Background The genetic mechanisms for families who meet the clinical criteria for Lynch syndrome (LS) but do not carry pathogenic variants in the mismatch repair (MMR) genes are still undetermined. We aimed ...

Background Although chemo-immunotherapy has led to an improved overall survival for most B-cell lymphoma types, relapsed and refractory disease remains a challenge. The malaria drug artesunate has previously ...

Thanks to the popularity of mobile devices a large number of location-based services (LBS) have emerged. While a large number of privacy-preserving solutions for LBS have been proposed, most of these solutions do not ...

Background In kindreds carrying path_BRCA1/2 variants, some women in these families will develop cancer despite testing negative for the family’s pathogenic variant. These families may have additional ...

Background Pathogenesis of inflammatory diseases can be tracked by studying the causality relationships among the factors contributing to its development. We could, for instance, hypothesize on the connections ...

Background Mammography screening is used to detect breast cancer at an early treatable stage, reducing breast cancer mortality. Traditionally, breast cancer has been seen as a disease with only progressive ...

Background The ballan wrasse (Labrus bergylta) belongs to a large teleost family containing more than 600 species showing several unique evolutionary traits such as lack of stomach and hermaphroditism. ...

The rapidly increasing pervasiveness and integration of computers in human society calls for a broad discipline under which this development can be studied. We argue that to design and use technology one needs to develop ...

Background Increased availability of genome assemblies for non-model organisms has resulted in invaluable biological and genomic insight into numerous vertebrates, including teleosts. Sequencing of the ...

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All software development today is engineered by some form of delivery pipeline regardless of there nature. Within this paradigm of release engineering which may or may not be continuously integrated, there within lies the ...

This thesis asks: “How can health information platforms handle heterogeneity by distributing flexibility among multiple actors?” and uses material from both developing countries and a developed nation to answer this question. ...

One LBE to rule them all and to the deadline bind them

For å forhindre smitte på et sykehus er det viktig med gode hygieneforhold og dermed er det også viktig med gode rutiner på renholdet. For å minke sannsynligheten for smitte er det nødvendig å holde ulike områder så rene ...

The advent of the Internet of Things, sensor and social networks, to mention just a few examples, all contribute towards the solid establishment of the Big Data era. High Performance Computing (HPC) becomes necessary for ...

Background: Recent large-scale undertakings such as ENCODE and Roadmap Epigenomics have generated experimental data mapped to the human reference genome (as genomic tracks) representing a variety of functional elements ...

Today, there exists a wide range of services and applications across several platforms that are prone to attacks. Attackers find new ways to exploit malfunctions and vulnerabilities within these systems every day. There ...

Small, low cost, radar systems have exciting applications in monitoring and imaging for the industrial, healthcare and Internet of Things (IoT) sectors. We here explore, and show the feasibility of, several single bit ...

We report on our experience in ontology-based data access to the Slegge database at Statoil and share the resources employed in this use case: end-user information needs (in natural language), their translations into SPARQL, ...

Threat modelling is a component in security risk analysis, and it is commonly conducted by applying a specific approach for discovering and modelling threats. The three main approaches for threat modelling are asset-centric, ...

To understand a robot's intent and behavior, a robot engineer must analyze data at the input and output, but also at all intermediary steps. This might require looking at a specific subset of the system, or a single data ...

This thesis demonstrates how metaheuristic algorithms can be used to find valid configurations for context-aware software. To represent families of context-aware software, the thesis describes and uses Context-dependent ...

Cloud Computing has seen a tremendous popularity in last several years. A scalable and efficient data center network is essential for a performance capable cloud computing infrastructure. This thesis provides practical ...

This paper addresses the basic implementation and possible competitiveness of an ontology-based ranking method, that for a SPARQL query under construction, generates a ranking of likely extensions, based on a set of past ...

Most Software Product Lines are built from a set of existing products, that is re-engineered into reusable assets following feature location approaches. Traditional feature location approaches target program code, neglecting ...

