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Now showing items 1001-1100 of 3150
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Dried blood spot (DBS) metabolite analysis is a central tool for the clinic, e.g., newborn screening. Instead of applying multiple analytical methods, a single liquid chromatography-mass spectrometry (LC–MS) method was ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Objective
β-cell replacement therapy (βCRT), including pancreas transplantation alone (PTA) and islet transplantation (ITX), is a treatment option for selected type 1 diabetes patients. All potential candidates for βCRT ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Introduction
Persistent dyspnea is common in follow-up after pulmonary embolism (PE), but the underlying mechanisms are poorly understood.
Material and methods
This cross-sectional study included subjects aged 18–75 ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background Patients awaiting kidney transplantation need to be prepared ahead of the upcoming transplantation by developing targeted pre- and post-transplant knowledge. On this background, we designed a new health literacy ...
Metabolic risk profile among women with pre-pregnancy overweight and obesity at 22-24 weeks postpartum Restricted Access
(Master thesis / Masteroppgave, 2021)
The use of malnutrition-related ICD-10 codes in Norwegian hospitals - a part of the QuaNuT-project Restricted Access
(Master thesis / Masteroppgave, 2021)
Vitamin D and calcium intake in children with Fontan circulation - In relationship to vitamin D status and bone mineral density Restricted Access
(Master thesis / Masteroppgave, 2021)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Introduction Traumatic injuries constitute a major cause of mortality and morbidity. Still, the public health burden of trauma in Norway has not been characterised using nationwide registry data. More knowledge is warranted ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract Neuroticism is associated with poor health, cardiovascular disease (CVD) risk factors and coronary artery disease (CAD). The conditional/conjunctional false discovery rate method (cond/conjFDR) was applied to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Objective
Overweight, defined as excessive fat mass, is a long-standing worldwide public health challenge. Traditional anthropometric measures used to identify overweight and obesity do not assess body composition. The ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
ABSTRACT
Macropinocytosis allows cells to take up extracellular material in a non-selective manner into large vesicles called macropinosomes. After internalization, macropinosomes acquire phosphatidylinositol ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Heritability is a central measure in genetics quantifying how much of the variability observed in a trait is attributable to genetic differences. Existing methods for estimating heritability are ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Cancer genomic studies often include data collected from several omics platforms. Each omics data source contributes to the understanding of the underlying biological process via source specific ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Prediction models should be externally validated to assess their performance before implementation. Several prediction models for coronavirus disease-19 (COVID-19) have been published. This observational ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract Gut mucosal barrier injury is common following allogeneic hematopoietic stem cell transplantation (allo-HSCT) and associated with poor clinical outcomes. Diet is critical for microbial diversity, but whether ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
C-type lectin-like domain family 16 member A (CLEC16A) is associated with autoimmune disorders, including multiple sclerosis (MS), but its functional relevance is not completely understood. CLEC16A is expressed in several ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Liver cell types derived from induced pluripotent stem cells (iPSCs) share the potential to investigate development, toxicity, as well as genetic and infectious disease in ways currently limited by the availability of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background: Choline is an essential nutrient involved in a wide range of physiological functions. It occurs in water- and lipid-soluble forms in the body and diet. Foods with a known high choline content are eggs, beef, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Introduction The metabolic activity of the gut microbiota plays a pivotal role in the gut-brain axis through the effects of bacterial metabolites on brain function and development. In this study we investigated the association ...
(Doctoral thesis / Doktoravhandling, 2021)
Patients with malignant blood disease treated with allogeneic stem cell transplantation (allo-HSCT) suffer from insufficient energy and protein intake leading to weight loss and malnutrition. Poor nutritional status has ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
High circulating levels of vitamin D (25(OH)D) are suggested to reduce the risk of urinary bladder cancer (BC), but the evidence is weak, and several studies lack sufficient adjustment for potential confounders ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Aims
To study whether the preparation procedure, and its acidic and heating conditions, used by heroin users to prepare heroin for intravenous administration affects the final composition of the fluid to be injected.
