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eRegCom—Quality Improvement Dashboard for healthcare providers and Targeted Client Communication to pregnant women using data from an electronic health registry to improve attendance and quality of antenatal care: study protocol for a multi-arm cluster randomized trial 
Mørkrid, Kjersti; Bogale, Binyam; Abbas, Eatimad; Abu Khader, Khadija; Abu Ward, Itimad; Attalh, Amjad; Awwad, Tamara; Baniode, Mohammad; Frost, Kimberly Suzanne; Frost, Michael J; Ghanem, Buthaina; Hijaz, Taghreed; Isbeih, Mervett; Issawi, Sally; Nazzal, Zaher A S; O’Donnell, Brian; Qaddomi, Sharif E; Rabah, Yousef; Venkateswaran, Mahima; Frøen, J. F (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background This trial evaluates interventions that utilize data entered at point-of-care in the Palestinian maternal and child eRegistry to generate Quality Improvement Dashboards (QID) for healthcare ...
A Comprehensive Study on Colorectal Polyp Segmentation with ResUNet++, Conditional Random Field and Test-Time Augmentation 
Jha, Debesh; Smedsrud, Pia; Johansen, Dag; de Lange, Thomas; Johansen, Håvard D.; Halvorsen, Pål; Riegler, Michael Alexander (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Colonoscopy is considered the gold standard for detection of colorectal cancer and its precursors. Existing examination methods are, however, hampered by high overall miss-rate, and many abnormalities are left undetected. ...
Assembling Algorithmic Decision-Making under Uncertainty: The Case of 'Edge Cases' in an Open Data Environment 
Grønsund, Tor Rolfsen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Algorithmic decision-making is rapidly evolving as a source of data-driven competitive advantage with important implications for analytical practices in multiple settings. Despite the ambitions for algorithmic and intelligent ...
Biophysically detailed forward modeling of the neural origin of EEG and MEG signals 
Næss, Solveig; Halnes, Geir; Hagen, Espen; Hagler, Donald J.; Dale, Anders M.; Einevoll, Gaute; Ness, Torbjørn Vefferstad (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Electroencephalography (EEG) and magnetoencephalography (MEG) are among the most important techniques for non-invasively studying cognition and disease in the human brain. These signals are known to originate from cortical ...
NucBreak: location of structural errors in a genome assembly by using paired-end Illumina reads 
Khelik, Ksenia; Sandve, Geir K; Nederbragt, Alexander J; Rognes, Torbjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background Advances in whole genome sequencing strategies have provided the opportunity for genomic and comparative genomic analysis of a vast variety of organisms. The analysis results are highly dependent on the quality ...
National Early Warning Score 2 (NEWS2) on admission predicts severe disease and in-hospital mortality from Covid-19 – a prospective cohort study 
Myrstad, Marius; Ihle-Hansen, Håkon; Tveita, Anders A; Andersen, Elizabeth L; Nygård, Ståle; Tveit, Arnljot; Berge, Trygve (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background There is a need for validated clinical risk scores to identify patients at risk of severe disease and to guide decision-making during the covid-19 pandemic. The National Early Warning Score 2 (NEWS2) is widely ...
Unsupervised Domain Adversarial Self-Calibration for Electromyography-Based Gesture Recognition 
Côté-Allard, Ulysse; Gagnon-Turcotte, Gabriel; Phinyomark, Angkoon; Glette, Kyrre; Scheme, Erik; Laviolette, Francois; Gosselin, Benoit (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Surface electromyography (sEMG) provides an intuitive and non-invasive interface from which to control machines. However, preserving the myoelectric control system’s performance over multiple days is challenging, due to ...
Timing Is Everything... Or Is It? Effects of Instructed Timing Style, Reference and Pattern on Drum Kit Sound in Groove-Based Performance 
Câmara, Guilherme Schmidt; Nymoen, Kristian; Lartillot, Olivier; Danielsen, Anne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
THIS STUDY REPORTS ON AN EXPERIMENT THAT tested whether drummers systematically manipulated not only onset but also duration and/or intensity of strokes in order to achieve different timing styles. Twenty-two professional ...
Clustering objectives in wireless sensor networks: A survey and research direction analysis 
Shahraki, Amin; Taherkordi, Amirhosein; Haugen, Øystein; Eliassen, Frank (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Wireless Sensor Networks (WSNs) typically include thousands of resource-constrained sensors to monitor their surroundings, collect data, and transfer it to remote servers for further processing. Although WSNs are considered ...
Computable Irrational Numbers with Representations of Surprising Complexity 
Georgiev, Ivan; Kristiansen, Lars; Stephan, Frank (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
A Framework on Division of Work Tasks between Humans and Robots in the Home 
Saplacan, Diana; Herstad, Jo; Tørresen, Jim; Pajalic, Zada (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
This paper analyzes work activity in the home, e.g., cleaning, performed by two actors, a human and a robot. Nowadays, there are attempts to automate this activity through the use of robots. However, the activity of cleaning, ...
Hi, can I help? Exploring how to design a mental health chatbot for youths 
Høiland, Camilla Gudmundsen; Følstad, Asbjørn; Karahasanovic, Amela (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Chatbots represent new opportunities for low-threshold preventive mental health support to youths. To provide needed knowledge regarding how to design chatbots for this purpose, we present an exploratory design study where ...
Operative survival in patients with acute aortic disease in the era of newer oral anticoagulants 
BJØRNSTAD, JOHANNES; Khan, Adil Mahboob; Røed-Undlien, Henriette; Bendz, Bjørn; Nygård, Ståle; Hoel, Tom N; Lingaas, Per Snorre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The aim of this study was the analysis of the risk associated with direct oral anticoagulants (DOACs) in patients undergoing non-elective operations on the proximal aorta due to aortic disease.Methods and resultsData from ...
Antimicrobial drug use in the first decade of life influences saliva microbiota diversity and composition 
Raju, Sajan C; Viljakainen, Heli; Figueiredo, Rejane A O; Neuvonen, Pertti J; Eriksson, Johan G; Weiderpass, Elisabete; Rounge, Trine B (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background The human microbiota contributes to health and well-being. Antimicrobials (AM) have an immediate effect on microbial diversity and composition in the gut, but next to nothing is known about their long-term ...
