dc.date.accessioned | 2021-10-06T15:39:42Z | |
dc.date.available | 2021-10-06T15:39:42Z | |
dc.date.created | 2021-09-24T12:05:03Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Birkeland, Eline Gharagozlian, Sedegheh Birkeland, Kåre I. Holm, Oda K. S. Thorsby, Per Medbøe Aas, Anne-Marie . Effect of inulin-type fructans on appetite in patients with type 2 diabetes: A randomised controlled crossover trial. Journal of Nutritional Science (JNS). 2021, 10, 1-11 | |
dc.identifier.uri | http://hdl.handle.net/10852/88769 | |
dc.description.abstract | Abstract
The aim of the study was to investigate the effect of prebiotic fibres on appetite-regulating hormones, subjective feeling of appetite and energy intake in subjects with type 2 diabetes. Data presented are secondary outcomes of a study investigating the effect of prebiotics on glucagon-like peptide-1 and glycaemic regulation. We conducted a randomised and placebo-controlled crossover trial to evaluate the effects of 16 g/d of inulin-type fructans or a control supplement (maltodextrin) for 6 weeks in randomised order, with a 4-week washout period in-between, on appetite in thirty-five men and women with type 2 diabetes. Data were collected at visits before and after each treatment: plasma concentration of the satiety-related peptides ghrelin and peptide YY (PYY) were assessed during a standardised mixed meal. The subjective sensation of appetite was evaluated in response to an ad libitum lunch by rating the visual analogue scale. Twenty-nine individuals (twelve women) were included in the analyses. Compared to control treatment, the prebiotics did not affect ghrelin ( P =0⋅71) or the ratings of hunger ( P = 0⋅62), satiety ( P = 0⋅56), fullness ( P = 0⋅73) or prospective food consumption ( P = 0⋅98). Energy intake also did not differ between the treatments. However, the response of PYY increased significantly after the control treatment with mean ( sem ) 11⋅1 (4⋅3) pg/ml when compared to the prebiotics −0⋅3 (4⋅3) pg/ml ( P = 0⋅013). We observed no effect of inulin-type fructans on appetite hormones, subjective feeling of appetite or energy intake in patients with type 2 diabetes. | |
dc.language | EN | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | Effect of inulin-type fructans on appetite in patients with type 2 diabetes: A randomised controlled crossover trial | |
dc.type | Journal article | |
dc.creator.author | Birkeland, Eline | |
dc.creator.author | Gharagozlian, Sedegheh | |
dc.creator.author | Birkeland, Kåre I. | |
dc.creator.author | Holm, Oda K. S. | |
dc.creator.author | Thorsby, Per Medbøe | |
dc.creator.author | Aas, Anne-Marie | |
cristin.unitcode | 185,53,11,21 | |
cristin.unitname | Avdeling for klinisk service | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.cristin | 1938147 | |
dc.identifier.bibliographiccitation | info:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal of Nutritional Science (JNS)&rft.volume=10&rft.spage=1&rft.date=2021 | |
dc.identifier.jtitle | Journal of Nutritional Science (JNS) | |
dc.identifier.volume | 10 | |
dc.identifier.doi | https://doi.org/10.1017/jns.2021.70 | |
dc.identifier.urn | URN:NBN:no-91387 | |
dc.type.document | Tidsskriftartikkel | |
dc.type.peerreviewed | Peer reviewed | |
dc.source.issn | 2048-6790 | |
dc.identifier.fulltext | Fulltext https://www.duo.uio.no/bitstream/handle/10852/88769/2/Effect-of-inulin-type-fructans-on-appetite-in-patients-with-type-2-diabetes-a-randomised-controlled-crossover-trial.pdf | |
dc.type.version | PublishedVersion | |
cristin.articleid | e72 | |