression are important patient-reported outcomes in cancer care. However, the relative importance of depression severity in predicting QoL remains unclear because of few methodologically ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
More than 14 % of Ugandan children are orphaned and many live in children’s homes. Ugandan authorities have targeted adolescent girls as a priority group for nutrition interventions as safeguarding ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Fish consumption may prevent or improve metabolic health. The aim of this study was to identify associations between fish consumption, both fatty and lean, and metabolic syndrome and its ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Early adulthood is a period associated with poor diet and rapid weight gain. This is also an age of transition, including environmental, social and lifestyle changes which may be associated with ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
Background
Policy frameworks focusing on policy implementation may vary in terms of their scope, included constructs, relationships between the constructs, and context factors. Although multiple policy ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Doctor –certified sick leave is prevalent in the health and social sector. We examined whether the higher risk of doctor-certified sick leave in women in health and social occupations compared ...
(Doctoral thesis / Doktoravhandling, 2016)
Human Rights Dimensions of Food, Health and Care in Selected Children s Homes in Kampala, Uganda – Experiences of Female Adolescent Residents as Rights-holders Restricted Access
(Master thesis / Masteroppgave, 2014)
Background: More than 14 percent of children in Uganda are orphaned, and many of them live in children s homes. Very little information exists regarding how these homes are operated and what the conditions in these homes ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Background
Fish consumption may have a role in reducing the prevalence of metabolic syndrome (MetS). The aim of this study was to identify associations between fish consumption and MetS and its components, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Understanding the determinants associated with prediabetes and type 2 diabetes in coronary patients may help to individualize treatment and modelling interventions. We sought to identify ...
Risk Factors for Cardiovascular Disease among Taxi Drivers in Oslo. A nine year follow-up study. Restricted Access
(Master thesis / Masteroppgave, 2014)
(Master thesis / Masteroppgave, 2014)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
Background
The endovascular treatment procedure in tandem occlusions (TO) is complex compared to single occlusion (SO) and optimal management remains uncertain. The aim of this study was to identify clinical ...
Dietary intake of impoverished pregnant women in the rural Mangochi district of Malawi Restricted Access
(Master thesis / Masteroppgave, 2014)
(Doctoral thesis / Doktoravhandling, 2016)
GABA and glutamate transporter proteins are important in relation to epilepsy because they represent the mechanisms that keep the extracellular concentrations of GABA and dicarboxylic amino acids low. GABA and glutamate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Background
Multi-item rating scales for depression informs about the level of depression, but does not allow individuals to state by self-evaluation whether they feel depressed or not. The insider perspective ...
(Master thesis / Masteroppgave, 2019)
(Master thesis / Masteroppgave, 2007)
Summary
Background: The evidence for a relationship between maternal nutritional status during pregnancy and future health of her unborn child is now ample. The different factors that may link fetal development and growth ...
(Master thesis / Masteroppgave, 2008)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
The comet assay has developed over the past 30 years and today, a variety of different DNA lesions and DNA repair can be measured by different versions of the assay (Collins, 2004). In the final step of the method, an image ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2005)
RNA interference (RNAi) has become an invaluable tool for functional genomics. A critical use of this tool depends on an understanding of the factors that determine the specificity and activity of the active agent, small ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Patients’ knowledge about psoriasis and its treatment has been randomly studied previously. The aim of the study is to investigate patients’ knowledge about psoriasis in relation to undergoing patient education in the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background Fruit and vegetable intake has been found to reduce the risk of cardiovascular disease, certain types of cancer and diabetes mellitus. It is possible that antioxidants play a large part in this protective effect. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Genome-wide sequencing technologies enable investigations of the structural properties of the genome in various spatial dimensions. Here, we review computational techniques developed to model the three-dimensional genome ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background
Previous studies suggest that persistent exposure to social stress in mammals may be associated with multiple physiological effects. Here, we examine the effects of social stress in rats, i.e. repeated social ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
α2-adrenoceptor-activation lowers central sympathetic output, peripheral, vesicular norepinephrine release, epinephrine secretion and modulates vascular tension. We previously demonstrated that α2-adrenoceptor-mediated ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
α2-Adrenoceptors lower central sympathetic output and peripheral catecholamine release, and thus may prevent sympathetic hyperactivity and hypertension. α2AR also influence vascular tension. These α2AR are malfunctioning ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Peripheral norepinephrine release is facilitated by presynaptic β-adrenoceptors (AR), believed to involve the β2-subtype exclusively. However, β1-selective blockers are the most commonly used β-blockers in hypertension. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
Sympathetic hyperactivity and parasympathetic insufficiency characterize blood pressure (BP) control in genetic hypertension. This shift is difficult to investigate in anesthetized rats. Here we present a pharmacological ...
