Browsing Institutt for klinisk medisin by Author "Xia, Dajing"

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  • WIPI2 positively regulates mitophagy by promoting mitochondrial recruitment of VCP 
    Lu, Guang; Tan, Hayden Weng Siong; Schmauck-Medina, Tomás Alejandro; Wang, Liming; Chen, Jiaqing; Cho, Yik-Lam; Chen, Kelie; Zhang, Jing-Zi; He, Weifeng; Wu, Yihua; Xia, Dajing; Zhou, Jing; Fang, Fei; Fang, Lei; Liu, Wei; Shen, Han-Ming (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    The mammalian Atg18 ortholog WIPI2 is a key regulator of LC3 lipidation to promote autophagosome biogenesis during nonselective macroautophagy, while its functions in selective autophagy such as mitophagy remain largely ...