Background This trial evaluates interventions that utilize data entered at point-of-care in the Palestinian maternal and child eRegistry to generate Quality Improvement Dashboards (QID) for healthcare ...

Colonoscopy is considered the gold standard for detection of colorectal cancer and its precursors. Existing examination methods are, however, hampered by high overall miss-rate, and many abnormalities are left undetected. ...

Algorithmic decision-making is rapidly evolving as a source of data-driven competitive advantage with important implications for analytical practices in multiple settings. Despite the ambitions for algorithmic and intelligent ...

Electroencephalography (EEG) and magnetoencephalography (MEG) are among the most important techniques for non-invasively studying cognition and disease in the human brain. These signals are known to originate from cortical ...

Background Advances in whole genome sequencing strategies have provided the opportunity for genomic and comparative genomic analysis of a vast variety of organisms. The analysis results are highly dependent on the quality ...

Background There is a need for validated clinical risk scores to identify patients at risk of severe disease and to guide decision-making during the covid-19 pandemic. The National Early Warning Score 2 (NEWS2) is widely ...

Surface electromyography (sEMG) provides an intuitive and non-invasive interface from which to control machines. However, preserving the myoelectric control system’s performance over multiple days is challenging, due to ...

THIS STUDY REPORTS ON AN EXPERIMENT THAT tested whether drummers systematically manipulated not only onset but also duration and/or intensity of strokes in order to achieve different timing styles. Twenty-two professional ...

Wireless Sensor Networks (WSNs) typically include thousands of resource-constrained sensors to monitor their surroundings, collect data, and transfer it to remote servers for further processing. Although WSNs are considered ...

This paper analyzes work activity in the home, e.g., cleaning, performed by two actors, a human and a robot. Nowadays, there are attempts to automate this activity through the use of robots. However, the activity of cleaning, ...

Chatbots represent new opportunities for low-threshold preventive mental health support to youths. To provide needed knowledge regarding how to design chatbots for this purpose, we present an exploratory design study where ...

The aim of this study was the analysis of the risk associated with direct oral anticoagulants (DOACs) in patients undergoing non-elective operations on the proximal aorta due to aortic disease.Methods and resultsData from ...

Background The human microbiota contributes to health and well-being. Antimicrobials (AM) have an immediate effect on microbial diversity and composition in the gut, but next to nothing is known about their long-term ...

Background The dementia subtype idiopathic normal pressure hydrocephalus (iNPH) has unknown etiology, but one characteristic is elevated intracranial pressure (ICP) wave amplitudes in those individuals who respond with ...

Autoantibodies to transglutaminase 2 (TG2) are hallmarks of celiac disease. To address B cell tolerance and autoantibody formation to TG2, we generated immunoglobulin knock-in (Ig KI) mice that express a prototypical celiac ...

The study focuses on fragmented information awareness as a result of the cross-use of Digital Learning Environments (DLEs), rather than focusing on the use of individual Learning Management Systems (LMSs). This study goes ...

Spectral Doppler measurements are an important part of the standard echocardiographic examination. These measurements give insight into myocardial motion and blood flow providing clinicians with parameters for diagnostic ...

Given the relevance of coordination in the field of global software engineering, this work was carried out to further understand coordination mechanisms. Specifically, we investigated meetings and the collaboration tool ...

Background: In precision cancer medicine, the challenge is to prioritize DNA driver events, account for resistance markers, and procure sufficient information for treatment that maintains patient safety. The MetAction ...

Somatic copy number alterations are a frequent sign of genome instability in cancer. A precise characterization of the genome architecture would reveal underlying instability mechanisms and provide an instrument for outcome ...

Tabular data to Knowledge Graph matching is the process of assigning semantic tags from knowledge graphs (e.g., Wikidata or DBpedia) to the elements of a table. This task is a challenging problem for various reasons, ...

Background A high intake of linoleic acid (LA), the major dietary polyunsaturated fatty acid (PUFA), has previously been associated with reduced cardiovascular (CV) morbidity and mortality in observational studies. ...

Antiangiogenic drugs are potentially a useful supplement to neoadjuvant chemotherapy for a subgroup of patients with human epidermal growth factor receptor 2 (HER2) negative breast cancer, but reliable biomarkers for ...

Table annotation is a key task to improve querying the Web and support the Knowledge Graph population from legacy sources (tables). Last year, the SemTab challenge was introduced to unify different efforts to evaluate table ...

