Browsing Institutt for klinisk medisin by Author "Vaage, John T."

Now showing items 1-20 of 21

  • Covid-19-pasienter behandlet med rekonvalesensplasma 
    Nissen-Meyer, Lise Sofie Haug; Macpherson, Magnhild Eide; Skeie, Linda Gail; Hvalryg, Marte; LLOHN, ABID HUSSAIN; Steinsvåg, Tine Torsvik; Fenstad, Mona H.; Tveita, Anders; Kristoffersen, Einar Klæboe; Sundic, Tatjana; Lund-Johansen, Fridtjof; Vaage, John T.; Flesland, Øystein; Dyrhol-Riise, Anne Ma; Holter, Jan Cato; Hervig, Tor Audun; Fevang, Børre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    BAKGRUNN I Norge er behandling med covid-19-rekonvalesensplasma gitt gjennom NORPLASMA-prosjektet. I begynnelsen ble behandlingen tilbudt kritisk syke pasienter etter individuell vurdering, men fra desember 2020 ble ...
  • Frontline Science: A hyporesponsive subset of rat NK cells negative for Ly49s3 and NKR-P1B are precursors to the functionally mature NKR-P1B+ subset 
    Sudworth, Amanda; Vaage, John T.; Inngjerdingen, Marit; Kveberg, Lise (Journal article / Tidsskriftartikkel / SubmittedVersion, 2017)
    Rat NK cells are divided into major subsets expressing either Ly49 receptors or the inhibitory NKR‐P1B receptor in conjunction with NKG2A/C/E receptors. A minor subset of NKp46+ cells lacking expression of both Ly49 receptors ...
  • HLA-DRB3*01:01 exhibits a dose-dependent impact on HPA-1a antibody levels in HPA-1a-immunized women 
    Kjeldsen-Kragh, Jens; Titze, Thomas Larsen; Lie, Benedicte Alexandra; Vaage, John T.; Kjær, Mette (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    HLA-DRB3*01:01 is a predisposing factor for human platelet antigen 1a (HPA-1a) immunization, which is responsible for most cases of fetal and neonatal alloimmune thrombocytopenia. The aim of this study was to investigate ...
  • Humoral and cellular immune responses to two and three doses of SARS-CoV-2 vaccines in rituximab-treated patients with rheumatoid arthritis: a prospective, cohort study 
    Jyssum, Ingrid; Kared, Hassen; Tran, Trung; Tveter, Anne Therese; Provan, Sella Aarrestad; Sexton, Joseph; Jørgensen, Kristin Kaasen; Jahnsen, Jørgen; Kro, Grete Anette Birkeland; Warren, David; Vaage, Eline Benno; Kvien, Tore Kristian; Nissen-Meyer, Lise Sofie Haug; Anderson, Ane Marie; Grødeland, Gunnveig; Haavardsholm, Espen A.; Vaage, John T.; Mjaaland, Siri; Syversen, Silje Watterdal; Lund-Johansen, Fridtjof; Munthe, Ludvig Andre; Goll, Guro Løvik (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2021)
    Background In rituximab-treated patients with rheumatoid arthritis, humoral and cellular immune responses after two or three doses of SARS-CoV-2 vaccines are not well characterised. We aimed to address this knowledge ...
  • Humoral immune response to SARS-CoV-2 vaccination in patients with inflammatory bowel disease on immunosuppressive medication: association to serum drug levels and disease type 
    Jørgensen, Kristin Kaasen; Høivik, Marte Lie; Chopra, Adity; Saltyte Benth, Jurate; Ricanek, Petr; Moum, Bjørn Allan; Jyssum, Ingrid; Bolstad, Nils; Warren, David; Vaage, John T.; Munthe, Ludvig Andre; Lundin, Knut Erik Aslaksen; Anisdahl, Karoline; Syversen, Silje Watterdal; Goll, Guro Løvik; Lund-Johansen, Fridtjof; Medhus, Asle Wilhelm; Jahnsen, Jørgen (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Objectives Immune responses following SARS-CoV-2 vaccination in patients with inflammatory bowel disease (IBD) are not well characterized. The aims of this study were to explore the serological response associated with ...