...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The impact of nutrition information on public health is partly determined by the population's level of nutrition literacy (NL), which involves functional NL (such as knowledge of dietary guidelines) and critical NL (such ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Physical inactivity and unhealthy diet are key behavioral determinants underlying obesity. The neighborhood environment represents an important arena for modifying these behaviors, and hence ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background: The UN Sustainable Development Goal (SDG) 2 (‘Zero Hunger’) aims to end all forms of hunger and malnutrition by 2030. Thus, a range of different strategies are needed to facilitate the achievement of SDG 2 to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background: The brief generic Multicultural Quality of Life Index (MQLI) is a culturally informed self-report 10-item questionnaire used to measure health-related quality of life (QoL). QoL is an important outcome measure ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
People on or at risk of sick leave from work due to obesity or obesity-related problems participated in a new vocational rehabilitation (VR). The study aimed to examine the outcome changes in ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The capacity of human brain to sustain complex cortical dynamics appears to be strongly associated with conscious experience and consistently drops when consciousness fades. For example, several recent studies in humans ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Purpose: We aimed to investigate which changes in the explanatory factors that were associated with positive change in the work ability score (WAS) and degree of work participation (DWP) for participants in a new 1-year ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Global longitudinal strain (GLS) is a more sensitive prognostic factor than left ventricular ejection fraction (LVEF) in various cardiac diseases. Little is known about the clinical impact of GLS changes after acute ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Our understanding of platelet functionality has undergone a sea change in the last decade. No longer are platelets viewed simply as regulators of haemostasis; they are now acknowledged to be pivotal in coordinating the ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Optimizing the possibility to lead good lives is at the core of treatment and care for people with dementia. This may be monitored by assessing well-being and quality of life. However, cognitive impairment following dementia ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
BAKGRUNN I norske studier er det dokumentert dårlig kardiovaskulær risikofaktorkontroll og høy forekomst av nye hjerte- og karhendelser hos hjerteinfarktpasienter. Det foreligger lite kunnskap om omfang av sekundærforebyggende ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract People’s ability to critically assess cancer-related information is essential from a preventional and therapeutic, as well as a general democratic perspective. Such cancer literacy is not just about acquiring ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background Cancer has been suggested as a risk factor for severe outcome of SARS-CoV-2 infection. In this population-based study we aimed to identify factors associated with higher risk of COVID-19 and adverse outcome. ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Enterococcus faecium is a commensal of the gastrointestinal tract of animals and humans but also a causative agent of hospital-acquired infections. Resistance against glycopeptides and to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Early events during development leading to exit from a pluripotent state and commitment toward a specific germ layer still need in depth understanding. Autophagy has been shown to play a crucial role in both development ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
High intratumoral levels of urokinase-type plasminogen activator (uPA)-plasminogen activator inhibitor-1 (PAI-1) heteromers predict impaired survival and treatment response in early breast cancer. The pathogenetic role of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract The role of dysfunction of the single ventricle in Fontan failure is incompletely understood. We aimed to evaluate hemodynamic responses to preload increase in Fontan circulation, to determine whether circulatory ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract
Motivation
Combination therapies have emerged as a powerful treatment modality to overcome drug resistance and improve treatment efficacy. However, the number of possible drug ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor whose physiological function is poorly understood. The AhR is highly expressed in barrier organs such as the skin, intestine, and lung. The ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background and aims
There are indications for tracking of circulating total cholesterol concentration (TC) from childhood to later in life. An increased lifelong TC exposure increases the risk of developing atherosclerosis, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Testing kinship between pairs of individuals is central to a wide range of applications. We focus on cases where many tests are done jointly. Typical examples include cases where DNA profiles are available from a burial ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
This study evaluated to what extent tear film break-up time (TFBUT) could discriminate pathological scores for other clinical tests and explore the associations between them. Dry eye patients (n = 2094) were examined for ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Grid cells in the medial entorhinal cortex (MEC) exhibit remarkable spatial activity patterns with spikes coordinated by theta oscillations driven by the medial septal area (MSA). Spikes from grid cells progress relative ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The research evidence is very strong for high recidivism rates of violence after discharge from forensic facilities. Big data research has found that a substantial proportion of the forensic population with relapse into ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Ductal carcinoma in situ (DCIS) is a preinvasive form of breast cancer with a highly variable potential of becoming invasive and affecting mortality of the patients. Due to the lack of accurate markers of disease progression, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Strict adherence to a gluten-free diet usually leads to clinical and histological remission in celiac disease. Few studies have investigated the prevalence of persistent symptoms in a celiac population. We ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background and aims