In the last 30 years, the contrast-to-noise ratio (CNR) has been used to estimate the contrast and lesion detectability in ultrasound images. Recent studies have shown that the CNR cannot be used with modern beamformers, ...

We argue that there is a link between implicit computational complexity theory and the theory of reversible computation. We show that the complexity classes ETIME and P can be captured by inherently reversible programming ...

Defining a representative locality is an urgent challenge in perturbation-based explanation methods, which influences the fidelity and soundness of explanations. We address this issue by proposing a robust and intuitive ...

The cholesterol-sensing nuclear receptor liver X receptor (LXR) and the glucose-sensing transcription factor carbohydrate responsive element-binding protein (ChREBP) are central players in regulating glucose and lipid ...

Background Improved markers of prognosis are needed to stratify patients with early-stage colorectal cancer to refine selection of adjuvant therapy. The aim of the present study was to develop a biomarker of patient ...

Spatial resolution is defined as a system's ability to separate targets using some kind of criterion, such as the Rayleigh criterion. However, in practice, lateral resolution is often evaluated by measuring the Full Width ...

Network APIs are moving towards protocol agility, where applications express their needs but not a static protocol binding, and it is up to the layer below the API to choose a suitable protocol. The IETF Transport Services ...

Ever since the agile manifesto was created in 2001, the research community has devoted attention to autonomous teams. This article first examines publications on autonomous agile teams to illustrate how the research has ...

We propose a method for jointly estimating intrinsic calibration and internal clock synchronisation for a pantilt- zoom (PTZ) camera using only data that can be acquired in the field during normal operation. Results show ...

Data governance is concerned with leveraging the potential value of data in data infrastructures. In IS research, data governance has developed as a management perspective, implying a narrow view of who makes decisions ...

Abstract Summary B- and T-cell receptor repertoires of the adaptive immune system have become a key target for diagnostics and therapeutics research. Consequently, there is a rapidly growing ...

DNA methylation (5mC) and hydroxymethylation (5hmC) are chemical modifications of cytosine bases which play a crucial role in epigenetic gene regulation. However, cost, data complexity and unavailability of comprehensive ...

The quality of a dataset used for evaluating data linking methods, techniques, and tools depends on the availability of a set of mappings, called reference alignment, that is known to be correct. In particular, it is crucial ...

Current practice of assessing mood episodes in affective disorders largely depends on subjective observations combined with semi-structured clinical rating scales. Motor activity is an objective observation of the inner ...

Most Internet hosts today support multiple access technologies and network interfaces. Multipath transport protocols, like MPTCP, are being deployed (e.g., in smartphones), allowing transparent simultaneous use of multiple ...

Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale1,2,3. Here we report the integrative analysis of 2,658 ...

Artificial intelligence is currently a hot topic in medicine. However, medical data is often sparse and hard to obtain due to legal restrictions and lack of medical personnel for the cumbersome and tedious process to ...

Many scholars have pointed to Austrian subjectivism as an appropriate framework for understanding and studying entrepreneurship. Yet very few empirical studies in the field of entrepreneurship have applied a subjectivist ...

Uncertainty and the pursuit of new ventures are intricately linked. Digital technologies open up new ways for uncertainty handling in the pursuit of novelty. In this paper, we develop a process model that traces the dynamics ...

The object sizes in images are diverse, therefore, capturing multiple scale context information is essential for semantic segmentation. Existing context aggregation methods such as pyramid pooling module (PPM) and atrous ...

Laparoscopic videos can be affected by different distortions which may impact the performance of surgery and introduce surgical errors. In this work, we propose a framework for automatically detecting and identifying such ...

Meticulous preoperative planning is an important part of any surgery to achieve high levels of precision and avoid complications. Conventional medical 2D images and their corresponding three-dimensional (3D) reconstructions ...

Human phosphoglucomutase 1 (PGM1) is an evolutionary conserved enzyme that belongs to the ubiquitous and ancient α-d-phosphohexomutases, a large enzyme superfamily with members in all three domains of life. PGM1 catalyzes ...

How do configurations of humans and algorithms evolve as firms adopt artificial intelligence (AI) capabilities, and what are the implications for work and organization? We explored these questions through a two-year long ...

The growth of digital ecosystems such as Google, Apple and Uber has led to radical changes in economic activity, work and consumption. It has also challenged established economic, social and organization theory, which has ...

We used sleep monitoring data from a study that investigated the prevalence, characteristics, risk factors and type of sleep apnea (SA) in 579 patients with paroxysmal atrial fibrillation. Most patients were screened for ...