  • Humoral vaccine response and breakthrough infections in kidney transplant recipients during the COVID-19 pandemic: a nationwide cohort study 
    Hovd, Markus Herberg; Åsberg, Anders; Munthe, Ludvig Andre; Heldal, Kristian; Reisæter, Anna Varberg; Vaage, John T.; Lund-Johansen, Fridtjof; Midtvedt, Karsten (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Kidney transplant recipients (KTRs) experienced reduced SARS-CoV-2 vaccine response and were at increased risk of severe COVID-19. It is unknown if level of vaccine induced anti-receptor binding domain IgG ...
  • Hybrid and SARS-CoV-2-vaccine immunity in kidney transplant recipients 
    Kared, Hassen; Alirezaylavasani, Amin; Lund, Katrine Persgård; Chopra, Adity; Tietze, Lisa; de Matos Kasahara, Taissa; Goll, Guro Løvik; Grødeland, Gunnveig; Kaarbø, Mari; Reisæter, Anna Varberg; Hovd, Markus Herberg; Vaage, John T.; Lund-Johansen, Fridtjof; Midtvedt, Karsten; Åsberg, Anders; Munthe, Ludvig Andre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Background Kidney transplant recipients (KTR) are at high risk for severe COVID-19 and have demonstrated poor response to vaccination, making it unclear whether successive vaccinations offer immunity and protection. ...
  • Immune responses in Omicron SARS-CoV-2 breakthrough infection in vaccinated adults 
    Kared, Hassen; Wolf, Asia-Sophia Fumika Michaela; Alirezaylavasani, Amin; Ravussin, Anthony; Solum, Guri; Tran, Trung The; Lund-Johansen, Fridtjof; Vaage, John T.; Nissen-Meyer, Lise Sofie Haug; Nygaard, Unni Cecilie; Hungnes, Olav; Robertson, Anna Hayman; Næss, Lisbeth Meyer; Trogstad, Lill; Magnus, Per Minor; Munthe, Ludvig Andre; Mjaaland, Siri (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract The SARS-CoV-2 Omicron variant has more than 15 mutations in the receptor binding domain of the Spike protein enabling increased transmissibility and viral escape from antibodies in vaccinated individuals. It is ...
  • Immune responses to SARS-CoV-2 vaccines in celiac disease 
    Ibsen, Jostein Holen; Chopra, Adity; Vaage, Eline Benno; Vaage, John T.; Lund-Johansen, Fridtjof; Lundin, Knut (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background and aims SARS-CoV-2 infection and development of the disease COVID-19 is a serious threat to our society. Effective vaccines have now entered the market, but most patient populations were not included in the ...
  • Immunogenicity and safety of a three-dose SARS-CoV-2 vaccination strategy in patients with immune-mediated inflammatory diseases on immunosuppressive therapy 
    Syversen, Silje Watterdal; Jyssum, Ingrid; Tveter, Anne Therese; Sexton, Joseph; Christensen, Ingrid Egeland; Tran, Trung; Hammersbøen, Kristin Reine; Mjaaland, Siri; Warren, David; Kvien, Tore Kristian; Chopra, Adity; Kro, Grete Anette Birkeland; Jahnsen, Jørgen; Munthe, Ludvig Andre; Haavardsholm, Espen A.; Grødeland, Gunnveig; Vaage, John T.; Provan, Sella Aarrestad; Jørgensen, Kristin Kaasen; Goll, Guro Løvik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Objectives Humoral vaccine responses to SARS-CoV-2 vaccines are impaired and short lasting in patients with immune-mediated inflammatory diseases (IMID) following two vaccine doses. To protect these vulnerable patients ...
  • Immunogenicity and Safety of Standard and Third-Dose SARS-CoV-2 Vaccination in Patients Receiving Immunosuppressive Therapy 
    Syversen, Silje Watterdal; Jyssum, Ingrid; Tveter, Anne Therese; Tran, Trung; Sexton, Joseph; Provan, Sella Aarrestad; Mjaaland, Siri; Warren, David; Kvien, Tore Kristian; Grødeland, Gunnveig; Nissen-Meyer, Lise Sofie Haug; Ricanek, Petr; Chopra, Adity; Andersson, Ane Marte; Kro, Grete Anette Birkeland; Jahnsen, Jørgen; Munthe, Ludvig Andre; Haavardsholm, Espen A.; Vaage, John T.; Lund-Johansen, Fridtjof; Jørgensen, Kristin Kaasen; Goll, Guro Løvik (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Objective Immunogenicity and safety following receipt of the standard SARS–CoV-2 vaccination regimen in patients with immune-mediated inflammatory diseases (IMIDs) are poorly characterized, and data after receipt of the ...