Atherogenesis involves a complex interaction between immune cells and lipids, processes greatly influenced by the vascular smooth muscle cell (VSMC) phenotype. The DNA glycosylase NEIL3 has previously ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Introduction
Post-date pregnancies have an increased risk of adverse delivery outcome. Our aim was to explore the association between placenta-associated circulating biomarkers and composite adverse delivery outcome of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Increased risk of cutaneous melanoma and squamous cell carcinoma (SCC) has been reported among petroleum workers, but few studies include females, exposure data on ultraviolet radiation (UVR), and potential ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Objective:
To assess the association between dietary diversity and development among children under 24 months in rural Uganda and to establish other factors that could be associated with development among these ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background: Providing diagnostic and treatment information to patients is a core clinical skill, but evidence for the effectiveness of different information-giving strategies is inconsistent. This systematic review aimed ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Adolescent survivors of pediatric brain tumor (PBT) are a sparsely studied subset of childhood cancer survivors. Sustaining a PBT may complicate the development of executive functions (EFs), which play a vital role in ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
To compare clinical and psychological factors among patients with self-perceived statin-associated muscle symptoms (SAMS), confirmed SAMS, and refuted SAMS in coronary heart disease patients ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract The mechanisms involved in programmed or damage-induced removal of mitochondria by mitophagy remains elusive. Here, we have screened for regulators of PRKN-independent mitophagy using an siRNA library targeting ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Objective To investigate conceptual knowledge about mammographic screening among Norwegian women. Design We administered a cross-sectional, web-based survey. We used multiple-choice questions and a grading rubric published ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Persistent dyspnea is a common symptom after pulmonary embolism (PE). However, the pathophysiology of persistent dyspnea is not fully clarified. This study aimed to explore possible associations between diffuse ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Observational longitudinal data on treatments and covariates are increasingly used to investigate treatment effects, but are often subject to time-dependent confounding. Marginal structural models (MSMs), estimated using ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Serum microfibrillar-associated protein 4 (sMFAP4) has been investigated as a biomarker for various diseases and is demonstrated to show significant gradual increase with severity of liver fibrosis. Ideal biomarkers used ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Epilepsy is one of the most common neurological disorders – estimated to affect at least 65 million worldwide. Most of the epilepsy research has so far focused on how to dampen neuronal discharges and to explain how changes ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Myelin is a lipid-rich membrane that wraps around axons and facilitates rapid action potential propagation. In the brain, myelin is synthesized and maintained by oligodendrocytes. These cells have a high metabolic demand ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Molecular and functional profiling of cancer cell lines is subject to laboratory-specific experimental practices and data analysis protocols. The current challenge therefore is how to make an integrated use of the omics ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background & aims
High quality and precise methods are needed when monitoring changes in body composition among colorectal cancer (CRC) patients and healthy subjects. The aim of this study was to estimate precision of ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background: Successful cardiopulmonary resuscitation after drowning or avalanche is often attributed to hypothermia-induced decrease in metabolism, which adapts the oxygen demand to the amount supplied under cardiac ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Study Objectives:
The aim of this study was to determine the prevalence of insomnia and its association with clinical and psychosocial factors in a large sample of outpatients with coronary heart disease.
Methods:
The ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Cholesteryl esters (CEs) are the water-insoluble transport and storage form of cholesterol. Steroidogenic cells primarily store CEs in cytoplasmic lipid droplet (LD) organelles, as contrasted to the majority of mammalian ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Cell migration is a fundamental biological process of key importance in health and disease. Advances in imaging techniques have paved the way to monitor cell motility. An ever-growing collection of computational tools to ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Oxidative DNA damage in the brain has been implicated in neurodegeneration and cognitive decline. DNA glycosylases initiate base excision repair (BER), the main pathway for oxidative DNA base lesion repair. NEIL1 and NEIL3 ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Information about the contagiousness of new SARS-CoV-2 variants, including the alpha lineage, and how they spread in various locations is essential. Country-specific estimates are needed because local ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Objectives: To study Epstein-Barr virus (EBV) antibody patterns in twin individuals with rheumatoid arthritis (RA) and their healthy co-twins, and to determine the heritability of antibody responses against the EBV encoded ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Disseminated non-dividing (dormant) cancer cells as well as those in equilibrium with the immune response remain the major challenge for successful treatment of cancer. The equilibrium between disseminated dormant cancer ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