Mechanisms behind altered pulsatile intracranial pressure in idiopathic normal pressure hydrocephalus: role of vascular pulsatility and systemic hemodynamic variables 
Evensen, Karen Brastad; Eide, Per Kristian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background The dementia subtype idiopathic normal pressure hydrocephalus (iNPH) has unknown etiology, but one characteristic is elevated intracranial pressure (ICP) wave amplitudes in those individuals who respond with ...
B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2. 
du Pré, Fleur; Blazevski, Jana; Dewan, Alisa Elinsdatter; Stamnæs, Jorunn; Kanduri, Chakravarthi; Sandve, Geir Kjetil; Johannesen, Marie Kongshaug; Lindstad, Christian Borgen; Hnida, Kathrin; Fugger, Lars; Melino, Gerry; Qiao, Shuo-Wang; Sollid, Ludvig Magne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Autoantibodies to transglutaminase 2 (TG2) are hallmarks of celiac disease. To address B cell tolerance and autoantibody formation to TG2, we generated immunoglobulin knock-in (Ig KI) mice that express a prototypical celiac ...
Use of Digital Learning Environments: A Study about Fragmented Information Awareness 
Saplacan, Diana; Herstad, Jo; Pajalic, Zada (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The study focuses on fragmented information awareness as a result of the cross-use of Digital Learning Environments (DLEs), rather than focusing on the use of individual Learning Management Systems (LMSs). This study goes ...
User-Intended Doppler Measurement Type Prediction Combining CNNs With Smart Post-Processing 
Gilbert, Andrew David; Holden, Marit; Eikvil, Line; Rakhmail, Mariia; Babic, Aleksandar; Aase, Svein Arne; Samset, Eigil; Mcleod, Kristin (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Spectral Doppler measurements are an important part of the standard echocardiographic examination. These measurements give insight into myocardial motion and blood flow providing clinicians with parameters for diagnostic ...
Understanding coordination in global software engineering: A mixed-methods study on the use of meetings and Slack 
Stray, Viktoria; Moe, Nils Brede (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Given the relevance of coordination in the field of global software engineering, this work was carried out to further understand coordination mechanisms. Specifically, we investigated meetings and the collaboration tool ...
Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer?the MetAction study 
Ree, Anne Hansen; Nygaard, Vigdis; Pedersen, Kjetil Boye; Heinrich, Daniel; Dueland, Svein; Bergheim, Inger Riise; Johansen, Christin; Beiske, Klaus; Negård, Anne; Lund-Iversen, Marius; Nygaard, Vegard; Hovig, Eivind; Nakken, Sigve; Nasser, Salah; Julsrud, Lars; Reisse, Claudius; Ruud, Espen Asak; Kristensen, Vessela N.; Flørenes, Vivi Ann; Geitvik, Gry; Lingjærde, Ole Christian; Børresen-Dale, Anne-Lise; Russnes, Hege Elisabeth Giercksky; Mælandsmo, Gunhild Mari; Flatmark, Kjersti (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background: In precision cancer medicine, the challenge is to prioritize DNA driver events, account for resistance markers, and procure sufficient information for treatment that maintains patient safety. The MetAction ...
DNA copy number motifs are strong and independent predictors of survival in breast cancer 
Pladsen, Arne Valebjørg; Nilsen, Gro; Rueda, Oscar M.; Aure, Miriam Ragle; Borgan, Ørnulf; Liestøl, Knut; Vitelli, Valeria; Frigessi Di Rattalma, Arnoldo; Langerød, Anita; Mathelier, Anthony; Engebråten, Olav; Kristensen, Vessela N.; Wedge, David C.; Van Loo, Peter; Caldas, Carlos; Børresen-Dale, Anne-Lise; Russnes, Hege Elisabeth Giercksky; Lingjærde, Ole Christian (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Somatic copy number alterations are a frequent sign of genome instability in cancer. A precise characterization of the genome architecture would reveal underlying instability mechanisms and provide an instrument for outcome ...
SemTab 2019: Resources to Benchmark Tabular Data to Knowledge Graph Matching Systems 
Jimenez-Ruiz, Ernesto; Hassanzadeh, Oktie; Efthymiou, Vasilis; Chen, Jiaoyan; Srinivas, Kavitha (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Tabular data to Knowledge Graph matching is the process of assigning semantic tags from knowledge graphs (e.g., Wikidata or DBpedia) to the elements of a table. This task is a challenging problem for various reasons, ...
Plasma linoleic acid levels and cardiovascular risk factors: results from the Norwegian ACE 1950 Study 
Chandra, Anupam; Røsjø, Helge; Svensson, My Hanna Sofia; Vigen, Thea; Ihle-Hansen, Håkon; Orstad, Eivind Bjørkan; Rønning, Ole M.; Lyngbakken, Magnus; Nygård, Ståle; Berge, Trygve; Schmidt, Erik Berg; Omland, Torbjørn; Tveit, Arnljot; Eide, Ivar Anders (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Background A high intake of linoleic acid (LA), the major dietary polyunsaturated fatty acid (PUFA), has previously been associated with reduced cardiovascular (CV) morbidity and mortality in observational studies. ...
Immune phenotype of tumor microenvironment predicts response to bevacizumab in neoadjuvant treatment of ER-positive breast cancer 
Gythfeldt, Hedda von der Lippe; Lien, Tonje Gulbrandsen; Tekpli, Xavier; Silwal-Pandit, Laxmi; Borgen, Elin; Garred, Øystein; Skjerven, Helle; Schlichting, Ellen; Lundgren, Steinar; Wist, Erik; Naume, Bjørn; Kristensen, Vessela N.; Børresen-Dale, Anne-Lise; Lingjærde, Ole Christian; Engebråten, Olav (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Antiangiogenic drugs are potentially a useful supplement to neoadjuvant chemotherapy for a subgroup of patients with human epidermal growth factor receptor 2 (HER2) negative breast cancer, but reliable biomarkers for ...