  • Mode of perfusion influences infarct size, coronary flow and stress kinases in the isolated mouse heart 
    Bliksøen, Marte; Rutkovskiy, Arkady; Vaage, John T.; Stensløkken, Kåre-Olav (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2017)
    Aim: The isolated, retrogradely perfused heart (modified Langendorff model) is a widely used method in experimental heart research. The presence of an intraventricular balloon is necessary to get functional measurements. ...
  • People who use drugs show no increase in pre-existing T-cell cross-reactivity toward SARS-CoV-2 but develop a normal polyfunctional T-cell response after standard mRNA vaccination 
    Gainullin, Murat; Federico, Lorenzo; Osen, Julie Røkke; Chaban, Viktoriia; Kared, Hassen; Alirezaylavasani, Amin; Lund-Johansen, Fridtjof; Wildendahl, Gull; Jacobsen, Jon-Aksel; Sarwar Anjum, Hina; Stratford, Richard; Tennøe, Simen; Malone, Brandon; Clancy, Trevor; Vaage, John T.; Henriksen, Kathleen; Wüsthoff, Linda Elise; Munthe, Ludvig Andre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    People who use drugs (PWUD) are at a high risk of contracting and developing severe coronavirus disease 2019 (COVID-19) and other infectious diseases due to their lifestyle, comorbidities, and the detrimental effects of ...
  • Prevalence of antibodies against SARS-CoV-2 in the Norwegian population, August 2021 
    Tunheim, Gro; Rø, Gunnar Øyvind Isaksson; Chopra, Adity; Aase, Audun; Kran, Anne-Marte Bakken; Vaage, John T.; Lund-Johansen, Fridtjof; Hungnes, Olav (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background One year into the COVID-19 pandemic, the cumulative number of confirmed COVID-19 cases in Norway was still low. In January 2021, when the Norwegian COVID-19 vaccination campaign started, the national ...
  • Prevalent and immunodominant CD8 T cell epitopes are conserved in SARS-CoV-2 variants 
    Meyer, Saskia; Blaas, Isaac; Bollineni, Ravi Chand; Delic-Sarac, Marina; Tran, Trung; Knetter, Cathrine; Dai, Kezheng; Madssen, Torfinn Støve; Vaage, John T.; Gustavsen, Alice; Yang, Weiwen; Nissen-Meyer, Lise Sofie Haug; Douvlataniotis, Karolos; Laos, Maarja; Nielsen, Morten Milek; Thiede, Bernd; Søraas, Arne Vasli Lund; Lund-Johansen, Fridtjof; Rustad, Even Holth; Olweus, Johanna (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    The emergence of SARS-CoV-2 variants of concern (VOC) is driven by mutations that mediate escape from neutralizing antibodies. There is also evidence that mutations can cause loss of T cell epitopes. However, studies on ...
  • Rituximab-treated patients with lymphoma develop strong CD8 T-cell responses following COVID-19 vaccination 
    Riise, Jon; Meyer, Saskia; Blaas, Isaac; Chopra, Adity; Tran, Trung; Delic-Sarac, Marina; Hestdalen, Malu Lian; Brodin, Ellen Elisabeth; Rustad, Even Holth; Dai, Ke-Zheng; Vaage, John T.; Nissen-Meyer, Lise Sofie Haug; Sund, Fredrik; Wader, Karin Fahl; Bjørnevik, Anne Turid; Meyer, Peter Albert; Nygaard, Gro Owren; König, Marton; Smeland, Sigbjørn; Lund-Johansen, Fridtjof; Olweus, Johanna; Kolstad, Arne (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    B-cell depletion induced by anti-cluster of differentiation 20 (CD20) monoclonal antibody (mAb) therapy of patients with lymphoma is expected to impair humoral responses to severe acute respiratory syndrome coronavirus-2 ...