In Norway, nodular melanoma is the most fatal melanoma subtype and superficial spreading melanoma the most common, indicating diagnostic challenges. The aim of this study was to assess the clinical suspicion sensitivity ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The growing attention toward the benefits of single-cell RNA sequencing (scRNA-seq) is leading to a myriad of computational packages for the analysis of different aspects of scRNA-seq data. For researchers without advanced ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background MicroRNA (miR)-210 expression is induced by acute and chronic hypoxia and provides prognostic information in patients with aortic stenosis and acute coronary syndrome. We hypothesized that circulating miR-210 ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Major depressive disorder involves changes in synaptic structure and function, but the molecular underpinnings of these changes are still not established. In an initial pilot experiment, whole-brain synaptosome screening ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract. Background: Vitamin A is essential for a wide range of life processes throughout embryogenesis to adult life. With the aim of developing an in vivo model to monitor retinoic acid receptor (RAR) transactivation ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
Excessive bradykinin (BK) generation from high molecular weight kininogen (HK) by plasma kallikrein (PK) due to lack of protease inhibition is central to the pathophysiology of hereditary angioedema (HAE). ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
In molecular biology, advances in high-throughput technologies have made it possible to study complex multivariate phenotypes and their simultaneous associations with high-dimensional genomic and other omics data, a problem ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Delayed-type hypersensitivity arthritis (DTHA) is a recently established experimental model of rheumatoid arthritis (RA) in mice with pharmacological values. Despite an indispensable role of CD4+ T cells in inducing DTHA, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Adequate illumination plays an important part in providing a healthy environment for nursing home patients with dementia. With increasing awareness of non-visual responses to light, new approaches to quantifying illuminance ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The World Health Organization recommends point-of-use fortification with multiple micronutrients powder (MNP) for foods consumed by children aged 6–23 months in populations where anemia prevalence among children under 2 ...
(Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
Variable selection in ultra-high dimensional regression problems has become an important issue. In such situations, penalized regression models may face computational problems and some pre-screening of the variables may ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Immunological non-responders (INR), a subgroup of people living with HIV (PLHIV) who fail to restore CD4 + T cell numbers upon effective antiretroviral treatment, have impaired gut mucosal barrier function and an inferior ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
There is a lack of research regarding blood tests within individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and between patients and healthy controls. We aimed to compare results of routine blood ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Abstract Changes in the body condition of Antarctic minke whales ( Balaenoptera bonaerensis ) have been investigated in a number of studies, but remain contested. Here we provide a new analysis of body condition measurements, ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Acute chest syndrome (ACS) is a severe form of vaso-occlusive crisis, which is a main feature of sickle cell disease (SCD), an inherited hemoglobinopathy. Traditionally, hydroxyurea has been the treatment of choice for SCD ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
As a potent nonviral system for biomolecular delivery to neurons via their axons, we have studied molecular characteristics of lysinated fluorescent dextran nanoconjugates with degrees of conjugation of 0.54–15.2 mol lysine ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The transcription factor MYB is a master regulator in haematopoietic progenitor cells and a pioneer factor affecting differentiation and proliferation of these cells. Leukaemic transformation may be promoted by high MYB ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background: Celiac disease is a chronic autoimmune disease triggered by gluten exposure in genetically predisposed individuals. A life-long intake of a gluten-free (GF) diet is required for its management. Wheat, rye and ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background
The clonal diversity underpinning trends in multidrug resistant Escherichia coli causing bloodstream infections remains uncertain. We aimed to determine the contribution of individual clones to resistance ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Essential E3 ubiquitin ligase HUWE1 (HECT, UBA, and WWE domain containing 1) regulates key factors, such as p53. Although mutations in HUWE1 cause heterogenous neurodevelopmental X-linked intellectual disabilities (XLIDs), ...
(Doctoral thesis / Doktoravhandling, 2021)
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by progressive selective loss of dopaminergic neurons (DN) in substantia nigra pars compacta (SNpc). The etiology of PD is unknown, though environmental ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
The diagnostic work-up of primary Sjögren’s syndrome (pSS) includes quantifying saliva and tear production, evaluation of autoantibodies in serum and histopathological analysis of minor salivary glands. Thus, the potential ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Background & aims
The Global Leadership Initiative on Malnutrition (GLIM) criteria is a step-wise process including a screening tool of choice for risk assessment of malnutrition before assessment of diagnosis and grading ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Hippocampal region CA2 has received increased attention due to its importance in social recognition memory. While its specific function remains to be identified, there are indications that CA2 plays a major role in a variety ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2021)
Insomnia symptoms are associated with increased risk of heart failure (HF) and cardiovascular (CV) mortality. We hypothesised that insomnia symptoms are cross-sectionally associated with increased cardiac troponin I (cTnI), ...