Tough Tables: Carefully Evaluating Entity Linking for Tabular Data 
Cutrona, Vincenzo; Bianchi, Federico; Jimenez-Ruiz, Ernesto; Palmonari, Matteo (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Table annotation is a key task to improve querying the Web and support the Knowledge Graph population from legacy sources (tables). Last year, the SemTab challenge was introduced to unify different efforts to evaluate table ...
The Generalized Contrast-to-Noise Ratio: A Formal Definition for Lesion Detectability 
Molares, Alfonso Rodrígues; Rindal, Ole Marius Hoel; D´Hooge, Jan; Måsøy, Svein-Erik; Austeng, Andreas; Bell, Muyinatu A. Lediju; Torp, Hans (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
In the last 30 years, the contrast-to-noise ratio (CNR) has been used to estimate the contrast and lesion detectability in ultrasound images. Recent studies have shown that the CNR cannot be used with modern beamformers, ...
Reversible programming languages capturing complexity classes. 
Kristiansen, Lars (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
We argue that there is a link between implicit computational complexity theory and the theory of reversible computation. We show that the complexity classes ETIME and P can be captured by inherently reversible programming ...
EXPLAN: Explaining Black-box Classifiers using Adaptive Neighborhood Generation 
Rasouli, Peyman; Yu, Ingrid Chieh (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Defining a representative locality is an urgent challenge in perturbation-based explanation methods, which influences the fidelity and soundness of explanations. We address this issue by proposing a robust and intuitive ...
LXRα Regulates ChREBPα Transactivity in a Target Gene-Specific Manner through an Agonist-Modulated LBD-LID Interaction 
Fan, Qiong; Nørgaard, Rikke Christine; Grytten, Ivar; Ness, Cecilie Maria; Lucas, Christin; Vekterud, Kristin; Soedling, Helen; Matthews, Jason; Lemma, Roza Berhanu; Gabrielsen, Odd Stokke; Bindesbøll, Christian; Ulven, Stine Marie; Nebb, Hilde Irene; Grønning-Wang, Line Mariann; Sæther, Thomas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The cholesterol-sensing nuclear receptor liver X receptor (LXR) and the glucose-sensing transcription factor carbohydrate responsive element-binding protein (ChREBP) are central players in regulating glucose and lipid ...
Deep learning for prediction of colorectal cancer outcome: a discovery and validation study 
Skrede, Ole-Johan; De Raedt, Sepp; Kleppe, Andreas; Hveem, Tarjei Sveinsgjerd; Liestøl, Knut; Maddison, John; Askautrud, Hanne Arenberg; Pradhan, Manohar; Nesheim, John Arne; Albregtsen, Fritz; Farstad, Inger Nina; Domingo, Enric; Church, David N.; Nesbakken, Arild; Shepherd, Neil A; Tomlinson, Ian; Kerr, Rachel; Novelli, Marco; Kerr, David; Danielsen, Håvard Emil (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Background Improved markers of prognosis are needed to stratify patients with early-stage colorectal cancer to refine selection of adjuvant therapy. The aim of the present study was to develop a biomarker of patient ...
Resolution Measured as Separability Compared to Full Width Half Maximum for Adaptive Beamformers 
Rindal, Ole Marius Hoel; Rodriguez-Molares, Alfonso; Austeng, Andreas (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Spatial resolution is defined as a system's ability to separate targets using some kind of criterion, such as the Rayleigh criterion. However, in practice, lateral resolution is often evaluated by measuring the Full Width ...
On the Usability of Transport Protocols other than TCP: A Home Gateway and Internet Path Traversal Study 
Barik, Runa; Welzl, Michael; Fairhurst, Gorry; Elmokashfi, Ahmed; Dreibholz, Thomas; Gjessing, Stein (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Network APIs are moving towards protocol agility, where applications express their needs but not a static protocol binding, and it is up to the layer below the API to choose a suitable protocol. The IETF Transport Services ...
A Decade of Research on Autonomous Agile Teams: A Summary of the Third International Workshop 
Moe, Nils Brede; Stray, Viktoria (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Ever since the agile manifesto was created in 2001, the research community has devoted attention to autonomous teams. This article first examines publications on autonomous agile teams to illustrate how the research has ...
In-operation calibration of clock-bias and intrinsic parameters for pan-tilt-zoom cameras based on keypoint tracking 
Larsen, Martin Vonheim; Haavardsholm, Trym Vegard; Mathiassen, Kim (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
We propose a method for jointly estimating intrinsic calibration and internal clock synchronisation for a pantilt- zoom (PTZ) camera using only data that can be acquired in the field during normal operation. Results show ...
Data Curation as Governance Practice 
Parmiggiani, Elena; Grisot, Miria (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Data governance is concerned with leveraging the potential value of data in data infrastructures. In IS research, data governance has developed as a management perspective, implying a narrow view of who makes decisions ...
immuneSIM: tunable multi-feature simulation of B- and T-cell receptor repertoires for immunoinformatics benchmarking 
Weber, Cédric R.; Akbar, Rahmad; Yermanos, Alexander; Pavlovic, Milena; Snapkov, Igor; Sandve, Geir Kjetil; Reddy, Sai T.; Greiff, Victor (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract Summary B- and T-cell receptor repertoires of the adaptive immune system have become a key target for diagnostics and therapeutics research. Consequently, there is a rapidly growing ...
HMST-Seq-Analyzer: A new python tool for differential methylation and hydroxymethylation analysis in various DNA methylation sequencing data 
Farooq, Amna; Grønmyr, Sindre; Omer, Ali Avan; Rognes, Torbjørn; Scheffler, Katja; Bjørås, Magnar; Wang, Junbai (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
DNA methylation (5mC) and hydroxymethylation (5hmC) are chemical modifications of cytosine bases which play a crucial role in epigenetic gene regulation. However, cost, data complexity and unavailability of comprehensive ...