Abstract In B lymphocytes, the uracil N-glycosylase (UNG) excises genomic uracils made by activation-induced deaminase (AID), thus underpinning antibody gene diversification and oncogenic chromosomal translocations, ...

Experimental studies in neuroscience are producing data at a rapidly increasing rate, providing exciting opportunities and formidable challenges to existing theoretical and modeling approaches. To turn massive datasets ...

Abstract Agile transformation implies that organizations apply agile methods also outside of software development units. One particular way of doing such transformations is to create cross-functional software development ...

Automatic human activity detection, mainly transport-wise, is very relevant for architects and urban planners (among many others) when designing cities, roads, public transportation systems, etc. Such detection allows to ...

BAKGRUNN Norske retningslinjer for primærforebygging av hjerte- og karsykdom anbefaler bruk av risikoskårmodellen NORRISK-2, med noen tillegg. Vi ønsket å undersøke om NORRISK-2 kunne predikere hjerte- og karsykdom hos ...

Program evolution may reveal bad design decisions, misunderstandings, erroneous code, or erroneous specifications, because problems made early in the design of a system may not be discovered until much later in the life-time ...

Abstract Measurements of the left ventricular (LV) pressure trace are rarely performed despite high clinical interest. We estimated the LV pressure trace for an individual heart by scaling the isovolumic, ejection and ...

Multi-function swarms are swarms that solve multiple tasks at once. For example, a quadcopter swarm could be tasked with exploring an area of interest while simultaneously functioning as ad-hoc relays. With this type of ...

Current ultrasonic Local Positioning Systems (LPS) based on an infrastructure of beacons can provide centimeter-level accuracy employing the spread spectrum technique, which also adds robustness against noise. However, the ...

This paper presents an overview of the ImageCLEF 2020 lab that was organized as part of the Conference and Labs of the Evaluation Forum - CLEF Labs 2020. ImageCLEF is an ongoing evaluation initiative (first run in 2003) ...

Background Graph-based reference genomes have become popular as they allow read mapping and follow-up analyses in settings where the exact haplotypes underlying a high-throughput sequencing experiment are ...

Sixty years have passed since neurosurgeon Nils Lundberg presented his thesis about intracranial pressure (ICP) monitoring, which represents a milestone for its clinical introduction. Monitoring of ICP has since become a ...

The structure and performance of neural networks are intimately connected, and by use of evolutionary algorithms, neural network structures optimally adapted to a given task can be explored. Guiding such neuroevolution ...

Internet of Things (IoT) is a new technology that is driving the connection of billions of devices around the world. Because these devices are often resource‐constrained and very heterogeneous, this presents unique challenges. ...

Background Targeted client communication (TCC) using text messages can inform, motivate and remind pregnant and postpartum women of timely utilization of care. The mixed results of the effectiveness of TCC interventions ...

Dynamic resource provisioning is an important driver for pay-on-demand cloud computing. Virtualized resources open for resource awareness, such that applications may use resource management strategies to modify their ...

A typical approach to reduce speckle in coherent imaging systems, is to average same-target images with different speckle realizations. We study settings where such realizations come from applying different transducer-array ...

In March 2020 the number of confirmed COVID-19 cases in Norway increased rapidly, and the efforts to trace contacts of positive cases were under severe pressure. Contact tracing in Norway is the responsibility of the ...

Fascicle (fiber bundle) orientation and length are useful parameters to infer the force potential of skeletal muscles. Ultrasound imaging is commonly used to determine fascicle characteristics. In most of the literature, ...

360∘ panorama video displayed through Virtual Reality (VR) glasses or large screens offers immersive user experiences, but as such technology becomes commonplace, the need for efficient streaming methods of such high-bitrate ...

In their seminal review article on board of directors, Johnson, Daily, and Ellstrand (1996) distinguished between the control, service, and resource dependence tasks of the board and called for a stronger focus on board ...

Exploring the effects of a chemical compound on a species takes a considerable experimental effort. Appropriate methods for estimating and suggesting new effects can dramatically reduce the work needed to be done by a ...

In this paper, we present a preliminary study to compute embeddings for OWL 2 ontologies by projecting the ontology axioms into a graph and performing (random) walks over the ontology graph to create a corpus of sentences. ...

Data preprocessing is a crucial step in data analysis. A substantial amount of time is spent on data transformation tasks such as data formatting, modification, extraction, and enrichment, typically making it more convenient ...

