Browsing Institutt for molekylær biovitenskap by Issue Date
Now showing items 1-20 of 121
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2002)Background A method to evaluate and analyze the massive data generated by series of microarray experiments is of utmost importance to reveal the hidden patterns of gene expression. Because of the complexity ...
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(Master thesis / Hovedoppgave, 2003)TCF11 is a regulatory transcription factor belonging to the CNC-bZIP family. The specific biological function of this protein is still unknown. However, knockout studies in mice have revealed its importance during embryo ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2003)Background A limiting factor of cDNA microarray technology is the need for a substantial amount of RNA per labeling reaction. Thus, 20–200 micro-grams total RNA or 0.5–2 micro-grams poly (A) RNA is typically ...
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(Master thesis / Hovedoppgave, 2004)Neurofibromatosis type 1 (NF1) is one of the most common autosomal dominant inherited disorders, and carriers are at greatly increased risk of developing malignant peripheral nerve sheath tumours (MPNST). The NF1 patients ...
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Characterisation of the phosphatidylinositol-3-phosphate 5-kinase, Fab1, in Drosophila melanogaster (Master thesis / Hovedoppgave, 2004)Phosphoinositides play important roles in downregulation of growth factor receptors, such as the epidermal growth factor receptor (EGFR), through regulation of membrane transport and multivesicular body (MVB) biogenesis. ...
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(Master thesis / Hovedoppgave, 2004)Fibroblast growth factors and the four related high-affinity, tyrosine kinase fibroblast growth factor receptors are involved in the regulation of many key cellular responses in developmental and physiological processes. ...
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(Master thesis / Hovedoppgave, 2004)For evolutionary and medical reasons bacterial classification is an important field within microbiology. Before Carl Woese introduced the use of ribosomal RNA sequences for phylogenetic comparison, bacterial classification ...
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(Master thesis / Hovedoppgave, 2004)In contrast to the mammalian major histocompatibility complex (MHC), where the MHC class I and class II loci reside in close vicinity to one another, the bony fishes have unlinked MHC class I and class II. Previous studies ...
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(Master thesis / Hovedoppgave, 2004)Abstract The interest for commercial rearing of Atlantic cod (Gadus morhua) has grown over the last decades. However, heterogeneous growth and cannibalism during early juvenile stages causes serious financial losses. ...
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(Master thesis / Hovedoppgave, 2004)In order to assess the biological role of the flap endonuclease 1 (Fen1), RNA interference (RNAi) was chosen as a method for FEN1 down-regulation in this study. Knock down of FEN1 was achieved both in stable transfected ...
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(Master thesis / Hovedoppgave, 2004)A total of nine single-copy transgenic Arabidopsis thaliana lines displaying varying degrees of silencing of a nos promoter-nptII marker gene (encoding kanamycin-resistance) have been studied, with emphasis on two of these, ...
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(Master thesis / Hovedoppgave, 2004)The rbcL gene is constitutively expressed in the Chlamydomonas chloroplast. The gene encodes the large subunit of ribulose-l,S-bisphosphate carboxylase/oxygenase (Rubisco), the enzyme responsible for CO2 fixation in ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)Background Microarray-based comparative genomic hybridisation (array CGH) is a technique by which variation in relative copy numbers between two genomes can be analysed by competitive hybridisation to DNA ...
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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2004)Background The transcription factor c-Myb is expressed in hematopoietic progenitor cells and other rapidly proliferating tissues, regulating genes important for proliferation, differentiation and survival. ...
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(Master thesis / Hovedoppgave, 2004)Functions of taurine in animal cells have caught interest for a long time. Its efflux activity has been well-studied during cellular volume regulation, but has also been investigated during stimulation with hormones. In ...
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(Master thesis / Masteroppgave, 2005)Abstract Vascular endothelial cells contain typical, elongated vesicles called Weibel-Palade bodies (WPBs), which serve as a storage compartment for biologically active factors involved in hemostasis and inflammation. ...
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(Master thesis / Masteroppgave, 2005)The protein toxin ricin is found in the plant Ricinus communis, and is a useful tool in studies of intracellular traffic. It consists of an enzymatically active A chain and a B chain with lectin properties, joined together ...
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(Master thesis / Hovedoppgave, 2005)Chaperoninene GroEL og GroES er en gruppe molekylære chaperoner som hittil er funnet i alle bakterier. Genene som koder for chaperoniner er vanligvis organisert i operoner på genomet. Den moderat termofile grønne glidende ...
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(Master thesis / Hovedoppgave, 2005)Det humane genet WWOX har blitt identifisert av flere uavhengige forskningsgrupper i forbindelse med studier av strukturelle abnormaliteter av kromosom 16q i ulike krefttyper. Dette genet er lokalisert innenfor kromosom ...
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(Master thesis / Hovedoppgave, 2005)Despite continuous improvement in gene delivery vector technology, development of methods for efficient and specific delivery of therapeutic genes to target cells still remains an important issue in the development of ...