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Now showing items 1201-1300 of 3153
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The association between pulmonary sequelae and markers of disease severity, as well as pro-fibrotic mediators, were studied in 108 patients 3 months after hospital admission for COVID-19. The COPD assessment test (CAT-score), ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Importance: White matter (WM) abnormalities are commonly reported in psychiatric disorders. Whether peripartum insufficiencies in brain oxygenation, known as birth asphyxia, are associated with WM of patients with severe ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background: Monitoring dietary habits is important in order to identify risk groups and as a basis for targeted public health initiatives.
Objective: To study trends in consumption of selected foods and beverages from ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract
The soil bacterium Burkholderia pseudomallei is the causative agent of melioidosis and a significant cause of human morbidity and mortality in many tropical and subtropical countries. The species notoriously ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Scope
The aim of this study is to explore the molecular mechanisms underlying the effect of replacing dietary saturated fat (SFA) with polyunsaturated fat (PUFA) on cardiovascular disease (CVD) risk using a whole ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract Learning vector autoregressive models from multivariate time series is conventionally approached through least squares or maximum likelihood estimation. These methods typically assume a fully connected model which ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background: Vascular pathology is a common feature in patients with advanced Alzheimer’s disease, with cerebral amyloid angiopathy (CAA) and microvascular changes commonly observed at autopsies and in genetic mouse models. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Tumor-specific T helper (Th) cells have a central role in the immune response against cancer. However, there exist distinct Th cell subsets with very different and antagonizing properties. Some Th subsets such as Th1 protect ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Loss-of-function mutations in the skin barrier gene filaggrin (FLG) increase the risk of atopic dermatitis (AD), but their role in skin barrier function, dry skin and eczema in infancy is unclear.
Objectives
To ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Microfluidics have been used for several decades to conduct a wide range of research in chemistry and the life sciences. The reduced dimensions of these devices give them advantages over classical analysis techniques such ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Neisseria meningitidis (the meningococcus) is a major human pathogen with a history of high invasive disease burden, particularly in sub-Saharan Africa. Our current understanding of the evolution of meningococcal genomes ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract Alternative Lengthening of Telomeres (ALT) is a telomere maintenance pathway utilised in 15% of cancers. ALT cancers are strongly associated with inactivating mutations in ATRX ; yet loss of ATRX alone is insufficient ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract The endothelium acts as the barrier that prevents circulating lipids such as lipoproteins and fatty acids into the arterial wall; it also regulates normal functioning in the circulatory system by balancing ...
(Journal article / Tidsskriftartikkel / PublishedVersion, 2021)
This work introduces a strategy for organoid analysis - direct Electromembrane Extraction based Mass Spectrometry (dEME-MS) – for coupling liver organoids with mass spectrometry (MS). dEME-MS comprises electrophoresis of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Mesenchymal stem cells (MSCs) are being widely researched upon for several years with translational application in regenerative medicine. Many studies acknowledged trophic factors from MSCs, attenuating dreadful ailments. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Cancer cells survive and grow despite various advanced anti-cancer therapy. To overcome this antineoplastic resistance, adjuvant therapy is often required to prevent cancer cells' immunoescape capacity. Established tumors ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The cardiac sodium–calcium exchanger (NCX1) is important for normal Na + - and Ca 2+ -homeostasis and cardiomyocyte relaxation and contraction. It has been suggested that NCX1 activity is reduced by phosphorylated phospholemman ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract
Background
Bacterial whole-genome sequencing based on short-read technologies often results in a draft assembly formed by contiguous sequences. The introduction of long-read ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Introduction: Carbohydrate intake and physical activity are related to glucose homeostasis, both being influenced by individual genetic makeup. However, the interactions between these 2 factors, as affected by genetics, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Imaging the intact brain of awake behaving mice without the dampening effects of anesthesia, has revealed an exceedingly rich repertoire of astrocytic Ca 2+ signals. Analyzing and interpreting such complex signals pose ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Pain habituation is associated with a decrease of activation in brain areas related to pain perception. However, little is known about the specificity of these decreases to pain, as habituation has also been described for ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
During the last trimester of gestation and for the first 18 months after birth, both docosahexaenoic acid,22:6n-3 (DHA) and arachidonic acid,20:4n-6 (ARA) are preferentially deposited within the cerebral cortex at a rapid ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Skeletal muscle plays an important role in glycaemic control and metabolic homeostasis, making it a tissue of interest with respect to type 2 diabetes mellitus. The aim of the present study was to determine if ligands of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract
Purpose of Review
Beta cell replacement therapy as a form of islet transplantation is a promising alternative therapy with the possibility to make selected patients with type 1 diabetes (T1D) ...