Crowd-assessing quality in uncertain data linking datasets 
Faria, Daniel; Ferrara, Alfio; Jimenez-Ruiz, Ernesto; Montanelli, Stefano; Pesquita, Catia (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
The quality of a dataset used for evaluating data linking methods, techniques, and tools depends on the availability of a set of mappings, called reference alignment, that is known to be correct. In particular, it is crucial ...
Applying machine learning in motor activity time series of depressed bipolar and unipolar patients compared to healthy controls 
Jakobsen, Petter; Garcia-Ceja, Enrique; Riegler, Michael; Stabell, Lena Antonsen; Nordgreen, Tine; Tørresen, Jim; Fasmer, Ole Bernt; Ødegaard, Ketil Joachim (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Current practice of assessing mood episodes in affective disorders largely depends on subjective observations combined with semi-structured clinical rating scales. Motor activity is an objective observation of the inner ...
Online Identification of Groups of Flows Sharing a Network Bottleneck 
Hayes, David Andrew; Welzl, Michael; Ferlin, Simone; Ros, David; Islam, Safiqul (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Most Internet hosts today support multiple access technologies and network interfaces. Multipath transport protocols, like MPTCP, are being deployed (e.g., in smartphones), allowing transparent simultaneous use of multiple ...
Pan-cancer analysis of whole genomes 
ICGC/TCGA, Pan-Cancer Analysis; Campbell, Peter J.; Getz, Gad; Korbel, Jan O.; Stuart, Joshua M.; Jennings, Jennifer L.; Stein, Lincoln D.; Perry, Marc D.; Nahal-Bose, Hardeep K.; Ouellette, B.F. Francis; Li, Constance H.; Rheinbay, Esther; Nielsen, G. Petur; Sgroi, Dennis C.; Wu, Chin-Lee; Faquin, William C.; Deshpande, Vikram; Boutros, Paul C. Boutros; Lazar, Alexander J.; Hoadley, Katherine A.; Louis, David N.; Dursi, L. Jonathan; Garred, Øystein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Cancer is driven by genetic change, and the advent of massively parallel sequencing has enabled systematic documentation of this variation at the whole-genome scale1,2,3. Here we report the integrative analysis of 2,658 ...
HyperKvasir, a comprehensive multi-class image and video dataset for gastrointestinal endoscopy 
Borgli, Hanna; Thambawita, Vajira; Smedsrud, Pia H; Hicks, Steven; Jha, Debesh; Eskeland, Sigrun Losada; Randel, Kristin Ranheim; Pogorelov, Konstantin; Lux, Mathias; Dang Nguyen, Duc Tien; Johansen, Dag; Griwodz, Carsten; Stensland, Håkon Kvale; Garcia-Ceja, Enrique; Schmidt, Peter T; Hammer, Hugo Lewi; Riegler, Michael; Halvorsen, Pål; de Lange, Thomas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Artificial intelligence is currently a hot topic in medicine. However, medical data is often sparse and hard to obtain due to legal restrictions and lack of medical personnel for the cumbersome and tedious process to ...
A Subjectivist Approach to Team Entrepreneurship 
Leunbach, Daniel; Erikson, Truls; Bjørnåli, Ekaterina S. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Many scholars have pointed to Austrian subjectivism as an appropriate framework for understanding and studying entrepreneurship. Yet very few empirical studies in the field of entrepreneurship have applied a subjectivist ...
Effectual tactics in digital intrapreneurship: A process model 
Vassilakopoulou, Polyxeni; Grisot, Miria (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Uncertainty and the pursuit of new ventures are intricately linked. Digital technologies open up new ways for uncertainty handling in the pursuit of novelty. In this paper, we develop a process model that traces the dynamics ...
Adaptive context encoding module for semantic segmentation 
Wang, Congcong; Alaya Cheikh, Faouzi; Beghdadi, Azeddine; Elle, Ole Jacob (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
The object sizes in images are diverse, therefore, capturing multiple scale context information is essential for semantic segmentation. Existing context aggregation methods such as pyramid pooling module (PPM) and atrous ...
Towards a video quality assessment based framework for enhancement of laparoscopic videos 
Khan, Zohaib Amjad; Beghdadi, Azeddine; Alaya Cheikh, Faouzi; Kaaniche, Mounir; Pelanis, Egidijus; Palomar, Rafael; Fretland, Åsmund Avdem; Edwin, Bjørn; Elle, Ole Jacob (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Laparoscopic videos can be affected by different distortions which may impact the performance of surgery and introduce surgical errors. In this work, we propose a framework for automatically detecting and identifying such ...
Use of mixed reality for surgery planning: Assessment and development workflow 
Kumar, Rahul Prasanna; Pelanis, Egidijus; Bugge, Robin Antony Birkeland; Brun, Henrik; Palomar, Rafael; Aghayan, Davit; Fretland, Åsmund Avdem; Edwin, Bjørn; Elle, Ole Jacob (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Meticulous preoperative planning is an important part of any surgery to achieve high levels of precision and avoid complications. Conventional medical 2D images and their corresponding three-dimensional (3D) reconstructions ...
Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-D-phosphohexomutase superfamily 
Backe, Paul Hoff; Lærdahl, Jon Kristen; Kittelsen, Lene Svendsen; Dalhus, Bjørn; Mørkrid, Lars; Bjørås, Magnar (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Human phosphoglucomutase 1 (PGM1) is an evolutionary conserved enzyme that belongs to the ubiquitous and ancient α-d-phosphohexomutases, a large enzyme superfamily with members in all three domains of life. PGM1 catalyzes ...
Augmenting the algorithm: emerging human-in-the-loop work configurations 
Grønsund, Tor Rolfsen; Aanestad, Margunn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
How do configurations of humans and algorithms evolve as firms adopt artificial intelligence (AI) capabilities, and what are the implications for work and organization? We explored these questions through a two-year long ...
Digital Ecosystems as a Unit of Scientific Analysis. A Sociological Investigation 
Bygstad, Bendik; Dulsrud, Arne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
The growth of digital ecosystems such as Google, Apple and Uber has led to radical changes in economic activity, work and consumption. It has also challenged established economic, social and organization theory, which has ...
