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dc.date.accessioned2015-10-06T14:24:33Z
dc.date.available2015-10-06T14:24:33Z
dc.date.created2011-01-14T17:04:01Z
dc.date.issued2010
dc.identifier.citationLyche, Pia Elisabeth Jonassen, Rune Stiles, Tore C Ulleberg, Pål Landrø, Nils Inge . Cognitive control functions in unipolar major deepression with or without co-morbid anxiety. Frontiers in Psychiatry. 2010, 1, 1-9
dc.identifier.urihttp://hdl.handle.net/10852/46172
dc.description.abstractBackground: Impaired cognitive control functions have been demonstrated in both major depression (MDD) and anxiety disorder (A), but few studies have systematically examined the impact of MDD with co-morbid A (MDDA), which is the main aim of this study. Method: We compared patients with MDD with (MDDA; n = 24) and without co-morbid A (n = 37) to a group of healthy controls (HC; n = 92) on three subtests from the Cambridge Neuropsychological Test Automated Battery; intra–extra dimensional, stop signal task, and spatial working memory. These tasks correspond to a theoretical model consisting of three separable but interrelated executive control functions: Shifting, Inhibition, and Updating. A simple psychomotor speed measure was also included. Results: After controlling for age, gender, and education level, the results showed that the MDDA group displayed significantly impaired performance on the functions Shifting and Updating compared to HC. There emerged no significant differences between any of the patient groups and HC regarding Inhibition. The pure MDD group did not display dysfunctions relative to the HC group on the main executive control variables, but displayed slowed psychomotor speed. Contrary to expectation there were no significant differences between the MDDA and the MDD groups. Conclusion: Co-morbid anxiety should be taken into account when studying cognitive control functions in major depression. © 2010 Lyche, Jonassen, Stiles, Ulleberg and Landrø. This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.en_US
dc.languageEN
dc.language.isoenen_US
dc.publisherFrontiers Research Foundation
dc.titleCognitive control functions in unipolar major deepression with or without co-morbid anxietyen_US
dc.typeJournal articleen_US
dc.creator.authorLyche, Pia Elisabeth
dc.creator.authorJonassen, Rune
dc.creator.authorStiles, Tore C
dc.creator.authorUlleberg, Pål
dc.creator.authorLandrø, Nils Inge
cristin.unitcode185,17,5,0
cristin.unitnamePsykologisk institutt
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.cristin524541
dc.identifier.bibliographiccitationinfo:ofi/fmt:kev:mtx:ctx&ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Frontiers in Psychiatry&rft.volume=1&rft.spage=1&rft.date=2010
dc.identifier.jtitleFrontiers in Psychiatry
dc.identifier.volume1
dc.identifier.startpage1
dc.identifier.endpage9
dc.identifier.doihttp://dx.doi.org/10.3389/fpsyt.2010.00149
dc.identifier.urnURN:NBN:no-50366
dc.type.documentTidsskriftartikkelen_US
dc.type.peerreviewedPeer reviewed
dc.source.issn1664-0640
dc.identifier.fulltextFulltext https://www.duo.uio.no/bitstream/handle/10852/46172/2/fpsyt-01-00149.pdf
dc.type.versionPublishedVersion
cristin.articleid149


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