Browsing Farmasøytisk institutt by Title
Now showing items 291-310 of 1937
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(Master thesis / Masteroppgave, 2016)Cancer is one of the leading causes of death worldwide, and anticancer treatments are also known to cause side effects that can affect life quality of the patients severely. Novel drug delivery systems (DDS), e.g., polymeric ...
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(Master thesis / Masteroppgave, 2017)
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Platycodon grandiflorus is a plant widely used in traditional Chinese medicine, of which polysaccharides are reported to be the main components responsible for its bio-functions. In this work, the inulin-type fructan (PGF) ...
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(Master thesis / Hovedoppgave, 2003)Abstract Opportunistic infections due to impaired function of T cells are the main cause of death in HIV infected individuals. It has been shown that T cells from these individuals have elevated levels of cAMP, which ...
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(Doctoral thesis / Doktoravhandling, 2024)In human medicine, there is an ever increasing need to find new disease treatments, due to re-emergence of infectious diseases and multidrug resistance. Historical records consist of valuable data on the use and efficacy ...
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(Doctoral thesis / Doktoravhandling, 2018)The results presented in this thesis describe the investigation of Piscirickettsia salmonis derived membrane vesicles (MVs) as a vaccine candidate against salmonid rickettsial septicemia. MVs are small spherical structures ...
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(Master thesis / Hovedoppgave, 2004)The Escherichia coli SeqA protein, a negative regulator of chromosomal DNA replication, prevents the overinitiation of replication within one cell cycle by binding to hemimethylated GATC sequences in the replication origin, ...
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(Doctoral thesis / Doktoravhandling, 2014)The aim of this thesis was to investigate the chemical and biochemical properties of the Malian medicinal plants Terminalia macroptera and Biophytum umbraculum, with main focus on its phenolic substances. This thesis is a ...
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(Master thesis / Hovedoppgave, 2003)BACKGROUND: Wegener’s granulomatosis (WG) is a severe and potentially life-threatening disease characterized by necrotizing granulomatous vasculitis of small- to medium-sized blood vessels. Chemokines are powerful inflammatory ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)The goal of this study is to examine the extent to which child temperament predicts the adiposity rebound, a steep increase in the body mass index (BMI) between ages 5 and 7 years. If this increase occurs at an earlier ...
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(Doctoral thesis / Doktoravhandling, 2021)‘Can I take this medication now that I am pregnant?’, is a question that many health care professionals have met during consultations with pregnant women. Between 60 and 96% of pregnant women use medications. Analgesics ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)Mucoadhesive drug therapy destined for localized drug treatment is gaining increasing importance in today’s drug development. Chitosan, due to its known biodegradability, bioadhesiveness and excellent safety profile offers ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)Vaginal infections are associated with high recurrence, which is often due to a lack of efficient treatment of complex vaginal infections comprised of several types of pathogens, especially fungi and bacteria. Chitosan, a ...
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(Master thesis / Hovedoppgave, 2007)Background Ciclosporin A (CsA) is an important part of the immunosuppressive regimen in the treatment of renal transplant patients. CsA is typified by a great inter- and intraindividual pharmacokinetic variability, and ...
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(Master thesis / Hovedoppgave, 2007)SAMMENDRAG Bakgrunn: Gruppen med eldre transplanterte pasienter vokser, dette fordi flere og flere eldre transplanteres og fordi transplanterte generelt overlever lenger. Ved økende alder skjer fysiologiske endringer som ...
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Circadisk påvirkning på farmakokinetikken til mykofenolat og mykofenolatglukuronid i nyretransplanterte pasienterRestricted Access (Master thesis / Masteroppgave, 2020)Bakgrunn: Etter en nyretransplantasjon er immunsupprimerende behandling helt nødvendig, og mykofenolatmofetil (MMF) inngår som en del av behandlingen og doseres morgen og kveld. Mykofenolat (MPA) glukuronideres til ...
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Circulating small non-coding RNAs associated with age, sex, smoking, body mass and physical activity (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)Small non-coding RNAs (sncRNA) are regulators of cell functions and circulating sncRNAs from the majority of RNA classes are potential non-invasive biomarkers. Understanding how common traits influence ncRNA expression is ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)Climate change is the biggest challenge facing humanity today. The associated global warming and humidification, increases in the severity and frequency of extreme climate events, extension of the ranges of vector‐borne ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)BACKGROUND. Methodology for estimation of cerebrospinal fluid (CSF) tracer clearance could have wide clinical application in predicting excretion of intrathecal drugs and metabolic solutes from brain metabolism and for ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)Aims Finger‐prick sampling has emerged as an attractive tool for therapeutic drug monitoring and associated diagnostics. We aimed to validate the clinical performance of using two volumetric devices (Capitainer® qDBS and ...