Comparing manual and automatic scoring of sleep monitoring data from portable polygraphy 
Kristiansen, Stein; Traaen, Gunn Marit; Øverland, Britt; Plagemann, Thomas Peter; Gullestad, Lars; Akre, Harriet; Nikolaidis, Konstantinos; Aakerøy, Lars; Hunt, Tove Elizabeth Frances; Loennechen, Jan Pål; Steinshamn, Sigurd Loe; Bendz, Christina; Anfinsen, Ole-Gunnar; Goebel, Vera Hermine (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
We used sleep monitoring data from a study that investigated the prevalence, characteristics, risk factors and type of sleep apnea (SA) in 579 patients with paroxysmal atrial fibrillation. Most patients were screened for ...
The uracil-DNA glycosylase UNG protects the fitness of normal and cancer B cells expressing AID 
Safavi, Shiva; Larouche, Ariane; Zahn, Astrid; Patenaude, Anne-Marie; Domanska, Diana Ewa; Dionne, Kiersten; Rognes, Torbjørn; Dingler, Felix; Kang, Seong-Kwi; Liu, Yan; Johnson, Nathalie; Hébert, Josée; Verdun, Ramiro E.; Rada, Cristina; Vega, Francisco; Nilsen, Hilde; Di Noia, Javier M. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract In B lymphocytes, the uracil N-glycosylase (UNG) excises genomic uracils made by activation-induced deaminase (AID), thus underpinning antibody gene diversification and oncogenic chromosomal translocations, ...
Brain Modeling ToolKit: An open source software suite for multiscale modeling of brain circuits 
Dai, Kael; Gratiy, Sergey L.; Billeh, Yazan; Xu, Richard; Cai, Binghuang; Cain, Nicholas; Rimehaug, Atle Eskeland; Stasik, Alexander Johannes; Einevoll, Gaute; Mihalas, Stefan; Koch, Christof; Arkhipov, Anton (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Experimental studies in neuroscience are producing data at a rapidly increasing rate, providing exciting opportunities and formidable challenges to existing theoretical and modeling approaches. To turn massive datasets ...
Shifting conceptualization of control in agile transformations 
Mikalsen, Marius; Stray, Viktoria; Moe, Nils Brede; Backer, Idun (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract Agile transformation implies that organizations apply agile methods also outside of software development units. One particular way of doing such transformations is to create cross-functional software development ...
edgeTrans - Edge transport mode detection 
Ferreira, Paulo; Zavgorodnii, Constantin; Veiga, Luìs (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Automatic human activity detection, mainly transport-wise, is very relevant for architects and urban planners (among many others) when designing cities, roads, public transportation systems, etc. Such detection allows to ...
Tiårsprediksjon av hjerte-og karsykdom hos friske norske menn basert på NORRISK-2 
Mirza, Yusuf; Prestgaard, Erik Edvard; Selmer, Randi Marie; Liestøl, Knut; Grundvold, Irene; Erikssen, Jan Emil; Kjeldsen, Sverre; Gjesdal, Knut (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
BAKGRUNN Norske retningslinjer for primærforebygging av hjerte- og karsykdom anbefaler bruk av risikoskårmodellen NORRISK-2, med noen tillegg. Vi ønsket å undersøke om NORRISK-2 kunne predikere hjerte- og karsykdom hos ...
A Framework for Flexible Program Evolution and Verification of Distributed Systems 
Owe, Olaf; Fazeldehkordi, Elahe; Lin, Jia-Chun (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Program evolution may reveal bad design decisions, misunderstandings, erroneous code, or erroneous specifications, because problems made early in the design of a system may not be discovered until much later in the life-time ...
Automatic detection of valve events by epicardial accelerometer allows estimation of the left ventricular pressure trace and pressure–displacement loop area 
Wajdan, Ali; Krogh, Magnus Reinsfelt; Villegas-Martinez, Manuel; Halvorsen, Per Steinar; Elle, Ole Jacob; Remme, Espen W. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Abstract Measurements of the left ventricular (LV) pressure trace are rarely performed despite high clinical interest. We estimated the LV pressure trace for an individual heart by scaling the isovolumic, ejection and ...
A framework for automatic behavior generation in multi-function swarms 
Engebråten, Sondre Andreas; Moen, Jonas; Yakimenko, Oleg A.; Glette, Kyrre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Multi-function swarms are swarms that solve multiple tasks at once. For example, a quadcopter swarm could be tasked with exploring an area of interest while simultaneously functioning as ad-hoc relays. With this type of ...
Robust airborne ultrasonic positioning of moving targets in weak signal coverage areas 
Aparicio, Joaquin; Aguilera, Teodoro; Alvarez, Fernando J. (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
Current ultrasonic Local Positioning Systems (LPS) based on an infrastructure of beacons can provide centimeter-level accuracy employing the spread spectrum technique, which also adds robustness against noise. However, the ...
Overview of the ImageCLEF 2020: Multimedia Retrieval in Medical, Lifelogging, Nature, and Internet Applications 
Ionescu, Bogdan; Müller, Henning; Péteri, Renaud; Abacha, Asma Ben; Datla, Vivek; Hasan, Sadid A.; Demner-Fushman, Dina; Kozlovski, Serge; Liauchuk, Vitali; Cid, Yashin Dicente; Kovalev, Vassili; Pelka, Obioma; Friedrich, Christoph M.; García Seco de Herrera, Alba; Ninh, Van-Tu; Le, Tu-Khiem; Zhou, Liting; Piras, Luca; Riegler, Michael; Halvorsen, Pål; Tran, Minh-Triet; Lux, Mathias; Gurrin, Cathal; Dang Nguyen, Duc Tien; Chamberlain, Jon; Clark, Adrian; Campello, Antonio; Fichou, Dimitri; Berari, Raul; Brie, Paul; Dogariu, Mihai; Ştefan, Liviu Daniel; Constantin, Mihai Gabriel (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
This paper presents an overview of the ImageCLEF 2020 lab that was organized as part of the Conference and Labs of the Evaluation Forum - CLEF Labs 2020. ImageCLEF is an ongoing evaluation initiative (first run in 2003) ...