Purpose: Chemotherapy-induced alterations to gene expression are due to transcriptional reprogramming of tumor cells or subclonal adaptations to treatment. The effect on whole-transcriptome mRNA expression was investigated ...

Cross-domain information exchange is an increasingly important capability for conducting efficient and secure operations, both within coalitions and within single nations. A data guard is a common cross-domain sharing ...

Power consumption of physical and virtual machines is a major challenge for small to larg-scale cloud computing data centers. Hundreds of thousands of physical and virtual machines run in cloud data center which consume ...

Down-scaling of the supply voltage is considered as the most effective means of reducing the power- and energy consumption of integrated circuits (ICs). Reduction in the power- and energy consumption is highly beneficial ...

Intel's Software Guard Extensions (SGX) is a new technology introduced in recent generations of Intel processors. SGX is supposed to be able to create a trusted execution environment for user-space software that is protected ...

Nowadays, the global market offers an enormous variety of external sensors and measuring instruments. In combination with increasingly more powerful mobile devices, it is possible to create new tools which expand their ...

Wave-motion modeling and mathematical optimization have a vast variety of applications in research and industry. Marcus Noack, PhD fellow at Simula Research Laboratory, delved deep into the theoretical and numerical ...

Purpose: Circulating chromogranin B (CgB) levels are increased in situations characterized by systemic and myocardial stress, but whether CgB provides prognostic information in patients with acute respiratory failure (ARF) ...

Objective: Patients with chronic obstructive pulmonary disease (COPD) often have abnormal ECGs. Our aim was to separate the effects on ECG by airway obstruction, emphysema and right ventricular (RV) afterload in patients ...

The final publication is available at IOS Press through http://dx.doi.org/10.3233/COM-170081

Genomic locations are represented as coordinates on a specific genome build version, but the build information is frequently missing when coordinates are provided. We show that this information is essential to correctly ...

Optimisation is a basic principle of nature and has a vast variety of applications in research and industry. There is a plurality of different optimisation procedures which exhibit different strengths and weaknesses in ...

Acoustic waves propagating in anisotropic media are important for various applications. Even though these wave phenomena do not generally occur in nature, they can be used to approximate wave motion in various physical ...

There has been a trend in city development for a little under a decade for cities to become “smart cities”, where recent innovations in technology such as big data processing, IoT, and AI are intended to transform the way ...

The final publication is available at IOS Press.

Datacenters using cloud computing have already gotten a strong foothold as a utility service in ICT environment. The challenge is however, these powerful machines inside the unremarkable looking buildings consume a huge ...

This thesis is an interpretive qualitative research study exploring the use of welfare technology in elderly care. In Norway, health care and social services for elderly people are important parts of the welfare policy. A ...

Analysis of large amounts of data, so called Big Data, is changing the way we think about science and society. One of the most promising rich Big Data sources is mobile phone data, which has the potential to deliver near ...

The book aims to be a resource for those interested in planning and implementing large-scale information infrastructures for novel electronic services in health care. The focus of this book is on the pivotal role of the ...

In this research report we propose a self-organizing media streaming solution that supports multiple interacting participants as well as a large number of observers. This solution is aimed at a number of emerging multimedia ...

Background Breast cancer is a heterogeneous disease at the clinical and molecular level. In this study we integrate classifications extracted from five different molecular levels in order to identify ...

Over the last decade gamification has been emerging as an engaging technology to promote learning. However, the majority of research on game inspired learning has focused on children and adolescents. In this project I am ...

Background The disease and phenotype track was designed to evaluate the relative performance of ontology matching systems that generate mappings between source ontologies. Disease and phenotype ontologies ...

We present a representation of spatial data that supports answering of qualitative queries (involving e.g. containment and overlap), using less time than numerical computations on coordinates, and less space than explicitly ...

The goal of this thesis is to model the resolution of referring expressions (e.g., "the red ball") to visual entities in real world. This task is known as visual reference resolution. In order to address it, two types of ...

Noise. It is around us, everywhere, all the time. It is hard to control, hard to shut out. It affects our health, sometimes even without us noticing it. Noise is one form of pollution, and is causing annoyance and other ...

