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dc.date.accessioned2020-06-04T18:28:29Z
dc.date.available2020-06-04T18:28:29Z
dc.date.created2019-03-29T13:40:21Z
dc.date.issued2019
dc.identifier.citationThorsen, Inga Strand Bleskestad, Inger Hjørdis Åsberg, Anders Hartmann, Anders Skadberg, Øyvind Brede, Cato Ueland, Thor Pasch, Andreas Reisæter, Anna Varberg Gøransson, Lasse . Vitamin D as a risk factor for patient survival after kidney transplantation: A prospective observational cohort study. Clinical Transplantation. 2019, 33:e13517(5), 1-13
dc.identifier.urihttp://hdl.handle.net/10852/76639
dc.description.abstractBackground Short‐term survival after kidney transplantation is excellent, but long‐term survival remains low and is equivalent to non‐end‐stage renal disease patients with many invasive malignancies. The aim of the study was to explore vitamin D status in the early phase after transplantation as a prognostic marker for long‐term graft and patient survival. Methods All first‐time kidney transplant recipients between October 2007 and October 2012 in Norway were included. Vitamin D was measured 10 weeks post‐transplant. Information on graft failure and death was obtained from the Norwegian Renal Registry. Results Seven hundred and sixty‐two first‐time kidney transplant recipients were included, with a median age of 57 years and a median follow‐up of 82 months. In the follow‐up period, there were 172 graft failures (23%) and 118 deaths (15%). Eighty‐six percent of the transplant recipients with sufficient vitamin D levels were alive with a well‐functioning graft after 5 years using Kaplan‐Meier survival estimates, compared with 79% and 76% of the patients with vitamin D deficiency and insufficiency, respectively (P = 0.006). Conclusion In a nation‐wide cohort of 762 first‐time kidney transplant recipients, long‐term graft and patient survival were better in recipients with vitamin D sufficiency 10 weeks post‐transplant compared with those with vitamin D deficiency and insufficiency.
dc.languageEN
dc.titleVitamin D as a risk factor for patient survival after kidney transplantation: A prospective observational cohort study
dc.typeJournal article
dc.creator.authorThorsen, Inga Strand
dc.creator.authorBleskestad, Inger Hjørdis
dc.creator.authorÅsberg, Anders
dc.creator.authorHartmann, Anders
dc.creator.authorSkadberg, Øyvind
dc.creator.authorBrede, Cato
dc.creator.authorUeland, Thor
dc.creator.authorPasch, Andreas
dc.creator.authorReisæter, Anna Varberg
dc.creator.authorGøransson, Lasse
cristin.unitcode185,15,23,30
cristin.unitnameFarmakologi og farmasøytisk biovitenskap
cristin.ispublishedtrue
cristin.fulltextpostprint
cristin.qualitycode1
dc.identifier.cristin1688890
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Clinical Transplantation&rft.volume=33:e13517&rft.spage=1&rft.date=2019
dc.identifier.jtitleClinical Transplantation
dc.identifier.volume33
dc.identifier.issue5
dc.identifier.doihttps://doi.org/10.1111/ctr.13517
dc.identifier.urnURN:NBN:no-79769
dc.type.documentTidsskriftartikkel
dc.type.peerreviewedPeer reviewed
dc.source.issn0902-0063
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/76639/5/OUTCOMEFINAL.pdf
dc.type.versionAcceptedVersion
cristin.articleide13517


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