Assessing graph-based read mappers against a baseline approach highlights strengths and weaknesses of current methods 
Grytten, Ivar; Rand, Knut D; Nederbragt, Alexander J; Sandve, Geir K (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background Graph-based reference genomes have become popular as they allow read mapping and follow-up analyses in settings where the exact haplotypes underlying a high-throughput sequencing experiment are ...
Measuring intracranial pressure by invasive, less invasive or non-invasive means: limitations and avenues for improvement 
Evensen, Karen B; Eide, Per K (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Sixty years have passed since neurosurgeon Nils Lundberg presented his thesis about intracranial pressure (ICP) monitoring, which represents a milestone for its clinical introduction. Monitoring of ICP has since become a ...
Guiding Neuroevolution with Structural Objectives 
Ellefsen, Kai Olav; Huizinga, Joost; Tørresen, Jim (Journal article / Tidsskriftartikkel / SubmittedVersion, 2020)
The structure and performance of neural networks are intimately connected, and by use of evolutionary algorithms, neural network structures optimally adapted to a given task can be explored. Guiding such neuroevolution ...
A comparative node evaluation model for highly heterogeneous massive‐scale Internet of Things‐Mist networks 
Shahraki, Amin; Geitle, Marius; Haugen, Øystein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Internet of Things (IoT) is a new technology that is driving the connection of billions of devices around the world. Because these devices are often resource‐constrained and very heterogeneous, this presents unique challenges. ...
Development of a targeted client communication intervention to women using an electronic maternal and child health registry: a qualitative study 
Bogale, Binyam; Mørkrid, Kjersti; O’Donnell, Brian; Ghanem, Buthaina; Abu Ward, Itimad; Abu Khader, Khadija; Isbeih, Mervett; Frost, Michael; Baniode, Mohammad; Hijaz, Taghreed; Awwad, Tamara; Rabah, Yousef; Frøen, J. F (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Background Targeted client communication (TCC) using text messages can inform, motivate and remind pregnant and postpartum women of timely utilization of care. The mixed results of the effectiveness of TCC interventions ...
Model checking starvation for resource-aware active objects with coloured petri nets 
Gkolfi, Anastasia; Johnsen, Einar Broch; Kristensen, Lars Michael; Yu, Ingrid Chieh (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
Dynamic resource provisioning is an important driver for pay-on-demand cloud computing. Virtualized resources open for resource awareness, such that applications may use resource management strategies to modify their ...
Speckle Reduction Using Adaptive Receive-Side Compounding 
Jensen, Are Charles; Austeng, Andreas (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2020)
A typical approach to reduce speckle in coherent imaging systems, is to average same-target images with different speckle realizations. We study settings where such realizations come from applying different transducer-array ...
Digital Transformation under a pandemic: A case study of Covid-19 contact tracing in Norway 
Gundersen, Ragnhild Bassøe; Dynestøl, Emilie Bauck; Nielsen, Petter; Sæbø, Johan Ivar; Thorseng, Anne Asmyr; Ulshagen, Andrea; Utvik, Vetle Alvenes (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2020)
In March 2020 the number of confirmed COVID-19 cases in Norway increased rapidly, and the efforts to trace contacts of positive cases were under severe pressure. Contact tracing in Norway is the responsibility of the ...
Automated Characterization of Muscle Architectural Variation in Ultrasound Images 
Kirkebø, Jan Egil; Werkhausen, Amelie; Seynnes, Olivier R.; Austeng, Andreas (Journal article / Tidsskriftartikkel / SubmittedVersion, 2020)
Fascicle (fiber bundle) orientation and length are useful parameters to infer the force potential of skeletal muscles. Ultrasound imaging is commonly used to determine fascicle characteristics. In most of the literature, ...
Efficient live and on-demand tiled HEVC 360 VR video streaming 
Jeppsson, Mattis; Espeland, Håvard; Kupka, Tomas; Langseth, Ragnar; Petlund, Andreas; Peng, Qiaoqiao; Xue, Chuansong; Johansen, Dag; Pogorelov, Konstantin; Stensland, Håkon Kvale; Griwodz, Carsten; Riegler, Michael; Halvorsen, Pål (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
360∘ panorama video displayed through Virtual Reality (VR) glasses or large screens offers immersive user experiences, but as such technology becomes commonplace, the need for efficient streaming methods of such high-bitrate ...
Service tasks of board of directors: A literature review and research agenda in an era of new governance practices 
Åberg, Carl; Bankewitz, Max; Knockaert, Mirjam (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
In their seminal review article on board of directors, Johnson, Daily, and Ellstrand (1996) distinguished between the control, service, and resource dependence tasks of the board and called for a stronger focus on board ...
Knowledge graph embedding for ecotoxicological effect prediction 
Myklebust, Erik Bryhn; Jimenez-Ruiz, Ernesto; Chen, Jiaoyan; Wolf, Raoul; Tollefsen, Knut-Erik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Exploring the effects of a chemical compound on a species takes a considerable experimental effort. Appropriate methods for estimating and suggesting new effects can dramatically reduce the work needed to be done by a ...
Embedding OWL ontologies with OWL2Vec 
Holter, Ole Magnus; Myklebust, Erik Bryhn; Chen, Jiaoyan; Jimenez-Ruiz, Ernesto (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
In this paper, we present a preliminary study to compute embeddings for OWL 2 ontologies by projecting the ontology axioms into a graph and performing (random) walks over the ontology graph to create a corpus of sentences. ...
Predictive Data Transformation Suggestions in Grafterizer Using Machine Learning 
Sajid, Saliha; Zernichow, Bjørn Marius von; Soylu, Ahmet; Roman, Dumitru (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Data preprocessing is a crucial step in data analysis. A substantial amount of time is spent on data transformation tasks such as data formatting, modification, extraction, and enrichment, typically making it more convenient ...