(Journal article / Tidsskriftartikkel / PublishedVersion, 2021)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Objectives: Open surgical tracheostomy (OST) is a common procedure performed on intensive care unit (ICU) patients. The procedure can be performed bedside in the ICU (bedside open surgical tracheostomy, BeOST) or in the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Summary
We present a method for estimating several prognosis parameters for cancer survivors. The method utilizes the fact that these parameters solve differential equations driven by cumulative hazards. By ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Objectives To examine age at diagnosis, prognostic factors and survival of prostate cancer (PCa) in Norwegian firefighters and three other occupations undergoing occupational health check-ups, and comparing with PCa cases ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Patients’ phenotypic characteristics might be associated with melanoma aggressiveness, but the evidence is scarce. This study examined the associations between pigmentary characteristics, naevi and melanoma thickness. ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Obesity is associated with increased muscle mass and muscle strength. Methods taking into account the total body mass to reveal obese older individuals at increased risk of functional impairment are needed. Therefore, we ...
(Journal article / Tidsskriftartikkel / PublishedVersion, 2021)
This editorial review of the Research Topic Appning describes several solutions to support the sharing of animal imaging data and processing tools. Appning promotes the federation of multiple sources of information, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract The FDA recently approved eight targeted therapies for acute myeloid leukemia (AML), including the BCL-2 inhibitor venetoclax. Maximizing efficacy of these treatments requires refining patient selection. To this ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Objective
Explore sequential patterns in students’ interactions with patients expressing emotional concerns in a medical interview.
Methods
Concepts and principles from conversation analysis (CA) were used to examine ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Understanding the impacts of activity on energy balance is crucial. Increasing levels of activity may bring diminishing returns in energy expenditure because of compensatory responses in non-activity energy expenditures.1, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Open and reproducible research practices increase the reusability and impact of scientific research. The reproducibility of research results is influenced by many factors, most of which can be addressed by improved education ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract
Background
Illicitly manufactured fentanyl and its analogs are a major driving force behind the ongoing opioid crisis. Cyclopropylfentanyl is a fentanyl analog associated with many overdose ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Introduction
Elevated homocysteine (Hcy) and related metabolites accelerate Alzheimer's disease. Hcy-lowering B vitamins slow brain atrophy/cognitive decline in mild cognitive impairment (MCI). Modification with ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Tankyrase 1 and 2 (TNKS1/2) catalyze post-translational modification by poly-ADP-ribosylation of a plethora of target proteins. In this function, TNKS1/2 also impact the WNT/β-catenin and Hippo signaling pathways that are ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Introduction Patients with advanced chronic obstructive pulmonary disease (COPD) experience a great symptom burden. Breathlessness is a very frequently reported symptom that negatively affects all aspects of daily life and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
In vertebrates, the anterior pituitary plays a crucial role in regulating several essential physiological processes via the secretion of at least seven peptide hormones by different endocrine cell types. Comparative and ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Abstract The association between fish consumption and decreased risk of CVD is well documented. However, studies on health effects of fish consumption suggest that other components than n -3 PUFA have beneficial cardiometabolic ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Objective
Burnout is commonly associated with low workplace wellbeing. Patients with eating disorders are frequently referred to as a particularly challenging group to treat. It is therefore important to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract Fibrotic scar tissue limits central nervous system regeneration in adult mammals. The extent of fibrotic tissue generation and distribution of stromal cells across different lesions in the brain and spinal cord ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The alkaline comet assay, or single cell gel electrophoresis, is one of the most popular methods for assessing DNA damage in human population. One of the open issues concerning this assay is the identification of those ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
COVID-19 has shown that international collaborations and global data sharing are essential for health research, but legal obstacles are preventing data sharing for non–pandemic-related research among public researchers ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Objective
Explore medical students’ verbal responses to patients expressing emotional issues in a medical interview.
Methods
Eleven third-year students were instructed to conduct a medical interview with a simulated ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Total daily energy expenditure (“total expenditure”) reflects daily energy needs and is a critical variable in human health and physiology, but its trajectory over the life course is poorly studied. We analyzed a large, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Klebsiella species occupy a wide range of environmental and animal niches, and occasionally cause opportunistic infections that are resistant to multiple antibiotics. In particular, Klebsiella pneumoniae (Kpne) has gained ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Neurons that signal the angular velocity of head movements (AHV cells) are important for processing visual and spatial information. However, it has been challenging to isolate the sensory modality that drives them and to ...