Left ventricular (LV) dilatation is a key step in transition to heart failure (HF) in response to pressure overload. Cardiac extracellular matrix (ECM) contains fibrillar collagens and proteoglycans, important for maintaining ...

DiffServ was designed to implement service provider quality of service (QoS) policies, where routers change and react upon the DiffServ Code Point (DSCP) in the IP header. However, nowadays, applications are beginning to ...

The brain is the most complex of human organs, and the pathophysiology underlying abnormal brain function in psychiatric disorders is largely unknown. Despite the rapid development of diagnostic tools and treatments in ...

A microfluidic laminar flow cell (LFC) forms an indispensable component in single-molecule experiments, enabling different substances to be delivered directly to the point under observation and thereby tightly controlling ...

XTRA (XFSM for Transport) aims at providing a first attempt towards a “code-once-port-everywhere” platform-agnostic programming abstraction tailored to the deployment of transport layer functions. XTRA's programming ...

Direct integration of Carbon Nanotubes (CNTs) in CMOS is important for commercially manufacturing low-cost CNT-based sensors. In such compact sensors, CNTs would act as sensing element, and CMOS circuits would process ...

Software beamforming allows more flexible and complex algorithms, often referred to as adaptive beamforming techniques, that are blurring the boundaries between beamforming and image processing. Many adaptive beamforming ...

To meet the demands of communication‐intensive workloads in the cloud, virtual machines (VMs) should utilize low overhead network communication paradigms. In general, such paradigms enable VMs to directly communicate with ...

Expertise in digital technologies is necessary, but rarely sufficient to generate digital innovation. The purpose of this paper is to explore how specialists rooted in digital and analog knowledge domains engage in ...

Current state-of-the-art models for sentiment analysis make use of word order either explicitly by pre-training on a language modeling objective or implicitly by using recurrent neural networks (Rnns) or convolutional ...

This paper presents a duty cycle-based, dual-mode simultaneous wireless information and power transceiver (SWIPT) for Internet of Things (IoT) devices in which a sensor node monitors the received power and adaptively ...

We give the first non-interleaving early operational semantics for the pi-calculus which generalises the standard interleaving semantics and unfolds to the stable model of prime event structures. Our starting point is the ...

Peritoneal malignant mesothelioma is a rare disease with a generally poor prognosis and poor response to chemotherapy. To improve survival there is a need for increased molecular understanding of the disease, including ...

Is digital management something else than general management? In this paper we contend that it is, both theoretically and in practice. To develop our argument, we suggest a framework for understanding the particular aspects ...

Heterogeneous mechanical dyskinesis has been implicated in many arrhythmogenic phenotypes. Strain-dependent perturbations to cardiomyocyte electrophysiology may contribute to this arrhythmogenesis through processes referred ...

Graph-based representations are considered to be the future for reference genomes, as they allow integrated representation of the steadily increasing data on individual variation. Currently available tools allow de novo ...

Concurrent programs often make use of futures, handles to the results of asynchronous operations. Futures provide means to communicate not yet computed results, and simplify the implementation of operations that synchronise ...

This paper presents a morphological analysis of fibrotic scarring in non-ischemic dilated cardiomyopathy, and its relationship to electrical instabilities which underlie reentrant arrhythmias. Two dimensional electrophysiological ...

Underwater acoustic communication or localization systems can be affected by the Doppler effect when the receiver or emitter is in motion. In those cases, the use of an a appropiate encoding/modulating scheme play a pivotal ...

We have surveyed 191 prospectively sampled familial cancer patients with no previously detected pathogenic variant in the BRCA1/2, PTEN, TP53 or DNA mismatch repair genes. In all, 138 breast cancer (BC) cases, 34 colorectal ...

User validation is one of the challenges facing the ontology alignment community, as there are limits to the quality of the alignments produced by automated alignment algorithms. In this paper, we present a broad study on ...

Modern workloads often exceed the processing and I/O capabilities provided by resource virtualization, requiring direct access to the physical hardware in order to reduce latency and computing overhead. For computers ...

Ontology-based knowledge bases (KBs) like DBpedia are very valuable resources, but their usefulness and usability are limited by various quality issues. One such issue is the use of string literals instead of semantically ...

3D Transesophageal Echocardiography is an excellent tool for evaluating the mitral valve and is also well suited for guiding cardiac interventions. We introduce a fully automatic method for mitral annulus segmentation in ...