Browsing Psykologisk institutt by Title
Now showing items 1633-1652 of 4384
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Abstract The difference between chronological age and the apparent age of the brain estimated from brain imaging data—the brain age gap (BAG)—is widely considered a general indicator of brain health. Converging evidence ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2019)Aims/hypothesis MODY can be wrongly diagnosed as type 1 diabetes in children. We aimed to find the prevalence of MODY in a nationwide population-based registry of childhood diabetes. Methods Using next-generation ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)Importance Schizophrenia is a complex heritable disorder associated with many genetic variants, each with a small effect. While cortical differences between patients with schizophrenia and healthy controls are consistently ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Autism spectrum disorder (autism) is a heterogeneous group of neurodevelopmental conditions characterized by early childhood-onset impairments in communication and social interaction alongside restricted and repetitive ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)General cognitive function is substantially heritable across the human life course from adolescence to old age. We investigated the genetic contribution to variation in this important, health- and well-being-related trait ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)Sensitivity to external demands is essential for adaptation to dynamic environments, but comes at the cost of increased risk of adverse outcomes when facing poor environmental conditions. Here, we apply a novel methodology ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Abstract The substantial phenotypic heterogeneity in autism limits our understanding of its genetic etiology. To address this gap, here we investigated genetic differences between autistic individuals ( n max = 12,893) ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Abstract Cortical thickness, surface area and volumes vary with age and cognitive function, and in neurological and psychiatric diseases. Here we report heritability, genetic correlations and genome-wide associations of ...
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(Doctoral thesis / Doktoravhandling, 2009)In this thesis we use genetically informative samples of twins and nuclear families to estimate the relative influence of genetic and environmental risk factors for a varied set of mental disorders. <br> In the first two ...
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(Journal article / Tidsskriftartikkel / SubmittedVersion, 2021)Abstract Genetic liability for schizophrenia is associated with psychopathology in early life. It is not clear if these associations are time dependent during childhood, nor if they are specific across different ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Abstract Identifying mechanisms underlying the intergenerational transmission of risk for attention-deficit/hyperactivity disorder (ADHD) traits can inform interventions and provide insights into the role of parents in ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)Background: Alzheimer’s disease (AD) and depression are debilitating brain disorders that are often comorbid. Shared brain mechanisms have been implicated, yet findings are inconsistent, reflecting the complexity of the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Objective To test the hypothesis that genetic risk for Alzheimer disease (AD) may represent a stable influence on the brain from early in life, rather than being primarily age dependent, we investigated in a lifespan sample ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)Objective We examine the hypothesized overlap of genetic architecture for Alzheimer disease (AD), schizophrenia (SZ), and Parkinson disease (PD) through the use of polygenic risk scores (PRSs) with the occurrence of ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Human wellbeing is influenced by personality traits, in particular neuroticism and extraversion. Little is known about which facets that drive these associations, and the role of genes and environments. Our aim was to ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Background The number of words children produce (expressive vocabulary) and understand (receptive vocabulary) changes rapidly during early development, partially due to genetic factors. Here, we performed a meta–genome-wide ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Background: Attention deficit hyperactivity disorder (ADHD) is a highly heritable neuropsychiatric condition, but it has been difficult to identify genes underlying this disorder. This study aimed to explore genetics of ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental disorders associated with cognitive impairment, which is considered a major determinant of functional outcome. Despite this, the etiology of the cognitive ...
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(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)Background Parkinson’s disease (PD) and schizophrenia (SCZ) are heritable brain disorders that involve dysregulation of the dopaminergic system. Epidemiological studies have reported potential comorbidity between the ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)Objective To investigate the genetic architecture of internalizing symptoms in childhood and adolescence. Method In 22 cohorts, multiple univariate genome-wide association studies (GWASs) were performed using repeated ...