(Doctoral thesis / Doktoravhandling, 2015)
The thesis describes the electrical activity in nerve cells (motoneurons) that control the deep back muscles in humans. The experiments were conducted using thin wire electrodes that were implanted deep in the spinal muscles ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Biomarkers of nutrient intake or nutrient status are important objective measures of foods/nutrients as one of the most important environmental factors people are exposed to. It is very difficult to obtain accurate data ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Background Few studies have focused on fatigue in myasthenia gravis (MG), and fatigue in relation to the autonomic system has never been systematically explored in these patients. The study aimed to document the prevalence ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
The system N transporter SN1 (also known as SNAT3) is enriched on perisynaptic astroglial cell membranes. SN1 mediates electroneutral and bidirectional glutamine transport, and regulates the intracellular as well as the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Knowledge of illness perception may aid the identification of groups of patients with a higher risk of coping
poorly with the demands of their illness. This study aims to investigate associations between illness perception, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Here, the influence of β3-adrenoceptors on catecholamine release in normotensive and spontaneously hypertensive rats was analyzed. Blood pressure was recorded through a femoral artery catheter, and cardiac output by ascending ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Cobalamin and folate are essential micronutrients and are important in DNA and RNA synthesis, cell proliferation, growth, hematopoiesis, and cognitive function. However, data on cobalamin and folate status are ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2016)
Background Changes in electroencephalography (EEG) voltage range are used to monitor the depth of anaesthesia, as well as predict outcome after hypoxia-ischaemia in neonates. Xenon is being investigated as a potential ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Neonatal hypoxic‐ischemic encephalopathy (HIE) is associated with alterations in cerebral blood flow (CBF) as a result of perinatal asphyxia. The extent to which CBF changes contribute to injury, and whether treatments ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
Objective In women, the risk for non-communicable diseases increases after menopause. We aimed to identify major dietary patterns and study their associations with nutrient intake, sociodemographic factors and risk factors ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: Compared to food patterns, nutrient patterns have been rarely used particularly at international level. We studied, in the context of a multi-center study with heterogeneous data, the methodological challenges ...
(Doctoral thesis / Doktoravhandling, 2017)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
Lack of Hepatitis C virus (HCV) incidence data in (Norwegian) high-risk groups impedes the ability to make informed decisions on prevention measures. Thus we rely on modelling to estimate the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
In the dairy breeding industry, prediction of bull fertility in artificial insemination (AI) is important for efficient and economically sustainable production. However, it is challenging to identify bulls with superior ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
The three-dimensional (3D) structure of the genome is important for orchestration of gene expression and cell differentiation. While mapping genomes in 3D has for a long time been elusive, recent adaptations of high-throughput ...
(Doctoral thesis / Doktoravhandling, 2020)
The three-dimensional (3D) organization of chromatin in the mammalian cell nucleus plays an important role in the regulation of gene expression. In her Ph.D. thesis, Anna Frida Forsberg has investigated the impact of ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2014)
Blood pressure is a critical determinant of cardiovascular morbidity and mortality. It is affected by environmental factors, but has a strong heritable component. Despite recent large genome-wide association studies, few ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Objective: Neurocognitive impairment is commonly reported at onset of psychotic disorders. However, the long-term neurocognitive course remains largely uninvestigated in first episode psychosis (FEP) and the relationship ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Background
This is a six-year prospective follow-up of a former cross sectional study of suicide attempters in a sample of treatment-seeking substance-dependent patients. The aims were to explore the frequency ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2007)
Background
Communication training builds on the assumption that understanding of the concepts related to professional communication facilitates the training. We know little about whether students' knowledge ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Background
Self-evaluations of mental health problems may be a useful complement to diagnostic assessment, but are less frequently used. This study investigated the prevalence of self-evaluated current and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background
There is a lack of comprehensive patient-datasets regarding prevalence of severe hypertriglyceridemia (sHTG; triglycerides ≥10 mmol/L), frequency of co-morbidities, gene mutations, and gene ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2009)
Vaccines using dendritic cells (DCs) harboring leukemic antigens to stimulate T cells is a possible treatment of acute myeloid leukemia (AML). Limitations of breaking tolerance to leukemic cells and lack of specific ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Aquaporin-4 (AQP4) water channels are concentrated in astrocytic endfoot membranes at the brain–blood and brain–cerebrospinal fluid interfaces. The mechanisms underpinning the polarized distribution of AQP4 are poorly ...
(Master thesis / Masteroppgave, 2015)
(Master thesis / Masteroppgave, 2015)
Formål: Hovedformålet med denne masteroppgaven var å vurdere den relative validiteten til et kort matvarefrekvensskjema (NKR-spørreskjemaet) som brukes i Typisk norsk-studien (TNS) blant pasienter behandlet for tykk- og ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
Rheumatoid arthritis (RA) is a long-term disease that leads to inflammation of the joints and surrounding tissues. Natural killer(NK) cells are an important part of the innate immune system and are responsible for the first ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Crucian carp are unusual among vertebrates in surviving extended periods in the complete absence of molecular oxygen. During this time cardiac output is maintained though these mechanisms are not well understood. Using a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background: There is a need for valid and comprehensive measures of parental influence on children’s energy balance-related behaviours (EBRB). Such measures should be based on a theoretical framework, acknowledging the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
Background: Polychlorinated biphenyls (PCBs) are a class of organic compounds that bioaccumulate due to their chemical stability and lipophilic properties. Humans are prenatally exposed via trans-placental transfer, through ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Nondirective meditation techniques are practiced with a relaxed focus of attention that permits spontaneously occurring thoughts, images, sensations, memories, and emotions to emerge and pass freely, without any expectation ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
The T cell specific adapter protein (TSAd) is expressed in activated T cells and NK cells. While TSAd is beginning to emerge as a critical regulator of Lck and Itk activity in T cells, its role in NK cells has not yet been ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2012)
The process of radiationless energy transfer from a chromophore in an excited electronic state (the donor ) to another chromophore (an acceptor ), in which the energy released by the donor effects an electronic transition, ...