Electric automobiles (eCars) are considered less harmful to the environment than conventional, fossil-fueled vehicles. Due to economic incentives provided by the Norwegian government, eCars have enjoyed great success in ...

Renewable energy sources, and thus PV are experiencing exponential growth due to most current energy production still relies on fossil fuels, and energy demands are steadily increasing. If the performance of PV could be ...

Electric automobiles (eCars) are considered less harmful to the environment than conventional, fossil-fueled vehicles. Due to economic incentives provided by the Norwegian government, eCars have enjoyed great success in ...

This thesis presents work towards a comprehensive set of methods to extract quantitative shape features and infarct information from cardiac magnetic resonance imaging data to enable classification of a heart disease state ...

The human digestive system can be affected by many types of diseases. For example, three of the six most common cancer types (esophagus, stomach and colorectal) are located in the gastrointestinal tract. Colorectal cancer ...

This thesis is a case study of Uber. The research questions are 1. How do ridesharing platforms evolve from startups into large-scale market disrupters? 2. How can ridesharing platforms augment its user base and capture ...

Systems of healthcare and the field of physical therapy in particular are likely to come under increased stress in the decades to come as populations age faster than their workforces can handle. Much of healthcare is ...

Virtual Reality (VR) for scientific visualization has been researched from the 90s, but there has been little research into the fundamental aspects of VR for scientific visualisation. Questions like "Is VR ready for ...

Digital forretningskompetanse er viktig kompetanse for ledere. Den kan bidra til å øke konkurranseevnen til bedriften gjennom å utnytte mulighetene IT gir. Denne oppgaven undersøker hvordan ledere tar til seg digital ...

In this thesis the focus will be on the speed of light, and how one may reduce its impact on performance. For each remote invocation, there is an associated overhead that corresponds to the latency between the respective ...

A CMOS image sensor with global shutter mechanism, HDR capability and high shutter efficiency has been designed and tested. The image sensor consists of a 128x128 pixel array, readout circuitry and special components for ...

Reliable CCS monitoring is vital in order to confirm that injected CO2 stays in the reservoir as intended, and that any occurring leakage is promptly detected allowing corrective actions to be initiated. Motivations for ...

In model-driven engineering approaches, models are considered firstclass entities. The composition of models is a necessity for modelling software systems. Structural composition of models has been studied thoroughly during ...

This thesis investigates the IT innovation processes in healthcare. The case study research follows a startup company that wants to introduce their app as a tool for the clinical workflow in hospitals. The thesis looks ...

Integration of health information systems (HIS) in developing countries has received a great deal of attention over the last ten years. Most academic writing on this subject has been concerned with the integration of health ...

This thesis examines how the hadoop-stack can be used to create a database for observational weather data. Hbase was used as a means to store data on HDFS while maintaining relatively short response time for queries. In ...

Dette studiet analyserer forholdet mellom pengekompensasjon og motivasjon i den norske virksomheten av et IT- infrastrukturselskap.. Økonomiske og psykologiske teorier spår at design og implementering av prestasjonsmåling ...

Refactoring is an essential operation in software engineering, with the purpose of improving the structural qualities of software. An emerging trend in software engineering is the use of model-driven approaches in which ...

Previously, we have worked on verification of railway regulations against CAD designs, and integrated a verification engine into the tool chain of railway engineers. This tool was used successfully in a pilot project at ...

The concrete problem this paper addresses is the following: Given a set of objects with a spatial interpretation and a set of qualitative relations, construct a bintree representation that returns the same answers to queries ...

Online grocery shopping is an increasing trend in many countries. Several studies have been done to investigate different aspects of online grocery shopping. Researchers have found that the likelihood that there will be ...

Many health professionals in developing countries lack the proper competence for the work they are doing. Tooltips have previously proven to be effective, and may assist such health professionals in their daily routines ...

Fast and efficient communication is crucial for workers that are required to collaborate. Instant messaging has been found to be more efficient than email and other asynchronous messaging systems when used for asking quick ...