  • Robust spike-specific CD4+ and CD8+ T cell responses in SARS-CoV-2 vaccinated hematopoietic cell transplantation recipients: a prospective, cohort study 
    Federico, Lorenzo; Tvedt, Tor Henrik Anderson; Gainullin, Murat; Osen, Julie Røkke; Chaban, Viktoriia; Lund, Kathrine Persgård; Tietze, Lisa; Tran, Trung; Lund-Johansen, Fridtjof; Kared, Hassen; Lind, Andreas; Vaage, John T.; Stratford, Richard; Tennøe, Simen; Malone, Brandon; Clancy, Trevor; Myhre, Anders Eivind; Gedde-Dahl, Tobias; Munthe, Ludvig Andre (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Poor overall survival of hematopoietic stem cell transplantation (HSCT) recipients who developed COVID-19 underlies the importance of SARS-CoV-2 vaccination. Previous studies of vaccine efficacy have reported weak humoral ...
  • T cell responses to SARS-CoV-2 vaccination differ by disease-modifying therapy for multiple sclerosis 
    Wolf, Asia-Sophia Fumika Michaela; Ravussin, Anthony; König, Marton; Øverås, Mathias Herstad; Solum, Guri; Kjønstad, Ingrid Fadum; Chopra, Adity; Holmøy, Trygve; Harbo, Hanne-Cathrin Flinstad; Syversen, Silje Watterdal; Jørgensen, Kristin Kaasen; Høgestøl, Einar August; Vaage, John T.; Celius, Elisabeth Gulowsen; Lund-Johansen, Fridtjof; Munthe, Ludvig Andre; Nygaard, Gro Owren; Mjaaland, Siri (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2023)
    Immune responses in people with multiple sclerosis (pwMS) receiving disease-modifying therapies (DMTs) have been of significant interest throughout the COVID-19 pandemic. Lymphocyte-targeting immunotherapies, including ...
  • The persistence of anti-Spike antibodies following two SARS-CoV-2 vaccine doses in patients on immunosuppressive therapy compared to healthy controls—a prospective cohort study 
    Christensen, Ingrid E.; Jyssum, Ingrid; Tveter, Anne T.; Sexton, Joseph; Tran, Trung T.; Mjaaland, Siri; Kro, Grete B.; Kvien, Tore K.; Warren, David J.; Jahnsen, Jørgen; Munthe, Ludvig A.; Haavardsholm, Espen A.; Vaage, John T.; Grødeland, Gunnveig; Lund-Johansen, Fridtjof; Jørgensen, Kristin K.; Syversen, Silje W.; Goll, Guro L.; Provan, Sella A. (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Background The durability of vaccine-induced humoral immunity against SARS-CoV-2 in patients with immune-mediated inflammatory diseases (IMIDs) on immunosuppressive therapy is not known. The aim of this ...
  • Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants 
    Tran, Trung The; Vaage, Eline Benno; Mehta, Adi; Chopra, Adity; Tietze, Lisa; Kolderup, Anette; Anthi, Aina Karen; König, Marton; Nygaard, Gro Owren; Lind, Andreas; Müller, Fredrik; Nissen-Meyer, Lise Sofie Haug; Magnus, Per Minor; Trogstad, Lill; Mjaaland, Siri; Søraas, Arne Vasli; Midtvedt, Karsten; Åsberg, Anders; Barratt-Due, Andreas; Medhus, Asle Wilhelm; Høivik, Marte Lie; Lundin, Knut; Karlsen, Randi Fuglaas; Dahle, Reidun; Danielsson, Karin; Thomassen, Kristine Stien; Kro, Grete Anette Birkeland; Cox, Rebecca Jane; Zhou, Fan; Langeland, Nina; Aukrust, Pål; Melum, Espen; Åvitsland, Tone Lise; Wiencke, Kristine; Holter, Jan Cato; Munthe, Ludvig Andre; Grødeland, Gunnveig; Andersen, Jan Terje; Vaage, John T.; Lund-Johansen, Fridtjof (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Abstract Diagnostic assays currently used to monitor the efficacy of COVID-19 vaccines measure levels of antibodies to the receptor-binding domain of ancestral SARS-CoV-2 (RBDwt). However, the predictive value for protection ...