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dc.date.accessioned2018-09-18T14:36:29Z
dc.date.available2018-09-18T14:36:29Z
dc.date.created2018-02-20T15:19:30Z
dc.date.issued2018
dc.identifier.citationJohansen, Jeanette Schultz Havnes, Kjerstin Halvorsen, Kjell H. Haustreis, Stine-Mari Skaue, Lillann Wilsgård Kamycheva, Elena Mathiesen, Liv Viktil, Kirsten Kilvik Granås, Anne Gerd Garcia, Beate Hennie . Interdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (IMMENSE study): study protocol for a randomised controlled trial. BMJ Open. 2018
dc.identifier.urihttp://hdl.handle.net/10852/64812
dc.description.abstractIntroduction: Drug-related problems (DRPs) are common in the elderly, leading to suboptimal therapy, hospitalisations and increased mortality. The integrated medicines management (IMM) model is a multifactorial interdisciplinary methodology aiming to optimise individual medication therapy throughout the hospital stay. IMM has been shown to reduce readmissions and drug-related hospital readmissions. Using the IMM model as a template, we have designed an intervention aiming both to improve medication safety in hospitals, and communication across the secondary and primary care interface. This paper presents the study protocol to explore the effects of the intervention with regard to healthcare use, health-related quality of life (HRQoL) and medication appropriateness in elderly patients. Methods and analysis: A total of 500 patients aged ≥70 years will be included and randomised to control (standard care) or intervention group (1:1). The intervention comprises five steps mainly performed by pharmacists: (1) medication reconciliation at admission, (2) medication review during hospital stay, (3) patient counselling about the use of medicines, (4) a comprehensible and patient-friendly medication list with explanations in discharge summary and (5) postdischarge phone calls to the primary care level. The primary outcome is the difference between intervention and control patients in the rate of emergency medical visits (acute readmissions and visits to emergency department) 12 months after discharge. Secondary outcomes include length of index hospital stay, time to first readmission, mortality, hip fractures, strokes, medication changes, HRQoL and medication appropriateness. Patient inclusion started in September 2016. Ethics and dissemination: The trial was approved by the Norwegian Centre for Research Data and the Norwegian Data Protection Authority. We aim to publish the results in international peer-reviewed open access journals, at national and international conferences, and as part of two PhD theses.en_US
dc.languageEN
dc.publisherBMJ Publishing Group
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.titleInterdisciplinary collaboration across secondary and primary care to improve medication safety in the elderly (IMMENSE study): study protocol for a randomised controlled trialen_US
dc.typeJournal articleen_US
dc.creator.authorJohansen, Jeanette Schultz
dc.creator.authorHavnes, Kjerstin
dc.creator.authorHalvorsen, Kjell H.
dc.creator.authorHaustreis, Stine-Mari
dc.creator.authorSkaue, Lillann Wilsgård
dc.creator.authorKamycheva, Elena
dc.creator.authorMathiesen, Liv
dc.creator.authorViktil, Kirsten Kilvik
dc.creator.authorGranås, Anne Gerd
dc.creator.authorGarcia, Beate Hennie
cristin.unitcode185,15,23,0
cristin.unitnameFarmasøytisk institutt
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.cristin1567109
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=BMJ Open&rft.volume=&rft.spage=&rft.date=2018
dc.identifier.jtitleBMJ Open
dc.identifier.doihttp://dx.doi.org/10.1136/bmjopen-2017-020106
dc.identifier.urnURN:NBN:no-67348
dc.type.documentTidsskriftartikkelen_US
dc.type.peerreviewedPeer reviewed
dc.source.issn2044-6055
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/64812/2/article74159.pdf
dc.type.versionPublishedVersion


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