The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload 
Mohammadzadeh, Naiyereh; Lunde, Ida Gjervold; Andenæs, Kine; Strand, Mari Elen; Aronsen, Jan Magnus; Skrbic, Biljana; Marstein, Henriette; Bandlien, Caroline; Nygård, Ståle; Gorham, Joshua; Sjaastad, Ivar; Chakravarti, Shukti; Christensen, Geir Arve; Engebretsen, Kristin V Thunheim; Tønnessen, Theis (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Left ventricular (LV) dilatation is a key step in transition to heart failure (HF) in response to pressure overload. Cardiac extracellular matrix (ECM) contains fibrillar collagens and proteoglycans, important for maintaining ...
On the Utility of Unregulated IP DiffServ Code Point (DSCP) Usage by End Systems 
Barik, Runa; Welzl, Michael; Elmokashfi, Ahmed; Dreibholz, Thomas; Islam, Safiqul; Gjessing, Stein (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
DiffServ was designed to implement service provider quality of service (QoS) policies, where routers change and react upon the DiffServ Code Point (DSCP) in the IP header. However, nowadays, applications are beginning to ...
Biophysical Psychiatry—How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders. 
Mäki-Marttunen, Tuomo; Kaufmann, Tobias; Elvsåshagen, Torbjørn; Devor, Anna; Djurovic, Srdjan; Westlye, Lars Tjelta; Linne, Marja-Leena; Rietschel, Marcella; Schubert, Dirk; Borgwardt, Stefan; Efrim-Budisteanu, Magdalena; Bettella, Francesco; Halnes, Geir; Hagen, Espen; Næss, Solveig; Ness, Torbjørn V; Moberget, Torgeir; Metzner, Christoph; Edwards, Andrew G.; Fyhn, Marianne; Dale, Anders M.; Einevoll, Gaute T.; Andreassen, Ole Andreas (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
The brain is the most complex of human organs, and the pathophysiology underlying abnormal brain function in psychiatric disorders is largely unknown. Despite the rapid development of diagnostic tools and treatments in ...
Additive manufacturing of laminar flow cells for single-molecule experiments 
Ahmadi, Arash; Till, Katharina; Hafting, Yngve; Schuttpelz, Mark; Bjørås, Magnar; Glette, Kyrre; Tørresen, Jim; Rowe, Alexander D.; Dalhus, Bjørn (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
A microfluidic laminar flow cell (LFC) forms an indispensable component in single-molecule experiments, enabling different substances to be delivered directly to the point under observation and thereby tightly controlling ...
XTRA: Towards Portable Transport Layer Functions 
Bianchi, Giuseppe; Welzl, Michael; Tulumello, Angelo; Gringoli, Francesco; Belocchi, Giacomo; Faltelli, Marco; Pontarelli, Salvatore (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
XTRA (XFSM for Transport) aims at providing a first attempt towards a “code-once-port-everywhere” platform-agnostic programming abstraction tailored to the deployment of transport layer functions. XTRA's programming ...
Direct Synthesis of Carbon Nanotubes in CMOS-Layout of Micro-heaters 
Roy, Avisek; Azadmehr, Mehdi; Häfliger, Philipp; Ta, Bao Quoc; Aasmundtveit, Knut Eilif (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Direct integration of Carbon Nanotubes (CNTs) in CMOS is important for commercially manufacturing low-cost CNT-based sensors. In such compact sensors, CNTs would act as sensing element, and CMOS circuits would process ...
Improved Lesion Detection Using Nonlocal Means Post-Processing 
Rindal, Ole Marius Hoel; Rodriguez-Molares, Alfonso; Måsøy, Svein-Erik; Bjåstad, Tore Grüner (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Software beamforming allows more flexible and complex algorithms, often referred to as adaptive beamforming techniques, that are blurring the boundaries between beamforming and image processing. Many adaptive beamforming ...
Efficient routing and reconfiguration in virtualized HPC environments with vSwitch-enabled lossless networks 
Tasoulas, Evangelos; Zahid, Feroz; Gran, Ernst Gunnar; Begnum, Kyrre; Johnsen, Bjørn Dag; Skeie, Tor (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
To meet the demands of communication‐intensive workloads in the cloud, virtual machines (VMs) should utilize low overhead network communication paradigms. In general, such paradigms enable VMs to directly communicate with ...
A clinico-molecular predictor identifies follicular lymphoma patients at risk of early transformation after first-line immunotherapy 
Steen, Chloe Beate; Leich, Ellen; Myklebust, June Helen; Lockmer, Sandra; Wise, Jillian; Wahlin, Björn Engelbrekt; Østenstad, Bjørn; Liestøl, Knut; Kimby, Eva; Rosenwald, Andreas; Smeland, Erlend B; Holte, Harald; Lingjærde, Ole Christian; Brodtkorb, Marianne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Bridging analog and digital expertise: Cross-domain collaboration and boundary-spanning tools in the creation of digital innovation 
Pershina, Raissa; Soppe, Birthe; Thune, Taran Mari (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Expertise in digital technologies is necessary, but rarely sufficient to generate digital innovation. The purpose of this paper is to explore how specialists rooted in digital and analog knowledge domains engage in ...
On the Effect of Word Order on Cross-lingual Sentiment Analysis 
R. Atrio, Alex; Badia, Toni; Barnes, Jeremy Claude (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Current state-of-the-art models for sentiment analysis make use of word order either explicitly by pre-training on a language modeling objective or implicitly by using recurrent neural networks (Rnns) or convolutional ...
Design of a 900 MHz dual-mode SWIPT for low-power IoT devices 
Abbasizadeh, Hamed; Kim, Sang-Yun; Samadpoor Rikan, Behnam; Hejazi, Arash; Khan, Danial; Pu, Young Gun; Hwang, Keum Cheol; Yang, Youngoo; Kim, Dong In; Lee, Kang-Yoon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
This paper presents a duty cycle-based, dual-mode simultaneous wireless information and power transceiver (SWIPT) for Internet of Things (IoT) devices in which a sensor node monitors the received power and adaptively ...
