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(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Background The present study explored and compared the immediate responses in markers of inflammation and angiogenesis in maintenance heart transplant (HTx) recipients before, during and after sessions of high-intensity ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2014)
Background Dilated cardiomyopathy is characterized by left ventricular dilatation and dysfunction. Inflammation and adverse remodeling of the extracellular matrix may be involved in the pathogenesis. Statins reduce levels ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Background We have previously demonstrated an association between increased sFRP3 expression and adverse outcome in a population of HF irrespective of cause and left ventricular ejection fraction. In this study we evaluated ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2011)
Background
In the western world, heart failure (HF) is one of the most important causes of cardiovascular mortality. Supplement with n-3 polyunsaturated fatty acids (PUFA) has been shown to improve cardiac ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2013)
Background
Novel and robust cardiovascular (CV) markers are needed to improve CV morbidity and mortality risk prediction in type 2 diabetes (T2D). We assessed the long term predictive value of 4 novel CV ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
Myocardial infarction (MI) triggers a reparative response involving fibroblast proliferation and differentiation driving extracellular matrix modulation necessary to form a stabilizing scar. Recently, it was shown that a ...
Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2017)
The Wingless (Wnt) pathway has been implicated in the pathogenesis of dilated cardiomyopathy (DCM). To explore the role of Wnt modulators Wnt5a and sFRP3 in DCM patients we analyzed the expression of Wnt5a and sFRP3 in ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Objective: It is unclear if activation of inflammatory pathways regulates proprotein convertase subtilisin-kexin type 9 (PCSK9) levels.
Approach: We evaluated (1) the temporal course of serum PCSK9 during hospitalisation ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2015)
Aim Cardiac inflammation is important in the pathogenesis of heart failure. However, the consequence of systemic inflammation on concomitant established heart failure, and in particular diastolic heart failure, is less ...
(Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
Aims: Heart failure (HF) is a multifactorial disease. Current treatments target only a fraction of the putative pathophysiological pathways. In patients with HF, reduced cardiac output and congestion cause increased gut ...