Browsing Institutt for klinisk medisin by Author "Fan, Zhirui"

Now showing items 1-7 of 7

  • Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro 
    Fan, Zhirui; Li, Lifeng; Li, Xiaoli; Zhang, Meng; Dou, Mengmeng; Zhao, Jing; Cao, Jing; Deng, Xiaoming; Zhang, Mingzhi; Li, Huixiang; Suo, Zhenhe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2019)
    Abnormalities in tricarboxylic acid (TCA) cycle function were related to a variety of pathological processes. Fumarate hydratase (FH) is a required enzyme in the TCA cycle. To explore the general influence of FH knockout, ...
  • Clinical Significance of Retinoic Acid Receptor Beta Promoter Methylation in Prostate Cancer: A Meta-Analysis 
    Dou, Mengmeng; Zhou, Xueliang; Fan, Zhirui; Ding, Xianfei; Li, Lifeng; Wang, Shuling; Xue, Wenhua; Wang, Hui; Suo, Zhenhe; Deng, Xiaoming (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background/Aims: Retinoic acid receptor beta (RAR beta) is a retinoic acid receptor gene that has been shown to play key roles during multiple cancer processes, including cell proliferation, apoptosis, migration and invasion. ...
  • Generation of an oxoglutarate dehydrogenase knockout rat model and the effect of a high-fat diet 
    Fan, Zhirui; Li, Lifeng; Li, Xiaoli; Zhang, Meng; Zhong, Yali; Li, Yaqing; Yu, Dandan; Cao, Jing; Zhao, Jing; Deng, Xiaoming; Zhang, Mingzhi; Wen, Jian-Guo; Liu, Zhangsuo; Goscinski, Mariusz Adam; Berge, Viktor; Nesland, Jahn M; Suo, Zhenhe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Although abnormal metabolism in metabolic syndrome and tumours has been well described, the relationship between oxoglutarate dehydrogenase (OGDH) and obesity-related diseases is still largely unknown. This study aimed to ...
  • High level of lncRNA H19 expression is associated with shorter survival in esophageal squamous cell cancer patients 
    Li, Xiangyu; Yang, Haijun; Wang, Jianbo; Li, Xiufang; Fan, Zhirui; Zhao, Jing; Liu, Lan; Zhang, Mingzhi; Goscinski, Mariusz Adam; Wang, Junsheng; Xu, Ruiping; Fan, Huijie; Li, Huixiang; Suo, Zhenhe (Journal article / Tidsskriftartikkel / AcceptedVersion; Peer reviewed, 2019)
    Aim Long non-coding RNA (lncRNA) is currently considered to play an important regulatory role in various diseases, including tumors, at present a hot topic in research. As a non-coding transcription product of imprinted ...
  • High SRPX2 protein expression predicts unfavorable clinical outcome in patients with prostate cancer 
    Zhang, Meng; Li, Xiaoli; Fan, Zhirui; Zhao, Jing; Liu, Shuzheng; Zhang, Mingzhi; Li, Huixiang; Goscinski, Mariusz Adam; Fan, Huijie; Suo, Zhenhe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2018)
    Background: Sushi repeat-containing protein X-linked 2 (SRPX2) is overexpressed in a variety of different tumor tissues and correlated with poor prognosis in patients. Little research focuses on the role of SRPX2 expression ...
  • MPC1 and MPC2 expressions are associated with favorable clinical outcomes in prostate cancer 
    Li, Xiaoli; Ji, Yasai; Han, Gaoyang; Li, Xiaoran; Fan, Zhirui; Li, Yaqing; Zhong, Yali; Cao, Jing; Zhao, Jing; Zhang, Mingzhi; Wen, Jianguo; Goscinski, Mariusz A; Nesland, Jahn M; Suo, Zhenhe (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2016)
    Background Cancer cells exhibit an altered metabolism, which is characterized by a preference for aerobic glycolysis more than mitochondrial oxidation of pyruvate. Mitochondrial pyruvate carrier 1 (MPC1) ...
  • Promoting role of pentraxin-3 in esophageal squamous cell carcinoma 
    Fan, Zhirui; Zheng, Yuanyuan; Li, Xiaoli; Deng, Xiaoming; Ba, Yan; Feng, Kun; Su, Jin; Wang, Hui; Suo, Zhenhe; Li, Lifeng (Journal article / Tidsskriftartikkel / PublishedVersion; Peer reviewed, 2022)
    Pentraxin 3 (PTX3) is an inflammatory molecule that is closely related to the proliferation, invasion, and metastasis of cancer. In order to explore the role of PTX3 in the occurrence and development of esophageal carcinoma ...