A stable non-interleaving early operational semantics for the pi-calculus 
Hildebrandt, Thomas; Johansen, Christian; Norman, Håkon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
We give the first non-interleaving early operational semantics for the pi-calculus which generalises the standard interleaving semantics and unfolds to the stable model of prime event structures. Our starting point is the ...
Integrative genomic analysis of peritoneal malignant mesothelioma: Understanding a case with extraordinary chemotherapy response 
Lund-Andersen, Christin; Nakken, Sigve; Nygård, Ståle; Fromm, Bastian; Aasheim, Lars Birger; Davidson, Ben; Julsrud, Lars; Abrahamsen, Torveig Weum; Kristensen, Annette Torgunrud; Dybdahl, Brit; Larsen, Stein Gunnar; Hovig, Eivind; Flatmark, Kjersti (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Peritoneal malignant mesothelioma is a rare disease with a generally poor prognosis and poor response to chemotherapy. To improve survival there is a need for increased molecular understanding of the disease, including ...
Some elements to a theory of digital management 
Bygstad, Bendik; Lanestedt, Gjermund; Iden, Jon (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Is digital management something else than general management? In this paper we contend that it is, both theoretically and in practice. To develop our argument, we suggest a framework for understanding the particular aspects ...
Arrhythmogenic Current Generation by Myofilament-Triggered Ca2+ Release and Sarcomere Heterogeneity 
Timmermann, Viviane; Edwards, Andrew; Wall, Samuel Thomas; Sundnes, Joakim; McCulloch, Andrew D. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Heterogeneous mechanical dyskinesis has been implicated in many arrhythmogenic phenotypes. Strain-dependent perturbations to cardiomyocyte electrophysiology may contribute to this arrhythmogenesis through processes referred ...
Graph Peak Caller: Calling ChIP-seq peaks on graph-based reference genomes 
Grytten, Ivar; Rand, Knut Dagestad; Nederbragt, Alexander Johan; Storvik, Geir Olve; Glad, Ingrid Kristine; Sandve, Geir Kjetil (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Graph-based representations are considered to be the future for reference genomes, as they allow integrated representation of the steadily increasing data on individual variation. Currently available tools allow de novo ...
Godot: All the benefits of implicit and explicit futures 
Fernandez-Reyes, Kiko; Clarke, Dave; Henrio, Ludovic; Johnsen, Einar Broch; Wrigstad, Tobias (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Concurrent programs often make use of futures, handles to the results of asynchronous operations. Futures provide means to communicate not yet computed results, and simplify the implementation of operations that synchronise ...
Scar shape analysis and simulated electrical instabilities in a non-ischemic dilated cardiomyopathy patient cohort 
Balaban, Gabriel; Halliday, Brian P; Bai, Wenjia; Porter, Bradley; Malvuccio, Carlotta; Lamata, Pablo; Rinaldi, Christopher Aldo; Plank, Gernot; Rueckert, Daniel; Prasad, Sanjay Kant; Bishop, Martin (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
This paper presents a morphological analysis of fibrotic scarring in non-ischemic dilated cardiomyopathy, and its relationship to electrical instabilities which underlie reentrant arrhythmias. Two dimensional electrophysiological ...
Doppler resilience evaluation of different encoding techniques for underwater acoustic ranging systems 
Murano, Santiago; Perez-Rubio, Carmen; Aparicio, Joaquin; De Marziani, Carlos (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Underwater acoustic communication or localization systems can be affected by the Doppler effect when the receiver or emitter is in motion. In those cases, the use of an a appropiate encoding/modulating scheme play a pivotal ...
Results of multigene panel testing in familial cancer cases without genetic cause demonstrated by single gene testing 
Dominguez-Valentin, Mev; Nakken, Sigve; Tubeuf, Hélène; Vodák, Daniel; Ekstrøm, Per Olaf; Nissen, Anke M.; Morak, Monika; Holinski-Feder, Elke; Holth, Arild; Capellá, Gabriel M.; Davidson, Ben; Evans, D. Gareth; Martins, Alexandra; Møller, Pål; Hovig, Eivind (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
We have surveyed 191 prospectively sampled familial cancer patients with no previously detected pathogenic variant in the BRCA1/2, PTEN, TP53 or DNA mismatch repair genes. In all, 138 breast cancer (BC) cases, 34 colorectal ...
User validation in ontology alignment: functional assessment and impact 
Huanyu, Li; Dragisic, Zlatan; Faria, Daniel; Ivanova, Valentina; Jimenez-Ruiz, Ernesto; Lambrix, Patrick; Pesquita, Catia (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
User validation is one of the challenges facing the ontology alignment community, as there are limits to the quality of the alignments produced by automated alignment algorithms. In this paper, we present a broad study on ...
Flexible device compositions and dynamic resource sharing in PCIe interconnected clusters using Device Lending 
Markussen, Jonas Sæther; Kristiansen, Lars Bjørlykke; Borgli, Rune Johan; Stensland, Håkon Kvale; Seifert, Friedrich; Riegler, Michael Alexander; Griwodz, Carsten; Halvorsen, Pål (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
Modern workloads often exceed the processing and I/O capabilities provided by resource virtualization, requiring direct access to the physical hardware in order to reduce latency and computing overhead. For computers ...
Canonicalizing Knowledge Base Literals 
Chen, Jiaoyan; Jimenez-Ruiz, Ernesto; Horrocks, Ian (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
Ontology-based knowledge bases (KBs) like DBpedia are very valuable resources, but their usefulness and usability are limited by various quality issues. One such issue is the use of string literals instead of semantically ...
Mitral Annulus Segmentation Using Deep Learning in 3-D Transesophageal Echocardiography 
Andreassen, Børge Solli; Veronesi, Federico; Gerard, Olivier; Solberg, Anne H Schistad; Samset, Eigil (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
3D Transesophageal Echocardiography is an excellent tool for evaluating the mitral valve and is also well suited for guiding cardiac interventions. We introduce a fully automatic method for mitral annulus segmentation in ...
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