(Journal article / Tidsskriftartikkel / PublishedVersion, 2021)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
ADP-ribosylation, a modification of proteins, nucleic acids, and metabolites, confers broad functions, including roles in stress responses elicited, for example, by DNA damage and viral infection and is involved in intra- ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
T cells play a key role in the pathogenesis of multiple sclerosis (MS), a chronic, inflammatory, demyelinating disease of the central nervous system (CNS). Although several studies recently investigated the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract School meal guidelines can be important tools to promote children’s diets, but their implementation depends on several influencing factors. Understanding these is important for designing effective interventions ...
(Master thesis / Masteroppgave, 2021)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Measuring molecular evolution in bacteria typically requires estimation of the rate at which nucleotide changes accumulate in strains sampled at different times that share a common ancestor. This approach has been useful ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Motivation: Mapping of chromatin accessibility landscapes in single-cells and the integration with gene expression enables a better understanding of gene regulatory mechanisms defining cell identities and cell-fate ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Long-COVID-19 is a proposed syndrome negatively affecting the health of COVID-19 patients. We present data on self-rated health three to eight months after laboratory confirmed COVID-19 disease compared to a control group ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Research indicates reduced physical performance from diagnosis into survivorship of pediatric cancer patients. However, there is no systematic information or guideline available on the methods to assess ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Therapeutic hypothermia following neonatal encephalopathy due to birth asphyxia reduces death and cerebral palsy. However, school-age children without cerebral palsy treated with therapeutic hypothermia for neonatal ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background Female athletes might develop reduced bone mineral density (BMD) and amenorrhoea due to low energy intake. Objective To systematically review the literature of randomised controlled trials (RCTs) assessing the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Neglected diseases caused by arenaviruses such as Lassa virus (LASV) and filoviruses like Ebola virus (EBOV) primarily afflict resource-limited countries, where antiviral drug development is often minimal. Previous studies ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Escherichia coli is a highly diverse organism that includes a range of commensal and pathogenic variants found across a range of niches and worldwide. In addition to causing severe intestinal and extraintestinal disease, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The pan-genome is defined as the combined set of all genes in the gene pool of a species. Pan-genome analyses have been very useful in helping to understand different evolutionary dynamics of bacterial species: an open ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Autophagy is a fundamental catabolic process that uses a unique post-translational modification, the conjugation of ATG8 protein to phosphatidylethanolamine (PE). ATG8 lipidation also occurs during non-canonical autophagy, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background and Aim: Real world evidence on long term treatment of patients with familial hypercholesterolemia (FH) is important. We studied the effects of intensive lipid lowering medication (LLM) and optimized lifestyle ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
To elucidate the contributions of specific lipid species to metabolic traits, we integrated global hepatic lipid data with other omics measures and genetic data from a cohort of about 100 diverse inbred strains of mice fed ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
For a number of years, facial features removal techniques such as ‘defacing’, ‘skull stripping’ and ‘face masking/blurring’, were considered adequate privacy preserving tools to openly share brain images. Scientifically, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Determining the composition of bacterial communities beyond the level of a genus or species is challenging because of the considerable overlap between genomes representing close relatives. Here, we present the mSWEEP ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract Chickens are the most common birds on Earth and colibacillosis is among the most common diseases affecting them. This major threat to animal welfare and safe sustainable food production is difficult to combat ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract
Study objectives
The aim of this study was to validate the automatically scored results of an esophageal probe–based polygraph system (ApneaGraph ® Spiro) against manually scored polysomnography ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Binary prediction-models for outcome [death, cognition, presence and severity of cerebral palsy (CP)], using MRI and early clinical data applicable for individual outcome prediction have not been developed. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract In the past few years, social epistemologists have developed several formal models of the social organisation of science. While their robustness and representational adequacy has been analysed at length, the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract
During a citywide microbiological screening project in Pavia (Italy) a bacterial strain isolated from the surface of an Automated Teller Machine was classified as a Klebsiella sp. by MALDI-TOF spectrometry, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Human telomerase reverse transcriptase (hTERT) remains suppressed in most normal somatic cells. Resulting erosion of telomeres leads eventually to replicative senescence. Reactivation of hTERT maintains telomeres and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Few randomized clinical trials have explored the health effects of bilberries in humans. The aim was to test the effect of bilberry and red grape-juice consumption on visual memory, motor speed ...
Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Nonadherence to drugs is a challenge in hypertension treatment. We aimed to assess the prevalence of nonadherence by serum drug concentrations compared with 2 indirect methods and relate to the prescribed drug regimens in ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The apolipoprotein E gene ε4 allele (APOE ε4) and higher circulating level of C-reactive protein (CRP) have been extensively investigated as risk factors for Alzheimer’s disease (AD). Paradoxically, APOE ε4 has been ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract Fibrosis accompanies most heart diseases and is associated with adverse patient outcomes. Transforming growth factor (TGF)β drives extracellular matrix remodelling and fibrosis in the failing heart. Some members ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The world was unprepared for coronavirus disease 2019 (COVID-19) and remains ill-equipped for future pandemics. While unprecedented strides have been made developing vaccines and treatments for COVID-19, there remains a ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Research at the Oslo Cyclotron Laboratory at the University of Oslo is focused on spectroscopy experiments for nuclear structure and nuclear astrophysics using the Oslo Scintillator Array OSCAR. Light-ion beams from the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract Legionella pneumophila is the most common cause of the severe respiratory infection known as Legionnaires’ disease. However, the microorganism is typically a symbiont of free-living amoeba, and our understanding ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Objective: To examine whether 5 years of high-intensity interval training (HIIT) increases high-density lipoprotein cholesterol (HDL-C) concentration more than moderate-intensity continuous training (MICT) and control (CON) ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background: Metals, silicon, and homocysteine are linked to Alzheimer’s disease. B vitamin therapy lowers homocysteine and slows brain atrophy and cognitive decline in mild cognitive impairment (MCI). Objective: Examine ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The correct folding of proteins is essential for their activity. Therefore, cells have evolved protein-folding chaperones, such as Hsp90. Interestingly, in several cancer cells, Hsp90 appears to have a role that is more ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background:
The sarcoplasmic reticulum (SR) Ca2+-ATPase 2 (SERCA2) mediates Ca2+ reuptake into SR and thereby promotes cardiomyocyte relaxation, whereas the ryanodine receptor (RYR) mediates Ca2+ release from SR and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The incidence of infections caused by multidrug-resistant E. coli strains has risen in the past years. Antibiotic resistance in E. coli is often mediated by acquisition and maintenance of plasmids. The study of E. coli ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Epigenetic targeting has emerged as an efficacious therapy for hematological cancers. The rare and incurable T-cell prolymphocytic leukemia (T-PLL) is known for its aggressive clinical course. Current epigenetic agents ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract. Background: Suicidal intent for patients attempting suicide using violent methods (VMs) is assumed to be higher than for those using self-poisoning (SP), which may explain the higher mortality observed in follow-up ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract Objective. Despite new strategies in tissue engineering, cartilage repair remains a major challenge. Our aim is to treat patients with focal lesions of articular cartilage with autologous hyaline cartilage implants ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The HIV-protease inhibitor nelfinavir has shown broad anticancer activity in various preclinical and clinical contexts. In patients with advanced, proteasome inhibitor (PI)–refractory multiple myeloma, nelfinavir-based ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Due to increasing demand, many traditional, grazing-based Mediterranean sheep production systems have introduced intensified feeding regimes, increased investments in infrastructure and drug use to increase milk yields. ...
Associations between muscle health and inflammaging in home-dwelling elderly Using peripheral blood mononuclear cell gene expression and bioinformatics tools Restricted Access
(Master thesis / Masteroppgave, 2021)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract
In 2002, a transmembrane protein—now known as FNDC5—was discovered and shown to be expressed in skeletal muscle, heart, and brain. It was virtually ignored for 10 years, until a study in 2012 proposed ...
CT-derived body composition in stage I-III colorectal cancer patients pre- and post-surgery. Restricted Access
(Master thesis / Masteroppgave, 2021)
The effect of dietary omega-3 fatty acids on hippocampal synaptic glutamate receptors: An electron microscopical investigation Restricted Access
(Master thesis / Masteroppgave, 2021)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract Despite decades of intensive search for compounds that modulate the activity of particular protein targets, a large proportion of the human kinome remains as yet undrugged. Effective approaches are therefore ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Brain age is a widely used index for quantifying individuals’ brain health as deviation from a normative brain aging trajectory. Higher-than-expected brain age is thought partially to reflect above-average rate of brain ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract
Background
To make effective progress towards a global reduction in obesity prevalence, there needs to be a focus on broader structural factors, beyond individual-level drivers ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
HEK293 cells are one of the most widely used cell lines in research, and HEK293 cells are frequently used as an in vitro model for studying the WNT signaling pathway. The HEK293 cell line was originally established by ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The ubiquitin-proteasome system (UPS) and macroautophagy/autophagy are the main proteolytic systems in eukaryotic cells for preserving protein homeostasis, i.e., proteostasis. By facilitating the timely destruction of ...